-
2
-
-
0033609165
-
Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver
-
Kohli V, Selzner M, Madden JF, Bentley RC, Clavien PA. Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver. Transplantation 1999; 67: 1099-1105.
-
(1999)
Transplantation
, vol.67
, pp. 1099-1105
-
-
Kohli, V.1
Selzner, M.2
Madden, J.F.3
Bentley, R.C.4
Clavien, P.A.5
-
3
-
-
0033005752
-
A caspase inhibitor fully protects rats against lethal normothermic liver ischemia by inhibition of liver apoptosis
-
Cursio R, Gugenheim J, Ricci JE, Crenesse D, Rostagno P, Maulon L et al. A caspase inhibitor fully protects rats against lethal normothermic liver ischemia by inhibition of liver apoptosis. FASEB J 1999; 13: 253-261.
-
(1999)
FASEB J
, vol.13
, pp. 253-261
-
-
Cursio, R.1
Gugenheim, J.2
Ricci, J.E.3
Crenesse, D.4
Rostagno, P.5
Maulon, L.6
-
4
-
-
0141594593
-
Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury
-
Jaeschke H, Lemasters JJ. Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury. Gastroenterology 2003; 125: 1246-1257.
-
(2003)
Gastroenterology
, vol.125
, pp. 1246-1257
-
-
Jaeschke, H.1
Lemasters, J.J.2
-
5
-
-
0035140552
-
Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: Apoptosis or necrosis?
-
Gujral J, Bucci T, Farhood A, Jaeschke H. Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: apoptosis or necrosis? Hepatology 2001; 33: 397-405.
-
(2001)
Hepatology
, vol.33
, pp. 397-405
-
-
Gujral, J.1
Bucci, T.2
Farhood, A.3
Jaeschke, H.4
-
6
-
-
0034991526
-
Mechanism of hepatocyte death after ischemia: Apoptosis versus necrosis
-
Clavien PA, Rudiger HA, Selzner M. Mechanism of hepatocyte death after ischemia: apoptosis versus necrosis. Hepatology 2001; 33: 1555-1557.
-
(2001)
Hepatology
, vol.33
, pp. 1555-1557
-
-
Clavien, P.A.1
Rudiger, H.A.2
Selzner, M.3
-
7
-
-
0036142543
-
Tumor necrosis factor α, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver
-
Rudiger HA, Clavien PA. Tumor necrosis factor α, but not Fas, mediates hepatocellular apoptosis in the murine ischemic liver. Gastroenterology 2002; 122: 202-210.
-
(2002)
Gastroenterology
, vol.122
, pp. 202-210
-
-
Rudiger, H.A.1
Clavien, P.A.2
-
8
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry NY, Lazebnik Y. Caspases: enemies within. Science 1998; 281: 1312-1316.
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.Y.1
Lazebnik, Y.2
-
9
-
-
0032575752
-
Mitochondria and apoptosis
-
Green DR, Reed JC. Mitochondria and apoptosis. Science 1998; 281: 1309-1312.
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
10
-
-
0032752063
-
Cellular survival: A play in three Akts
-
Datta SR, Brunet A, Greenberg ME. Cellular survival: a play in three Akts. Genes Dev 1999; 13: 2905-2927.
-
(1999)
Genes Dev
, vol.13
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
11
-
-
0034651983
-
Akt promotes survival of cardio-myocytes in vitro and protects against ischemia-reperfusion injury in mouse heart
-
Fujio Y, Nguyen T, Wencker D, Kitsis RN, Walsh K. Akt promotes survival of cardio-myocytes in vitro and protects against ischemia-reperfusion injury in mouse heart. Circulation 2000; 101: 660-667.
-
(2000)
Circulation
, vol.101
, pp. 660-667
-
-
Fujio, Y.1
Nguyen, T.2
Wencker, D.3
Kitsis, R.N.4
Walsh, K.5
-
12
-
-
0032743421
-
Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation
-
Daemen M, Van 'tVeer C, Denecker G, Heemskerk VH, Wolfs TG, Clauss M et al. Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation. J Clin Invest 1999; 104: 541-549.
-
(1999)
J Clin Invest
, vol.104
, pp. 541-549
-
-
Daemen, M.1
Van 'Tveer, C.2
Denecker, G.3
Heemskerk, V.H.4
Wolfs, T.G.5
Clauss, M.6
-
13
-
-
0037227666
-
PI3K signaling is required for prostaglandin-induced mucosal recovery in ischemia-injured porcine ileum
-
Little D, Dean RA, Young KM, McKane SA, Martin LD, Jones SL et al. PI3K signaling is required for prostaglandin-induced mucosal recovery in ischemia-injured porcine ileum. Am J Physiol Gastrointest Liver Physiol 2003; 284: G46-G56.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
-
-
Little, D.1
Dean, R.A.2
Young, K.M.3
McKane, S.A.4
Martin, L.D.5
Jones, S.L.6
-
14
-
-
0035658389
-
Akt protects mouse hepatocytes from TNF-α- and Fas-mediated apoptosis through NK-κB activation
-
Hatano E, Brenner DA. Akt protects mouse hepatocytes from TNF-α- and Fas-mediated apoptosis through NK-κB activation. Am J Physiol Gastrointest Liver Physiol 2001; 281: G1357-G1368.
-
(2001)
Am J Physiol Gastrointest Liver Physiol
, vol.281
-
-
Hatano, E.1
Brenner, D.A.2
-
15
-
-
0141590207
-
A-Lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway
-
Muller C, Dûnschede F, Koch E, Vollmar AM, Kiemer AK. A-Lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway. Am J Physiol Gastrointest Liver Physiol 2003; 285: G769-G778.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.285
-
-
Muller, C.1
Dûnschede, F.2
Koch, E.3
Vollmar, A.M.4
Kiemer, A.K.5
-
16
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995; 270: 1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
17
-
-
0031005579
-
Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases
-
Bradham CA, Stachlewitz RF, Gao W, Qian T, Jayadev S, Jenkins G et al. Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases. Hepatology 1997; 25: 1128-1135.
-
(1997)
Hepatology
, vol.25
, pp. 1128-1135
-
-
Bradham, C.A.1
Stachlewitz, R.F.2
Gao, W.3
Qian, T.4
Jayadev, S.5
Jenkins, G.6
-
18
-
-
0027946514
-
The stress-activated protein kinases are major c-Jun amino-terminal kinases activated by ischemia and reperfusion
-
Pombo CM, Bonventre JV, Avruch J, Woodgett JR, Kyriakis JM, Force T. The stress-activated protein kinases are major c-Jun amino-terminal kinases activated by ischemia and reperfusion. J Biol Chem 1994; 269: 26546-26551.
-
(1994)
J Biol Chem
, vol.269
, pp. 26546-26551
-
-
Pombo, C.M.1
Bonventre, J.V.2
Avruch, J.3
Woodgett, J.R.4
Kyriakis, J.M.5
Force, T.6
-
19
-
-
0032771415
-
Inhibition of mitogen-activated kinase signaling sensitizes HeLa cells to Fas receptor-mediated apoptosis
-
Holmstrom TH, Tran SE, Johnson VL, Ahn NG, Chow SC, Eriksson JE. Inhibition of mitogen-activated kinase signaling sensitizes HeLa cells to Fas receptor-mediated apoptosis. Mol Cell Biol 1999; 19: 5991-6002.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5991-6002
-
-
Holmstrom, T.H.1
Tran, S.E.2
Johnson, V.L.3
Ahn, N.G.4
Chow, S.C.5
Eriksson, J.E.6
-
20
-
-
0034658384
-
JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: Differential requirements for caspase activation
-
MacFarlane M, Cohen GM, Dickens M. JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: differential requirements for caspase activation. Biochem J 2000; 348: 93-101.
-
(2000)
Biochem J
, vol.348
, pp. 93-101
-
-
MacFarlane, M.1
Cohen, G.M.2
Dickens, M.3
-
21
-
-
0032795940
-
The mitogen-activated protein kinase kinase/extracellular signal-regulated kinase cascade activation is a key signalling pathway involved in the regulation of G(1) phase progression in proliferating hepatocytes
-
Talarmin H, Rescan C, Cariou S, Glaise D, Zanninelli G, Bilodeau M et al. The mitogen-activated protein kinase kinase/extracellular signal-regulated kinase cascade activation is a key signalling pathway involved in the regulation of G(1) phase progression in proliferating hepatocytes. Mol Cell Biol 1999; 19: 6003-6011.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6003-6011
-
-
Talarmin, H.1
Rescan, C.2
Cariou, S.3
Glaise, D.4
Zanninelli, G.5
Bilodeau, M.6
-
22
-
-
0033755073
-
Protein kinase activation by warm and cold hypoxia-reoxygenation in primary-cultured rat hepatocytes - JNK(1)/SAPK(1) involvement in apoptosis
-
Crenesse D, Gugenheim J, Hornoy J, Tornieri K, Laurens M, Cambien B et al. Protein kinase activation by warm and cold hypoxia-reoxygenation in primary-cultured rat hepatocytes - JNK(1)/SAPK(1) involvement in apoptosis. Hepatology 2000; 32: 1029-1036.
-
(2000)
Hepatology
, vol.32
, pp. 1029-1036
-
-
Crenesse, D.1
Gugenheim, J.2
Hornoy, J.3
Tornieri, K.4
Laurens, M.5
Cambien, B.6
-
23
-
-
0041326612
-
Protection of rat hepatocytes from apoptosis by inhibition of c-Jun N-terminal kinase
-
Marderstein EL, Bucher B, Guo Z, Feng X, Reid K, Geller DA. Protection of rat hepatocytes from apoptosis by inhibition of c-Jun N-terminal kinase. Surgery 2003; 134: 280-284.
-
(2003)
Surgery
, vol.134
, pp. 280-284
-
-
Marderstein, E.L.1
Bucher, B.2
Guo, Z.3
Feng, X.4
Reid, K.5
Geller, D.A.6
-
24
-
-
0033912843
-
Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation
-
Filippa N, Sable CL, Hemmings B, Van Obberghen E. Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation. Mol Cell Biol 2000; 20: 5712-5721.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5712-5721
-
-
Filippa, N.1
Sable, C.L.2
Hemmings, B.3
Van Obberghen, E.4
-
25
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone MH, Roy N, Stennicke HR, Salvesen GS, Franke TF, Stanbridge E et al. Regulation of cell death protease caspase-9 by phosphorylation. Science 1998; 282: 1318-1321.
-
(1998)
Science
, vol.282
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
Salvesen, G.S.4
Franke, T.F.5
Stanbridge, E.6
-
26
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunei A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999; 96: 857-868.
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunei, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
-
27
-
-
0032128301
-
Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress
-
Zundel W, Giaccia A. Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress. Genes Dev 1998; 12: 1941-1946.
-
(1998)
Genes Dev
, vol.12
, pp. 1941-1946
-
-
Zundel, W.1
Giaccia, A.2
-
28
-
-
0036166348
-
Transgenic mice overexpressing Bcl-2 are resistant to hepatic ischemia and reperfusion
-
Selzner M, Rudiger HA, Selzner N, Thomas DW, Sindram D, Clavien PA. Transgenic mice overexpressing Bcl-2 are resistant to hepatic ischemia and reperfusion. J Hepatol 2002; 36: 218-225.
-
(2002)
J Hepatol
, vol.36
, pp. 218-225
-
-
Selzner, M.1
Rudiger, H.A.2
Selzner, N.3
Thomas, D.W.4
Sindram, D.5
Clavien, P.A.6
-
29
-
-
0033975366
-
Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis
-
Rokudai S, Fujita N, Hashimoto Y, Tsuruo T. Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis. J Cell Physiol 2000; 182: 290-296.
-
(2000)
J Cell Physiol
, vol.182
, pp. 290-296
-
-
Rokudai, S.1
Fujita, N.2
Hashimoto, Y.3
Tsuruo, T.4
-
30
-
-
0030566872
-
The MAP kinase cascades are activated during post-ischemic liver reperfusion
-
Bendinelli P, Piccoletti R, Maroni P, Bernelli Zazzera A. The MAP kinase cascades are activated during post-ischemic liver reperfusion. FEBS Lett 1996; 398: 193-197.
-
(1996)
FEBS Lett
, vol.398
, pp. 193-197
-
-
Bendinelli, P.1
Piccoletti, R.2
Maroni, P.3
Bernelli Zazzera, A.4
-
31
-
-
0031590798
-
Activation of c-Jun N-terminal kinase during ischemia and reperfusion in mouse liver
-
Onishi I, Tani T, Hashimoto T, Shimizu K, Yagi M, Yamamoto K et al. Activation of c-Jun N-terminal kinase during ischemia and reperfusion in mouse liver. FEBS Lett 1997; 420: 201-204.
-
(1997)
FEBS Lett
, vol.420
, pp. 201-204
-
-
Onishi, I.1
Tani, T.2
Hashimoto, T.3
Shimizu, K.4
Yagi, M.5
Yamamoto, K.6
-
32
-
-
0036125604
-
P38 mitogen-activated protein kinase inhibition attenuates ischemia-reperfusion injury of the rat liver
-
Kobayashi M, Takeyoshi I, Yoshinari D, Matsumoto K, Morishita Y. P38 mitogen-activated protein kinase inhibition attenuates ischemia-reperfusion injury of the rat liver. Surgery 2002; 131: 344-349.
-
(2002)
Surgery
, vol.131
, pp. 344-349
-
-
Kobayashi, M.1
Takeyoshi, I.2
Yoshinari, D.3
Matsumoto, K.4
Morishita, Y.5
-
33
-
-
0033581927
-
Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway
-
Fang X, Yu S, Eder A, Mao M, Bast RC Jr, Boyd D et al. Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway. Oncogens 1999; 18: 6635-6640.
-
(1999)
Oncogens
, vol.18
, pp. 6635-6640
-
-
Fang, X.1
Yu, S.2
Eder, A.3
Mao, M.4
Bast Jr., R.C.5
Boyd, D.6
-
34
-
-
0030755466
-
Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney
-
Yin T, Sandhu G, Wolfgang CD, Barrier A, Webb RL, Rigel DF et al. Tissue-specific pattern of stress kinase activation in ischemic/reperfused heart and kidney. J Biol Chem 1997; 272: 19943-19950.
-
(1997)
J Biol Chem
, vol.272
, pp. 19943-19950
-
-
Yin, T.1
Sandhu, G.2
Wolfgang, C.D.3
Barrier, A.4
Webb, R.L.5
Rigel, D.F.6
-
35
-
-
0033950358
-
The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor alpha-mediated rat hepatocyte survival and apoptosis
-
Roberts RA, James NH, Cosulich SC. The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor alpha-mediated rat hepatocyte survival and apoptosis. Hepatology 2000; 31: 420-427.
-
(2000)
Hepatology
, vol.31
, pp. 420-427
-
-
Roberts, R.A.1
James, N.H.2
Cosulich, S.C.3
-
36
-
-
0034710303
-
P38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons
-
Ghatan J, Larner S, Kinoshita Y, Hetman M, Patel L, Xia Z et al. P38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons. J Cell Biol 2000; 150: 335-347.
-
(2000)
J Cell Biol
, vol.150
, pp. 335-347
-
-
Ghatan, J.1
Larner, S.2
Kinoshita, Y.3
Hetman, M.4
Patel, L.5
Xia, Z.6
-
37
-
-
0037428458
-
Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3
-
Zhang X, Shan P, Otterbein LE, Alam J, Flavell RA, Davis RJ et al. Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3. J Biol Chem 2003; 278: 1248-1258.
-
(2003)
J Biol Chem
, vol.278
, pp. 1248-1258
-
-
Zhang, X.1
Shan, P.2
Otterbein, L.E.3
Alam, J.4
Flavell, R.A.5
Davis, R.J.6
-
38
-
-
0035133227
-
Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
-
Kim AH, Khursigara G, Sun X, Franke TF, Chao MV. Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. Mol Cell Biol 2001; 21: 893-901.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 893-901
-
-
Kim, A.H.1
Khursigara, G.2
Sun, X.3
Franke, T.F.4
Chao, M.V.5
-
39
-
-
17144392548
-
The Akt/PKB family of protein kinases: A review of small molecule inhibitors and progress towards target validation
-
Barnett SF, Bilodeau MT, Lindsley CW. The Akt/PKB family of protein kinases: a review of small molecule inhibitors and progress towards target validation. Curr Top Med Chem 2005; 5: 109-125.
-
(2005)
Curr Top Med Chem
, vol.5
, pp. 109-125
-
-
Barnett, S.F.1
Bilodeau, M.T.2
Lindsley, C.W.3
-
40
-
-
0034845958
-
PKB/Akt: A key mediator of cell proliferation, survival and insulin responses?
-
Lawlor MA, Alessi DR. PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? J Cell Sci 2001; 114: 2903-2910.
-
(2001)
J Cell Sci
, vol.114
, pp. 2903-2910
-
-
Lawlor, M.A.1
Alessi, D.R.2
|