메뉴 건너뛰기




Volumn 22, Issue 3-4, 2007, Pages 321-335

NMDA receptors in hyperammonemia and hepatic encephalopathy

Author keywords

Ammonia toxicity; Cognitive impairment; Hepatic encephalopathy; Hyperammonemia; Neurological alterations; NMDA receptors

Indexed keywords

AMMONIA; CYCLIC GMP; DIZOCILPINE; GLUTAMATE AMMONIA LIGASE; GLUTAMIC ACID; KETAMINE; METHIONINE SULFOXIMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N(G) NITROARGININE; NITRIC OXIDE; PHOSPHODIESTERASE INHIBITOR; SILDENAFIL; ZAPRINAST;

EID: 35449006358     PISSN: 08857490     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11011-007-9067-0     Document Type: Conference Paper
Times cited : (66)

References (49)
  • 1
    • 0342470611 scopus 로고    scopus 로고
    • Chronic moderate hyperammonemia impairs active and passive avoidance behavior and conditional discrimination learning in rats
    • Aguilar MA, Miñarro J, Felipo V (2000) Chronic moderate hyperammonemia impairs active and passive avoidance behavior and conditional discrimination learning in rats. Exp Neurol 161:704-713
    • (2000) Exp Neurol , vol.161 , pp. 704-713
    • Aguilar, M.A.1    Miñarro, J.2    Felipo, V.3
  • 2
    • 0034957318 scopus 로고    scopus 로고
    • Glutamine as a pathogenic factor in hepatic encephalopathy
    • Albrecht J, Dolinska M (2001) Glutamine as a pathogenic factor in hepatic encephalopathy. J Neurosci Res 65:1-5
    • (2001) J Neurosci Res , vol.65 , pp. 1-5
    • Albrecht, J.1    Dolinska, M.2
  • 4
    • 0029926167 scopus 로고    scopus 로고
    • Hippocampal cGMP and cAMP are differentially involved in memory processing of inhibitory avoidance learning
    • Bernabeu R, Scmitz P, Faillace MP, Izquierdo I, Medina JM (1996) Hippocampal cGMP and cAMP are differentially involved in memory processing of inhibitory avoidance learning. Neuroreport 7:585-588
    • (1996) Neuroreport , vol.7 , pp. 585-588
    • Bernabeu, R.1    Scmitz, P.2    Faillace, M.P.3    Izquierdo, I.4    Medina, J.M.5
  • 5
    • 0030758721 scopus 로고    scopus 로고
    • Further evidence for the involvement of a hippocampal cGMP/cGMP-dependent protein kinase cascade in memory consolidation
    • Bernabeu R, Schroder N, Quevedo J, Cammarota M, Izquierdo I, Medina JH (1997) Further evidence for the involvement of a hippocampal cGMP/cGMP-dependent protein kinase cascade in memory consolidation. Neuroreport 8:2221-2224
    • (1997) Neuroreport , vol.8 , pp. 2221-2224
    • Bernabeu, R.1    Schroder, N.2    Quevedo, J.3    Cammarota, M.4    Izquierdo, I.5    Medina, J.H.6
  • 7
    • 0030899194 scopus 로고    scopus 로고
    • Memory-related changes of nitric oxide synthase activity and nitrite level in rat brain
    • Chen J, Zhang S, Zuo P, Tang L (1997) Memory-related changes of nitric oxide synthase activity and nitrite level in rat brain. Neuroreport 8:1771-1774
    • (1997) Neuroreport , vol.8 , pp. 1771-1774
    • Chen, J.1    Zhang, S.2    Zuo, P.3    Tang, L.4
  • 8
    • 0036829813 scopus 로고    scopus 로고
    • Region selective alterations of soluble guanylate cyclase content and modulation in brain of cirrhotic patients
    • Corbalan R, Chatauret N, Behrends S, Butterworth RF, Felipo V (2002) Region selective alterations of soluble guanylate cyclase content and modulation in brain of cirrhotic patients. Hepatology 36:1155-1162
    • (2002) Hepatology , vol.36 , pp. 1155-1162
    • Corbalan, R.1    Chatauret, N.2    Behrends, S.3    Butterworth, R.F.4    Felipo, V.5
  • 9
    • 0028821928 scopus 로고
    • Modulation of learning processes by ionotropic glutamate receptor ligands
    • Danysz W, Zajaczkowski W, Parsons CG (1995). Modulation of learning processes by ionotropic glutamate receptor ligands. Behav Pharmacol 6:455-474
    • (1995) Behav Pharmacol , vol.6 , pp. 455-474
    • Danysz, W.1    Zajaczkowski, W.2    Parsons, C.G.3
  • 10
    • 12844262177 scopus 로고    scopus 로고
    • Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts
    • Erceg S, Monfort P, Hernández-Viadel M, Rodrigo R, Montoliu C, Felipo V (2005a) Oral administration of sildenafil restores learning ability in rats with hyperammonemia and with portacaval shunts. Hepatology 41:299-306
    • (2005) Hepatology , vol.41 , pp. 299-306
    • Erceg, S.1    Monfort, P.2    Hernández-Viadel, M.3    Rodrigo, R.4    Montoliu, C.5    Felipo, V.6
  • 11
    • 13844296393 scopus 로고    scopus 로고
    • Restoration of learning ability in hyperammonemic rats by increasing extracellular cGMP in brain
    • Erceg S, Monfort P, Hernandez-Viadel M, Llansola M, Montoliu C, Felipo V (2005b) Restoration of learning ability in hyperammonemic rats by increasing extracellular cGMP in brain. Brain Res 1036:115-121
    • (2005) Brain Res , vol.1036 , pp. 115-121
    • Erceg, S.1    Monfort, P.2    Hernandez-Viadel, M.3    Llansola, M.4    Montoliu, C.5    Felipo, V.6
  • 12
    • 0028038955 scopus 로고
    • Effects of apomorphine and L-methionine-sulfoximine on the release of excitatory amino acid neurotransmitters and glutamine in the striatum of the conscious rat
    • Exposito I, Sanz B, Porras A, Mora F (1994) Effects of apomorphine and L-methionine-sulfoximine on the release of excitatory amino acid neurotransmitters and glutamine in the striatum of the conscious rat. Eur J Neurosci 6:287-291
    • (1994) Eur J Neurosci , vol.6 , pp. 287-291
    • Exposito, I.1    Sanz, B.2    Porras, A.3    Mora, F.4
  • 13
    • 0023711180 scopus 로고
    • Long term ingestion of ammonium increases acetylglutamate and urea levels without affecting the amount of carbamyl phosphate synthase
    • Felipo V, Miñana MD, Grisolía S (1988) Long term ingestion of ammonium increases acetylglutamate and urea levels without affecting the amount of carbamyl phosphate synthase. Eur J Biochem 176:567-571
    • (1988) Eur J Biochem , vol.176 , pp. 567-571
    • Felipo, V.1    Miñana, M.D.2    Grisolía, S.3
  • 14
    • 0027232160 scopus 로고
    • Ammonium injection induces an N-methyl-D-aspartate receptor-mediated proteolysis of the microtubule-associated protein MAP-2
    • Felipo V, Grau E, Miñana MD, Grisolía S (1993) Ammonium injection induces an N-methyl-D-aspartate receptor-mediated proteolysis of the microtubule-associated protein MAP-2. J Neurochem 60:1626-1630
    • (1993) J Neurochem , vol.60 , pp. 1626-1630
    • Felipo, V.1    Grau, E.2    Miñana, M.D.3    Grisolía, S.4
  • 16
    • 0025874776 scopus 로고
    • Hyperammonemia does not impair brain function in the absence of net glutamine synthesis
    • Hawkins RA, Jessy J (1991). Hyperammonemia does not impair brain function in the absence of net glutamine synthesis. Biochem J 277:697-703
    • (1991) Biochem J , vol.277 , pp. 697-703
    • Hawkins, R.A.1    Jessy, J.2
  • 17
    • 0015787774 scopus 로고
    • The acute action of ammonia on rat brain metabolism in vivo
    • Hawkins RA, Miller AL, Nielsen RC, Veech RL (1973) The acute action of ammonia on rat brain metabolism in vivo. Biochem J 134:1001-1008
    • (1973) Biochem J , vol.134 , pp. 1001-1008
    • Hawkins, R.A.1    Miller, A.L.2    Nielsen, R.C.3    Veech, R.L.4
  • 18
    • 0027474144 scopus 로고
    • Effect of reducing brain glutamine synthesis on metabolic symptoms of hepatic encephalopathy
    • Hawkins RA, Jessy J, Mans AM, DeJoseph R (1993) Effect of reducing brain glutamine synthesis on metabolic symptoms of hepatic encephalopathy. J Neurochem 60:1000-1006
    • (1993) J Neurochem , vol.60 , pp. 1000-1006
    • Hawkins, R.A.1    Jessy, J.2    Mans, A.M.3    Dejoseph, R.4
  • 20
    • 0032430914 scopus 로고    scopus 로고
    • Chronic hyperammonemia impairs glutamate-nitric oxide-cyclic GMP pathway in cerebellar neurons in culture and in the rat in vivo
    • Hermenegildo C, Montoliu C, Llansola M, Muñoz MD, Gaztelu JM, Miñana MD, Felipo V (1998) Chronic hyperammonemia impairs glutamate-nitric oxide-cyclic GMP pathway in cerebellar neurons in culture and in the rat in vivo. Eur J Neurosci 10:3201-3209
    • (1998) Eur J Neurosci , vol.10 , pp. 3201-3209
    • Hermenegildo, C.1    Montoliu, C.2    Llansola, M.3    Muñoz, M.D.4    Gaztelu, J.M.5    Miñana, M.D.6    Felipo, V.7
  • 21
    • 0033993867 scopus 로고    scopus 로고
    • Activation of NMDA receptors in rat brain in vivo following acute ammonia intoxication. Characterization by in vivo brain microdialysis
    • Hermenegildo C, Monfort P, Felipo V (2000) Activation of NMDA receptors in rat brain in vivo following acute ammonia intoxication. Characterization by in vivo brain microdialysis. Hepatology 31:709-715
    • (2000) Hepatology , vol.31 , pp. 709-715
    • Hermenegildo, C.1    Monfort, P.2    Felipo, V.3
  • 22
    • 0015146399 scopus 로고
    • Cerebral effects of acute ammonia intoxication
    • Hindfelt B, Siesjo BK (1971) Cerebral effects of acute ammonia intoxication. Scand J Clin Lab Invest 28:365-374
    • (1971) Scand J Clin Lab Invest , vol.28 , pp. 365-374
    • Hindfelt, B.1    Siesjo, B.K.2
  • 23
    • 0017362424 scopus 로고
    • Effect of acute ammonia intoxication on cerebral metabolism in rats with portacaval shunts
    • Hindfelt B, Plum F, Duffy TE (1977) Effect of acute ammonia intoxication on cerebral metabolism in rats with portacaval shunts. J Clin Invest 59:386-396
    • (1977) J Clin Invest , vol.59 , pp. 386-396
    • Hindfelt, B.1    Plum, F.2    Duffy, T.E.3
  • 24
    • 0027500453 scopus 로고
    • Chronic hyperammonemia prevents changes in brain energy and ammonia metabolites induced by acute ammonia intoxication
    • Kosenko E, Kaminsky YG, Felipo V, Minana M-D, Grisolia S (1993) Chronic hyperammonemia prevents changes in brain energy and ammonia metabolites induced by acute ammonia intoxication. Biochim Biophys Acta 1180:321-326
    • (1993) Biochim Biophys Acta , vol.1180 , pp. 321-326
    • Kosenko, E.1    Kaminsky, Y.G.2    Felipo, V.3    Minana, M.-D.4    Grisolia, S.5
  • 25
    • 0027988722 scopus 로고
    • Brain ATP depletion induced by acute ammonia intoxication in rats is mediated by activation of the NMDA receptor and of Na/K-ATPase
    • Kosenko E, Kaminsky Y, Grau E, Miñana MD, Marcaida G, Grisolía S, Felipo V (1994) Brain ATP depletion induced by acute ammonia intoxication in rats is mediated by activation of the NMDA receptor and of Na/K-ATPase. J Neurochem 63:2172-2178
    • (1994) J Neurochem , vol.63 , pp. 2172-2178
    • Kosenko, E.1    Kaminsky, Y.2    Grau, E.3    Miñana, M.D.4    Marcaida, G.5    Grisolía, S.6    Felipo, V.7
  • 26
    • 0029023214 scopus 로고
    • Nitroarginine, an inhibitor of nitric oxide synthetase, attenuates ammonia toxicity and ammonia-induced alterations in brain metabolism
    • Kosenko E, Kaminsky Y, Grau E, Miñana MD, Grisolía S, Felipo V (1995) Nitroarginine, an inhibitor of nitric oxide synthetase, attenuates ammonia toxicity and ammonia-induced alterations in brain metabolism. Neurochem Res 20:451-456
    • (1995) Neurochem Res , vol.20 , pp. 451-456
    • Kosenko, E.1    Kaminsky, Y.2    Grau, E.3    Miñana, M.D.4    Grisolía, S.5    Felipo, V.6
  • 27
    • 0030901009 scopus 로고    scopus 로고
    • Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria
    • Kosenko E, Felipo V, Montoliu C, Grisolia S, Kaminsky Y (1996) Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria. Metab Brain Dis 12:69-82
    • (1996) Metab Brain Dis , vol.12 , pp. 69-82
    • Kosenko, E.1    Felipo, V.2    Montoliu, C.3    Grisolia, S.4    Kaminsky, Y.5
  • 28
    • 0030901009 scopus 로고    scopus 로고
    • Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria
    • Kosenko E, Felipo V, Montoliu C, Grisolía S, Kaminsky Y (1997a) Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria. Metab Brain Dis 12:69-82
    • (1997) Metab Brain Dis , vol.12 , pp. 69-82
    • Kosenko, E.1    Felipo, V.2    Montoliu, C.3    Grisolía, S.4    Kaminsky, Y.5
  • 30
    • 0031949404 scopus 로고    scopus 로고
    • Nitroarginine, an inhibitor of nitric oxide synthase, prevents changes in superoxide radical and antioxidant enzymes induced by ammonia intoxication
    • Kosenko E, Kaminsky Y, Lopata O, Muravyov N, Kaminsky A, Hermenegildo C, Felipo V (1998) Nitroarginine, an inhibitor of nitric oxide synthase, prevents changes in superoxide radical and antioxidant enzymes induced by ammonia intoxication. Metab Brain Dis 13:29-41
    • (1998) Metab Brain Dis , vol.13 , pp. 29-41
    • Kosenko, E.1    Kaminsky, Y.2    Lopata, O.3    Muravyov, N.4    Kaminsky, A.5    Hermenegildo, C.6    Felipo, V.7
  • 31
    • 0032967196 scopus 로고    scopus 로고
    • Blocking NMDA receptors prevents the oxidative stress induced by acute ammonia intoxication
    • Kosenko E, Kaminski Y, Lopata O, Muravyov N, Felipo V (1999) Blocking NMDA receptors prevents the oxidative stress induced by acute ammonia intoxication. Free Radic Biol Med 26:1369-1374
    • (1999) Free Radic Biol Med , vol.26 , pp. 1369-1374
    • Kosenko, E.1    Kaminski, Y.2    Lopata, O.3    Muravyov, N.4    Felipo, V.5
  • 32
    • 0034644823 scopus 로고    scopus 로고
    • Alteration of mitochondrial calcium homeostasis by ammonia-induced activation of NMDA receptors in rat brain in vivo
    • Kosenko E, Kaminsky Y, Stavroskaya IG, Felipo V (2000) Alteration of mitochondrial calcium homeostasis by ammonia-induced activation of NMDA receptors in rat brain in vivo. Brain Res 880:139-146
    • (2000) Brain Res , vol.880 , pp. 139-146
    • Kosenko, E.1    Kaminsky, Y.2    Stavroskaya, I.G.3    Felipo, V.4
  • 36
    • 0031962873 scopus 로고    scopus 로고
    • Combined stimulation of the glycine and polyamine sites of the NMDA receptor attenuates NMDA blockade-induced learning deficits of rats in a 14-unit-T-maze
    • Meyer RC, Knox J, Purwin DA, Spangler EL, Ingram DK (1998) Combined stimulation of the glycine and polyamine sites of the NMDA receptor attenuates NMDA blockade-induced learning deficits of rats in a 14-unit-T-maze. Psychopharmacology 135:290-295
    • (1998) Psychopharmacology , vol.135 , pp. 290-295
    • Meyer, R.C.1    Knox, J.2    Purwin, D.A.3    Spangler, E.L.4    Ingram, D.K.5
  • 38
    • 0344765458 scopus 로고    scopus 로고
    • Nicotine prevents glutamate-induced proteolysis of the microtubule-associated protein MAP-2 and glutamate neurotoxicity in primary cultures of cerebellar neurons
    • Miñana MD, Montoliu C, Llansola M, Grisolía S, Felipo V (1998) Nicotine prevents glutamate-induced proteolysis of the microtubule-associated protein MAP-2 and glutamate neurotoxicity in primary cultures of cerebellar neurons. Neuropharmacology 37:847-857
    • (1998) Neuropharmacology , vol.37 , pp. 847-857
    • Miñana, M.D.1    Montoliu, C.2    Llansola, M.3    Grisolía, S.4    Felipo, V.5
  • 39
    • 0035799999 scopus 로고    scopus 로고
    • Altered content and modulation of soluble guanylate cyclase in the cerebellum of rats with portacaval anastomosis
    • Monfort P, Corbalán R, Martinez L, López-Talavera JC, Córdoba J, Felipo V (2001) Altered content and modulation of soluble guanylate cyclase in the cerebellum of rats with portacaval anastomosis. Neuroscience 104:1127-1139
    • (2001) Neuroscience , vol.104 , pp. 1127-1139
    • Monfort, P.1    Corbalán, R.2    Martinez, L.3    López-Talavera, J.C.4    Córdoba, J.5    Felipo, V.6
  • 40
    • 0036981248 scopus 로고    scopus 로고
    • Effects of hyperammonemia and liver disease on glutamatergic neurotransmission
    • Monfort P, Muñoz MD, ElAyadi A, Kosenko E, Felipo V (2002) Effects of hyperammonemia and liver disease on glutamatergic neurotransmission. Metab Brain Dis 17:67-86
    • (2002) Metab Brain Dis , vol.17 , pp. 67-86
    • Monfort, P.1    Muñoz, M.D.2    Elayadi, A.3    Kosenko, E.4    Felipo, V.5
  • 43
    • 0024375476 scopus 로고
    • +-evoked release of transmitter amino acids investigated by microdialysis
    • +-evoked release of transmitter amino acids investigated by microdialysis. J Neurochem 52:1823-1829
    • (1989) J Neurochem , vol.52 , pp. 1823-1829
    • Paulsen, R.E.1    Fonnum, F.2
  • 44
    • 0030688947 scopus 로고    scopus 로고
    • Possible role of nitric oxide-cyclic GMP pathway in object recognition memory: Effects of 7-nitroindazole and zaprinast
    • Prickaerts J, Steinbusch HW, Smits JF, et al. (1997) Possible role of nitric oxide-cyclic GMP pathway in object recognition memory: effects of 7-nitroindazole and zaprinast. Eur J Pharmacol 337:125-136
    • (1997) Eur J Pharmacol , vol.337 , pp. 125-136
    • Prickaerts, J.1    Steinbusch, H.W.2    Smits, J.F.3
  • 45
    • 0036468327 scopus 로고    scopus 로고
    • CGMP, but not cAMP, in rat hippocampus is involved in early stages of object memory consolidation
    • Prickaerts J, De vente J, Ong W, et al. (2002) cGMP, but not cAMP, in rat hippocampus is involved in early stages of object memory consolidation. Eur J Pharmacol 436:83-87
    • (2002) Eur J Pharmacol , vol.436 , pp. 83-87
    • Prickaerts, J.1    De Vente, J.2    Ong, W.3
  • 47
    • 0034722592 scopus 로고    scopus 로고
    • A novel nitrate ester reverses the cognitive impairment caused by scopolamine in the Morris water maze
    • Smith S, Dringenberg HC, Bennett BM, et al. (2000) A novel nitrate ester reverses the cognitive impairment caused by scopolamine in the Morris water maze. Neuroreport 11:3883-3886
    • (2000) Neuroreport , vol.11 , pp. 3883-3886
    • Smith, S.1    Dringenberg, H.C.2    Bennett, B.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.