IL-18 inhibits TNF-α-induced osteoclastogenesis possibly via a T cell-independent mechanism in synergy with IL-12 in vivo

Calcified Tissue International

Volumn 86, Issue 3, 2010, Pages 242-248

  Morita, Yukiko ^a   Kitaura, Hideki ^b   Yoshimatsu, Masako ^a   Fujimura, Yuji ^a   Kohara, Haruka ^a   Eguchi, Toshiko ^a   Yoshida, Noriaki ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

IL 12; IL 18; Osteoclast; TNF

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 12; INTERLEUKIN 12 RECEPTOR; INTERLEUKIN 18; INTERLEUKIN 18 RECEPTOR; MESSENGER RNA; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CALVARIA; CELL COUNT; CELL CULTURE; CONTROLLED STUDY; IN VIVO STUDY; INHIBITION KINETICS; MALE; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T CELL DEPLETION; T LYMPHOCYTE;

ANIMALS; BONE REMODELING; BONE RESORPTION; CELL COUNT; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; INTERLEUKIN-12; INTERLEUKIN-18; MALE; MICE; MICE, INBRED C57BL; OSTEOCLASTS; RECEPTORS, INTERLEUKIN-12; RECEPTORS, INTERLEUKIN-18; RNA, MESSENGER; STEM CELLS; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 77950863280     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-010-9335-6     Document Type: Article

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