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Volumn 10, Issue 1, 2010, Pages 15-26

Clostridial spores to treat solid tumours - Potential for a new therapeutic modality

Author keywords

Clostridial spores; ClosTron; Hypoxia; Necrosis; Oncolysis; Tumour therapy

Indexed keywords

BACTERIAL VECTOR; DOXORUBICIN;

EID: 77950823901     PISSN: 15665232     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (11)

References (68)
  • 1
    • 5044239737 scopus 로고    scopus 로고
    • Microenvironmental adaptation of experimental tumours to chronic vs acute hypoxia
    • Thews O, Wolloscheck T, Dillenburg W, et al. Microenvironmen- tal adaptation of experimental tumours to chronic vs acute hypoxia. Br J Cancer 2004; 91(6): 1181-1189
    • (2004) Br J Cancer , vol.91 , Issue.6 , pp. 1181-1189
    • Thews, O.1    Wolloscheck, T.2    Dillenburg, W.3
  • 2
    • 0025807618 scopus 로고
    • Oxygenation of human tumors: Evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements
    • Vaupel P, Schlenger K, Knoop C, Hockel M. Oxygenation of human tumors: evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements. Cancer Res 1991; 51(12): 3316-3322
    • (1991) Cancer Res , vol.51 , Issue.12 , pp. 3316-3322
    • Vaupel, P.1    Schlenger, K.2    Knoop, C.3    Hockel, M.4
  • 3
    • 0037847453 scopus 로고    scopus 로고
    • Measurements of hypoxia using pimonidazole and polarographic oxygen-sensitive electrodes in human cervix carcinomas
    • Nordsmark M, Loncaster J, Aquino-Parsons C, et al. Measurements of hypoxia using pimonidazole and polarographic oxygen-sensitive electrodes in human cervix carcinomas. Radiother Oncol 2003; 67(1): 35-44.
    • (2003) Radiother Oncol , vol.67 , Issue.1 , pp. 35-44
    • Nordsmark, M.1    Loncaster, J.2    Aquino-Parsons, C.3
  • 4
    • 34547121206 scopus 로고    scopus 로고
    • Hypoxia in cancer: Significance and impact on clinical outcome
    • Vaupel P, Mayer A. Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev 2007; 26(2): 225-239
    • (2007) Cancer Metastasis Rev , vol.26 , Issue.2 , pp. 225-239
    • Vaupel, P.1    Mayer, A.2
  • 5
    • 0026846928 scopus 로고
    • The role of angiogenesis in tumor growth
    • Folkman J. The role of angiogenesis in tumor growth. Semin Cancer Biol 1992; 3(2): 65-71.
    • (1992) Semin Cancer Biol , vol.3 , Issue.2 , pp. 65-71
    • Folkman, J.1
  • 6
    • 0036173591 scopus 로고    scopus 로고
    • Hypoxia as a target for combined modality treatments
    • Wouters BG, Weppler SA, Koritzinsky M, et al. Hypoxia as a target for combined modality treatments. Eur J Cancer 2002; 38(2): 240-257
    • (2002) Eur J Cancer , vol.38 , Issue.2 , pp. 240-257
    • Wouters, B.G.1    Weppler, S.A.2    Koritzinsky, M.3
  • 8
    • 33748165246 scopus 로고    scopus 로고
    • The prognostic value of pimonidazole and tumour pO2 in human cervix carcinomas after radiation therapy: A prospective international multi-center study
    • Nordsmark M, Loncaster J, Aquino-Parsons C, et al. The prognostic value of pimonidazole and tumour pO2 in human cervix carcinomas after radiation therapy: a prospective international multi-center study. Radiother Oncol 2006; 80(2): 123-131
    • (2006) Radiother Oncol , vol.80 , Issue.2 , pp. 123-131
    • Nordsmark, M.1    Loncaster, J.2    Aquino-Parsons, C.3
  • 9
    • 21844455567 scopus 로고    scopus 로고
    • Hypoxia in head and neck cancer: How much, how important?
    • Janssen HL, Haustermans KM, Balm AJ, Begg AC. Hypoxia in head and neck cancer: how much, how important? Head Neck 2005; 27(7): 622-638
    • (2005) Head Neck , vol.27 , Issue.7 , pp. 622-638
    • Janssen, H.L.1    Haustermans, K.M.2    Balm, A.J.3    Begg, A.C.4
  • 10
    • 0037480606 scopus 로고    scopus 로고
    • Hypoxic cervical cancers with low apoptotic index are highly aggressive
    • Hockel M, Schlenger K, Hockel S, Vaupel P. Hypoxic cervical cancers with low apoptotic index are highly aggressive. Cancer Res 1999; 59(18): 4525-4528
    • (1999) Cancer Res , vol.59 , Issue.18 , pp. 4525-4528
    • Hockel, M.1    Schlenger, K.2    Hockel, S.3    Vaupel, P.4
  • 11
    • 0030025773 scopus 로고    scopus 로고
    • Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
    • Graeber TG, Osmanian C, Jacks T, et al. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature 1996; 379(6560): 88-91.
    • (1996) Nature , vol.379 , Issue.6560 , pp. 88-91
    • Graeber, T.G.1    Osmanian, C.2    Jacks, T.3
  • 12
    • 1642565876 scopus 로고    scopus 로고
    • Tumor hypoxia and malignant progression
    • Vaupel P, Mayer A, Hockel M. Tumor hypoxia and malignant progression. Methods Enzymol 2004; 381: 335-354
    • (2004) Methods Enzymol , vol.381 , pp. 335-354
    • Vaupel, P.1    Mayer, A.2    Hockel, M.3
  • 13
    • 0032144380 scopus 로고    scopus 로고
    • Colonisation of Clostridium in the body is restricted to hypoxic and necrotic areas of tumours
    • Lambin P, Theys J, Landuyt W, et al. Colonisation of Clostridium in the body is restricted to hypoxic and necrotic areas of tumours. Anaerobe 1998; 4(4): 183-188
    • (1998) Anaerobe , vol.4 , Issue.4 , pp. 183-188
    • Lambin, P.1    Theys, J.2    Landuyt, W.3
  • 14
    • 0030865697 scopus 로고    scopus 로고
    • Anaerobic bacteria as a gene delivery system that is controlled by the tumor microenvi-ronment
    • Lemmon MJ, van Zijl P, Fox ME, et al. Anaerobic bacteria as a gene delivery system that is controlled by the tumor microenvi- ronment. Gene Ther 1997; 4(8): 791-796
    • (1997) Gene Ther , vol.4 , Issue.8 , pp. 791-796
    • Lemmon, M.J.1    Van Zijl, P.2    Fox, M.E.3
  • 15
    • 1842613536 scopus 로고    scopus 로고
    • Clostridia in cancer therapy
    • Minton NP. Clostridia in cancer therapy. Nat Rev Microbiol 2003;1(3): 237-242
    • (2003) Nat Rev Microbiol , vol.1 , Issue.3 , pp. 237-242
    • Minton, N.P.1
  • 17
    • 0035909908 scopus 로고    scopus 로고
    • Combination bacteriolytic therapy for the treatment of experimental tumors
    • USA
    • Dang LH, Bettegowda C, Huso DL, Kinzler KW, Vogelstein B. Combination bacteriolytic therapy for the treatment of experimental tumors. Proc Natl Acad Sci USA 2001; 98(26): 15155-15160
    • (2001) Proc Natl Acad Sci , vol.98 , Issue.26 , pp. 15155-15160
    • Dang, L.H.1    Bettegowda, C.2    Huso, D.L.3    Kinzler, K.W.4    Vogelstein, B.5
  • 18
    • 85047697737 scopus 로고    scopus 로고
    • Anticancer efficacy of systemically delivered anaerobic bacteria as gene therapy vectors targeting tumor hypoxia/necrosis
    • Liu SC, Minton NP, Giaccia AJ, Brown JM. Anticancer efficacy of systemically delivered anaerobic bacteria as gene therapy vectors targeting tumor hypoxia/necrosis. Gene Ther 2002; 9(4): 291-296
    • (2002) Gene Ther , vol.9 , Issue.4 , pp. 291-296
    • Liu, S.C.1    Minton, N.P.2    Giaccia, A.J.3    Brown, J.M.4
  • 19
    • 53249149260 scopus 로고    scopus 로고
    • A genetically enhanced anaerobic bacterium for oncopathic therapy of pancreatic cancer
    • Li Z, Fallon J, Mandeli J, Wetmur J, Woo SL. A genetically enhanced anaerobic bacterium for oncopathic therapy of pancreatic cancer. J Natl Cancer Inst 2008; 100(19): 1389-1400
    • (2008) J Natl Cancer Inst , vol.100 , Issue.19 , pp. 1389-1400
    • Li, Z.1    Fallon, J.2    Mandeli, J.3    Wetmur, J.4    Woo, S.L.5
  • 20
    • 34347246680 scopus 로고    scopus 로고
    • Potential and limitations of bacterial-mediated cancer therapy
    • Mengesha A, Dubois L, Chiu RK, et al. Potential and limitations of bacterial-mediated cancer therapy. Front Biosci 2007; 12: 3880-3891
    • (2007) Front Biosci , vol.12 , pp. 3880-3891
    • Mengesha, A.1    Dubois, L.2    Chiu, R.K.3
  • 21
    • 0000775441 scopus 로고
    • Oncolysis by Clostridia. I: Activity of clostridium butyricum (M-55) and other nonpathogenic clostridia against the ehrlich carcinoma
    • Moese JR, Moese G. Oncolysis by Clostridia. I: activity of clostridium butyricum (M-55) and other nonpathogenic clostridia against the ehrlich carcinoma. Cancer Res 1964; 24: 212-216
    • (1964) Cancer Res , Issue.24 , pp. 212-216
    • Moese, J.R.1    Moese, G.2
  • 22
    • 0014197817 scopus 로고
    • Oncolysis of malignant tumors through the M 55 clostridium strain
    • Mose JR, Mose G, Propst A, Heppner F. Oncolysis of malignant tumors through the M 55 clostridium strain. II: Med Klin 1967; 62(6): 220-225
    • (1967) II: Med Klin , vol.62 , Issue.6 , pp. 220-225
    • Mose, J.R.1    Mose, G.2    Propst, A.3    Heppner, F.4
  • 23
    • 38649109315 scopus 로고    scopus 로고
    • The tumour- Clostridium phenomenon: 50 years of developmental research (Review)
    • Schmidt W, Fabricius EM, Schneeweiss U. The tumour- Clostridium phenomenon: 50 years of developmental research (Review). Int J Oncol 2006; 29(6): 1479-1492
    • (2006) Int J Oncol , vol.29 , Issue.6 , pp. 1479-1492
    • Schmidt, W.1    Fabricius, E.M.2    Schneeweiss, U.3
  • 24
    • 0001448008 scopus 로고
    • Oncolysis by clostridia. V: Transplanted tumors of the hamster
    • Engelbart K, Gericke D. Oncolysis by Clostridia. V: transplanted Tumors of the hamster. Cancer Res 1964; 24: 239-242
    • (1964) Cancer Res , Issue.24 , pp. 239-242
    • Engelbart, K.1    Gericke, D.2
  • 25
    • 78651160643 scopus 로고
    • Oncolysis by Clostridia Iv: Effect of nonpathogenic clostridial spores in normal and pathological tissues
    • Thiele EH, Arison RN, Boxer GE. Oncolysis by Clostridia. Iv: effect of nonpathogenic clostridial spores in normal and pathological tissues. Cancer Res 1964; 24: 234-238
    • (1964) Cancer Res , vol.24 , pp. 234-238
    • Thiele, E.H.1    Arison, R.N.2    Boxer, G.E.3
  • 26
    • 78651152166 scopus 로고
    • Oncolysis by clostridia Iii: Effects of clostridia and chemotherapeutic agents on rodent tumors
    • Thiele EH, Arison RN, Boxer GE. Oncolysis by Clostridia. Iii: effects of clostridia and chemotherapeutic agents on rodent tumors. Cancer Res 1964; 24: 222-233
    • (1964) Cancer Res , vol.24 , pp. 222-233
    • Thiele, E.H.1    Arison, R.N.2    Boxer, G.E.3
  • 27
    • 0018098489 scopus 로고
    • The liquefaction (oncolysis) of malignant gliomas by a non pathogenic Clostridium
    • Wien
    • Heppner F, Mose JR. The liquefaction (oncolysis) of malignant gliomas by a non pathogenic Clostridium. Acta Neurochir (Wien) 1978; 42(1-2): 123-125
    • (1978) Acta Neurochir , vol.42 , Issue.1-2 , pp. 123-125
    • Heppner, F.1    Mose, J.R.2
  • 28
    • 0014002979 scopus 로고
    • Oncolysis of malignant gliomas through apathogenic clostridia (strain "M 55")
    • Heppner F, Mose JR. Oncolysis of malignant gliomas through apathogenic clostridia (strain "M 55"). Zentralbl Neurochir 1966;27(4):183-192
    • (1966) Zentralbl Neurochir , vol.27 , Issue.4 , pp. 183-192
    • Heppner, F.1    Mose, J.R.2
  • 29
    • 0028844617 scopus 로고
    • Chemotherapeutic tumour targeting using clostridial spores
    • Minton NP, Mauchline ML, Lemmon MJ, et al. Chemotherapeutic tumour targeting using clostridial spores. FEMS Microbiol Rev 1995; 17(3): 357-364
    • (1995) FEMS Microbiol Rev , vol.17 , Issue.3 , pp. 357-364
    • Minton, N.P.1    Mauchline, M.L.2    Lemmon, M.J.3
  • 30
    • 37049011374 scopus 로고    scopus 로고
    • Bacterial targeted tumour therapy-dawn of a new era
    • Wei MQ, Mengesha A, Good D, Anne J. Bacterial targeted tumour therapy-dawn of a new era. Cancer Lett 2008; 259(1): 16-27.
    • (2008) Cancer Lett , vol.259 , Issue.1 , pp. 16-27
    • Wei, M.Q.1    Mengesha, A.2    Good, D.3    Anne, J.4
  • 31
    • 33750480202 scopus 로고    scopus 로고
    • Repeated cycles of Clos-tridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo
    • Theys J, Pennington O, Dubois L, et al. Repeated cycles of Clos-tridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo. Br J Cancer 2006; 95(9): 1212-1219
    • (2006) Br J Cancer , vol.95 , Issue.9 , pp. 1212-1219
    • Theys, J.1    Pennington, O.2    Dubois, L.3
  • 32
    • 10744232132 scopus 로고    scopus 로고
    • Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria
    • USA
    • Bettegowda C, Dang LH, Abrams R, et al. Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria. Proc Natl Acad Sci USA 2003; 100(25): 15083-15088
    • (2003) Proc Natl Acad Sci , vol.100 , Issue.25 , pp. 15083-15088
    • Bettegowda, C.1    Dang, L.H.2    Abrams, R.3
  • 33
    • 33751586094 scopus 로고    scopus 로고
    • A bacterial protein enhances the release and efficacy of liposomal cancer drugs
    • Cheong I, Huang X, Bettegowda C, et al. A bacterial protein enhances the release and efficacy of liposomal cancer drugs. Science 2006; 314(5803): 1308-1311
    • (2006) Science , vol.314 , Issue.5803 , pp. 1308-1311
    • Cheong, I.1    Huang, X.2    Bettegowda, C.3
  • 34
    • 0642285013 scopus 로고    scopus 로고
    • Tumor-specific gene delivery using genetically engineered bacteria
    • Theys J, Barbe S, Landuyt W, et al. Tumor-specific gene delivery using genetically engineered bacteria. Curr Gene Ther 2003; 3(3):207-221
    • (2003) Curr Gene Ther , vol.3 , Issue.3 , pp. 207-221
    • Theys, J.1    Barbe, S.2    Landuyt, W.3
  • 35
    • 27944440150 scopus 로고    scopus 로고
    • Pharmacologic and toxicologic evaluation of C. novyi-NT spores
    • Diaz LA, Jr, Cheong I, Foss CA, et al. Pharmacologic and toxi- cologic evaluation of C. novyi-NT spores. Toxicol Sci 2005; 88(2):562-575
    • (2005) Toxicol Sci , vol.88 , Issue.2 , pp. 562-575
    • Diaz, L.A.1    Jr Cheong, I.2    Foss, C.A.3
  • 36
    • 17544397865 scopus 로고    scopus 로고
    • Vascular targeting of solid tumours: A major 'inverse' volume-response relationship following combretastatin A-4 phosphate treatment of rat rhabdomyo-sarcomas
    • Landuyt W, Verdoes O, Darius DO, et al. Vascular targeting of solid tumours: a major 'inverse' volume-response relationship following combretastatin A-4 phosphate treatment of rat rhabdomyo-sarcomas. Eur J Cancer 2000; 36(14): 1833-1843.
    • (2000) Eur J Cancer , Issue.36 , pp. 14
    • Landuyt, W.1    Verdoes, O.2    Darius, D.O.3
  • 37
    • 0035023209 scopus 로고    scopus 로고
    • Specific targeting of cytosine deaminase to solid tumors by engineered Clostridium acetobutylicum
    • Theys J, Landuyt W, Nuyts S, et al. Specific targeting of cytosine deaminase to solid tumors by engineered Clostridium acetobutylicum. Cancer Gene Ther 2001; 8(4): 294-297
    • (2001) Cancer Gene Ther , vol.8 , Issue.4 , pp. 294-297
    • Theys, J.1    Landuyt, W.2    Nuyts, S.3
  • 38
    • 18144385828 scopus 로고    scopus 로고
    • Secretory production of biologically active rat interleukin-2 by Clostridium acetobutylicum DSM792 as a tool for anti-tumor treatment
    • Barbe S, Van Mellaert L, Theys J, et al. Secretory production of biologically active rat interleukin-2 by Clostridium acetobutylicum DSM792 as a tool for anti-tumor treatment. FEMS Microbiol Lett 2005; 246(1): 67-73.
    • (2005) FEMS Microbiol Lett , vol.246 , Issue.1 , pp. 67-73
    • Barbe, S.1    Van Mellaert, L.2    Theys, J.3
  • 39
    • 54249167548 scopus 로고    scopus 로고
    • Optimized clostridium-directed enzyme prodrug therapy improves the antitumor activity of the novel DNA cross-linking agent PR- 104
    • Liu SC, Ahn GO, Kioi M, Dorie MJ, Patterson AV, Brown JM. Optimized clostridium-directed enzyme prodrug therapy improves the antitumor activity of the novel DNA cross-linking agent PR- 104. Cancer Res 2008; 68(19): 7995-8003.
    • (2008) Cancer Res , vol.68 , Issue.19 , pp. 7995-8003
    • Liu, S.C.1    Ahn, G.O.2    Kioi, M.3    Dorie, M.J.4    Patterson, A.V.5    Brown, J.M.6
  • 40
    • 73349090587 scopus 로고    scopus 로고
    • Bystander or no bystander for gene directed enzyme prodrug therapy
    • Dachs GU, Hunt MA, Syddall S, Singleton DC, Patterson AV. Bystander or no bystander for gene directed enzyme prodrug therapy. Molecules 2009; 14(11): 4517-4545
    • (2009) Molecules , vol.14 , Issue.11 , pp. 4517-4545
    • Dachs, G.U.1    Hunt, M.A.2    Syddall, S.3    Singleton, D.C.4    Patterson, A.V.5
  • 41
    • 77950795423 scopus 로고    scopus 로고
    • Gene-directed enzyme prodrug therapy for cancer: A glimpse into the future
    • Both GW. Gene-directed enzyme prodrug therapy for cancer: a glimpse into the future. Discov Med 2009; 8(42): 97-103.
    • (2009) Discov Med , vol.8 , Issue.42 , pp. 97-103
    • Both, G.W.1
  • 42
    • 68649100167 scopus 로고    scopus 로고
    • Recent progress in gene-directed enzyme prodrug therapy: An emerging cancer treatment
    • Both GW. Recent progress in gene-directed enzyme prodrug therapy: an emerging cancer treatment. Curr Opin Mol Ther 2009;11(4): 421-432
    • (2009) Curr Opin Mol Ther , vol.11 , Issue.4 , pp. 421-432
    • Both, G.W.1
  • 43
    • 33845409424 scopus 로고    scopus 로고
    • Viral vectors for gene-directed enzyme prodrug therapy
    • Schepelmann S, Springer CJ. Viral vectors for gene-directed enzyme prodrug therapy. Curr Gene Ther 2006; 6(6): 647-670
    • (2006) Curr Gene Ther , vol.6 , Issue.6 , pp. 647-670
    • Schepelmann, S.1    Springer, C.J.2
  • 44
    • 0029932035 scopus 로고    scopus 로고
    • Anaerobic bacteria as a delivery system for cancer gene therapy in vitro activation of 5-fluorocytosine by genetically engineered clostridia
    • Fox ME, Lemmon MJ, Mauchline ML, et al. Anaerobic bacteria as a delivery system for cancer gene therapy: in vitro activation of 5-fluorocytosine by genetically engineered clostridia. Gene Ther 1996; 3(2): 173-178
    • (1996) Gene Ther , vol.3 , Issue.2 , pp. 173-178
    • Fox, M.E.1    Lemmon, M.J.2    Mauchline, M.L.3
  • 45
    • 0032830180 scopus 로고    scopus 로고
    • Stable Escherichia coli-Clostridium acetobutylicum shuttle vector for secretion of murine tumor necrosis factor alpha
    • Theys J, Nuyts S, Landuyt W, et al. Stable Escherichia coli-Clostridium acetobutylicum shuttle vector for secretion of murine tumor necrosis factor alpha. Appl Environ Microbiol 1999; 65(10):4295-4300
    • (1999) Appl Environ Microbiol , vol.65 , Issue.10 , pp. 4295-4300
    • Theys, J.1    Nuyts, S.2    Landuyt, W.3
  • 46
    • 73249128368 scopus 로고    scopus 로고
    • Increasing sensitivity to radiotherapy and chemotherapy by using novel biological agents that alter the tumor microenvironment
    • Shinohara ET, Maity A. Increasing sensitivity to radiotherapy and chemotherapy by using novel biological agents that alter the tumor microenvironment. Curr Mol Med 2009; 9(9): 1034-1045
    • (2009) Curr Mol Med , vol.9 , Issue.9 , pp. 1034-1045
    • Shinohara, E.T.1    Maity, A.2
  • 47
    • 0035134791 scopus 로고    scopus 로고
    • Improvement of Clostridium tumour targeting vectors evaluated in rat rhabdomyosarcomas
    • Theys J, Landuyt W, Nuyts S, et al. Improvement of Clostridium tumour targeting vectors evaluated in rat rhabdomyosarcomas. FEMS Immunol Med Microbiol 2001; 30(1): 37-41.
    • (2001) FEMS Immunol Med Microbiol , vol.30 , Issue.1 , pp. 37-41
    • Theys, J.1    Landuyt, W.2    Nuyts, S.3
  • 48
    • 0036852191 scopus 로고    scopus 로고
    • Natural selection of tumor variants in the generation of "tumor escape" phenotypes
    • Khong HT, Restifo NP. Natural selection of tumor variants in the generation of "tumor escape" phenotypes. Nat Immunol 2002;3(11): 999-1005.
    • (2002) Nat Immunol , vol.3 , Issue.11 , pp. 999-1005
    • Khong, H.T.1    Restifo, N.P.2
  • 49
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn GP, Old LJ, Schreiber RD. The immunobiology of cancer immunosurveillance and immunoediting. Immunity 2004; 21(2):137-148
    • (2004) Immunity , vol.21 , Issue.2 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 50
    • 0036153123 scopus 로고    scopus 로고
    • Tumour escape from immune surveillance through dendritic cell inactivation
    • Vicari AP, Caux C, Trinchieri G. Tumour escape from immune surveillance through dendritic cell inactivation. Semin Cancer Biol 2002; 12(1): 33-42.
    • (2002) Semin Cancer Biol , vol.12 , Issue.1 , pp. 33-42
    • Vicari, A.P.1    Caux, C.2    Trinchieri, G.3
  • 51
    • 33748987908 scopus 로고    scopus 로고
    • Cancer despite immunosur-veillance: Immunoselection and immunosubversion
    • Zitvogel L, Tesniere A, Kroemer G. Cancer despite immunosur-veillance: immunoselection and immunosubversion. Nat Rev Immunol 2006; 6(10): 715-727
    • (2006) Nat Rev Immunol , vol.6 , Issue.10 , pp. 715-727
    • Zitvogel, L.1    Tesniere, A.2    Kroemer, G.3
  • 52
    • 31544446842 scopus 로고    scopus 로고
    • Radiofrequency thermal ablation of hepatocellular carcinoma liver nodules can activate and enhance tumor-specific T-cell responses
    • Zerbini A, Pilli M, Penna A, et al. Radiofrequency thermal ablation of hepatocellular carcinoma liver nodules can activate and enhance tumor-specific T-cell responses. Cancer Res 2006; 66(2): 1139-1146
    • (2006) Cancer Res , vol.66 , Issue.2 , pp. 1139-1146
    • Zerbini, A.1    Pilli, M.2    Penna, A.3
  • 54
    • 2542603749 scopus 로고    scopus 로고
    • In situ tumor ablation creates an antigen source for the generation of antitumor immunity
    • den Brok MH, Sutmuller RP, van der Voort R, et al. In situ tumor ablation creates an antigen source for the generation of antitumor immunity. Cancer Res 2004; 64(11): 4024-4029
    • (2004) Cancer Res , vol.64 , Issue.11 , pp. 4024-4029
    • Den Brok, M.H.1    Sutmuller, R.P.2    Van Der Voort, R.3
  • 55
    • 11144357779 scopus 로고    scopus 로고
    • Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells
    • Wang T, Niu G, Kortylewski M, et al. Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. Nat Med 2004; 10(1): 48-54.
    • (2004) Nat Med , vol.10 , Issue.1 , pp. 48-54
    • Wang, T.1    Niu, G.2    Kortylewski, M.3
  • 56
    • 30544448127 scopus 로고    scopus 로고
    • Triggering TLR signaling in vaccination
    • van Duin D, Medzhitov R, Shaw AC. Triggering TLR signaling in vaccination. Trends Immunol 2006; 27(1): 49-55.
    • (2006) Trends Immunol , vol.27 , Issue.1 , pp. 49-55
    • Van Duin, D.1    Medzhitov, R.2    Shaw, A.C.3
  • 57
    • 20944451617 scopus 로고    scopus 로고
    • Cancer immunotherapy based on killing of Salmonella-infected tumor cells
    • Avogadri F, Martinoli C, Petrovska L, et al. Cancer immunotherapy based on killing of Salmonella-infected tumor cells. Cancer Res 2005; 65(9): 3920-3927
    • (2005) Cancer Res , vol.65 , Issue.9 , pp. 3920-3927
    • Avogadri, F.1    Martinoli, C.2    Petrovska, L.3
  • 58
    • 50549093152 scopus 로고    scopus 로고
    • Intra-tumoral Salmonella typhimurium induces a systemic anti-tumor immune response that is directed by low-dose radiation to treat distal disease
    • Avogadri F, Mittal D, Saccheri F, et al. Intra-tumoral Salmonella typhimurium induces a systemic anti-tumor immune response that is directed by low-dose radiation to treat distal disease. Eur J Immunol 2008; 38(7): 1937-1947
    • (2008) Eur J Immunol , vol.38 , Issue.7 , pp. 1937-1947
    • Avogadri, F.1    Mittal, D.2    Saccheri, F.3
  • 59
    • 6344284114 scopus 로고    scopus 로고
    • Bacteriolytic therapy can generate a potent immune response against experimental tumors
    • USA
    • Agrawal N, Bettegowda C, Cheong I, et al. Bacteriolytic therapy can generate a potent immune response against experimental tumors. Proc Natl Acad Sci USA 2004; 101(42): 15172-15177
    • (2004) Proc Natl Acad Sci , vol.101 , Issue.42 , pp. 15172-15177
    • Agrawal, N.1    Bettegowda, C.2    Cheong, I.3
  • 61
    • 4944233187 scopus 로고    scopus 로고
    • Tumour lysis syndrome: New therapeutic strategies and classification
    • Cairo MS, Bishop M. Tumour lysis syndrome: new therapeutic strategies and classification. Br J Haematol 2004; 127(1): 3-11.
    • (2004) Br J Haematol , vol.127 , Issue.1 , pp. 3-11
    • Cairo, M.S.1    Bishop, M.2
  • 63
    • 0033854940 scopus 로고    scopus 로고
    • Simple and efficient method for heterologous expression of clostridial proteins
    • Zdanovsky AG, Zdanovskaia MV. Simple and efficient method for heterologous expression of clostridial proteins. Appl Environ Microbiol 2000; 66(8): 3166-3173
    • (2000) Appl Environ Microbiol , vol.66 , Issue.8 , pp. 3166-3173
    • Zdanovsky, A.G.1    Zdanovskaia, M.V.2
  • 64
    • 0024787893 scopus 로고
    • Expression of tetanus toxin fragment C in E. coli: High level expression by removing rare codons
    • Makoff AJ, Oxer MD, Romanos MA, Fairweather NF, Ballantine S. Expression of tetanus toxin fragment C in E. coli: high level expression by removing rare codons. Nucleic Acids Res 1989;17(24): 10191-10202
    • (1989) Nucleic Acids Res , vol.17 , Issue.24 , pp. 10191-10202
    • Makoff, A.J.1    Oxer, M.D.2    Romanos, M.A.3    Fairweather, N.F.4    Ballantine, S.5
  • 65
    • 70450265182 scopus 로고    scopus 로고
    • Overcoming codon-usage bias in heterologous protein expression in Streptococcus gordonii
    • Lee SF, Li YJ, Halperin SA. Overcoming codon-usage bias in heterologous protein expression in Streptococcus gordonii. Microbiology 2009; 155(Pt 11): 3581-3588
    • (2009) Microbiology , vol.155 , Issue.PART 11 , pp. 3581-3588
    • Lee, S.F.1    Li, Y.J.2    Halperin, S.A.3
  • 68
    • 71749102588 scopus 로고    scopus 로고
    • The ClosTron: Mutagenesis in Clostridium refined and streamlined
    • Heap JT, Kuehne SA, Ehsaan M, et al. The ClosTron: Mutagenesis in Clostridium refined and streamlined. J Microbiol Methods 2010; 80(1): 45-50.
    • (2010) J Microbiol Methods , vol.80 , Issue.1 , pp. 45-50
    • Heap, J.T.1    Kuehne, S.A.2    Ehsaan, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.