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Volumn 19, Issue 3, 2010, Pages 227-235

Genetics of early-onset obsessive-compulsive disorder

Author keywords

Brain derived neurotrophic factor; Early onset; Glutamate transporter gene; Obsessive compulsive disorder; Serotonin

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CATECHOL METHYLTRANSFERASE; DOPAMINE 4 RECEPTOR; EXCITATORY AMINO ACID TRANSPORTER 3; NEUROTRANSMITTER; SEROTONIN 2A RECEPTOR; SEROTONIN RECEPTOR; SEROTONIN TRANSPORTER; TRYPTOPHAN HYDROXYLASE 2;

EID: 77950860590     PISSN: 10188827     EISSN: 1435165X     Source Type: Journal    
DOI: 10.1007/s00787-010-0087-7     Document Type: Review
Times cited : (70)

References (59)
  • 1
    • 0036249511 scopus 로고    scopus 로고
    • An exploratory study on obsessive-compulsive disorder with and without a familial component: Are there any phenomenological differences?
    • DOI 10.1159/000056210
    • U Albert G Maina L Ravizza F Bogetto 2002 An exploratory study on obsessive-compulsive disorder with and without a familial component: are there any phenomenological differences? Psychopathology 35 8 16 10.1159/000056210 12006743 (Pubitemid 34507688)
    • (2002) Psychopathology , vol.35 , Issue.1 , pp. 8-16
    • Albert, U.1    Maina, G.2    Ravizza, L.3    Bogetto, F.4
  • 3
    • 27144475229 scopus 로고    scopus 로고
    • Updated overview of the putative role of the serotoninergic system in obsessive-compulsive disorder
    • 1:CAS:528:DC%2BD28XhtlarsrrK
    • B Aouizerate D Guehl E Cuny A Rougier P Burbaud J Tignol B Bioulac 2005 Updated overview of the putative role of the serotoninergic system in obsessive-compulsive disorder Neuropsychiatric Dis Treat 1 231 243 1:CAS:528:DC%2BD28XhtlarsrrK
    • (2005) Neuropsychiatric Dis Treat , vol.1 , pp. 231-243
    • Aouizerate, B.1    Guehl, D.2    Cuny, E.3    Rougier, A.4    Burbaud, P.5    Tignol, J.6    Bioulac, B.7
  • 4
    • 29444459269 scopus 로고    scopus 로고
    • Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse
    • DOI 10.1038/nn1609
    • K Aoyama SW Suh AM Hamby J Liu WY Chan Y Chen RA Swanson 2006 Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse Nat Neurosci 9 119 126 10.1038/nn1609 1:CAS:528: DC%2BD2MXhtlCms7vO 16311588 (Pubitemid 43011917)
    • (2006) Nature Neuroscience , vol.9 , Issue.1 , pp. 119-126
    • Aoyama, K.1    Sang, W.S.2    Hamby, A.M.3    Liu, J.4    Wai, Y.C.5    Chen, Y.6    Swanson, R.A.7
  • 5
    • 4344567868 scopus 로고    scopus 로고
    • Association of a glutamate (NMDA) subunit receptor gene (GRIN2B) with obsessive-compulsive disorder: A preliminary study
    • PD Arnold DR Rosenberg E Mundo S Tharmalingam JL Kennedy MA Richter 2004 Association of a glutamate (NMDA) subunit receptor gene (GRIN2B) with obsessive-compulsive disorder: a preliminary study Psychopharmacology (Berl) 174 530 538 10.1007/s00213-004-1847-1 1:CAS:528:DC%2BD2cXmt1Kksrs%3D (Pubitemid 39119342)
    • (2004) Psychopharmacology , vol.174 , Issue.4 , pp. 530-538
    • Arnold, P.D.1    Rosenberg, D.R.2    Mundo, E.3    Tharmalingam, S.4    Kennedy, J.L.5    Richter, M.A.6
  • 6
    • 33646687079 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha gene is not associated with obsessive-compulsive disorder
    • DOI 10.1097/01.ypg.0000185026.12687.92, PII 0004144420060200000009
    • PD Arnold T Sicard E Burroughs MA Richter JL Kennedy 2006 Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder Arch Gen Psychiatry 63 769 776 10.1001/archpsyc.63.7.769 1:CAS:528:DC%2BD28XnsFGls7w%3D 16818866 (Pubitemid 44481220)
    • (2006) Psychiatric Genetics , vol.16 , Issue.1 , pp. 43-45
    • Zai, G.1    Arnold, P.D.2    Burroughs, E.3    Richter, M.A.4    Kennedy, J.L.5
  • 7
    • 0026635532 scopus 로고
    • Psychiatric disorders in the families of patients with obsessive-compulsive disorder
    • 10.1016/0165-1781(92)90075-E 1:STN:280:DyaK38zjsFCluw%3D%3D 1631248
    • L Bellodi G Sciuto G Diaferia P Ronchi E Smeraldi 1992 Psychiatric disorders in the families of patients with obsessive-compulsive disorder Psychiatry Res 42 111 120 10.1016/0165-1781(92)90075-E 1:STN:280: DyaK38zjsFCluw%3D%3D 1631248
    • (1992) Psychiatry Res , vol.42 , pp. 111-120
    • Bellodi, L.1    Sciuto, G.2    Diaferia, G.3    Ronchi, P.4    Smeraldi, E.5
  • 8
    • 0026628834 scopus 로고
    • A family study of obsessive-compulsive disorder
    • 1:STN:280:DyaK383msVyktg%3D%3D 1586271
    • DW Black R Noyes Jr RB Goldstein N Blum 1992 A family study of obsessive-compulsive disorder Arch Gen Psychiatry 49 362 368 1:STN:280:DyaK383msVyktg%3D%3D 1586271
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 362-368
    • Black, D.W.1    Noyes Jr, R.2    Goldstein, R.B.3    Blum, N.4
  • 9
    • 57349191646 scopus 로고    scopus 로고
    • Meta-analysis of the symptom structure of obsessive-compulsive disorder
    • 10.1176/appi.ajp.2008.08020320 18923068
    • MH Bloch A Landeros-Weisenberger MC Rosario C Pittenger JF Leckman 2008 Meta-analysis of the symptom structure of obsessive-compulsive disorder Am J Psychiatry 165 1532 1542 10.1176/appi.ajp.2008.08020320 18923068
    • (2008) Am J Psychiatry , vol.165 , pp. 1532-1542
    • Bloch, M.H.1    Landeros-Weisenberger, A.2    Rosario, M.C.3    Pittenger, C.4    Leckman, J.F.5
  • 10
    • 33845984942 scopus 로고    scopus 로고
    • Obsessive-compulsive disorder, tics and anxiety in 6-year-old twins
    • DOI 10.1017/S0033291706008816, PII S0033291706008816
    • D Bolton F Rijsdijk TG O'Connor S Perrin TC Eley 2007 Obsessive-compulsive disorder, tics and anxiety in 6-year-old twins Psychol Med 37 39 48 10.1017/S0033291706008816 16999878 (Pubitemid 46043841)
    • (2007) Psychological Medicine , vol.37 , Issue.1 , pp. 39-48
    • Bolton, D.1    Rijsdijk, F.2    O'Connor, T.G.3    Perrin, S.4    Eley, T.C.5
  • 12
    • 27444445901 scopus 로고    scopus 로고
    • Glutamatergic dysfunction in OCD
    • DOI 10.1038/sj.npp.1300733, PII 1300733
    • K Chakrabarty S Bhattacharyya R Christopher S Khanna 2005 Glutamatergic dysfunction in OCD Neuropsychopharmacology 30 1735 1740 10.1038/sj.npp.1300733 1:CAS:528:DC%2BD2MXotFegurc%3D 15841109 (Pubitemid 43086030)
    • (2005) Neuropsychopharmacology , vol.30 , Issue.9 , pp. 1735-1740
    • Chakrabarty, K.1    Bhattacharyya, S.2    Christopher, R.3    Khanna, S.4
  • 16
    • 0033013030 scopus 로고    scopus 로고
    • Association between seasonal affective disorder and the 5-HT(2A) promoter polymorphism, -1438G/A
    • MA Enoch D Goldman R Barnett L Sher CM Mazzanti NE Rosenthal 1999 Association between seasonal affective disorder and the 5-HT2A promoter polymorphism, -1438G/A Mol Psychiatry 4 89 92 10.1038/sj.mp.4000439 1:CAS:528:DC%2BD3cXlvVWlsLY%3D 10089016 (Pubitemid 29050208)
    • (1999) Molecular Psychiatry , vol.4 , Issue.1 , pp. 89-92
    • Enoch, M.-A.1    Goldman, D.2    Barnett, R.3    Sher, L.4    Mazzanti, C.M.5    Rosenthal, N.E.6
  • 17
    • 0035865578 scopus 로고    scopus 로고
    • 2A promoter polymorphism with obsessive-compulsive disorder
    • DOI 10.1016/S0006-3223(00)01040-4, PII S0006322300010404
    • MA Enoch BD Greenberg DL Murphy D Goldman 2001 Sexually dimorphic relationship of a 5-HT2A promoter polymorphism with obsessive-compulsive disorder Biol Psychiatry 49 385 388 10.1016/S0006-3223(00)01040-4 1:CAS:528:DC%2BD3MXhs1Cjt7Y%3D 11239910 (Pubitemid 32182369)
    • (2001) Biological Psychiatry , vol.49 , Issue.4 , pp. 385-388
    • Enoch, M.-A.1    Greenberg, B.D.2    Murphy, D.L.3    Goldman, D.4
  • 19
    • 34548073024 scopus 로고    scopus 로고
    • Genetics of obsessive-compulsive disorder: A research update
    • DOI 10.1586/14737175.7.8.967
    • M Grados HC Wilcox 2007 Genetics of obsessive-compulsive disorder: a research update Expert Rev Neurother 7 967 980 10.1586/14737175.7.8.967 1:CAS:528:DC%2BD2sXos1Cms7w%3D 17678492 (Pubitemid 47287485)
    • (2007) Expert Review of Neurotherapeutics , vol.7 , Issue.8 , pp. 967-980
    • Grados, M.1    Wilcox, H.C.2
  • 20
    • 0042165043 scopus 로고    scopus 로고
    • Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder
    • DOI 10.1086/377003
    • D Hall A Dhilla A Charalambous JA Gogos M Karayiorgou 2003 Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder Am J Hum Genet 73 370 376 10.1086/377003 1:CAS:528:DC%2BD3sXmt1Snur8%3D 12836135 (Pubitemid 36920998)
    • (2003) American Journal of Human Genetics , vol.73 , Issue.2 , pp. 370-376
    • Hall, D.1    Dhilla, A.2    Charalambous, A.3    Gogos, J.A.4    Karayiorgou, M.5
  • 27
    • 20344385026 scopus 로고    scopus 로고
    • Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the national comorbidity survey replication
    • DOI 10.1001/archpsyc.62.6.593
    • RC Kessler P Berglund O Demler R Jin KR Merikangas EE Walters 2005 Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication Arch Gen Psychiatry 62 593 602 10.1001/archpsyc.62.6.593 15939837 (Pubitemid 40973434)
    • (2005) Archives of General Psychiatry , vol.62 , Issue.6 , pp. 593-602
    • Kessler, R.C.1    Berglund, P.2    Demler, O.3    Jin, R.4    Merikangas, K.R.5    Walters, E.E.6
  • 28
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • 10.1038/ng1195-241 1:CAS:528:DyaK2MXptlSjs74%3D 7581446
    • E Lander L Kruglyak 1995 Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results Nat Genet 11 241 247 10.1038/ng1195-241 1:CAS:528:DyaK2MXptlSjs74%3D 7581446
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.1    Kruglyak, L.2
  • 31
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
    • DOI 10.1126/science.274.5292.1527
    • KP Lesch D Bengel A Heils SZ Sabol BD Greenberg S Petri J Benjamin CR Muller DH Hamer DL Murphy 1996 Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region Science 274 1527 1531 10.1126/science.274.5292.1527 1:CAS:528:DyaK28Xnt1ansL8%3D 8929413 (Pubitemid 26403928)
    • (1996) Science , vol.274 , Issue.5292 , pp. 1527-1531
    • Lesch, K.-P.1    Bengel, D.2    Heils, A.3    Sabol, S.Z.4    Greenberg, B.D.5    Petri, S.6    Benjamin, J.7    Muller, C.R.8    Hamer, D.H.9    Murphy, D.L.10
  • 37
    • 38649099407 scopus 로고    scopus 로고
    • Targeting the murine serotonin transporter: Insights into human neurobiology
    • DOI 10.1038/nrn2284, PII NRN2284
    • DL Murphy KP Lesch 2008 Targeting the murine serotonin transporter: insights into human neurobiology Nat Rev Neurosci 9 85 96 10.1038/nrn2284 1:CAS:528:DC%2BD1cXovFGgtA%3D%3D 18209729 (Pubitemid 351164876)
    • (2008) Nature Reviews Neuroscience , vol.9 , Issue.2 , pp. 85-96
    • Murphy, D.L.1    Lesch, K.-P.2
  • 39
    • 0027358636 scopus 로고
    • Family study of obsessive-compulsive disorder in a Mexican population
    • H Nicolini K Weissbecker JM Mejia M Sanchez de Carmona 1993 Family study of obsessive-compulsive disorder in a Mexican population Arch Med Res 24 193 198 1:STN:280:DyaK2c7gtVKltg%3D%3D 8274848 (Pubitemid 23284566)
    • (1993) Archives of Medical Research , vol.24 , Issue.2 , pp. 193-198
    • Nicolini, H.1    Weissbecker, K.2    Mejia, J.M.3    De Carmona, M.S.4
  • 40
    • 0033943052 scopus 로고    scopus 로고
    • DADAR, a Drosophila double-stranded RNA-specific adenosine deaminase is highly developmentally regulated and is itself a target for RNA editing
    • DOI 10.1017/S1355838200000248
    • MJ Palladino LP Keegan MA O'Connell RA Reenan 2000 dADAR, a drosophila double-stranded RNA-specific adenosine deaminase is highly developmentally regulated and is itself a target for RNA editing RNA 6 1004 1018 10.1017/S1355838200000248 1:CAS:528:DC%2BD3cXlt1agtLc%3D 10917596 (Pubitemid 30471137)
    • (2000) RNA , vol.6 , Issue.7 , pp. 1004-1018
    • Palladino, M.J.1    Keegan, L.P.2    O'Connell, M.A.3    Reenan, R.A.4
  • 43
    • 30644462283 scopus 로고    scopus 로고
    • Glutamate-modulating drugs as novel pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder
    • DOI 10.1016/j.nurx.2005.12.006
    • C Pittenger JH Krystal V Coric 2006 Glutamate-modulating drugs as novel pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder NeuroRx 3 69 81 10.1016/j.nurx.2005.12.006 1:CAS:528:DC%2BD28Xksl2ntrY%3D 16490414 (Pubitemid 43276634)
    • (2006) NeuroRx , vol.3 , Issue.1 , pp. 69-81
    • Pittenger, C.1    Krystal, J.H.2    Coric, V.3
  • 48
    • 3042559713 scopus 로고    scopus 로고
    • Long-term outcome of pediatric obsessive-compulsive disorder: A meta-analysis and qualitative review of the literature
    • DOI 10.1111/j.1600-0447.2004.00302.x
    • SE Stewart DA Geller M Jenike D Pauls D Shaw B Mullin SV Faraone 2004 Long-term outcome of pediatric obsessive-compulsive disorder: a meta-analysis and qualitative review of the literature Acta Psychiatr Scand 110 4 13 10.1111/j.1600-0447.2004.00302.x 1:STN:280:DC%2BD2c3otVKhuw%3D%3D 15180774 (Pubitemid 38822642)
    • (2004) Acta Psychiatrica Scandinavica , vol.110 , Issue.1 , pp. 4-13
    • Stewart, S.E.1    Geller, D.A.2    Jenike, M.3    Pauls, D.4    Shaw, D.5    Mullin, B.6    Faraone, S.V.7
  • 51
    • 0035112137 scopus 로고    scopus 로고
    • Genomic organization of the SLC1A1/EAAC1 gene and mutation screening in early-onset obsessive-compulsive disorder
    • DOI 10.1038/sj.mp.4000806
    • J Veenstra-VanderWeele SJ Kim D Gonen GL Hanna BL Leventhal EH Cook Jr 2001 Genomic organization of the SLC1A1/EAAC1 gene and mutation screening in early-onset obsessive-compulsive disorder Mol Psychiatry 6 160 167 10.1038/sj.mp.4000806 1:CAS:528:DC%2BD3MXhsFGluro%3D 11317217 (Pubitemid 32187865)
    • (2001) Molecular Psychiatry , vol.6 , Issue.2 , pp. 160-167
    • Veenstra-Vanderweele, J.1    Kim, S.-J.2    Gonen, D.3    Hanna, G.L.4    Leventhal, B.L.5    Cook Jr., E.H.6
  • 52
    • 46649109721 scopus 로고    scopus 로고
    • Transmission disequilibrium studies in early onset of obsessive-compulsive disorder for polymorphisms in genes of the dopaminergic system
    • 10.1007/s00702-008-0051-6 1:CAS:528:DC%2BD1cXotV2mt7g%3D 18446263
    • S Walitza A Scherag TJ Renner A Hinney H Remschmidt B Herpertz-Dahlmann E Schulz H Schafer KW Lange C Wewetzer M Gerlach 2008 Transmission disequilibrium studies in early onset of obsessive-compulsive disorder for polymorphisms in genes of the dopaminergic system J Neural Transm 115 1071 1078 10.1007/s00702-008-0051-6 1:CAS:528:DC%2BD1cXotV2mt7g%3D 18446263
    • (2008) J Neural Transm , vol.115 , pp. 1071-1078
    • Walitza, S.1    Scherag, A.2    Renner, T.J.3    Hinney, A.4    Remschmidt, H.5    Herpertz-Dahlmann, B.6    Schulz, E.7    Schafer, H.8    Lange, K.W.9    Wewetzer, C.10    Gerlach, M.11
  • 55
    • 34548085906 scopus 로고    scopus 로고
    • A large case-control study of common functional SLC6A4 and BDNF variants in obsessive-compulsive disorder
    • DOI 10.1038/sj.npp.1301394, PII 1301394
    • JR Wendland MR Kruse KR Cromer DL Murphy 2007 A large case-control study of common functional SLC6A4 and BDNF variants in obsessive-compulsive disorder Neuropsychopharmacology 32 2543 2551 10.1038/sj.npp.1301394 1:CAS:528: DC%2BD2sXhtlWjsbjP 17375136 (Pubitemid 350126846)
    • (2007) Neuropsychopharmacology , vol.32 , Issue.12 , pp. 2543-2551
    • Wendland, J.R.1    Kruse, M.R.2    Cromer, K.C.3    Murphy, D.L.4
  • 56
    • 64849109213 scopus 로고    scopus 로고
    • A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder
    • 10.1001/archgenpsychiatry.2009.6 1:CAS:528:DC%2BD1MXltVWnt7g%3D 19349310
    • JR Wendland PR Moya KR Timpano AP Anavitarte MR Kruse MG Wheaton RF Ren-Patterson DL Murphy 2009 A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder Arch Gen Psychiatry 66 408 416 10.1001/archgenpsychiatry.2009.6 1:CAS:528:DC%2BD1MXltVWnt7g%3D 19349310
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 408-416
    • Wendland, J.R.1    Moya, P.R.2    Timpano, K.R.3    Anavitarte, A.P.4    Kruse, M.R.5    Wheaton, M.G.6    Ren-Patterson, R.F.7    Murphy, D.L.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.