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Volumn 61, Issue 4, 2002, Pages 248-256

Gene/environment causes of cleft lip and/or palate

Author keywords

Cleft lip; Cleft palate

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ANTICONVULSIVE AGENT; DIOXIN; ESTROGEN; FOLIC ACID; GENE PRODUCT; PHENYTOIN; PYRIDOXINE; RETINOIC ACID; THALIDOMIDE; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA3; VALPROIC ACID;

EID: 0036556368     PISSN: 00099163     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0004.2002.610402.x     Document Type: Review
Times cited : (577)

References (122)
  • 1
    • 0032911987 scopus 로고    scopus 로고
    • The organization and delivery of craniofacial health services: The state of the art
    • Strauss RP. The organization and delivery of craniofacial health services: the state of the art. Cleft Palate Craniofac J 1999: 36 (3): 189-195.
    • (1999) Cleft Palate Craniofac. J. , vol.36 , Issue.3 , pp. 189-195
    • Strauss, R.P.1
  • 2
    • 0023235059 scopus 로고
    • Incidence of cleft lip, cleft palate, and cleft lip and palate among races: A review
    • Vanderas AP. Incidence of cleft lip, cleft palate, and cleft lip and palate among races: a review. Cleft Palate J 1987: 24: 216-225.
    • (1987) Cleft Palate J. , vol.24 , pp. 216-225
    • Vanderas, A.P.1
  • 3
    • 8044220924 scopus 로고    scopus 로고
    • Clinical and epidemiologic studies of cleft lip and palate in the Philippines
    • Murray JC, Daack-Hirsch S, Buetow KH et al. Clinical and epidemiologic studies of cleft lip and palate in the Philippines. Cleft Palate J 1997: 34: 7-10.
    • (1997) Cleft Palate J. , vol.34 , pp. 7-10
    • Murray, J.C.1    Daack-Hirsch, S.2    Buetow, K.H.3
  • 4
    • 0035668985 scopus 로고    scopus 로고
    • The genetics and epigenetics of orofacial clefts
    • Spritz RA. The genetics and epigenetics of orofacial clefts. Curr Opin Pediatr 2001: 13 (6): 556-560.
    • (2001) Curr. Opin. Pediatr. , vol.13 , Issue.6 , pp. 556-560
    • Spritz, R.A.1
  • 6
    • 0023013493 scopus 로고
    • Cleft lip with or without cleft palate: Reanalysis of a three generation family study in England
    • Marazita ML, Goldstein AM, Smalley SL et al. Cleft lip with or without cleft palate: reanalysis of a three generation family study in England. Genet Epidemiol 1986: 3: 335-342.
    • (1986) Genet. Epidemiol. , vol.3 , pp. 335-342
    • Marazita, M.L.1    Goldstein, A.M.2    Smalley, S.L.3
  • 7
    • 84932732093 scopus 로고
    • Thoughts on the etiology of clefts of the palate and lip
    • Fraser FC. Thoughts on the etiology of clefts of the palate and lip. Acta Genet 1955: 5: 358-369.
    • (1955) Acta Genet. , vol.5 , pp. 358-369
    • Fraser, F.C.1
  • 8
    • 0024267719 scopus 로고
    • Etiology of facial clefts. Prospective evaluation of 428 patients
    • Jones MC. Etiology of facial clefts. Prospective evaluation of 428 patients. Cleft Palate J 1988: 25: 16-20.
    • (1988) Cleft Palate J. , vol.25 , pp. 16-20
    • Jones, M.C.1
  • 9
    • 0036143519 scopus 로고    scopus 로고
    • Guidelines for the design and analysis of studies on nonsyndromic cleft lip and cleft palate in humans: Summary report from a workshop of the international consortium for oral clefts genetics
    • Mitchell LE, Beaty TH, Lidral AC et al. Guidelines for the design and analysis of studies on nonsyndromic cleft lip and cleft palate in humans: summary report from a workshop of the international consortium for oral clefts genetics. Cleft Palate Craniofac J 2002: 39 (1): 93-100.
    • (2002) Cleft Palate Craniofac. J. , vol.39 , Issue.1 , pp. 93-100
    • Mitchell, L.E.1    Beaty, T.H.2    Lidral, A.C.3
  • 10
    • 0032231877 scopus 로고    scopus 로고
    • Comprehensive human genetic maps: Individual and sex-specific variation in recombination
    • Broman KW, Murray JC, Sheffield VC et al. Comprehensive human genetic maps: individual and sex-specific variation in recombination. Am J Hum Genet 1998: 63: 861-869.
    • (1998) Am. J. Hum. Genet. , vol.63 , pp. 861-869
    • Broman, K.W.1    Murray, J.C.2    Sheffield, V.C.3
  • 11
    • 0030066784 scopus 로고    scopus 로고
    • Analysis of the recurrence patterns for nonsyndromic cleft lip with or without cleft palate in the families of 3,073 Danish probands
    • Mitchell LE, Christensen K. Analysis of the recurrence patterns for nonsyndromic cleft lip with or without cleft palate in the families of 3,073 Danish probands. Am J Med Genet 1996: 61 (4): 371-376.
    • (1996) Am. J. Med. Genet. , vol.61 , Issue.4 , pp. 371-376
    • Mitchell, L.E.1    Christensen, K.2
  • 13
    • 0032881718 scopus 로고    scopus 로고
    • The many faces and factors of orofacial clefts
    • Schutte BC, Murray JC. The many faces and factors of orofacial clefts. Hum Mol Genet 1999: 8: 1853-1859.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 1853-1859
    • Schutte, B.C.1    Murray, J.C.2
  • 14
    • 0023176710 scopus 로고
    • Suggestion of linkage of a major locus for nonsyndromic orofacial cleft with F13A and tentative assignment to chromosome 6
    • Eiberg H, Bixler D, Nielsen LS et al. Suggestion of linkage of a major locus for nonsyndromic orofacial cleft with F13A and tentative assignment to chromosome 6. Clin Genet 1987: 32: 129-132.
    • (1987) Clin. Genet. , vol.32 , pp. 129-132
    • Eiberg, H.1    Bixler, D.2    Nielsen, L.S.3
  • 15
    • 0028797751 scopus 로고
    • Nonsyndromic cleft lip and palate: Evidence of linkage to a microsatellite marker on 6p23
    • Carinci F, Pezzetti F, Scapoli L et al. Nonsyndromic cleft lip and palate: evidence of linkage to a microsatellite marker on 6p23. Am J Hum Genet 1995: 56: 337-339.
    • (1995) Am. J. Hum. Genet. , vol.56 , pp. 337-339
    • Carinci, F.1    Pezzetti, F.2    Scapoli, L.3
  • 16
    • 0031571130 scopus 로고    scopus 로고
    • Evidence of linkage to 6p23 and genetic heterogeneity in nonsyndromic cleft lip with or without cleft palate
    • Scapoli L, Pezzetti F, Carinci F et al. Evidence of linkage to 6p23 and genetic heterogeneity in nonsyndromic cleft lip with or without cleft palate. Genomics 1997: 43: 216-220.
    • (1997) Genomics , vol.43 , pp. 216-220
    • Scapoli, L.1    Pezzetti, F.2    Carinci, F.3
  • 17
    • 0034033146 scopus 로고    scopus 로고
    • Identification of susceptibility loci for nonsyndromic cleft lip with or without cleft palate in a two stage genome scan of affected sibpairs
    • Prescott NJ, Lees MM, Winter RM et al. Identification of susceptibility loci for nonsyndromic cleft lip with or without cleft palate in a two stage genome scan of affected sibpairs. Hum Genet 2000: 106 (3): 345-350.
    • (2000) Hum. Genet. , vol.106 , Issue.3 , pp. 345-350
    • Prescott, N.J.1    Lees, M.M.2    Winter, R.M.3
  • 18
    • 0035254496 scopus 로고    scopus 로고
    • C677T variant from at the MTHFR gene and CL/P: A risk factor for mothers?
    • Martinelli M, Scapoli L, Pezzetti F et al. C677T variant from at the MTHFR gene and CL/P: a risk factor for mothers? Am J Med Genet 2001: 98 (4): 357-360.
    • (2001) Am. J. Med. Genet. , vol.98 , Issue.4 , pp. 357-360
    • Martinelli, M.1    Scapoli, L.2    Pezzetti, F.3
  • 19
    • 0035212763 scopus 로고    scopus 로고
    • Linkage analysis of three candidate regions of chromosome 1 in nonsyndromic familial orofacial cleft
    • Martinelli M, Scapoli L, Pezzetti F et al. Linkage analysis of three candidate regions of chromosome 1 in nonsyndromic familial orofacial cleft. Ann Hum Genet 2001: 65 (Pt 5): 465-471.
    • (2001) Ann. Hum. Genet. , vol.65 , Issue.PART 5 , pp. 465-471
    • Martinelli, M.1    Scapoli, L.2    Pezzetti, F.3
  • 20
    • 0034686437 scopus 로고    scopus 로고
    • No evidence supporting MTHFR as a risk factor in the development of familial NSCLP
    • Blanton SH, Kolle BS, Hecht JT et al. No evidence supporting MTHFR as a risk factor in the development of familial NSCLP. Am J Med Genet 2000: 92 (5): 370-371.
    • (2000) Am. J. Med. Genet. , vol.92 , Issue.5 , pp. 370-371
    • Blanton, S.H.1    Kolle, B.S.2    Hecht, J.T.3
  • 21
    • 0034193698 scopus 로고    scopus 로고
    • Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and risk of nonsyndromic cleft lip
    • Wyszynski DF, Diehl SR. Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and risk of nonsyndromic cleft lip. Am J Med Genet 2000: 92 (1): 79-80.
    • (2000) Am. J. Med. Genet. , vol.92 , Issue.1 , pp. 79-80
    • Wyszynski, D.F.1    Diehl, S.R.2
  • 22
    • 0032751289 scopus 로고    scopus 로고
    • Role of the C677T polymorphism at the MTHFR gene on risk to nonsyndromic cleft lip with/without cleft palate: Results from a case-control study in Brazil
    • Gaspar DA, Pavanello RC, Zatz M et al. Role of the C677T polymorphism at the MTHFR gene on risk to nonsyndromic cleft lip with/without cleft palate: results from a case-control study in Brazil. Am J Med Genet 1999: 87 (2): 197-199.
    • (1999) Am. J. Med. Genet. , vol.87 , Issue.2 , pp. 197-199
    • Gaspar, D.A.1    Pavanello, R.C.2    Zatz, M.3
  • 23
    • 0032802054 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase thermolabile variant and oral clefts
    • Mills JL, Kirke PN, Molloy AM et al. Methylenetetrahydrofolate reductase thermolabile variant and oral clefts. Am J Med Genet 1999: 86 (1): 71-74.
    • (1999) Am. J. Med. Genet. , vol.86 , Issue.1 , pp. 71-74
    • Mills, J.L.1    Kirke, P.N.2    Molloy, A.M.3
  • 24
    • 0033516526 scopus 로고    scopus 로고
    • Maternal vitamin use, infant C677T mutation in MTHFR, and isolated cleft palate risk
    • Shaw GM, Todoroff K, Finnell RH et al. Maternal vitamin use, infant C677T mutation in MTHFR, and isolated cleft palate risk. Am J Med Genet 1999: 85 (1): 84-85.
    • (1999) Am. J. Med. Genet. , vol.85 , Issue.1 , pp. 84-85
    • Shaw, G.M.1    Todoroff, K.2    Finnell, R.H.3
  • 25
    • 0031785528 scopus 로고    scopus 로고
    • Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and cleft lip
    • Shaw GM, Rozen R, Finnell RH et al. Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and cleft lip. Am J Med Genet 1998: 80: 196-198.
    • (1998) Am. J. Med. Genet. , vol.80 , pp. 196-198
    • Shaw, G.M.1    Rozen, R.2    Finnell, R.H.3
  • 26
    • 8044231337 scopus 로고    scopus 로고
    • Studies of the candidate genes TGFB2, MSX1, TGFA, and TGFB3 in the etiology of cleft lip and palate in the Philippines
    • Lidral AC, Murray JC, Buetow KH et al. Studies of the candidate genes TGFB2, MSX1, TGFA, and TGFB3 in the etiology of cleft lip and palate in the Philippines. Cleft Palate Craniofac J 1997: 34: 1-6.
    • (1997) Cleft Palate Craniofac. J. , vol.34 , pp. 1-6
    • Lidral, A.C.1    Murray, J.C.2    Buetow, K.H.3
  • 27
    • 0033854334 scopus 로고    scopus 로고
    • Analysis of the candidate genes responsible for non-syndromic cleft lip and palate in Japanese people
    • Tanabe A, Taketani S, Endo-Ichikawa Y et al. Analysis of the candidate genes responsible for non-syndromic cleft lip and palate in Japanese people. Clin Sci (London) 2000: 99 (2): 105-111.
    • (2000) Clin. Sci. (London) , vol.99 , Issue.2 , pp. 105-111
    • Tanabe, A.1    Taketani, S.2    Endo-Ichikawa, Y.3
  • 28
    • 0025762595 scopus 로고
    • Further evidence for an association between genetic variation in transforming growth factor alpha and cleft lip and palate
    • Chenevix-Trench G, Jones K, Green A et al. Further evidence for an association between genetic variation in transforming growth factor alpha and cleft lip and palate. Am J Hum Genet 1991: 48: 1012-1013.
    • (1991) Am. J. Hum. Genet. , vol.48 , pp. 1012-1013
    • Chenevix-Trench, G.1    Jones, K.2    Green, A.3
  • 29
    • 0026620226 scopus 로고
    • Cleft lip with or with or without cleft palate: Associations with transforming growth factor alpha and retinoic acid receptor loci
    • Chenevix-Trench G, Jones K, Green AC et al. Cleft lip with or with or without cleft palate: associations with transforming growth factor alpha and retinoic acid receptor loci. Am J Hum Genet 1992: 51: 1377-1385.
    • (1992) Am. J. Hum. Genet. , vol.51 , pp. 1377-1385
    • Chenevix-Trench, G.1    Jones, K.2    Green, A.C.3
  • 30
    • 0028004410 scopus 로고
    • Evidence, from family studies, for linkage disequilibrium between TGFA and a gene for nonsyndromic cleft lip with or without cleft palate
    • Feng H, Sassani R, Bartlett SP et al. Evidence, from family studies, for linkage disequilibrium between TGFA and a gene for nonsyndromic cleft lip with or without cleft palate. Am J Hum Genet 1994: 55: 932-936.
    • (1994) Am. J. Hum. Genet. , vol.55 , pp. 932-936
    • Feng, H.1    Sassani, R.2    Bartlett, S.P.3
  • 31
    • 0026763353 scopus 로고
    • Confirmation of an association between RFLPs at the transforming growth factor-alpha locus and non-syndromic cleft lip and palate
    • Holder SE, Vintiner GM, Farren B et al. Confirmation of an association between RFLPs at the transforming growth factor-alpha locus and non-syndromic cleft lip and palate. J Med Genet 1992: 29: 390-392.
    • (1992) J. Med. Genet. , vol.29 , pp. 390-392
    • Holder, S.E.1    Vintiner, G.M.2    Farren, B.3
  • 32
    • 0030671069 scopus 로고    scopus 로고
    • Application of transmission disequilibrium tests to nonsyndromic oral clefts: Including candidate genes and environmental exposures in the models
    • Maestri NE, Beaty TH, Hetmanski J et al. Application of transmission disequilibrium tests to nonsyndromic oral clefts: including candidate genes and environmental exposures in the models. Am J Med Genet 1997: 73 (3): 337-344.
    • (1997) Am. J. Med. Genet. , vol.73 , Issue.3 , pp. 337-344
    • Maestri, N.E.1    Beaty, T.H.2    Hetmanski, J.3
  • 33
    • 0032526776 scopus 로고    scopus 로고
    • A locus in 2p13-p14 (OFC2), in addition to that mapped in 6p23, is involved in nonsyndromic familial orofacial cleft malformation
    • Pezzetti F, Scapoli L, Martinelli M et al. A locus in 2p13-p14 (OFC2), in addition to that mapped in 6p23, is involved in nonsyndromic familial orofacial cleft malformation. Genomics 1998: 50: 299-305.
    • (1998) Genomics , vol.50 , pp. 299-305
    • Pezzetti, F.1    Scapoli, L.2    Martinelli, M.3
  • 34
    • 0026684102 scopus 로고
    • No evidence of linkage between the transforming growth factor-alpha gene in families with apparently autosomal dominant inheritance of cleft lip and palate
    • Vintiner GM, Holder SE, Winter RM et al. No evidence of linkage between the transforming growth factor-alpha gene in families with apparently autosomal dominant inheritance of cleft lip and palate. J Med Genet 1992: 29: 393-397.
    • (1992) J. Med. Genet. , vol.29 , pp. 393-397
    • Vintiner, G.M.1    Holder, S.E.2    Winter, R.M.3
  • 35
    • 0033081772 scopus 로고    scopus 로고
    • Oral clefts, transforming-growth-factor-alpha gene variants, and maternal smoking: A population based case-control study in Denmark 1991-1994
    • Christensen K, Olsen J, Norgaard-Pedersen B et al. Oral clefts, transforming-growth-factor-alpha gene variants, and maternal smoking: a population based case-control study in Denmark 1991-1994. Am J Epidemiol 1999: 149: 248-255.
    • (1999) Am. J. Epidemiol. , vol.149 , pp. 248-255
    • Christensen, K.1    Olsen, J.2    Norgaard-Pedersen, B.3
  • 36
    • 0028145109 scopus 로고
    • Transforming growth factor alpha: A modifying locus for nonsyndromic cleft lip with or without cleft palate?
    • Field LL, Ray AK, Marazita ML. Transforming growth factor alpha: a modifying locus for nonsyndromic cleft lip with or without cleft palate? Eur J Hum Genet 1994: 2 (3): 159-165.
    • (1994) Eur. J. Hum. Genet. , vol.2 , Issue.3 , pp. 159-165
    • Field, L.L.1    Ray, A.K.2    Marazita, M.L.3
  • 37
    • 0029043080 scopus 로고
    • Association between alleles of the transforming growth factor alpha locus and cleft lip and palate in the Chilean population
    • Jara L, Blanco R, Chiffelle I et al. Association between alleles of the transforming growth factor alpha locus and cleft lip and palate in the Chilean population. Am J Med Genet 1995: 57 (4): 548-551.
    • (1995) Am. J. Med. Genet. , vol.57 , Issue.4 , pp. 548-551
    • Jara, L.1    Blanco, R.2    Chiffelle, I.3
  • 38
    • 0027492864 scopus 로고
    • Association of transforming growth-factor alpha gene polymorphisms with nonsyndromic cleft palate only (CPO)
    • Shiang R, Lidral AC, Ardinger HH et al. Association of transforming growth-factor alpha gene polymorphisms with nonsyndromic cleft palate only (CPO). Am J Hum Genet 1993: 53 (4): 836-843.
    • (1993) Am. J. Hum. Genet. , vol.53 , Issue.4 , pp. 836-843
    • Shiang, R.1    Lidral, A.C.2    Ardinger, H.H.3
  • 39
    • 0032759066 scopus 로고    scopus 로고
    • Transforming growth factor-alpha (TGFA): Genomic structure, boundary sequences, and mutation analysis in nonsyndromic cleft lip/palate and cleft palate only
    • Machida J, Yoshiura K, Funkhauser CD et al. Transforming growth factor-alpha (TGFA): genomic structure, boundary sequences, and mutation analysis in nonsyndromic cleft lip/palate and cleft palate only. Genomics 1999: 61 (3): 237-242.
    • (1999) Genomics , vol.61 , Issue.3 , pp. 237-242
    • Machida, J.1    Yoshiura, K.2    Funkhauser, C.D.3
  • 40
    • 0032231873 scopus 로고    scopus 로고
    • Association of MSX1 and TGFB3 with nonsyndromic clefting in humans
    • Lidral AC, Romitti PA, Basart AM et al. Association of MSX1 and TGFB3 with nonsyndromic clefting in humans. Am J Hum Genet 1998: 63: 557-568.
    • (1998) Am. J. Hum. Genet. , vol.63 , pp. 557-568
    • Lidral, A.C.1    Romitti, P.A.2    Basart, A.M.3
  • 41
    • 0036136187 scopus 로고    scopus 로고
    • Testing candidate genes for non-syndromic oral clefts using a case-parent trio design
    • Beaty TH, Hetmanski JB, Zeiger JS et al. Testing candidate genes for non-syndromic oral clefts using a case-parent trio design. Genet Epidemiol 2002: 22 (1): 1-11.
    • (2002) Genet. Epidemiol. , vol.22 , Issue.1 , pp. 1-11
    • Beaty, T.H.1    Hetmanski, J.B.2    Zeiger, J.S.3
  • 42
    • 0034933328 scopus 로고    scopus 로고
    • A case-control study of nonsyndromic oral clefts in Maryland
    • Beaty TH, Wang H, Hetmanski JB et al. A case-control study of nonsyndromic oral clefts in Maryland. Ann Epidemiol 2001: 11 (6): 434-442.
    • (2001) Ann. Epidemiol. , vol.11 , Issue.6 , pp. 434-442
    • Beaty, T.H.1    Wang, H.2    Hetmanski, J.B.3
  • 43
    • 0028970498 scopus 로고
    • Evidence for an association between nonsyndromic cleft lip with or without cleft palate and a gene located on the long arm of chromosome 4
    • Mitchell LE, Healy SC, Chenevix-Trench G. Evidence for an association between nonsyndromic cleft lip with or without cleft palate and a gene located on the long arm of chromosome 4. Am J Hum Genet 1995: 57: 1130-1136.
    • (1995) Am. J. Hum. Genet. , vol.57 , pp. 1130-1136
    • Mitchell, L.E.1    Healy, S.C.2    Chenevix-Trench, G.3
  • 44
    • 0027358433 scopus 로고
    • Further evidence of a relationship between the retinoic acid receptor alpha locus and nonsyndromic cleft lip with or without cleft palate
    • Shaw G, Ray A, Marazita M. Further evidence of a relationship between the retinoic acid receptor alpha locus and nonsyndromic cleft lip with or without cleft palate. Am J Hum Genet 1993: 53: 1156-1157.
    • (1993) Am. J. Hum. Genet. , vol.53 , pp. 1156-1157
    • Shaw, G.1    Ray, A.2    Marazita, M.3
  • 45
    • 0029079365 scopus 로고
    • Nonsyndromic cleft lip with or without cleft palate: Evidence of linkage to BCL3 in 17 multigenerational families
    • Stein J, Mulliken JB, Stal S et al. Nonsyndromic cleft lip with or without cleft palate: evidence of linkage to BCL3 in 17 multigenerational families. Am J Hum Genet 1995: 57: 257-272.
    • (1995) Am. J. Hum. Genet. , vol.57 , pp. 257-272
    • Stein, J.1    Mulliken, J.B.2    Stal, S.3
  • 46
    • 0031060648 scopus 로고    scopus 로고
    • Evidence for an association between markers on chromosome 19q and non-syndromic cleft lip with or without cleft palate in two groups of multiplex families
    • Wyszynski DF, Maestri N, McIntosh I et al. Evidence for an association between markers on chromosome 19q and non-syndromic cleft lip with or without cleft palate in two groups of multiplex families. Hum Genet 1996: 99: 22-26.
    • (1996) Hum. Genet. , vol.99 , pp. 22-26
    • Wyszynski, D.F.1    Maestri, N.2    McIntosh, I.3
  • 47
    • 0030870848 scopus 로고    scopus 로고
    • Chromosome 1p36 deletions: The clinical phenotype and molecular characterization of a common newly delineated syndrome
    • Shapira SK, McCaskill C, Northrup H et al. Chromosome 1p36 deletions: the clinical phenotype and molecular characterization of a common newly delineated syndrome. Am J Hum Genet 1997: 61 (3): 642-650.
    • (1997) Am. J. Hum. Genet. , vol.61 , Issue.3 , pp. 642-650
    • Shapira, S.K.1    McCaskill, C.2    Northrup, H.3
  • 48
    • 0034660559 scopus 로고    scopus 로고
    • Searching for genetic determinants in the new millennium
    • 6788
    • Risch NJ. Searching for genetic determinants in the new millennium. Nature 2000: 405 (6788): 847-856.
    • (2000) Nature , vol.405 , pp. 847-856
    • Risch, N.J.1
  • 49
    • 0033820535 scopus 로고    scopus 로고
    • Genetic and teratogenic approaches to craniofacial development
    • Young DL, Schneider RA, Hu D et al. Genetic and teratogenic approaches to craniofacial development. Crit Rev Oral Biol Medical 2000: 11 (3): 304-317.
    • (2000) Crit. Rev. Oral Biol. Medical , vol.11 , Issue.3 , pp. 304-317
    • Young, D.L.1    Schneider, R.A.2    Hu, D.3
  • 50
    • 0024432231 scopus 로고
    • Association of genetic variation of the transforming growth factor-alpha gene with cleft lip and palate
    • Ardinger HH, Buetow KH, Bell GI et al. Association of genetic variation of the transforming growth factor-alpha gene with cleft lip and palate. Am J Hum Genet 1989: 45: 348-353.
    • (1989) Am. J. Hum. Genet. , vol.45 , pp. 348-353
    • Ardinger, H.H.1    Buetow, K.H.2    Bell, G.I.3
  • 51
    • 0030993005 scopus 로고    scopus 로고
    • Transforming growth factor alpha locus and nonsyndromic cleft lip with or without cleft palate: A re-appraisal
    • Mitchell LE. Transforming growth factor alpha locus and nonsyndromic cleft lip with or without cleft palate: a re-appraisal. Genet Epidemiol 1997: 14: 231-240.
    • (1997) Genet. Epidemiol. , vol.14 , pp. 231-240
    • Mitchell, L.E.1
  • 52
    • 0032930859 scopus 로고    scopus 로고
    • Epidermal growth factor receptor function is necessary for normal craniofacial development and palate closure
    • Miettinen PJ, Chin JR, Shum L et al. Epidermal growth factor receptor function is necessary for normal craniofacial development and palate closure. Nat Genet 1999: 22 (1): 69-73.
    • (1999) Nat. Genet. , vol.22 , Issue.1 , pp. 69-73
    • Miettinen, P.J.1    Chin, J.R.2    Shum, L.3
  • 53
    • 0034028899 scopus 로고    scopus 로고
    • MSX1 mutation is associated with orofacial clefting and tooth agenesis in humans
    • van den Boogaard MJH, Dorland M, Beemer FA et al. MSX1 mutation is associated with orofacial clefting and tooth agenesis in humans. Nat Genet 2000: 24: 342-343.
    • (2000) Nat. Genet. , vol.24 , pp. 342-343
    • van den Boogaard, M.J.H.1    Dorland, M.2    Beemer, F.A.3
  • 54
    • 0030017452 scopus 로고    scopus 로고
    • A human MSX1 homeodomain missense mutation causes selective tooth agenesis
    • Vastardis H, Karimbux N, Guthua SW et al. A human MSX1 homeodomain missense mutation causes selective tooth agenesis. Nat Genet 1996: 13 (4): 417-421.
    • (1996) Nat. Genet. , vol.13 , Issue.4 , pp. 417-421
    • Vastardis, H.1    Karimbux, N.2    Guthua, S.W.3
  • 55
    • 0032231333 scopus 로고    scopus 로고
    • A chromosomal deletion map of human malformations
    • Brewer C, Holloway S, Zawalnyski P et al. A chromosomal deletion map of human malformations. Am J Hum Genet 1998: 63: 1153-1159.
    • (1998) Am. J. Hum. Genet. , vol.63 , pp. 1153-1159
    • Brewer, C.1    Holloway, S.2    Zawalnyski, P.3
  • 56
    • 0033361899 scopus 로고    scopus 로고
    • A chromosomal duplication map of malformations: Regions of suspected haplo- and triplolethality - And tolerance of segmental aneuploidy - In humans
    • Brewer C, Holloway S, Zawalnyski P et al. A chromosomal duplication map of malformations: regions of suspected haplo- and triplolethality - and tolerance of segmental aneuploidy - in humans. Am J Hum Genet 1999: 64: 1702-1708.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 1702-1708
    • Brewer, C.1    Holloway, S.2    Zawalnyski, P.3
  • 57
    • 0034425423 scopus 로고    scopus 로고
    • Mutations of PVRL1, encoding a cell-cell adhesion molecule/herpesvirus receptor, in cleft lip/palate-ectodermal dysplasia
    • Suzuki K, Hu D, Bustos T et al. Mutations of PVRL1, encoding a cell-cell adhesion molecule/herpesvirus receptor, in cleft lip/palate-ectodermal dysplasia. Nat Genet 2000: 25 (4): 427-430.
    • (2000) Nat. Genet. , vol.25 , Issue.4 , pp. 427-430
    • Suzuki, K.1    Hu, D.2    Bustos, T.3
  • 58
    • 0034789530 scopus 로고    scopus 로고
    • Mutation of PVRL1 is associated with sporadic, non-syndromic cleft lip/palate in northern Venezuela
    • Sözen MA, Suzuki K, Tolarova MM et al. Mutation of PVRL1 is associated with sporadic, non-syndromic cleft lip/palate in northern Venezuela. Nat Genet 2001: 29 (2): 141-142.
    • (2001) Nat. Genet. , vol.29 , Issue.2 , pp. 141-142
    • Sözen, M.A.1    Suzuki, K.2    Tolarova, M.M.3
  • 59
    • 0034785347 scopus 로고    scopus 로고
    • Time for T
    • Murray JC. Time for T. Nat Genet 2001: 29 (2): 107-109.
    • (2001) Nat. Genet. , vol.29 , Issue.2 , pp. 107-109
    • Murray, J.C.1
  • 60
    • 0034785350 scopus 로고    scopus 로고
    • The T-box transcription factor gene TBX22 is mutated in X-linked cleft palate and ankyloglossia
    • Braybrook C, Doudney K, Marcano AC et al. The T-box transcription factor gene TBX22 is mutated in X-linked cleft palate and ankyloglossia. Nat Genet 2001: 29 (2): 179-183.
    • (2001) Nat. Genet. , vol.29 , Issue.2 , pp. 179-183
    • Braybrook, C.1    Doudney, K.2    Marcano, A.C.3
  • 61
    • 0034892604 scopus 로고    scopus 로고
    • p63 Gene mutations in eec syndrome, limb-mammary syndrome and isolated split hand-split foot malformation suggest a genotype-phenotype correlation
    • van Bokhoven H, Hamel BC, Bamshad M et al. p63 Gene mutations in eec syndrome, limb-mammary syndrome and isolated split hand-split foot malformation suggest a genotype-phenotype correlation. Am J Hum Genet 2001: 69 (3): 481-492.
    • (2001) Am. J. Hum. Genet. , vol.69 , Issue.3 , pp. 481-492
    • van Bokhoven, H.1    Hamel, B.C.2    Bamshad, M.3
  • 62
    • 0033954225 scopus 로고    scopus 로고
    • A preliminary gene map for the Van der Woude syndrome critical region derived from 900 kb of genomic sequence at 1q32-q41
    • Schutte BC, Bjork BC, Coppage KB et al. A preliminary gene map for the Van der Woude syndrome critical region derived from 900 kb of genomic sequence at 1q32-q41. Genome Res 2000: 10 (1): 81-94.
    • (2000) Genome Res. , vol.10 , Issue.1 , pp. 81-94
    • Schutte, B.C.1    Bjork, B.C.2    Coppage, K.B.3
  • 63
    • 0030609894 scopus 로고    scopus 로고
    • TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypes
    • Sanford LP, Ormsby I, Gittenberger-de Groot AC et al. TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypes. Development 1997: 124: 2659-2670.
    • (1997) Development , vol.124 , pp. 2659-2670
    • Sanford, L.P.1    Ormsby, I.2    Gittenberger-de Groot, A.C.3
  • 64
    • 0032506118 scopus 로고    scopus 로고
    • AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric mice
    • Nottoli T, Hagopian-Donaldson S, Zhang J et al. AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric mice. Proc Natl Acad Sci U S A 1998: 95: 13714-13719.
    • (1998) Proc. Natl. Acad. Sci. U S A , vol.95 , pp. 13714-13719
    • Nottoli, T.1    Hagopian-Donaldson, S.2    Zhang, J.3
  • 65
    • 0034426014 scopus 로고    scopus 로고
    • Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk
    • Halford MM, Armes J, Buchert M et al. Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk. Nat Genet 2000: 25 (4): 414-418.
    • (2000) Nat. Genet. , vol.25 , Issue.4 , pp. 414-418
    • Halford, M.M.1    Armes, J.2    Buchert, M.3
  • 66
    • 0036334452 scopus 로고    scopus 로고
    • Loss of the SKI proto-oncogene in individuals affected with 1p36 deletion syndrome is predicted by strain-dependent defects in Ski -/- mice
    • Colmenares C, Heilstedt HA, Shaffer LG et al. Loss of the SKI proto-oncogene in individuals affected with 1p36 deletion syndrome is predicted by strain-dependent defects in Ski -/- mice. Nat Genet 2001: 30 (1): 106-109.
    • (2001) Nat. Genet. , vol.30 , Issue.1 , pp. 106-109
    • Colmenares, C.1    Heilstedt, H.A.2    Shaffer, L.G.3
  • 67
    • 0032169255 scopus 로고    scopus 로고
    • Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities
    • Peters H, Neubuser A, Kratochwil K et al. Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities. Genes Dev 1998: 12: 2735-2747.
    • (1998) Genes Dev. , vol.12 , pp. 2735-2747
    • Peters, H.1    Neubuser, A.2    Kratochwil, K.3
  • 68
    • 0030955889 scopus 로고    scopus 로고
    • Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: Mutations of Dlx-1, Dlx-2 and Dlx- and - 2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches
    • Qiu M, Bulfone A, Ghattas I et al. Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2 and Dlx- and - 2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches. Dev Biol 1997: 185: 165-184.
    • (1997) Dev. Biol. , vol.185 , pp. 165-184
    • Qiu, M.1    Bulfone, A.2    Ghattas, I.3
  • 69
    • 0035016264 scopus 로고    scopus 로고
    • Unravelling the complex genetics of cleft lip in the mouse model
    • Juriloff DM, Harris MJ, Brown CJ. Unravelling the complex genetics of cleft lip in the mouse model. Mamm Genome 2001: 12 (6): 426-435.
    • (2001) Mamm. Genome , vol.12 , Issue.6 , pp. 426-435
    • Juriloff, D.M.1    Harris, M.J.2    Brown, C.J.3
  • 70
    • 0031000206 scopus 로고    scopus 로고
    • Genome scan for teratogen-induced clefting susceptibility loci in the mouse. Evidence of both allelic and locus heterogeneity distinguishing cleft lip and cleft palate
    • Diehl SR, Erickson RP. Genome scan for teratogen-induced clefting susceptibility loci in the mouse. Evidence of both allelic and locus heterogeneity distinguishing cleft lip and cleft palate. Proc Natl Acad Sci U S A 1997: 94: 5231-5236.
    • (1997) Proc. Natl. Acad. Sci. U S A , vol.94 , pp. 5231-5236
    • Diehl, S.R.1    Erickson, R.P.2
  • 71
    • 0028292605 scopus 로고
    • Msxl deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development
    • Satokata I, Maas R. Msxl deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development. Nat Genet 1994: 6: 348-356.
    • (1994) Nat. Genet. , vol.6 , pp. 348-356
    • Satokata, I.1    Maas, R.2
  • 72
    • 0031193368 scopus 로고    scopus 로고
    • Insertional mutation of the mouse Msxl homeobox gene by an nlacZ reporter gene
    • Houzelstein D, Cohen A, Buckingham ME et al. Insertional mutation of the mouse Msxl homeobox gene by an nlacZ reporter gene. Mech Dev 1997: 65: 123-133.
    • (1997) Mech. Dev. , vol.65 , pp. 123-133
    • Houzelstein, D.1    Cohen, A.2    Buckingham, M.E.3
  • 73
    • 0028806184 scopus 로고
    • Abnormal lung development and cleft palate in mice lacking TGF-b3 indicates defects of epithelial-mesenchymal interaction
    • Kaartinen V, Voncken JW, Shuler C et al. Abnormal lung development and cleft palate in mice lacking TGF-b3 indicates defects of epithelial-mesenchymal interaction. Nat Genet 1995: 11: 415-421.
    • (1995) Nat. Genet. , vol.11 , pp. 415-421
    • Kaartinen, V.1    Voncken, J.W.2    Shuler, C.3
  • 74
    • 0028972869 scopus 로고
    • Transforming growth factor-b3 is required for secondary palate fusion
    • Proetzel G, Pawlowski SA, Wiles MV et al. Transforming growth factor-b3 is required for secondary palate fusion. Nat Genet 1995: 11: 409-414.
    • (1995) Nat. Genet. , vol.11 , pp. 409-414
    • Proetzel, G.1    Pawlowski, S.A.2    Wiles, M.V.3
  • 75
    • 0030953268 scopus 로고    scopus 로고
    • Transforming growth factor-β-3 regulates transdifferentiation of medial edge epithelium during palatal fusion and associated degradation of the basement membrane
    • Kaartinen V, Cui X-M, Heisterkamp N et al. Transforming growth factor-β-3 regulates transdifferentiation of medial edge epithelium during palatal fusion and associated degradation of the basement membrane. Dev Dyn 1997: 209: 255-260.
    • (1997) Dev. Dyn. , vol.209 , pp. 255-260
    • Kaartinen, V.1    Cui, X.-M.2    Heisterkamp, N.3
  • 76
    • 0025287681 scopus 로고
    • Differential expression of TGF beta isoforms in murine palatogenesis
    • Fitzpatrick DR, Denhez F, Kondaiah P et al. Differential expression of TGF beta isoforms in murine palatogenesis. Development 1990: 109: 585-595.
    • (1990) Development , vol.109 , pp. 585-595
    • Fitzpatrick, D.R.1    Denhez, F.2    Kondaiah, P.3
  • 77
    • 0031594269 scopus 로고    scopus 로고
    • TGFB3 promotes transformation of chicken palate medial edge epithelium to mesenchyme in vitro
    • Sun D, Vanderburg CR, Odierna GS et al. TGFB3 promotes transformation of chicken palate medial edge epithelium to mesenchyme in vitro. Development 1998: 125: 95-105.
    • (1998) Development , vol.125 , pp. 95-105
    • Sun, D.1    Vanderburg, C.R.2    Odierna, G.S.3
  • 78
    • 0029932086 scopus 로고    scopus 로고
    • Transcription factor AP-2 essential for cranial closure and craniofacial development
    • Schorle H, Meier P, Buchert M et al. Transcription factor AP-2 essential for cranial closure and craniofacial development. Nature 1996: 381: 235-238.
    • (1996) Nature , vol.381 , pp. 235-238
    • Schorle, H.1    Meier, P.2    Buchert, M.3
  • 79
    • 0026849641 scopus 로고
    • Association of autosomal dominant cleft lip and palate and translocation 6p23;9q22.3
    • Donnai D, Heather LJ, Sinclair P et al. Association of autosomal dominant cleft lip and palate and translocation 6p23;9q22.3. Clin Dysmorphol 1992: 1: 89-97.
    • (1992) Clin. Dysmorphol. , vol.1 , pp. 89-97
    • Donnai, D.1    Heather, L.J.2    Sinclair, P.3
  • 80
    • 0031658337 scopus 로고    scopus 로고
    • Further evidence for the involvement of human chromosome 6p24 in the aetiology of orofacial clefting
    • Davies AF, Imaizumi K, Mirza G et al. Further evidence for the involvement of human chromosome 6p24 in the aetiology of orofacial clefting. J Med Genet 1998: 35: 857-861.
    • (1998) J. Med. Genet. , vol.35 , pp. 857-861
    • Davies, A.F.1    Imaizumi, K.2    Mirza, G.3
  • 81
    • 12644290240 scopus 로고    scopus 로고
    • Mice devoid of γ-aminobutryrate type A receptor β3 subunit have epilepsy, cleft palate, and hypersensitive behavior
    • Homanics GE, DeLorey TM, Firestone LL et al. Mice devoid of γ-aminobutryrate type A receptor β3 subunit have epilepsy, cleft palate, and hypersensitive behavior. Proc Natl Acad Sci U S A 1997: 94: 4143-4148.
    • (1997) Proc. Natl. Acad. Sci. U S A , vol.94 , pp. 4143-4148
    • Homanics, G.E.1    DeLorey, T.M.2    Firestone, L.L.3
  • 82
    • 0036461228 scopus 로고    scopus 로고
    • Linkage disequilibrium between GABRB3 gene and nonsyndromic familial cleft lip with or without cleft palate
    • Scapoli L, Martinelli M, Pezzetti F et al. Linkage disequilibrium between GABRB3 gene and nonsyndromic familial cleft lip with or without cleft palate. Hum Genet 2002: 110 (1): 15-20.
    • (2002) Hum. Genet. , vol.110 , Issue.1 , pp. 15-20
    • Scapoli, L.1    Martinelli, M.2    Pezzetti, F.3
  • 83
    • 0034817060 scopus 로고    scopus 로고
    • Increased incidence of a midline brain anomaly in patients with nonsyndromic clefts of the lip and/or palate
    • Nopoulos P, Berg S, VanDemark D et al. Increased incidence of a midline brain anomaly in patients with nonsyndromic clefts of the lip and/or palate. J Neuroimag 2001: 11 (4): 418-424.
    • (2001) J. Neuroimag. , vol.11 , Issue.4 , pp. 418-424
    • Nopoulos, P.1    Berg, S.2    VanDemark, D.3
  • 84
    • 0012524297 scopus 로고
    • Congenital malformations induced in rats by maternal nutritional deficiency
    • Warkany J, Nelson RC, Schraffenberger E. Congenital malformations induced in rats by maternal nutritional deficiency. Am J Dis Child 1943: 65: 882-894.
    • (1943) Am. J. Dis. Child , vol.65 , pp. 882-894
    • Warkany, J.1    Nelson, R.C.2    Schraffenberger, E.3
  • 85
    • 0029758424 scopus 로고    scopus 로고
    • Review of the role of potential teratogens in the origin of human nonsyndromic oral clefts
    • Wyszynski DF, Beaty TH. Review of the role of potential teratogens in the origin of human nonsyndromic oral clefts. Teratology 1996: 53: 309-317.
    • (1996) Teratology , vol.53 , pp. 309-317
    • Wyszynski, D.F.1    Beaty, T.H.2
  • 86
    • 0032906780 scopus 로고    scopus 로고
    • Parental agricultural work and selected congenital malformations
    • Garcia AM, Fletcher T, Benavides FG et al. Parental agricultural work and selected congenital malformations. Am J Epidemiol 1999: 149: 64-74.
    • (1999) Am. J. Epidemiol. , vol.149 , pp. 64-74
    • Garcia, A.M.1    Fletcher, T.2    Benavides, F.G.3
  • 88
    • 0012608671 scopus 로고
    • Update on the occurrence rate of cleft lip and palate
    • Lasa CI, Manalo PD. Update on the occurrence rate of cleft lip and palate. Phil J Surg Spec 1989: 44: 109-111.
    • (1989) Phil. J. Surg. Spec. , vol.44 , pp. 109-111
    • Lasa, C.I.1    Manalo, P.D.2
  • 90
    • 0023608443 scopus 로고
    • Genetic epidemiology of cleft lip with or without cleft palate in the population of Hawaii
    • Chung CS, Mi MP, Beechert AM. Genetic epidemiology of cleft lip with or without cleft palate in the population of Hawaii. Genet Epidemiol 1987: 4 (6): 415-423.
    • (1987) Genet. Epidemiol. , vol.4 , Issue.6 , pp. 415-423
    • Chung, C.S.1    Mi, M.P.2    Beechert, A.M.3
  • 91
    • 0031667418 scopus 로고    scopus 로고
    • Racial and ethnic variations in the prevalence of orofacial clefts in California, 1983-1992
    • Croen LA, Shaw GM, Wasserman CR et al. Racial and ethnic variations in the prevalence of orofacial clefts in California, 1983-1992. Am J Med Genet 1998: 79 (1): 42-47.
    • (1998) Am. J. Med. Genet. , vol.79 , Issue.1 , pp. 42-47
    • Croen, L.A.1    Shaw, G.M.2    Wasserman, C.R.3
  • 92
    • 0029053191 scopus 로고
    • Absence of an environmental effect on the recurrence of facial-cleft defects
    • Christensen K, Schmidt MM, Vaeth M et al. Absence of an environmental effect on the recurrence of facial-cleft defects. New Engl J Med 1995: 333: 161-164.
    • (1995) New Engl. J. Med. , vol.333 , pp. 161-164
    • Christensen, K.1    Schmidt, M.M.2    Vaeth, M.3
  • 93
    • 0034071589 scopus 로고    scopus 로고
    • Maternal risk factors in cleft lip and palate: Case control study
    • Natsume N, Kawai T, Ogi N et al. Maternal risk factors in cleft lip and palate: case control study. Br J Oral Maxillofac Surg 2000: 38 (1): 23-25.
    • (2000) Br. J. Oral Maxillofac. Surg. , vol.38 , Issue.1 , pp. 23-25
    • Natsume, N.1    Kawai, T.2    Ogi, N.3
  • 94
    • 0033215277 scopus 로고    scopus 로고
    • Maternal cigarett smoking during pregnancy and risk of oral clefts in newborns
    • Lieff S, Olshan AF, Werler M et al. Maternal cigarett smoking during pregnancy and risk of oral clefts in newborns. Am J Epidemiol 1999: 150 (7): 683-694.
    • (1999) Am. J. Epidemiol. , vol.150 , Issue.7 , pp. 683-694
    • Lieff, S.1    Olshan, A.F.2    Werler, M.3
  • 95
    • 0033969853 scopus 로고    scopus 로고
    • Maternal cigarette smoking during pregnancy and the risk of having a child with cleft lip/palate
    • Chung KC, Kowalski CP, Kim HM et al. Maternal cigarette smoking during pregnancy and the risk of having a child with cleft lip/palate. Plast Reconstr Surg 2000: 105 (2): 485-491.
    • (2000) Plast. Reconstr. Surg. , vol.105 , Issue.2 , pp. 485-491
    • Chung, K.C.1    Kowalski, C.P.2    Kim, H.M.3
  • 96
    • 0034009141 scopus 로고    scopus 로고
    • Tobacco and alcohol use during pregnancy and risk of oral clefts
    • Occupational Exposure and Congenital Malformation Working Group
    • Lorente C, Cordier S, Goujard J et al. Tobacco and alcohol use during pregnancy and risk of oral clefts. Occupational Exposure and Congenital Malformation Working Group. Am J Public Health 2000: 90 (3): 415-419.
    • (2000) Am. J. Public Health , vol.90 , Issue.3 , pp. 415-419
    • Lorente, C.1    Cordier, S.2    Goujard, J.3
  • 98
    • 0025016436 scopus 로고
    • Maternal cigarette smoking during pregnancy in relation to oral clefts
    • Werler M, Lammer EJ, Rosenberg L et al. Maternal cigarette smoking during pregnancy in relation to oral clefts. Am J Epidemiol 1990: 132: 926-932.
    • (1990) Am. J. Epidemiol. , vol.132 , pp. 926-932
    • Werler, M.1    Lammer, E.J.2    Rosenberg, L.3
  • 99
    • 0033506695 scopus 로고    scopus 로고
    • Maternal periconceptional alcohol consumption and risk for orofacial clefts
    • Shaw GM, Lammer EJ. Maternal periconceptional alcohol consumption and risk for orofacial clefts. J Pediatr 1999: 134 (3): 298-303.
    • (1999) J. Pediatr. , vol.134 , Issue.3 , pp. 298-303
    • Shaw, G.M.1    Lammer, E.J.2
  • 100
    • 0029854517 scopus 로고    scopus 로고
    • Maternal alcohol use and risk of orofacial cleft birth defects
    • Munger RG, Romitti PA, Daack-Hirsch S et al. Maternal alcohol use and risk of orofacial cleft birth defects. Teratology 1996: 54 (1): 27-33.
    • (1996) Teratology , vol.54 , Issue.1 , pp. 27-33
    • Munger, R.G.1    Romitti, P.A.2    Daack-Hirsch, S.3
  • 101
    • 0029151571 scopus 로고
    • Risks of orofacial clefts in children born to women using multivitamins containing folic acid periconceptionally
    • Shaw G, Lammer EJ, Wasserman CR et al. Risks of orofacial clefts in children born to women using multivitamins containing folic acid periconceptionally. Lancet 1995: 346: 393-396.
    • (1995) Lancet , vol.346 , pp. 393-396
    • Shaw, G.1    Lammer, E.J.2    Wasserman, C.R.3
  • 102
    • 0019985118 scopus 로고
    • Periconceptional supplementation with vitamins and folic acid to prevent recurrence of cleft lip
    • Tolarova M. Periconceptional supplementation with vitamins and folic acid to prevent recurrence of cleft lip. Lancet 1982: 2: 217.
    • (1982) Lancet , vol.2 , pp. 217
    • Tolarova, M.1
  • 103
    • 0030696738 scopus 로고    scopus 로고
    • Evolving methods in genetic epidemiology. III. Gene-environment interaction in epidemiologic research
    • Yang Q, Khoury MJ. Evolving methods in genetic epidemiology. III. Gene-environment interaction in epidemiologic research. Epidemiol Rev 1997: 19: 33-43.
    • (1997) Epidemiol. Rev. , vol.19 , pp. 33-43
    • Yang, Q.1    Khoury, M.J.2
  • 104
    • 0033643838 scopus 로고    scopus 로고
    • Environment and genetics in the etiology of cleft lip and cleft palate with reference to the role of folic acid
    • Bianchi F, Calzolari E, Ciulli L et al. Environment and genetics in the etiology of cleft lip and cleft palate with reference to the role of folic acid. Epidemiol Prev 2000: 24 (1): 21-27.
    • (2000) Epidemiol. Prev. , vol.24 , Issue.1 , pp. 21-27
    • Bianchi, F.1    Calzolari, E.2    Ciulli, L.3
  • 105
    • 9844229072 scopus 로고    scopus 로고
    • Testing for interaction between maternal smoking and TGFA genotype among oral cleft cases born in Maryland 1992-1996
    • Beaty TH, Maestri NE, Hetmanski JB et al. Testing for interaction between maternal smoking and TGFA genotype among oral cleft cases born in Maryland 1992-1996. Cleft Palate Craniofac J 1997: 34: 447-454.
    • (1997) Cleft Palate Craniofac. J. , vol.34 , pp. 447-454
    • Beaty, T.H.1    Maestri, N.E.2    Hetmanski, J.B.3
  • 106
    • 0032989710 scopus 로고    scopus 로고
    • Candidate genes for nonsyndromic cleft lip and palate and maternal cigarette smoking and alcohol consumption: Evaluation of genotype-environment interactions from a population-based case-control study of orofacial clefts
    • Romitti PA, Lidral AC, Munger RG et al. Candidate genes for nonsyndromic cleft lip and palate and maternal cigarette smoking and alcohol consumption: evaluation of genotype-environment interactions from a population-based case-control study of orofacial clefts. Teratology 1999: 59: 39-50.
    • (1999) Teratology , vol.59 , pp. 39-50
    • Romitti, P.A.1    Lidral, A.C.2    Munger, R.G.3
  • 107
    • 0030029864 scopus 로고    scopus 로고
    • Orofacial clefts, parental cigarette smoking, and transforming growth factor-alpha gene variants
    • Shaw GM, Wasserman CR, Lammer EJ et al. Orofacial clefts, parental cigarette smoking, and transforming growth factor-alpha gene variants. Am J Hum Genet 1996: 58: 551-561.
    • (1996) Am. J. Hum. Genet. , vol.58 , pp. 551-561
    • Shaw, G.M.1    Wasserman, C.R.2    Lammer, E.J.3
  • 108
    • 0031815048 scopus 로고    scopus 로고
    • Infant TGF-alpha genotype, orofacial clefts, and maternal periconceptional multivitamin use
    • Shaw G, Wasserman CR, Murray JC et al. Infant TGF-alpha genotype, orofacial clefts, and maternal periconceptional multivitamin use. Cleft Palate Craniofac J 1998: 35: 366-370.
    • (1998) Cleft Palate Craniofac. J. , vol.35 , pp. 366-370
    • Shaw, G.1    Wasserman, C.R.2    Murray, J.C.3
  • 109
    • 0035873124 scopus 로고    scopus 로고
    • Evaluation of two putative susceptibility loci for oral clefts in the Danish population
    • Mitchell LE, Murray JC, O'Brien S et al. Evaluation of two putative susceptibility loci for oral clefts in the Danish population. Am J Epidemiol 2001: 153 (10): 1007-1015.
    • (2001) Am. J. Epidemiol. , vol.153 , Issue.10 , pp. 1007-1015
    • Mitchell, L.E.1    Murray, J.C.2    O'Brien, S.3
  • 110
    • 0034891127 scopus 로고    scopus 로고
    • Smoking, genetic polymorphisms in biotransformation enzymes, and nonsyndromic oral clefting: A gene-environment interaction
    • van Rooj IA, Wegerif MJ, Roelofs HM et al. Smoking, genetic polymorphisms in biotransformation enzymes, and nonsyndromic oral clefting: a gene-environment interaction. Epidemiology 2001: 12 (5): 502-507.
    • (2001) Epidemiology , vol.12 , Issue.5 , pp. 502-507
    • van Rooj, I.A.1    Wegerif, M.J.2    Roelofs, H.M.3
  • 111
    • 0035934005 scopus 로고    scopus 로고
    • Analysis of the EPHX1 113 polymorphism and GSTM1 homozygous null polymorphism and oral clefting associated with maternal smoking
    • Hartsfield JK Jr, Hickman TA, Everett ET et al. Analysis of the EPHX1 113 polymorphism and GSTM1 homozygous null polymorphism and oral clefting associated with maternal smoking. Am J Med Genet 2001: 102 (1): 21-24.
    • (2001) Am. J. Med. Genet. , vol.102 , Issue.1 , pp. 21-24
    • Hartsfield J.K., Jr.1    Hickman, T.A.2    Everett, E.T.3
  • 113
    • 0029022223 scopus 로고
    • Reduced recurrence of orofacial clefts after periconceptional supplementation with high-dose folic acid and multivitamins
    • Tolarova M, Harris J. Reduced recurrence of orofacial clefts after periconceptional supplementation with high-dose folic acid and multivitamins. Teratology 1995: 51: 71-78.
    • (1995) Teratology , vol.51 , pp. 71-78
    • Tolarova, M.1    Harris, J.2
  • 114
    • 0029893565 scopus 로고    scopus 로고
    • Case-control study of periconceptional folic acid supplementation and oral clefts
    • Hayes C, Werler MM, Willett WC et al. Case-control study of periconceptional folic acid supplementation and oral clefts. Am J Epidemiol 1996: 143: 1229-1234.
    • (1996) Am. J. Epidemiol. , vol.143 , pp. 1229-1234
    • Hayes, C.1    Werler, M.M.2    Willett, W.C.3
  • 115
    • 0032893230 scopus 로고    scopus 로고
    • Analysis of select folate pathway genes, PAX3, and human T in a Midwestern neural tube defect population
    • Trembath D, Sherbondy AL, Vandyke DC et al. Analysis of select folate pathway genes, PAX3, and human T in a Midwestern neural tube defect population. Teratology 1999: 59 (5): 331-341.
    • (1999) Teratology , vol.59 , Issue.5 , pp. 331-341
    • Trembath, D.1    Sherbondy, A.L.2    Vandyke, D.C.3
  • 116
    • 0032540271 scopus 로고    scopus 로고
    • Endocrine disruptors signal the need for receptor models and mechanisms to inform policy
    • Limbird LE, Taylor P. Endocrine disruptors signal the need for receptor models and mechanisms to inform policy. Cell 1998: 93: 157-163.
    • (1998) Cell , vol.93 , pp. 157-163
    • Limbird, L.E.1    Taylor, P.2
  • 117
    • 0031773906 scopus 로고    scopus 로고
    • Role of TGF-β in RA-induced cleft palate in CD-1 mice
    • Degitz SJ, Morris D, Foley GL et al. Role of TGF-β in RA-induced cleft palate in CD-1 mice. Teratology 1998: 58: 197-204.
    • (1998) Teratology , vol.58 , pp. 197-204
    • Degitz, S.J.1    Morris, D.2    Foley, G.L.3
  • 118
    • 0031694284 scopus 로고    scopus 로고
    • Differential expression and biological activity of retinoic acid-induced TGFB isoforms in embryonic palate mesenchymal cells
    • Nugent P, Ma L, Greene RM. Differential expression and biological activity of retinoic acid-induced TGFB isoforms in embryonic palate mesenchymal cells. J Cell Physiol 1998: 177: 36-46.
    • (1998) J. Cell Physiol. , vol.177 , pp. 36-46
    • Nugent, P.1    Ma, L.2    Greene, R.M.3
  • 119
    • 0030093934 scopus 로고    scopus 로고
    • Comparative teratological studies on TCDD, Endrin and Lindane in C57BL/6J and DBA/2J mice
    • Hassoun EA, Stohs SJ. Comparative teratological studies on TCDD, Endrin and Lindane in C57BL/6J and DBA/2J mice. Comp Biochem Physiol 1996: 113C: 393-398.
    • (1996) Comp. Biochem. Physiol. , vol.113 C , pp. 393-398
    • Hassoun, E.A.1    Stohs, S.J.2
  • 120
    • 7144242310 scopus 로고    scopus 로고
    • Mesenchymal changes associated with retinoic acid induced cleft palate in CD-1 mice
    • Degitz SJ, Francis BM, Foley GL. Mesenchymal changes associated with retinoic acid induced cleft palate in CD-1 mice. J Craniofac Genet Dev Biol 1998: 18 (2): 88-99.
    • (1998) J. Craniofac. Genet. Dev. Biol. , vol.18 , Issue.2 , pp. 88-99
    • Degitz, S.J.1    Francis, B.M.2    Foley, G.L.3
  • 122
    • 0033593002 scopus 로고    scopus 로고
    • Isolated cleft palate in mice with a targeted mutation of the Lim Homeobox Gene 1hx8
    • Zhao Y, Guo YJ, Tomac AC et al. Isolated cleft palate in mice with a targeted mutation of the Lim Homeobox Gene 1hx8. Proc Natl Acad Sci USA 1999: 96 (26): 15002-15006.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , Issue.26 , pp. 15002-15006
    • Zhao, Y.1    Guo, Y.J.2    Tomac, A.C.3


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