Metastasis: Inherent vs. acquired phenotype

Medical Hypotheses

Volumn 74, Issue 5, 2010, Pages 874-876

  Zhang, Li jun ^a   Li, Hang ^b   Zhang, Li ying ^b   Gu, Yu ^b   Song, Yue ^b   Li, Fanfan ^b   Jiang, Li na ^b   Li, Qing ^b   Zhang, Hui zhong ^a   Zhang, Feng ^b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HERMES ANTIGEN; MESSENGER RNA;

ARTICLE; CANCER STEM CELL; CELL HETEROGENEITY; CELL MIGRATION; CELL POPULATION; CELL SURVIVAL; HUMAN; MALIGNANT NEOPLASTIC DISEASE; METASTASIS; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PRIMARY TUMOR; TUMOR GROWTH;

CELL MOVEMENT; HUMANS; MODELS, BIOLOGICAL; NEOPLASM METASTASIS; NEOPLASTIC STEM CELLS;

EID: 77950927952     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2009.11.023     Document Type: Article

References (21)

1. Fearon E.R., Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990, 61:759-767.
2. Bernards R., Weinberg R.A. A progression puzzle. Nature 2002, 418:823.
3. Weinberg R.A. Mechanisms of malignant progression. Carcinogenesis 2008, 29:1092-1095.
4. Hunter K.W., Crawford N.P., Alsarraj J. Mechanisms of metastasis. Breast Cancer Res 2008, 10:S2.
5. Fidler I.J., Kripke M.L. Metastasis results from preexisting variant cells within a malignant tumor. Science 1977, 197:893-895.
6. Wicha M.S., Liu S., Dontu G. Cancer stem cells: an old idea; a paradigm shift. Cancer Res 2006, 66:1883-1890.
7. Laird D.J., von Andrian U.H., Wagers A.J. Stem cell trafficking in tissue development, growth, and disease. Cell 2008, 132:612-630.
8. Shi Q., Rafii S., Wu M.H., Wijelath E.S., Yu C., Ishida A., Hammond W.P., et al. Evidence for circulating bone marrow-derived endothelial cells. Blood 1998, 92:362-367.
9. Kuznetsov S.A., Mankani M.H., Gronthos S., Satomura K., Bianco P., Robey P.G. Circulating skeletal stem cells. J Cell Biol 2001, 153:1133-1140.
10. Ratajczak M.Z., Kucia M., Reca R., Majka M., Janowska-Wieczorek A., Ratajczak J. Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells 'hide out' in the bone marrow. Leukemia 2004, 18:29-40.
11. Podsypanina K., Du Y.C., Jechlinger M., Beverly L.J., Hambardzumyan D., Varmus H. Seeding and propagation of untransformed mouse mammary cells in the lung. Science 2008, 321:1841-1844.
12. Hüsemann Y., Geigl J.B., Schubert F., Musiani P., Meyer M., Burghart E., Klein C.A., et al. Systemic spread is an early step in breast cancer. Cancer Cell 2008, 13:58-68.
13. Schmidt-Kittler O., Ragg T., Daskalakis A., Granzow M., Ahr A., Blankenstein T.J., Klein C.A., et al. From latent disseminated cells to overt metastasis: genetic analysis of systemic breast cancer progression. Proc Natl Acad Sci USA. 2003, 100:7737-7742.
14. Klarmann G.J., Hurt E.M., Mathews L.A., Zhang X., Duhagon M.A., Mistree T., Farrar W.L., et al. Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature. Clin Exp Metastasis 2009, 26:433-446.
15. Balic M., Lin H., Young L., Hawes D., Giuliano A., McNamara G., Cote R.J., et al. Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype. Clin Cancer Res 2006, 12:5615-5621.
16. Pandit T.S., Kennette W., Mackenzie L., Zhang G., Al-Katib W., Andrews J., Tuck A.B., et al. Lymphatic metastasis of breast cancer cells is associated with differential gene expression profiles that predict cancer stem cell-like properties and the ability to survive, establish and grow in a foreign environment. Int J Oncol 2009, 35:297-308.
17. Hermann P.C., Huber S.L., Herrler T., Aicher A., Ellwart J.W., Guba M., Heeschen C., et al. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 2007, 1:313-323.
18. Kucia M., Reca R., Miekus K., Wanzeck J., Wojakowski W., Janowska-Wieczorek A., Ratajczak M.Z., et al. Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis. Stem Cells 2005, 23:879-894.
19. Boccaccio C., Comoglio P.M. Invasive growth: a MET-driven genetic programme for cancer and stem cells. Nat Rev Cancer 2006, 6:637-645.
20. Polyak K., Weinberg R.A. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 2009, 9:265-273.
21. Luzzi K.J., MacDonald I.C., Schmidt E.E., Kerkvliet N., Morris V.L., Chambers A.F., Groom A.C. Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases. Am J Pathol 1998, 153:865-873.