Cleft lip and palate results from hedgehog signaling antagonism in the mouse: Phenotypic characterization and clinical implications

Birth Defects Research Part A - Clinical and Molecular Teratology

Volumn 88, Issue 4, 2010, Pages 232-240

  Lipinski, Robert J ^a,b   Song, Chihwa ^a   Sulik, Kathleen K ^b   Everson, Joshua L ^a   Gipp, Jerry J ^a   Yan, Dong ^b   Bushman, Wade ^a   Rowland, Ian J ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Cleft lip; Cleft palate; Cyclopamine; Hedgehog signaling; Holoprosencephaly

Indexed keywords

CYCLOPAMINE; SONIC HEDGEHOG PROTEIN;

ADENOHYPOPHYSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APLASIA; ARTICLE; BRAIN MALFORMATION; CLEFT LIP PALATE; CRANIOFACIAL MALFORMATION; EMBRYO; FEMALE; FETUS; HOLOPROSENCEPHALY; HYPOPLASIA; MORPHOGENESIS; MORPHOLOGICAL TRAIT; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OLFACTORY BULB; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ABNORMALITIES, DRUG-INDUCED; ABNORMALITIES, MULTIPLE; ADMINISTRATION, ORAL; ANIMALS; CELLS, CULTURED; CLEFT LIP; CLEFT PALATE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETAL RESORPTION; FETUS; HEDGEHOG PROTEINS; HOLOPROSENCEPHALY; MATERNAL EXPOSURE; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, SCANNING; NIH 3T3 CELLS; OLFACTORY BULB; PHENOTYPE; PITUITARY GLAND, ANTERIOR; VERATRUM ALKALOIDS;

ANIMALIA; ERINACEIDAE; MUS;

EID: 77950831465     PISSN: 15420752     EISSN: 15420760     Source Type: Journal    
DOI: 10.1002/bdra.20656     Document Type: Article

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