-
1
-
-
0034614637
-
The hallmark of cancer
-
Hanahan D., Weinberg R.A. The hallmark of cancer. Cell 2000, 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
Sjöblom T., Jones S., Wood L.D., et al. The consensus coding sequences of human breast and colorectal cancers. Science 2006, 314:268-274.
-
(2006)
Science
, vol.314
, pp. 268-274
-
-
Sjöblom, T.1
Jones, S.2
Wood, L.D.3
-
3
-
-
1542619848
-
Cancer as a robust system: implications for anticancer therapy
-
Kitano H. Cancer as a robust system: implications for anticancer therapy. Nat Rev Cancer 2004, 4:227-235.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 227-235
-
-
Kitano, H.1
-
4
-
-
0142219899
-
Evolutionary dynamics of mutator phenotypes in cancer: implications for chemotherapy
-
Komarova N.L., Wodarz D. Evolutionary dynamics of mutator phenotypes in cancer: implications for chemotherapy. Cancer Res 2003, 63:6635-6642.
-
(2003)
Cancer Res
, vol.63
, pp. 6635-6642
-
-
Komarova, N.L.1
Wodarz, D.2
-
5
-
-
33749240527
-
The tumor microenvironment in the post-Paget era
-
Witz I.P., Levy-Nissenbaum O. The tumor microenvironment in the post-Paget era. Cancer Lett 2006, 242:1-10.
-
(2006)
Cancer Lett
, vol.242
, pp. 1-10
-
-
Witz, I.P.1
Levy-Nissenbaum, O.2
-
6
-
-
33751217466
-
Tumor morphology and phenotypic evolution driven by selective pressure from microenvironment
-
Anderson A.R.A., Weaver A.M., Cummings P.T., Quaranta V. Tumor morphology and phenotypic evolution driven by selective pressure from microenvironment. Cell 2006, 127:905-915.
-
(2006)
Cell
, vol.127
, pp. 905-915
-
-
Anderson, A.R.A.1
Weaver, A.M.2
Cummings, P.T.3
Quaranta, V.4
-
7
-
-
48349113618
-
Can cancer be reversed by engineering the tumor microenvironment?
-
Ingber D.E. Can cancer be reversed by engineering the tumor microenvironment?. Semin Cancer Biol 2008, 18:356-364.
-
(2008)
Semin Cancer Biol
, vol.18
, pp. 356-364
-
-
Ingber, D.E.1
-
8
-
-
34347354221
-
Testing optimality with experimental evolution: Lysis time in bacteriophage
-
Heineman R.H., Bull J.J. Testing optimality with experimental evolution: Lysis time in bacteriophage. Evolution 2007, 61:1695-1709.
-
(2007)
Evolution
, vol.61
, pp. 1695-1709
-
-
Heineman, R.H.1
Bull, J.J.2
-
9
-
-
67349224634
-
Mixed immunotherapy and chemotherapy of tumors: feedback design and model updating schemes
-
Chareyron S., Alamir M. Mixed immunotherapy and chemotherapy of tumors: feedback design and model updating schemes. J Theor Biol 2009, 258:444-454.
-
(2009)
J Theor Biol
, vol.258
, pp. 444-454
-
-
Chareyron, S.1
Alamir, M.2
-
10
-
-
36348978647
-
Selective pressures for and against genetic instability in cancer: a time-dependent problem
-
Komarova N.L., Sadovsky A.V., Wan F.Y. Selective pressures for and against genetic instability in cancer: a time-dependent problem. J R Soc Interface 2008, 5:105-121.
-
(2008)
J R Soc Interface
, vol.5
, pp. 105-121
-
-
Komarova, N.L.1
Sadovsky, A.V.2
Wan, F.Y.3
-
11
-
-
77950959834
-
-
Adaptation in natural and artificial systems. The University of Michigan;.
-
Holland JH. Adaptation in natural and artificial systems. The University of Michigan; 1975.
-
(1975)
-
-
Holland, J.H.1
-
13
-
-
77950934182
-
-
Genetic algorithms as function optimizers (doctoral dissertation). University of Michigan; .
-
Bethke AD. Genetic algorithms as function optimizers (doctoral dissertation). University of Michigan; 1980.
-
(1980)
-
-
Bethke, A.D.1
-
14
-
-
0348036427
-
Construction of higher-order deceptive functions using low-order Walsh coefficients
-
Goldberg D.E. Construction of higher-order deceptive functions using low-order Walsh coefficients. An Math Artif Intel 1992, 5:35-48.
-
(1992)
An Math Artif Intel
, vol.5
, pp. 35-48
-
-
Goldberg, D.E.1
-
16
-
-
33847237571
-
Darwinian medicine: a case for cancer
-
Greaves M. Darwinian medicine: a case for cancer. Nat Rev Cancer 2007, 7:213-221.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 213-221
-
-
Greaves, M.1
-
18
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
Wood L.D., Parsons D.W., Jones S., et al. The genomic landscapes of human breast and colorectal cancers. Science 2007, 318:1108-1113.
-
(2007)
Science
, vol.318
, pp. 1108-1113
-
-
Wood, L.D.1
Parsons, D.W.2
Jones, S.3
-
19
-
-
8144231084
-
Information dynamics in carcinogenesis and tumor growth
-
Gatenby R.A., Frieden B.R. Information dynamics in carcinogenesis and tumor growth. Mutat Res 2004, 568:259-273.
-
(2004)
Mutat Res
, vol.568
, pp. 259-273
-
-
Gatenby, R.A.1
Frieden, B.R.2
-
20
-
-
60649096136
-
Clonal diversity in the myeloproliferative neoplasms: independent origins of genetically distinct clones
-
Beer P.A., Jones A.V., Bench A.J., et al. Clonal diversity in the myeloproliferative neoplasms: independent origins of genetically distinct clones. Brit J Haematol 2009, 144:904-908.
-
(2009)
Brit J Haematol
, vol.144
, pp. 904-908
-
-
Beer, P.A.1
Jones, A.V.2
Bench, A.J.3
-
21
-
-
43649099401
-
Intratumor heterogeneity of epidermal growth factor receptor mutations in lung cancer and its correlation to the response to gefitinib
-
Taniguchi K., Okami J., Kodama K., Higashiyama M., Kato K. Intratumor heterogeneity of epidermal growth factor receptor mutations in lung cancer and its correlation to the response to gefitinib. Cancer Sci 2008, 99:929-935.
-
(2008)
Cancer Sci
, vol.99
, pp. 929-935
-
-
Taniguchi, K.1
Okami, J.2
Kodama, K.3
Higashiyama, M.4
Kato, K.5
-
22
-
-
33645396945
-
Genetic clonal diversity predicts progression to esophageal adenocarcinoma
-
Maley C.C., Galipeau P.C., Finley J.C., et al. Genetic clonal diversity predicts progression to esophageal adenocarcinoma. Nat Genet 2006, 38:468-473.
-
(2006)
Nat Genet
, vol.38
, pp. 468-473
-
-
Maley, C.C.1
Galipeau, P.C.2
Finley, J.C.3
-
23
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
Greenman C., Stephens P., Smith R., et al. Patterns of somatic mutation in human cancer genomes. Nature 2007, 446:153-158.
-
(2007)
Nature
, vol.446
, pp. 153-158
-
-
Greenman, C.1
Stephens, P.2
Smith, R.3
-
24
-
-
61449182121
-
Principles of cancer therapy: oncogene and non-oncogene addiction
-
Luo J., Solimini N.L., Elledge S.J. Principles of cancer therapy: oncogene and non-oncogene addiction. Cell 2009, 136:823-837.
-
(2009)
Cell
, vol.136
, pp. 823-837
-
-
Luo, J.1
Solimini, N.L.2
Elledge, S.J.3
-
25
-
-
67650376000
-
Genetic and epigenetic heterogeneity in cancer: a genome-centric perspective
-
Heng H.H.Q., Bremer S.W., Stevens J.B., Ye K.J., Liu G., Ye C.J. Genetic and epigenetic heterogeneity in cancer: a genome-centric perspective. J Cell Physiol 2009, 220:538-547.
-
(2009)
J Cell Physiol
, vol.220
, pp. 538-547
-
-
Heng, H.H.Q.1
Bremer, S.W.2
Stevens, J.B.3
Ye, K.J.4
Liu, G.5
Ye, C.J.6
-
26
-
-
0015133749
-
Self-organization of matter and the evolution of biological macromolecules
-
Eigen M. Self-organization of matter and the evolution of biological macromolecules. Naturwiss 1971, 58:465-523.
-
(1971)
Naturwiss
, vol.58
, pp. 465-523
-
-
Eigen, M.1
-
27
-
-
33244497405
-
Tradeoff between short-term and long-term adaptation in a changing environment
-
Forster R., Wilke C.O. Tradeoff between short-term and long-term adaptation in a changing environment. Phys Rev E 2005, 72:041922.
-
(2005)
Phys Rev E
, vol.72
, pp. 041922
-
-
Forster, R.1
Wilke, C.O.2
-
28
-
-
4143091655
-
Evolvability is a selectable trait
-
Earl D.J., Deem M.W. Evolvability is a selectable trait. Proc Natl Acad Sci USA 2004, 101:11531-11536.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 11531-11536
-
-
Earl, D.J.1
Deem, M.W.2
-
29
-
-
0032979190
-
Mutators, population size, adaptive landscape and the adaptation of asexual populations of bacteria
-
Tenaillon O., Toupance B., Nagard H.L., Taddei F., Godelle B. Mutators, population size, adaptive landscape and the adaptation of asexual populations of bacteria. Genetics 1999, 152:485-493.
-
(1999)
Genetics
, vol.152
, pp. 485-493
-
-
Tenaillon, O.1
Toupance, B.2
Nagard, H.L.3
Taddei, F.4
Godelle, B.5
-
30
-
-
47549116419
-
Phenotypic diversity as an adaptation to environmental uncertainty
-
Donaldson-Matasci M.C., Lachmann M., Bergstrom C.T. Phenotypic diversity as an adaptation to environmental uncertainty. Evol Ecol Res 2008, 10:493-515.
-
(2008)
Evol Ecol Res
, vol.10
, pp. 493-515
-
-
Donaldson-Matasci, M.C.1
Lachmann, M.2
Bergstrom, C.T.3
-
32
-
-
84956208612
-
Inverse problems - an introduction
-
Sabatier P.C. Inverse problems - an introduction. Inverse Probl 1985, 1:UL1.
-
(1985)
Inverse Probl
, vol.1
-
-
Sabatier, P.C.1
-
33
-
-
35448954854
-
Targeting the absence: homozygous dna deletions as immutable signposts for cancer therapy
-
Varshavsky A. Targeting the absence: homozygous dna deletions as immutable signposts for cancer therapy. Proc Nat Acad Sci USA 2008, 104:14935-14940.
-
(2008)
Proc Nat Acad Sci USA
, vol.104
, pp. 14935-14940
-
-
Varshavsky, A.1
-
34
-
-
66349131929
-
Telomerase structure paves the way for new cancer therapies
-
Skordalakes E. Telomerase structure paves the way for new cancer therapies. Future Oncol 2009, 5:163-167.
-
(2009)
Future Oncol
, vol.5
, pp. 163-167
-
-
Skordalakes, E.1
-
35
-
-
0018141482
-
Tumor heterogeneity and the biology of cancer invasion and metastasis
-
Fidler I.J. Tumor heterogeneity and the biology of cancer invasion and metastasis. Cancer Res 1978, 38:2651-2660.
-
(1978)
Cancer Res
, vol.38
, pp. 2651-2660
-
-
Fidler, I.J.1
-
37
-
-
0344010691
-
Tumour tactics
-
Kitano H. Tumour tactics. Nature 2003, 426:125.
-
(2003)
Nature
, vol.426
, pp. 125
-
-
Kitano, H.1
-
38
-
-
0037206022
-
Genetic heterogeneity of single disseminated tumour cells in minimal residual cancer
-
Klein C.A., Blankenstein T.J.F., Schmidt-Kittler O., Petronio M., Polzer B., Stoecklein N.H. Genetic heterogeneity of single disseminated tumour cells in minimal residual cancer. Lancet 2002, 360:683-689.
-
(2002)
Lancet
, vol.360
, pp. 683-689
-
-
Klein, C.A.1
Blankenstein, T.J.F.2
Schmidt-Kittler, O.3
Petronio, M.4
Polzer, B.5
Stoecklein, N.H.6
-
39
-
-
1842581858
-
An error catastrophe in cancer?
-
Sole R.V., Deisboeck T.S. An error catastrophe in cancer?. J Theor Biol 2004, 228:47-54.
-
(2004)
J Theor Biol
, vol.228
, pp. 47-54
-
-
Sole, R.V.1
Deisboeck, T.S.2
-
41
-
-
4043075127
-
Cancer prevention strategies that address the evolutionary dynamics of neoplastic cells: Simulating benign cell boosters and selection for chemosensitivity
-
Maley C.C., Reid B.J., Forrest S. Cancer prevention strategies that address the evolutionary dynamics of neoplastic cells: Simulating benign cell boosters and selection for chemosensitivity. Cancer Epidemiol Biomark Prev 2004, 13:1375-1384.
-
(2004)
Cancer Epidemiol Biomark Prev
, vol.13
, pp. 1375-1384
-
-
Maley, C.C.1
Reid, B.J.2
Forrest, S.3
-
42
-
-
0035913336
-
Evolution of digital organisms at high mutation rates leads to survival of the flattest
-
Wilke C.O., Wang J.L., Ofria C., Lenski R.E. Evolution of digital organisms at high mutation rates leads to survival of the flattest. Nature 2001, 412:331-333.
-
(2001)
Nature
, vol.412
, pp. 331-333
-
-
Wilke, C.O.1
Wang, J.L.2
Ofria, C.3
Lenski, R.E.4
-
43
-
-
8844279091
-
Destructive cycles: the role of genomic instability and adaptation in carcinogenesis
-
Schneider B.L., Kulesz-Martin M. Destructive cycles: the role of genomic instability and adaptation in carcinogenesis. Carcinogenesis 2004, 25:2033-2044.
-
(2004)
Carcinogenesis
, vol.25
, pp. 2033-2044
-
-
Schneider, B.L.1
Kulesz-Martin, M.2
-
44
-
-
85013312416
-
Tumor angiogenesis - therapeutic implications
-
Folkman J., Bach M., Rowe J.W., et al. Tumor angiogenesis - therapeutic implications. New Engl J Med 1971, 285:1182-1186.
-
(1971)
New Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
Bach, M.2
Rowe, J.W.3
-
45
-
-
47949099628
-
Modes of resistance to antiangiogenic therapy
-
Bergers G., Hanahan D. Modes of resistance to antiangiogenic therapy. Nat Rev Cancer 2008, 8:592-603.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
46
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Paez-Ribes M., Allen E., Hudock J., et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 2009, 15:220-231.
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Paez-Ribes, M.1
Allen, E.2
Hudock, J.3
-
47
-
-
60649087564
-
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
-
Ebos J.M.L., Lee C.R., Cruz-Munoz W., et al. Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell 2009, 15:232-239.
-
(2009)
Cancer Cell
, vol.15
, pp. 232-239
-
-
Ebos, J.M.L.1
Lee, C.R.2
Cruz-Munoz, W.3
-
48
-
-
52949141463
-
Accelerated evolution of resistance in multidrug environments
-
Hegreness M., Shoresh N., Damian D., Hartl D., Kishony R. Accelerated evolution of resistance in multidrug environments. Proc Nat Acad Sci USA 2008, 105:13977-13981.
-
(2008)
Proc Nat Acad Sci USA
, vol.105
, pp. 13977-13981
-
-
Hegreness, M.1
Shoresh, N.2
Damian, D.3
Hartl, D.4
Kishony, R.5
-
49
-
-
21744437791
-
Repopulation of cancer cells during therapy: an important cause of treatment failure
-
Kim J.J., Tannock I.F. Repopulation of cancer cells during therapy: an important cause of treatment failure. Nat Rev Cancer 2005, 5:516-525.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 516-525
-
-
Kim, J.J.1
Tannock, I.F.2
-
50
-
-
52049126703
-
The stochastic edge in adaptive evolution
-
Brunet E., Rouzine I.M., Wilke C.O. The stochastic edge in adaptive evolution. Genetics 2008, 179:603-620.
-
(2008)
Genetics
, vol.179
, pp. 603-620
-
-
Brunet, E.1
Rouzine, I.M.2
Wilke, C.O.3
-
51
-
-
52949144577
-
Natural selection fails to optimize mutation rates for long-term adaptation on rugged fitness landscapes
-
Clune J., Misevic D., Ofria C., Lenski R.E., Elena S.F., Sanjuan R. Natural selection fails to optimize mutation rates for long-term adaptation on rugged fitness landscapes. PLoS Comput Biol 2008, 4:e1000187.
-
(2008)
PLoS Comput Biol
, vol.4
-
-
Clune, J.1
Misevic, D.2
Ofria, C.3
Lenski, R.E.4
Elena, S.F.5
Sanjuan, R.6
-
52
-
-
0036853354
-
Optimal mutation rates in dynamic environments
-
Nilsson M., Snoad N. Optimal mutation rates in dynamic environments. Bull Math Biol 2002, 64:1033-1043.
-
(2002)
Bull Math Biol
, vol.64
, pp. 1033-1043
-
-
Nilsson, M.1
Snoad, N.2
-
53
-
-
0042242609
-
The evolution of mutator genes in bacterial populations: the roles of environmental change and timing
-
Tanaka M.M., Bergstrom C.T., Levin B.R. The evolution of mutator genes in bacterial populations: the roles of environmental change and timing. Genetics 2003, 164:843-854.
-
(2003)
Genetics
, vol.164
, pp. 843-854
-
-
Tanaka, M.M.1
Bergstrom, C.T.2
Levin, B.R.3
-
54
-
-
41049095398
-
Mutator dynamics in fluctuating environments
-
Travis J.M.J., Travis E.R. Mutator dynamics in fluctuating environments. Proc R Soc Lond B 2002, 269:591-597.
-
(2002)
Proc R Soc Lond B
, vol.269
, pp. 591-597
-
-
Travis, J.M.J.1
Travis, E.R.2
-
55
-
-
84901461202
-
-
Evolvability in dynamic fitness landscapes: a genetic algorithm approach. In: Proceedings of 1999 congress on evolutionary computation 2009. IEEE Press;
-
Grefenstette JJ. Evolvability in dynamic fitness landscapes: a genetic algorithm approach. In: Proceedings of 1999 congress on evolutionary computation 2009. IEEE Press; 1999, p. 2031-8.
-
(1999)
, pp. 2031-8
-
-
Grefenstette, J.J.1
-
56
-
-
70350336005
-
Cancer research meets evolutionary biology
-
Pepper J.W., Findlay C.S., Kassen R., Spencer S.L., Maley C.C. Cancer research meets evolutionary biology. Evol Appl 2009, 2:62-70.
-
(2009)
Evol Appl
, vol.2
, pp. 62-70
-
-
Pepper, J.W.1
Findlay, C.S.2
Kassen, R.3
Spencer, S.L.4
Maley, C.C.5
|