Reduced base-base interactions between the DNA seed and RNA target are the major determinants of a significant reduction in the off-target effect due to DNA-seed-containing siRNA

20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science

Volumn , Issue , 2009, Pages 298-304

  Ui Tei, Kumiko ^a   Nishi, Kenji ^a   Naito, Yuki ^a   Zenno, Shuhei ^a,b   Juni, Aya ^a   Saigo, Kaoru ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b MAEBASHI INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CLASS I; GENE SILENCING; MELTING TEMPERATURES; TARGET GENES;

COMPLEXATION; DNA; GENES; GENETIC ENGINEERING; NUCLEIC ACIDS; RNA; SEED; SOCIAL SCIENCES; THERMODYNAMIC STABILITY; THERMODYNAMICS;

TARGETS;

EID: 77950959322     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/MHS.2009.5351913     Document Type: Conference Paper

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