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Volumn 251, Issue 4, 2010, Pages 692-700

Inchinkoto, an herbal medicine, exerts beneficial effects in the rat liver under stress with hepatic ischemia-reperfusion and subsequent hepatectomy

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GENIPIN; INCHINKOTO; INDUCIBLE NITRIC OXIDE SYNTHASE; LIVER PROTECTIVE AGENT; UNCLASSIFIED DRUG;

EID: 77950862080     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0b013e3181d50299     Document Type: Article
Times cited : (33)

References (52)
  • 1
    • 0032240594 scopus 로고    scopus 로고
    • Mechanisms of reperfusion injury after warm ischemia of the liver
    • Jaeschke H. Mechanisms of reperfusion injury after warm ischemia of the liver. J Hepatobiliary Pancreat Surg. 1998;5:402-408.
    • (1998) J Hepatobiliary Pancreat Surg , vol.5 , pp. 402-408
    • Jaeschke, H.1
  • 2
    • 0032974013 scopus 로고    scopus 로고
    • Prevention of Kupffer cell-induced oxidant injury in rat liver by atrial natriuretic peptide
    • Bilzer M, Jaeschke H, Vollmar AM, et al. Prevention of Kupffer cell-induced oxidant injury in rat liver by atrial natriuretic peptide. Am J Physiol. 1999; 276:G1137-G1144.
    • (1999) Am J Physiol , vol.276
    • Bilzer, M.1    Jaeschke, H.2    Vollmar, A.M.3
  • 3
    • 11144318582 scopus 로고    scopus 로고
    • Free radical scavenger (edaravone) prevents endotoxin-induced liver injury after partial hepatectomy in rats
    • DOI 10.1016/j.jhep.2004.09.018, PII S0168827804004349
    • Tsuji K, Kwon AH, Yoshida H, et al. Free radical scavenger (edaravone) prevents endotoxin-induced liver injury after partial hepatectomy in rats. J Hepatol. 2005;42:94-101. (Pubitemid 40038906)
    • (2005) Journal of Hepatology , vol.42 , Issue.1 , pp. 94-101
    • Tsuji, K.1    Kwon, A.-H.2    Yoshida, H.3    Qiu, Z.4    Kaibori, M.5    Okumura, T.6    Kamiyama, Y.7
  • 4
    • 26044452361 scopus 로고    scopus 로고
    • MCI-186 (edaravone), a free radical scavenger, attenuates hepatic warm ischemia-reperfusion injury in rats
    • Suzuki F, Hashikura Y, Ise H, et al. MCI-186 (edaravone), a free radical scavenger, attenuates hepatic warm ischemia-reperfusion injury in rats. Transpl Int. 2005;18:844-853.
    • (2005) Transpl Int , vol.18 , pp. 844-853
    • Suzuki, F.1    Hashikura, Y.2    Ise, H.3
  • 5
    • 0036125604 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase inhibition attenuates ischemia-reperfusion injury of the rat liver
    • Kobayashi M, Takeyoshi I, Yoshinari D, et al. P38 mitogen-activated protein kinase inhibition attenuates ischemia-reperfusion injury of the rat liver. Surgery. 2002;131:344-349.
    • (2002) Surgery , vol.131 , pp. 344-349
    • Kobayashi, M.1    Takeyoshi, I.2    Yoshinari, D.3
  • 6
    • 0026021473 scopus 로고
    • Effects of cytokines on the liver
    • Andus T, Bauer J, Gerok W. Effects of cytokines on the liver. Hepatology. 1991;13:364-375.
    • (1991) Hepatology , vol.13 , pp. 364-375
    • Andus, T.1    Bauer, J.2    Gerok, W.3
  • 7
    • 0030797334 scopus 로고    scopus 로고
    • Ischemia/reperfusion-induced microvascular dysfunction: Role of oxidants and lipid mediators
    • Kurose I, Argenbright LW, Wolf R, et al. Ischemia/reperfusion-induced microvascular dysfunction: role of oxidants and lipid mediators. Am J Physiol. 1997;272:H2976-H2982.
    • (1997) Am J Physiol , vol.272
    • Kurose, I.1    Argenbright, L.W.2    Wolf, R.3
  • 8
    • 0023256645 scopus 로고
    • Conversion of xanthine dehydrogenase to oxidase in ischemic rat tissues
    • Engerson TD, McKelvey TG, Rhyne DB, et al. Conversion of xanthine dehydrogenase to oxidase in ischemic rat tissues. J Clin Invest. 1987;79: 1564-1570.
    • (1987) J Clin Invest , vol.79 , pp. 1564-1570
    • Engerson, T.D.1    McKelvey, T.G.2    Rhyne, D.B.3
  • 9
    • 33644631485 scopus 로고    scopus 로고
    • Therapeutic effects of xanthine oxidase inhibitors: Renaissance half a century after the discovery of allopurinol
    • Pacher P, Nivorozhkin A, Szabo C. Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol. Pharmacol Rev. 2006;58:87-114.
    • (2006) Pharmacol Rev , vol.58 , pp. 87-114
    • Pacher, P.1    Nivorozhkin, A.2    Szabo, C.3
  • 10
    • 0028910314 scopus 로고
    • Endotoxin-stimulated nitric oxide production increases injury and reduces rat liver chemiluminescence during reperfusion
    • Ma TT, Ischiropoulos H, Brass CA. Endotoxin-stimulated nitric oxide production increases injury and reduces rat liver chemiluminescence during reperfusion. Gastroenterology. 1995;108:463-469.
    • (1995) Gastroenterology , vol.108 , pp. 463-469
    • Ma, T.T.1    Ischiropoulos, H.2    Brass, C.A.3
  • 11
    • 33846863589 scopus 로고    scopus 로고
    • Nitric oxide and peroxynitrite in health and disease
    • Pacher P, Beckman JS, Liaudet L. Nitric oxide and peroxynitrite in health and disease. Physiol Rev. 2007;87:315-424.
    • (2007) Physiol Rev , vol.87 , pp. 315-424
    • Pacher, P.1    Beckman, J.S.2    Liaudet, L.3
  • 12
    • 0031005579 scopus 로고    scopus 로고
    • Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein ki-nases
    • Bradham CA, Stachlewitz RF, Gao W, et al. Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein ki-nases. Hepatology. 1997;25:1128-1135.
    • (1997) Hepatology , vol.25 , pp. 1128-1135
    • Bradham, C.A.1    Stachlewitz, R.F.2    Gao, W.3
  • 13
    • 18844414517 scopus 로고    scopus 로고
    • JNK mediates hepatic ischemia reperfusion injury
    • Uehara T, Bennett B, Sakata ST, et al. JNK mediates hepatic ischemia reperfusion injury. J Hepatol. 2005;42:850-859.
    • (2005) J Hepatol , vol.42 , pp. 850-859
    • Uehara, T.1    Bennett, B.2    Sakata, S.T.3
  • 14
    • 33646497683 scopus 로고    scopus 로고
    • Heat shock proteins and mitogen-activated protein kinases in steatotic livers undergoing ischemia-reperfusion: Some answers
    • Massip-Salcedo M, Casillas-Ramirez A, Franco-Gou R, et al. Heat shock proteins and mitogen-activated protein kinases in steatotic livers undergoing ischemia-reperfusion: some answers. Am J Pathol. 2006;168:1474-1485.
    • (2006) Am J Pathol , vol.168 , pp. 1474-1485
    • Massip-Salcedo, M.1    Casillas-Ramirez, A.2    Franco-Gou, R.3
  • 15
    • 33746379603 scopus 로고    scopus 로고
    • JNK-and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells
    • Kim BJ, Ryu SW, Song BJ. JNK-and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells. J Biol Chem. 2006;281:21256-21265.
    • (2006) J Biol Chem , vol.281 , pp. 21256-21265
    • Kim, B.J.1    Ryu, S.W.2    Song, B.J.3
  • 16
    • 0033973569 scopus 로고    scopus 로고
    • Genipin, a metabolite derived from the herbal medicine Inchin-ko-to, and suppression of Fas-induced lethal liver apoptosis in mice
    • Yamamoto M, Miura N, Ohtake N, et al. Genipin, a metabolite derived from the herbal medicine Inchin-ko-to, and suppression of Fas-induced lethal liver apoptosis in mice. Gastroenterology. 2000;118:380-389.
    • (2000) Gastroenterology , vol.118 , pp. 380-389
    • Yamamoto, M.1    Miura, N.2    Ohtake, N.3
  • 17
    • 0029968187 scopus 로고    scopus 로고
    • The herbal medicine Inchin-ko-to inhibits liver cell apoptosis induced by transforming growth factor beta 1
    • Yamamoto M, Ogawa K, Morita M, et al. The herbal medicine Inchin-ko-to inhibits liver cell apoptosis induced by transforming growth factor beta 1. Hepatology. 1996;23:552-559.
    • (1996) Hepatology , vol.23 , pp. 552-559
    • Yamamoto, M.1    Ogawa, K.2    Morita, M.3
  • 18
    • 0034946710 scopus 로고    scopus 로고
    • Beneficial effect of a traditional herbal medicine (inchin-ko-to) in postoperative biliary atresia patients
    • Kobayashi H, Horikoshi K, Yamataka A, et al. Beneficial effect of a traditional herbal medicine (inchin-ko-to) in postoperative biliary atresia patients. Pediatr Surg Int. 2001;17:386-389.
    • (2001) Pediatr Surg Int , vol.17 , pp. 386-389
    • Kobayashi, H.1    Horikoshi, K.2    Yamataka, A.3
  • 19
    • 11144358423 scopus 로고    scopus 로고
    • Genipin enhances Mrp2 (Abcc2)-mediated bile formation and organic anion transport in rat liver
    • Shoda J, Miura T, Utsunomiya H, et al. Genipin enhances Mrp2 (Abcc2)-mediated bile formation and organic anion transport in rat liver. Hepatology. 2004;39:167-178.
    • (2004) Hepatology , vol.39 , pp. 167-178
    • Shoda, J.1    Miura, T.2    Utsunomiya, H.3
  • 20
    • 69249212587 scopus 로고    scopus 로고
    • Choleretic effect of inchinkoto, a herbal medicine, on livers of patients with biliary obstruction due to bile duct carcinoma
    • Watanabe S, Yokoyama Y, Oda K, et al. Choleretic effect of inchinkoto, a herbal medicine, on livers of patients with biliary obstruction due to bile duct carcinoma. Hepatol Res. 2009;39:247-255.
    • (2009) Hepatol Res , vol.39 , pp. 247-255
    • Watanabe, S.1    Yokoyama, Y.2    Oda, K.3
  • 21
    • 34347377398 scopus 로고    scopus 로고
    • Inchinkoto, a herbal medicine, and its ingredients dually exert Mrp2/MRP2-mediated choleresis and Nrf2-mediated antioxidative action in rat livers
    • Okada K, Shoda J, Kano M, et al. Inchinkoto, a herbal medicine, and its ingredients dually exert Mrp2/MRP2-mediated choleresis and Nrf2-mediated antioxidative action in rat livers. Am J Physiol Gastrointest Liver Physiol. 2007;292:G1450-G1463.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Okada, K.1    Shoda, J.2    Kano, M.3
  • 22
    • 33847014110 scopus 로고    scopus 로고
    • Does estrogen contribute to the hepatic regeneration following portal branch ligation in rats?
    • Kawai T, Yokoyama Y, Kawai S, et al. Does estrogen contribute to the hepatic regeneration following portal branch ligation in rats? Am J Physiol Gastrointest Liver Physiol. 2007;292:G582-G589.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Kawai, T.1    Yokoyama, Y.2    Kawai, S.3
  • 23
    • 0037424429 scopus 로고    scopus 로고
    • Lack of tyrosine nitration by hypochlo-rous acid in the presence of physiological concentrations of nitrite. Implications for the role of nitryl chloride in tyrosine nitration in vivo
    • Whiteman M, Siau JL, Halliwell B. Lack of tyrosine nitration by hypochlo-rous acid in the presence of physiological concentrations of nitrite. Implications for the role of nitryl chloride in tyrosine nitration in vivo. J Biol Chem. 2003;278:8380-8384.
    • (2003) J Biol Chem , vol.278 , pp. 8380-8384
    • Whiteman, M.1    Siau, J.L.2    Halliwell, B.3
  • 24
    • 42749091401 scopus 로고    scopus 로고
    • MEK inhibitor enhances the inhibitory effect of imatinib on pancreatic cancer cell growth
    • Takayama Y, Kokuryo T, Yokoyama Y, et al. MEK inhibitor enhances the inhibitory effect of imatinib on pancreatic cancer cell growth. Cancer Lett. 2008;264:241-249.
    • (2008) Cancer Lett , vol.264 , pp. 241-249
    • Takayama, Y.1    Kokuryo, T.2    Yokoyama, Y.3
  • 25
    • 0026611673 scopus 로고
    • IL-6 and NF-IL6 in acute-phase response and viral infection
    • Akira S, Kishimoto T. IL-6 and NF-IL6 in acute-phase response and viral infection. Immunol Rev. 1992;127:25-50.
    • (1992) Immunol Rev , vol.127 , pp. 25-50
    • Akira, S.1    Kishimoto, T.2
  • 26
    • 4143151617 scopus 로고    scopus 로고
    • Arginine pathways and the inflammatory response: Interregulation of nitric oxide and polyamines: Review article
    • Satriano J. Arginine pathways and the inflammatory response: interregulation of nitric oxide and polyamines: review article. Amino Acids. 2004;26:321-329.
    • (2004) Amino Acids , vol.26 , pp. 321-329
    • Satriano, J.1
  • 27
    • 0030662094 scopus 로고    scopus 로고
    • Nitric oxide and inflammatory arthritides
    • Miyasaka N, Hirata Y. Nitric oxide and inflammatory arthritides. Life Sci. 1997;61:2073-2081.
    • (1997) Life Sci , vol.61 , pp. 2073-2081
    • Miyasaka, N.1    Hirata, Y.2
  • 28
    • 47049085675 scopus 로고    scopus 로고
    • Tumoricidal activity of endothelium-derived NO and the survival of metastatic cells with high GSH and Bcl-2 levels
    • Ortega A, Carretero J, Obrador E, et al. Tumoricidal activity of endothelium-derived NO and the survival of metastatic cells with high GSH and Bcl-2 levels. Nitric Oxide. 2008;19:107-114.
    • (2008) Nitric Oxide , vol.19 , pp. 107-114
    • Ortega, A.1    Carretero, J.2    Obrador, E.3
  • 30
    • 0033546733 scopus 로고    scopus 로고
    • Hepatic ischemia/reperfusion in rats induces iNOS gene transcription by activation of NF-kappaB
    • Hur GM, Ryu YS, Yun HY, et al. Hepatic ischemia/reperfusion in rats induces iNOS gene transcription by activation of NF-kappaB. Biochem Biophys Res Commun. 1999;261:917-922.
    • (1999) Biochem Biophys Res Commun , vol.261 , pp. 917-922
    • Hur, G.M.1    Ryu, Y.S.2    Yun, H.Y.3
  • 31
    • 0028559399 scopus 로고
    • Enzymic studies on the animal and intestinal bacterial metabolism of geniposide
    • Akao T, Kobashi K, Aburada M. Enzymic studies on the animal and intestinal bacterial metabolism of geniposide. Biol Pharm Bull. 1994;17:1573-1576.
    • (1994) Biol Pharm Bull , vol.17 , pp. 1573-1576
    • Akao, T.1    Kobashi, K.2    Aburada, M.3
  • 32
    • 0028605318 scopus 로고
    • A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
    • Lee JC, Laydon JT, McDonnell PC, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature. 1994;372:739-746.
    • (1994) Nature , vol.372 , pp. 739-746
    • Lee, J.C.1    Laydon, J.T.2    McDonnell, P.C.3
  • 33
    • 33745092105 scopus 로고    scopus 로고
    • Involvement of protein kinase B and mitogen-activated protein kinases in experimental normothermic liver isch-aemia-reperfusion injury
    • Cursio R, Filippa N, Miele C, et al. Involvement of protein kinase B and mitogen-activated protein kinases in experimental normothermic liver isch-aemia-reperfusion injury. Br J Surg. 2006;93:752-761.
    • (2006) Br J Surg , vol.93 , pp. 752-761
    • Cursio, R.1    Filippa, N.2    Miele, C.3
  • 34
    • 0033853801 scopus 로고    scopus 로고
    • Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury
    • Lentsch AB, Kato A, Yoshidome H, et al. Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury. Hepatology. 2000;32:169-173. (Pubitemid 30614647)
    • (2000) Hepatology , vol.32 , Issue.2 , pp. 169-173
    • Lentsch, A.B.1    Kato, A.2    Yoshidome, H.3    McMasters, K.M.4    Edwards, M.J.5
  • 35
    • 18044385349 scopus 로고    scopus 로고
    • Lipid peroxidation during ischemia depends on ischemia time in warm ischemia and reperfusion of rat liver
    • Fukai M, Hayashi T, Yokota R, et al. Lipid peroxidation during ischemia depends on ischemia time in warm ischemia and reperfusion of rat liver. Free Radic Biol Med. 2005;38:1372-1381.
    • (2005) Free Radic Biol Med , vol.38 , pp. 1372-1381
    • Fukai, M.1    Hayashi, T.2    Yokota, R.3
  • 36
    • 0037093483 scopus 로고    scopus 로고
    • A novel inhibitor of inducible nitric oxide synthase (ONO-1714) prevents critical warm ischemia-reperfu-sion injury in the pig liver
    • Meguro M, Katsuramaki T, Nagayama M, et al. A novel inhibitor of inducible nitric oxide synthase (ONO-1714) prevents critical warm ischemia-reperfu-sion injury in the pig liver. Transplantation. 2002;73:1439-1446.
    • (2002) Transplantation , vol.73 , pp. 1439-1446
    • Meguro, M.1    Katsuramaki, T.2    Nagayama, M.3
  • 37
    • 0036623149 scopus 로고    scopus 로고
    • Regulation of cyclooxygenase-2 by nitric oxide in activated hepatic macrophages during acute endotoxemia
    • Ahmad N, Chen LC, Gordon MA, et al. Regulation of cyclooxygenase-2 by nitric oxide in activated hepatic macrophages during acute endotoxemia. J Leukoc Biol. 2002;71:1005-1011.
    • (2002) J Leukoc Biol , vol.71 , pp. 1005-1011
    • Ahmad, N.1    Chen, L.C.2    Gordon, M.A.3
  • 38
    • 0033998103 scopus 로고    scopus 로고
    • Calcium-channel blocker attenuates Kupffer cell production of cytokine-induced neutrophil chemoattractant following ischemia-reperfusion in rat liver
    • Liang J, Yamaguchi Y, Matsumura F, et al. Calcium-channel blocker attenuates Kupffer cell production of cytokine-induced neutrophil chemoattractant following ischemia-reperfusion in rat liver. Dig Dis Sci. 2000;45:201-209.
    • (2000) Dig Dis Sci , vol.45 , pp. 201-209
    • Liang, J.1    Yamaguchi, Y.2    Matsumura, F.3
  • 41
    • 0025066123 scopus 로고
    • Multiple cytokines are required to induce hepatocyte nitric oxide production and inhibit total protein synthesis
    • Curran RD, Billiar TR, Stuehr DJ, et al. Multiple cytokines are required to induce hepatocyte nitric oxide production and inhibit total protein synthesis. Ann Surg. 1990;212:462-469.
    • (1990) Ann Surg , vol.212 , pp. 462-469
    • Curran, R.D.1    Billiar, T.R.2    Stuehr, D.J.3
  • 42
    • 0026734847 scopus 로고
    • Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin
    • Nussler AK, Di Silvio M, Billiar TR, et al. Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin. J Exp Med. 1992;176:261-264.
    • (1992) J Exp Med , vol.176 , pp. 261-264
    • Nussler, A.K.1    Di Silvio, M.2    Billiar, T.R.3
  • 43
    • 0028972555 scopus 로고
    • A central role for IL-1 beta in the in vitro and in vivo regulation of hepatic inducible nitric oxide synthase. IL-1 beta induces hepatic nitric oxide synthesis
    • Geller DA, de Vera ME, Russell DA, et al. A central role for IL-1 beta in the in vitro and in vivo regulation of hepatic inducible nitric oxide synthase. IL-1 beta induces hepatic nitric oxide synthesis. J Immunol. 1995;155:4890-4898.
    • (1995) J Immunol , vol.155 , pp. 4890-4898
    • Geller, D.A.1    De Vera, M.E.2    Russell, D.A.3
  • 44
    • 33745851908 scopus 로고    scopus 로고
    • Mechanisms of interleukin-6 protection against ischemia-reperfusion injury in rat liver
    • Tiberio L, Tiberio GA, Bardella L, et al. Mechanisms of interleukin-6 protection against ischemia-reperfusion injury in rat liver. Cytokine. 2006;34: 131-142.
    • (2006) Cytokine , vol.34 , pp. 131-142
    • Tiberio, L.1    Tiberio, G.A.2    Bardella, L.3
  • 45
    • 0020633994 scopus 로고
    • Role of oxygen-derived free radicals in digestive tract diseases
    • Parks DA, Bulkley GB, Granger DN. Role of oxygen-derived free radicals in digestive tract diseases. Surgery. 1983;94:415-422.
    • (1983) Surgery , vol.94 , pp. 415-422
    • Parks, D.A.1    Bulkley, G.B.2    Granger, D.N.3
  • 46
    • 0035082637 scopus 로고    scopus 로고
    • Subcellular site of superoxide dismutase expression differentially controls AP-1 activity and injury in mouse liver following ischemia/reperfusion
    • Zhou W, Zhang Y, Hosch MS, et al. Subcellular site of superoxide dismutase expression differentially controls AP-1 activity and injury in mouse liver following ischemia/reperfusion. Hepatology. 2001;33:902-914.
    • (2001) Hepatology , vol.33 , pp. 902-914
    • Zhou, W.1    Zhang, Y.2    Hosch, M.S.3
  • 47
    • 0028007172 scopus 로고
    • Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury
    • Haddad IY, Pataki G, Hu P, et al. Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury. J Clin Invest. 1994;94:2407-2413.
    • (1994) J Clin Invest , vol.94 , pp. 2407-2413
    • Haddad, I.Y.1    Pataki, G.2    Hu, P.3
  • 48
    • 0033778872 scopus 로고    scopus 로고
    • Lipid peroxidation and peroxynitrite in retinal ischemia-reperfusion injury
    • Shibuki H, Katai N, Yodoi J, et al. Lipid peroxidation and peroxynitrite in retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci. 2000;41: 3607-3614.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 3607-3614
    • Shibuki, H.1    Katai, N.2    Yodoi, J.3
  • 49
    • 0033852205 scopus 로고    scopus 로고
    • Peroxynitrite-induced apoptosis involves activation of multiple caspases in HL-60 cells
    • Zhuang S, Simon G. Peroxynitrite-induced apoptosis involves activation of multiple caspases in HL-60 cells. Am J Physiol Cell Physiol. 2000;279:C341-C351.
    • (2000) Am J Physiol Cell Physiol , vol.279
    • Zhuang, S.1    Simon, G.2
  • 50
    • 33645893751 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase prevents hepatic, but not pulmonary, injury following isch-emia-reperfusion of rat liver
    • Takamatsu Y, Shimada K, Yamaguchi K, et al. Inhibition of inducible nitric oxide synthase prevents hepatic, but not pulmonary, injury following isch-emia-reperfusion of rat liver. Dig Dis Sci. 2006;51:571-579.
    • (2006) Dig Dis Sci , vol.51 , pp. 571-579
    • Takamatsu, Y.1    Shimada, K.2    Yamaguchi, K.3
  • 51
    • 1542781600 scopus 로고    scopus 로고
    • A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR
    • Huang W, Zhang J, Moore DD. A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR. J Clin Invest. 2004;113:137-143.
    • (2004) J Clin Invest , vol.113 , pp. 137-143
    • Huang, W.1    Zhang, J.2    Moore, D.D.3
  • 52
    • 0032801123 scopus 로고    scopus 로고
    • Protective effects of capillarisin on tert-butylhydroperoxide-induced oxidative damage in rat primary hepato-cytes
    • Chu CY, Tseng TH, Hwang JM, et al. Protective effects of capillarisin on tert-butylhydroperoxide-induced oxidative damage in rat primary hepato-cytes. Arch Toxicol. 1999;73:263-268.
    • (1999) Arch Toxicol , vol.73 , pp. 263-268
    • Chu, C.Y.1    Tseng, T.H.2    Hwang, J.M.3


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