Modeling co-expression across species for complex traits: Insights to the difference of human and mouse embryonic stem cells

PLoS Computational Biology

Volumn 6, Issue 3, 2010, Pages

  Cai, Jun ^a,f   Xie, Dan ^a   Fan, Zhewen ^a,b   Chipperfield, Hiram ^e   Marden, John ^b   Wong, Wing H ^c,d   Zhong, Sheng ^a,b  

^a University of Illinois at Urbana Champaign   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c STANFORD LAW SCHOOL   (United States)

^d STANFORD UNIVERSITY   (United States)

^e INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

^f Chinese Academy of Sciences and China National Center for Bioinformation   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SIGNALING; COMPLEX NETWORKS; MAMMALS; MAXIMUM LIKELIHOOD ESTIMATION; PROTEINS; STEM CELLS; TRANSCRIPTION;

CLUSTERINGS; CO-EXPRESSION; COMPLEX TRAITS; CROSS-SPECIES; EMBRYONIC STEM CELLS; MICE EMBRYONIC STEM CELLS; ORTHOLOGOUS GENES; PHENOTYPIC EVOLUTION; PLURIPOTENT; SPECIES SPECIFICS;

SIGNAL TRANSDUCTION;

GENE PRODUCT; KRUPPEL LIKE FACTOR 2; KRUPPEL LIKE FACTOR 4; KRUPPEL LIKE FACTOR 5; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN LIN28; PROTEIN NODAL; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; PROTEOME;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; GENE CLUSTER; GENE CONTROL; GENE EXPRESSION; GENE MAPPING; GENE TARGETING; GENETIC CONSERVATION; GENETIC MODEL; GENETIC TRAIT; GENETIC TRANSCRIPTION; HUMAN VERSUS ANIMAL COMPARISON; MOUSE; NONHUMAN; PHENOTYPE; PLURIPOTENT STEM CELL; PROTEIN DNA BINDING; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE; SPECIES IDENTIFICATION; ANIMAL; BIOLOGICAL MODEL; COMPUTER SIMULATION; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; PHYSIOLOGY;

MURINAE;

ANIMALS; COMPUTER SIMULATION; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION; HUMANS; MICE; MODELS, BIOLOGICAL; PROTEOME; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY;

EID: 77950847851     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000707     Document Type: Article

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