메뉴 건너뛰기




Volumn 58, Issue 6, 2010, Pages 741-754

Glutamine synthetase deficiency in murine astrocytes results in neonatal death

Author keywords

Alanine; Astrocytes; Brain; Conditional gene inactivation; Glutamate; Glutamine; Glycine; Mouse

Indexed keywords

ALANINE; AMINO ACID; AMMONIA; COMPLEMENTARY DNA; GLUCOSE; GLUTAMATE AMMONIA LIGASE; GLUTAMIC ACID; GLUTAMINE; GLYCINE; LACTIC ACID; MESSENGER RNA; RNA 18S;

EID: 77950903826     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20960     Document Type: Article
Times cited : (53)

References (59)
  • 1
    • 0032518360 scopus 로고    scopus 로고
    • Roles of neuroactive amino acids in ammonia neurotoxicity
    • DOI 10.1002/(SICI)1097-4547(19980115)51:2<133::AID-JNR1>3.0.CO;2-E
    • Albrecht J. 1998. Roles of neuroactive amino acids in ammonia neurotoxicity. J Neurosci Res 51:133-138. (Pubitemid 28073020)
    • (1998) Journal of Neuroscience Research , vol.51 , Issue.2 , pp. 133-138
    • Albrecht, J.1
  • 3
    • 0036293742 scopus 로고    scopus 로고
    • Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation
    • DOI 10.1128/MCB.22.14.5100-5113.2002
    • Bajenaru ML, Zhu Y, Hedrick NM, Donahoe J, Parada LF, Gutmann DH. 2002. Astrocyte-specific inactivation of the neurofibromatosis 1 gene (Nfl) is insufficient for astrocytoma formation. Mol Cell Biol 22:5100-5113. (Pubitemid 34700701)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.14 , pp. 5100-5113
    • Bajenaru, M.L.1    Zhu, Y.2    Hedrick, N.M.3    Donahoe, J.4    Parada, L.F.5    Gutmann, D.H.6
  • 4
    • 0036096020 scopus 로고    scopus 로고
    • Loss of expression of glial fibrillary acidic protein in acute hyperammonemia
    • DOI 10.1016/S0197-0186(02)00037-2, PII S0197018602000372
    • Belanger M, Desjardins P, Chatauret N, Butterworth RF. 2002. Loss of expression of glial fibrillary acidic protein in acute hyperammonemia. Neurochem Int 41:155-160. (Pubitemid 34521688)
    • (2002) Neurochemistry International , vol.41 , Issue.2-3 , pp. 155-160
    • Belanger, M.1    Desjardins, P.2    Chatauret, N.3    Butterworth, R.F.4
  • 5
    • 60449098799 scopus 로고    scopus 로고
    • Identifying the direct effects of ammonia on the brain
    • Bosoi CR, Rose CF. 2009. Identifying the direct effects of ammonia on the brain. Metab Brain Dis 24:95-102.
    • (2009) Metab Brain Dis , vol.24 , pp. 95-102
    • Bosoi, C.R.1    Rose, C.F.2
  • 7
    • 0020433282 scopus 로고
    • Glutamine synthetase activity during mouse brain development
    • DOI 10.1007/BF01959739
    • Caldani M, Rolland B, Fages C, Tardy M. 1982. Glutamine synthetase activity during mouse brain development. Experientia 38:1199-1202. (Pubitemid 13200497)
    • (1982) Experientia , vol.38 , Issue.10 , pp. 1199-1202
    • Caldani, M.1    Rolland, B.2    Fages, C.3    Tardy, M.4
  • 8
    • 0025191416 scopus 로고
    • Glutamine synthetase in the central nervous system is not confined to astrocytes
    • DOI 10.1016/0165-5728(90)90088-5
    • Cammer W. 1990. Glutamine synthetase in the central nervous system is not confined to astrocytes. J Neuroimmunol 26:173-178. (Pubitemid 20023724)
    • (1990) Journal of Neuroimmunology , vol.26 , Issue.2 , pp. 173-178
    • Cammer, W.1
  • 9
    • 0037193463 scopus 로고    scopus 로고
    • The glutamine commute: Take the N line and transfer to the A
    • Chaudry FA, Reimer RJ, Edwards RH. 2002. The glutamine commute: Take the N line and transfer to the A. J Cell Biol 157:349-355.
    • (2002) J Cell Biol , vol.157 , pp. 349-355
    • Chaudry, F.A.1    Reimer, R.J.2    Edwards, R.H.3
  • 10
    • 0025041953 scopus 로고
    • Glutamine synthetase immunoreactivity is present in oligodendroglia of various regions of the central nervous system
    • D'Amelio F, Eng LF, Gibbs MA. 1990. Glutamine synthetase immunoreactivity is present in oligodendroglia of various regions of the central nervous system. Glia 3:335-341.
    • (1990) Glia , vol.3 , pp. 335-341
    • D'Amelio, F.1    Eng, L.F.2    Gibbs, M.A.3
  • 11
    • 0023858963 scopus 로고
    • Glutamine synthetase: A marker of an astroglial subpopulation in primary cultures of defined brain areas
    • Fages C, Khelil M, Rolland B, Bridoux AM, Tardy M. 1988. Glutamine synthetase: A marker of an astroglial subpopulation in primary cultures of defined brain areas. Dev Neurosci 10:47-56. (Pubitemid 18078839)
    • (1988) Developmental Neuroscience , vol.10 , Issue.1 , pp. 47-56
    • Fages, C.1    Khelil, M.2    Rolland, B.3    Bridoux, A.M.4    Tardy, M.5
  • 12
    • 0036629585 scopus 로고    scopus 로고
    • Neurobiology of ammonia
    • Felipo V. 2002. Neurobiology of ammonia. Prog Neurobiol 67:259-279.
    • (2002) Prog Neurobiol , vol.67 , pp. 259-279
    • Felipo, V.1
  • 16
    • 0025874776 scopus 로고
    • Hyperammonemia does not impair brain function in the absence of net glutamine synthesis
    • Hawkins RA, Jessy J. 1991. Hyperammonemia does not impair brain function in the absence of net glutamine synthesis. Biochem J 277:697-703.
    • (1991) Biochem J , vol.277 , pp. 697-703
    • Hawkins, R.A.1    Jessy, J.2
  • 18
    • 0027198896 scopus 로고
    • The effect of 4 days methionine sulfoximine administration on net muscle protein breakdown in rats
    • DOI 10.1016/0261-5614(93)90078-I
    • Heeneman S, Deutz NEP. 1993. The effect of 4 days methionine sulfoximine administration on net muscle protein breakdown in rats. Clin Nutr 12:182-190. (Pubitemid 23213447)
    • (1993) Clinical Nutrition , vol.12 , Issue.3 , pp. 182-190
    • Heeneman, S.1    Deutz, N.E.P.2
  • 19
    • 7544241660 scopus 로고    scopus 로고
    • Development of neurotransmitter systems during critical periods
    • DOI 10.1016/j.expneurol.2004.03.027, PII S001448860400130X
    • Herlenius E, Lagercrantz H. 2004. Development of neurotransmitter systems during critical periods. Exp Neurol 190:S8-S21. (Pubitemid 39451785)
    • (2004) Experimental Neurology , vol.190 , Issue.SUPPL. 1
    • Herlenius, E.1    Lagercrantz, H.2
  • 20
    • 2442546861 scopus 로고    scopus 로고
    • Intercellular metabolic compartmentation in the brain: Past, present and future
    • DOI 10.1016/j.neuint.2003.08.016, PII S0197018603002936
    • Hertz L. 2004. Intercellular metabolic compartmentation in the brain: Past, present and future. Neurochem Int 45:285-296. (Pubitemid 38625620)
    • (2004) Neurochemistry International , vol.45 , Issue.2-3 , pp. 285-296
    • Hertz, L.1
  • 21
    • 35448998940 scopus 로고    scopus 로고
    • Energy metabolism in brain cells: Effects of elevated ammonia concentrations
    • DOI 10.1007/s11011-007-9068-z
    • Hertz L, Kala G. 2007. Energy metabolism in brain cells: Effects of elevated ammonia concentrations. Metab Brain Dis 22:199-218. (Pubitemid 47624320)
    • (2007) Metabolic Brain Disease , vol.22 , Issue.3-4 , pp. 199-218
    • Hertz, L.1    Kala, G.2
  • 24
    • 20844451123 scopus 로고    scopus 로고
    • AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
    • DOI 10.1016/j.cmet.2004.12.003, PII S1550413104000099
    • Kahn BB, Alquier T, Carling D, Hardie DG. 2005. AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 1:15-25. (Pubitemid 43960587)
    • (2005) Cell Metabolism , vol.1 , Issue.1 , pp. 15-25
    • Kahn, B.B.1    Alquier, T.2    Carling, D.3    Hardie, D.G.4
  • 25
    • 0029788778 scopus 로고    scopus 로고
    • Severity of hyperammonemic encephalopathy correlates with brain ammonia level and saturation of glutamine synthetase in vivo
    • Kanamori K, Ross BD, Chung JC, Kuo EL. 1996. Severity of hyperammonemic encephalopathy correlates with brain ammonia level and saturation of glutamine synthetase in vivo. J Neurochem 67:1584-1594. (Pubitemid 26314216)
    • (1996) Journal of Neurochemistry , vol.67 , Issue.4 , pp. 1584-1594
    • Kanamori, K.1    Ross, B.D.2    Chung, J.C.3    Kuo, E.L.4
  • 27
    • 27744534016 scopus 로고    scopus 로고
    • NMDA receptors mediate feeding elicited by neuropeptide Y in the lateral and perifornical hypothalamus
    • Lee SW, Stanley BG. 2005. NMDA receptors mediate feeding elicited by neuropeptide Y in the lateral and perifornical hypothalamus. Brain Res 1063:1-8.
    • (2005) Brain Res , vol.1063 , pp. 1-8
    • Lee, S.W.1    Stanley, B.G.2
  • 28
    • 0036667911 scopus 로고    scopus 로고
    • Sensitivity and accuracy of quantitative real-time polymerase chain reaction using SYBR green I depends on cDNA synthesis conditions
    • Lekanne dit Deprez RH, Fijnvandraat AC, Ruijter JM, Moorman AFM. 2002. Sensitivity and accuracy of quantitative real-time polymerase chain reaction using SYBR green I depends on cDNA synthesis conditions. Anal Biochem 307:63-69.
    • (2002) Anal Biochem , vol.307 , pp. 63-69
    • Lekanne Dit Deprez, R.H.1    Fijnvandraat, A.C.2    Ruijter, J.M.3    Moorman, A.F.M.4
  • 29
    • 0028173680 scopus 로고
    • Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice
    • DOI 10.1016/0092-8674(94)90108-2
    • Li Y, Erzurumlu RS, Chen C, Jhaveri S, Tonegawa S. 1994. Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice. Cell 76:427-437. (Pubitemid 24064165)
    • (1994) Cell , vol.76 , Issue.3 , pp. 427-437
    • Li, Y.1    Erzurumlu, R.S.2    Chen, C.3    Jhaveri, S.4    Tonegawa, S.5
  • 32
    • 10044257458 scopus 로고    scopus 로고
    • Glutamate and GABA receptor signalling in the developing brain
    • DOI 10.1016/j.neuroscience.2004.09.042, PII S0306452204008723
    • Lujan R, Shigemoto R, Lopez-Bendito G. 2005. Glutamate and GABA receptor signalling in the developing brain. Neuroscience 130:567-580. (Pubitemid 39601430)
    • (2005) Neuroscience , vol.130 , Issue.3 , pp. 567-580
    • Lujan, R.1    Shigemoto, R.2    Lopez-Bendito, G.3
  • 33
    • 1242317638 scopus 로고    scopus 로고
    • Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family
    • DOI 10.1007/s00424-003-1117-9, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
    • Mackenzie B, Erickson JD. 2004. Sodium-coupled neutral aminoacid (system N/A) transporters of the SLC38 gene family. Pflug Arch Eur J Phys 447:784-795. (Pubitemid 38241468)
    • (2004) Pflugers Archiv European Journal of Physiology , vol.447 , Issue.5 , pp. 784-795
    • Mackenzie, B.1    Erickson, J.D.2
  • 35
    • 35848947733 scopus 로고    scopus 로고
    • The glutamate-glutamine cycle is not stoichiometric; fates of glutamate in brain
    • McKenna MC. 2007. The glutamate-glutamine cycle is not stoichiometric; fates of glutamate in brain. J Neurosci Res 85:3347-3358.
    • (2007) J Neurosci Res , vol.85 , pp. 3347-3358
    • McKenna, M.C.1
  • 36
    • 0024468835 scopus 로고
    • The ontogeny and localization of glutamine synthetase gene expression in rat brain
    • DOI 10.1016/0169-328X(89)90068-5
    • Mearow KM, Mill JF, Vitkovic L. 1989. The ontogeny and localization of glutamine synthetase gene expession in rat brain. Mol Brain Res 6:223-232. (Pubitemid 19283308)
    • (1989) Molecular Brain Research , vol.6 , Issue.4 , pp. 223-232
    • Mearow, K.M.1    Mill, J.F.2    Vitkovic, L.3
  • 37
    • 0026669238 scopus 로고
    • Glutamine synthetase immunoreactivity in two types of mouse brain glial cells
    • Miyake T, Kitamura T. 1992. Glutamine synthetase immunoreactivity in two types of mouse brain glial cells. Brain Res 586:53-60.
    • (1992) Brain Res , vol.586 , pp. 53-60
    • Miyake, T.1    Kitamura, T.2
  • 38
    • 0028343648 scopus 로고
    • Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
    • DOI 10.1016/0896-6273(94)90210-0
    • Monyer H, Burnashev N, Laurie DJ, Sakmann B, Seeburg PH. 1994. Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12:529-540. (Pubitemid 24100885)
    • (1994) Neuron , vol.12 , Issue.3 , pp. 529-540
    • Monyer, H.1    Burnashev, N.2    Laurie, D.J.3    Sakmann, B.4    Seeburg, P.H.5
  • 39
    • 0018776955 scopus 로고
    • The distribution of glutamine synthetase in the rat central nervous system
    • Norenberg MD. 1979. The distribution of glutamine synthetase in the rat central nervous system. J Histochem Cytochem 3:756-762. (Pubitemid 9187420)
    • (1979) Journal of Histochemistry and Cytochemistry , vol.27 , Issue.3 , pp. 756-762
    • Norenberg, M.D.1
  • 40
    • 0027432836 scopus 로고
    • Distribution of glial fibrillary acidic protein and glutamine synthetase in human cerebral cortical astrocytes - A light and electron microscopic study
    • DOI 10.1007/BF01186359
    • Ong WY, Garey LJ, Reynolds R. 1993. Distribution of glial fibrillary acidicprotein and glutamine synthetase in human cerebral cortical astrocytes - A light and electron microscopic study. J Neurocytol 22:893-902. (Pubitemid 23312101)
    • (1993) Journal of Neurocytology , vol.22 , Issue.10 , pp. 893-902
    • Ong, W.Y.1    Garey, L.J.2    Reynolds, R.3
  • 41
    • 0020322662 scopus 로고
    • The activities in different neural cell types of certain enzymes associated with the metabolic compartmentation glutamate
    • DOI 10.1016/0165-3806(82)90091-8
    • Patel AJ, Hunt A, Gordon RD, Balázs R. 1982. The activities in different neural cell types of certain enzymes associated with the metabolic compartmentation glutamate. Dev Brain Res 4:3-11. (Pubitemid 12062960)
    • (1982) Developmental Brain Research , vol.4 , Issue.1 , pp. 3-11
    • Patel, A.J.1    Hunt, A.2    Gordon, R.D.3    Balazs, R.4
  • 42
    • 0032814037 scopus 로고    scopus 로고
    • The subependymal layer in rodents: A site of structural plasticity and cell migration in the adult mammalian brain
    • DOI 10.1016/S0361-9230(99)00037-4, PII S0361923099000374
    • Peretto P, Merighi A, Fasolo A, Bonfanti L. 1999. The subenpendymal layer in rodents: A site of structural plasticity and cell migration in the adult mammalian brain. Brain Res Bull 49:221-243. (Pubitemid 29328556)
    • (1999) Brain Research Bulletin , vol.49 , Issue.4 , pp. 221-243
    • Peretto, P.1    Merighi, A.2    Fasolo, A.3    Bonfanti, L.4
  • 45
    • 0032531738 scopus 로고    scopus 로고
    • Patterns of status epilepticus-induced neuronal injury during development and long-term consequences
    • Sankar R, Shin DH, Liu H, Mazarati A, Pereira de Vasconcelos A, Wasterlain CG. 1998. Patterns of status epilepticus-induced neuronal injury during development and long-term consequences. J Neurosci 18:8382-8393. (Pubitemid 28465013)
    • (1998) Journal of Neuroscience , vol.18 , Issue.20 , pp. 8382-8393
    • Sankar, R.1    Shin, D.H.2    Liu, H.3    Mazarati, A.4    De Vasconcelos, A.P.5    Wasterlain, C.G.6
  • 47
    • 0030901162 scopus 로고    scopus 로고
    • Fluoro-Jade: A novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration
    • DOI 10.1016/S0006-8993(96)01387-X, PII S000689939601387X
    • Schmued L, Albertson C, Slikker W. 1997. Fluoro-jade; a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res 751:37-46. (Pubitemid 27122134)
    • (1997) Brain Research , vol.751 , Issue.1 , pp. 37-46
    • Schmued, L.C.1    Albertson, C.2    Slikker Jr., W.3
  • 48
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain [1]
    • DOI 10.1038/5007
    • Soriano P. 1999. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 21:70-71. (Pubitemid 29036285)
    • (1999) Nature Genetics , vol.21 , Issue.1 , pp. 70-71
    • Soriano, P.1
  • 49
    • 0025958468 scopus 로고
    • Glutamine synthetase in oligodendrocytes and astrocytes: New biochemical and immunocytochemical evidence
    • Tansey FA, Farooq M, Cammer W. 1991. Glutamine synthetase in oligodendrocytes and astrocytes: New biochemical and immunocytchemical evidence. J Neurochem 56:266-272. (Pubitemid 21901959)
    • (1991) Journal of Neurochemistry , vol.56 , Issue.1 , pp. 266-272
    • Tansey, F.A.1    Farooq, M.2    Cammer, W.3
  • 50
    • 0027761052 scopus 로고
    • The biochemistry and toxicology of benzoic acid metabolism and its relationship to the elimination of waste nitrogen
    • Tremblay GC, Qureshi IA. 1993. The biochemistry and toxicology of benzoic acid metabolism and its relationship to the elimination of waste nitrogen. Pharmacol Ther 60:63-90.
    • (1993) Pharmacol Ther , vol.60 , pp. 63-90
    • Tremblay, G.C.1    Qureshi, I.A.2
  • 54
    • 0033868095 scopus 로고    scopus 로고
    • Controversy surrounding the existence of discrete functional classes of astrocytes in adult gray matter
    • DOI 10.1002/1098-1136(200008)31:2<95::AID-GLIA10>3.0.CO;2-6
    • Walz W. 2000. Controversy surrounding the existence of discrete functional classes of astrocytes in adult gray matter. Glia 31:95-103. (Pubitemid 30617177)
    • (2000) GLIA , vol.31 , Issue.2 , pp. 95-103
    • Walz, W.1
  • 55
    • 32544446451 scopus 로고    scopus 로고
    • Coping with stress: ElF2 kinases and translational control
    • Wek RC, Jiang HY, Anthony TG. 2006. Coping with stress: elF2 kinases and translational control. Biochem Soc Trans 34:7-11.
    • (2006) Biochem Soc Trans , vol.34 , pp. 7-11
    • Wek, R.C.1    Jiang, H.Y.2    Anthony, T.G.3
  • 56
    • 33845787470 scopus 로고    scopus 로고
    • Heat-induced antigen retrieval: Mechanisms and application to histochemistry
    • DOI 10.1016/j.proghi.2006.09.001, PII S0079633606000611
    • Yamashita S. 2007. Heat-induced antigen retrieval: Mechanisms and application to histochemistry. Prog Histochem Cytochem 41:141-200. (Pubitemid 46013929)
    • (2007) Progress in Histochemistry and Cytochemistry , vol.41 , Issue.3 , pp. 141-200
    • Yamashita, S.1
  • 57
    • 0035170704 scopus 로고    scopus 로고
    • HGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo
    • DOI 10.1002/gene.10008
    • Zhuo L, Theis M, Alvarez-Maya I, Brenner M, Willecke K, Messing A. 2001. hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo. Genesis 31:85-94. (Pubitemid 33064319)
    • (2001) Genesis , vol.31 , Issue.2 , pp. 85-94
    • Zhuo, L.1    Theis, M.2    Alvarez-Maya, I.3    Brenner, M.4    Willecke, K.5    Messing, A.6
  • 58
    • 35448961690 scopus 로고    scopus 로고
    • The anaplerotic flux and ammonia detoxification in hepatic encephalopathy
    • DOI 10.1007/s11011-007-9069-y
    • Zwingmann C. 2007. The anaplerotic flux and ammonia detoxification in hepatic encephalopathy. Metab Brain Dis 22:235-249. (Pubitemid 47624321)
    • (2007) Metabolic Brain Disease , vol.22 , Issue.3-4 , pp. 235-249
    • Zwingmann, C.1
  • 59
    • 0346888682 scopus 로고    scopus 로고
    • 13C-NMR
    • Zwingmann C, Leibfritz D. 2003. Regulation of glial metabolism studied by 13C-NMR. NMR Biomed 16:370-399. (Pubitemid 38008364)
    • (2003) NMR in Biomedicine , vol.16 , Issue.6-7 , pp. 370-399
    • Zwingmann, C.1    Leibfritz, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.