Elevated total cholesterol in severely depressed patients: Role in cardiovascular risk?

World Journal of Biological Psychiatry

Volumn 11, Issue 2 PART 2, 2010, Pages 321-328

  Das, Partha Pratim ^a   Malhotra, Savita ^a   Chakrabarti, Subho ^a   Sharma, Sadhna ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

BMI; Cardiovascular risk; Cholesterol; Depression

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; DISEASE SEVERITY; FEMALE; HUMAN; LIFESTYLE; LIPID ANALYSIS; MAJOR DEPRESSION; MALE;

ADULT; AGE FACTORS; ANALYSIS OF VARIANCE; CARDIOVASCULAR DISEASES; CASE-CONTROL STUDIES; CHOLESTEROL; DEPRESSIVE DISORDER; FEMALE; FOOD HABITS; HUMANS; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; MALE; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; REGRESSION ANALYSIS; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SEX FACTORS; STATISTICS, NONPARAMETRIC; TRIGLYCERIDES; YOUNG ADULT;

EID: 77950797766     PISSN: 15622975     EISSN: 18141412     Source Type: Journal    
DOI: 10.3109/15622970902960889     Document Type: Article

References (67)

1. Adlersberg D, Schaefer LE, Steinberg AG, Wang CI. 1956. Age, sex, serum lipids, and coronary atherosclerosis. J Am Med Assoc 162:618-622.
2. American Psychiatric Association, Rush JA. 2000. Handbook of psychiatric measures. Washington, DC: American Psychiatric Association.
3. American Psychiatric Association. 2000. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC: American Psychiatric Association.
4. Bajwa WK, Asnig GM, Sanderson WC, Irfan A, Praag HM. 1992. High cholesterol levels in patients with panic disorder. Am J Psychiatry 149:376-378.
5. Blazer DG, Burchett BB, Fillenbaum GG. 2002. APOE 4 and low cholesterol as risks for depression in a biracial elderly community sample. Am J Geriatr Psychiatry 10:515-520.
6. Brendt MC. 2003. Induction of platelet-Endothelial interactions in post-capillary venules in hypercholesterolemia: critical role of P-selectin. Arterioscler Thromb Vasc Biol 23:525-527.
7. Brown SL, Salive ME, Harris TB. 1994. Low cholesterol concentration and severe depressive symptoms in elderly people. Br Med J 308:28-32.
8. Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults. The evidence report. NIH publication no. 98-4083 September 1998. National Institutes of Health National Heart, Lung, and Blood Institute in cooperation with the National Institute of Diabetes and Digestive and Kidney Diseases.
9. Delva NJ, Matthews DR, Cohen PJ. 1996. Brain serotonin (5-HT) neuro-endocrine function in patients taking cholesterol-lowering drugs. Biol Psychiatry 39:100-106.
10. Engelberg H. 1992. Low serum cholesterol and suicide. Lancet 339:727-29.
11. Fava M, Abraham M, Pava J, Shuster J, Rosenbaum J. 1996. Cardiovascular risk factors in depression: The role of anxiety and anger attack. Psychosomatics 37:31-37.
12. First MB, Spitzer RL, Gibbon M, Williams JBW. 1997. The Structured Clinical Interview for DSM-IV Axis I Disorders-Clinician Version (SCID-CV). Washington, DC: American Psychiatric Press.
13. Fraguas R, Iosifescu DV, Bankier B, Perlis R, Clementi-Craven N, Alpert J, et al. 2007. Major depressive disorder with anger attacks and cardiovascular risk factors. Int J Psychiatry Med 37(1):99-111. (Pubitemid 47267403)
14. Freedman DS, Byers T, Barrett DH, Stroup NE, Eaker E, Monroe-Blum H. 1995. Plasma lipid levels and psychologic characteristics in men. Am J Epidemiol 141:507-517.
15. Gold PW, Drevets WC, Charney DS. 2002. New insights into the role of cortisol and the glucocorticoid receptor in severe depression. Biol Psychiatry 52:381-385.
16. Hamilton M. 1960. A rating scale for depression. J Neurol Neurosurg Psychiatr 23:56-62.
17. Harding TW, Climent CE, Diop M, Giel R, Ibrahim HH, Murthy RS, et al. 1983. The WHO collaborative study of strategies for extending mental health care. II: The development of new research methods. Am J Psychiatry 140:1474-1489.
18. Heron DS, Shinitzky M, Hershkowitz M, Samuel D. 1980. Lipid fluidity modulates the binding of serotonin to mouse brain membrane. Proc Natl Acad Sci USA 77:7463-7467. (Pubitemid 11131150)
19. Hillbrand M, Spitz RT. 1997. Introduction. In: Hillbrand M, Spitz RT, editors. Lipids, health and behavior. Washington, DC: American Psychological Association. pp 1-10.
20. Huang TL. 2005. Serum lipid profiles in major depression with clinical subtypes, suicide attempts and episodes. J Affect Disord 86:75-79.
21. Huang TL, Chen JF. 2004. Lipid and lipoprotein levels in depressive disorders with melancholic feature or atypical feature and dysthymia. Psychiatr Clin Neurosci 58:295-299.
22. Iribarren C, Reed DM, Wergowske G, Burchfiel CM, Dwyer JH. 1995. Serum cholesterol level and mortality due to suicide and trauma in the Honolulu heart program. Arch Intern Med 155:695-700.
23. Kaplan JR, Shively CA. 1994. Demonstration of an association among dietary cholesterol, central serotonergic activity, and social behavior in monkeys. Psychosom Med 56:479-484.
24. Lang S, Haits G. 1968. Blutserumcholesterinwerte bei depression. Deutsche Gesundheitswesen 23:82-84.
25. Lara N, Baker GB, Archer SL, Le Mellédo JM. 2003. Increased cholesterol levels during paroxetine administration in healthy men. J Clin Psychiatry 64(12):1455-1459.
26. Law M. 1996. Having too much evidence (depression, suicide, and low serum cholesterol). Br Med J 313:651-652.
27. Lindberg G, Rastam L, Gulberg B, Ekund GA. 1992. Low serum cholesterol concentration and short-term mortality from injuries in men and women. Br Med J 305:277-279.
28. Maes M, Delanghe J. 1994. Lower degree of esterification of serum cholesterol in depression: relevance for depression and suicide research. Acta Psychiatr Scand 90:252-258.
29. Maes M, Smith R. 1997. Lower serum high-density lipoprotein cholesterol in major depression and in depressed men with serious suicidal attempts: relationship with immune inflammatory markers. Acta Psychiatr Scand 95:212-221.
30. Mantel-Teeuwisse AK, Kloosterman JME, Maitland-van der Zee AH, Klungel OH, Porsius AJ, de Boer A. 2001. Drug-induced lipid changes: a review of the unintended effects of some commonly used drugs on serum lipid levels. Drug Saf 24: 443-456.
31. McCallum J, Simons L, Simons J, Friedlander Y. 1994. Low serum cholesterol is not associated with depression in the elderly: data from an Australian community study. Aust NZ J Med 24:561-564.
32. Morgan RE, Palinkas LA. 1993. Plasma cholesterol and depressive symptoms in older men. Lancet 341:75-78.
33. Muldoon MF, Kaplan JR. 1992. Effects of low fat diet on brain serotonergic responsivity in cynomolgus monkeys. Biol Psychiatry 31:739-742.
34. Muldoon MF, Manuck SB, Mathews KM. 1990. Lowering cholesterol concentrations and mortality: A quantitative review of primary prevention trials. Br Med J 301:309-314.
35. Möller-Leimkühler AM. 2007. Women with coronary artery disease and depression: A neglected risk group. World J Biol Psychiatry 9:92-101.
36. Mössner R, Mikova O, Koutsilieri E, Saoud M, Ehlis AC, Müller N, et al. 2007. Consensus paper of the WFSBP Task Force on Biological Markers: biological markers in depression. World J Biol Psychiatry 8(3):141-174.
37. Nakao M, Yano E. 2004. Relationship between major depression and high serum cholesterol in Japanese men. Tohoku J Exp Med 204:273-287. (Pubitemid 39618671)
38. Narayanan S. 2000. The preanalytic phase: An important component of laboratory medicine. Am J Clin Pathol 113:429-452.
39. Neaton JD, Blackburn JD, Jacobs D. 1992. Serum cholesterol level and mortality findings in for men screened in multiple risk factor intervention trial. Arch Intern Med 152:1490-1500.
40. Nicholas LM, Ford AL, Esposito SM, Ekstrom RD, Golden RN. 2003. The effects of mirtazapine on plasma lipid profiles in healthy subjects. J Clin Psychiatry 64(8):883-889.
41. Olusi SO, Fido AA. 1996. Serum lipid concentration in patients with major depressive disorder. Biol Psychiatry 40:1128-1131.
42. Ormiston T, Wolkowitz OM, Reus VI, Manfredi F. 2003. Behavioral implications of lowering cholesterol levels: a double-blind pilot study. Psychosomatics 44:412-414.
43. Oxenkrug GF, Branconnier RJ, Harto-Truax N, Cole JO. 1983. Is serum cholesterol a biological marker for major depressive disorder? Am J Psychiatry 140:7-8.
44. Papakostas GI, Ongur D, Iosifescu DV, Mischoulon D, Fava M. 2004. Cholesterol in mood and anxiety disorders: review of the literature and new hypotheses. Eur Neuropsychopharm 14:135-142.
45. Patient's statistical report for the years 1987-1991. 1993. Department of Psychiatry: PGIMER, Chandigarh.
46. Pekkanen J, Nissinen A, Punsar S, Karvonen MJ. 1989. Serum cholesterol and risk of accidental or violent death in a 25-year follow-up: The Finnish cohorts of the seven countries study. Arch Intern Med 149:1589-1591.
47. Rabe-Jablonska J, Poprawska I. 2000. Levels of serum total cholesterol and LDL cholesterol in patients with major depression in acute period and remission. Med Sci Monit 6:539-547.
48. Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 1994(344):1383-1389.
49. Ringo DL, Lindley SE, Faull KF, Faustman WO. 1994. Cholesterol and serotonin:seeking a possible link between blood cholesterol and CSF 5-HIAA. Biol Psychiatry 35:957-959.
50. Rush AJ, Pincus HA, First MB, Blacker E, et al. 2000. Handbook of psychiatric measures. Washington, DC: American Psychiatric Association. p 527.
51. Sarchiapone M, Camardese G, Roy A, Della Casa S, Satta MA, Gonzalez B, et al. 2001. Cholesterol and serotonin indices in depressed and suicidal patients. J Affect Disord 62:217-219.
52. Scanlon SM, Williams C, Schloss P. 2001. Membrane cholesterol modulates serotonin transporter activity. Biochemistry 40:10507-10513.
53. Severs NJ. 1992. Low serum cholesterol and suicide. Lancet 339:1001.
54. Singh K, Singh A. 2008. Changes in plasma fibrinogen, homocysteine and lipid profile in coronary artery disease patients of north Indian (Punjab) population. Biomedical Res 19(2) (accessed on 24 September 2008 from http://www. indmedica.com/journals.php).
55. Singh S, Venketesh S, Verma JS, Verma M, Lellamma CO, Goel RC. 2007. Paraoxonase (PON1) activity in North-West Indian Punjabis with coronary artery disease and type 2 diabetes mellitus. Indian J Med Res 125:783-787.
56. Singhal A. 2005. Mood disorders: epidemiology. In: Vyas JN, Nathawat SS, Gada M, Razdan V, editors. Essentials of postgraduate psychiatry. 1st ed. vol I. Hyderabad: Paras Publishers. p 503-511.
57. Snehalatha C, Viswanathan V, Ramachandran A. 2003. Cutoff values for normal anthropometric variables in Asian Indian adults. Diabetes Care 26(5):1380-1384.
58. Sonawalla S, Papakostas GI, Petersen T, Yeung AS, Smith M, Sickinger AH, et al. 2002. Elevated cholesterol levels in major depressive disorder associated with non response to fluoxetine treatment. Psychosomatics 43:310-316.
59. Steinberg HO, Bayazeed B, Hook G, Johnson A, Cronin J, Baron AD. 1997. Endothelial dysfunction is associated with Cholesterol levels in the high normal range in humans. Circulation 96:3287-3293.
60. Strandburg TE, Valvanne J, Tilvis RS. 1993. Serum lipids and depression. Lancet 342:433-434.
61. Tanskanen A, Vartiainen E, Tuomilehto J, Viinamäki H, Lehtonen J, Puska P. 2000. High serum cholesterol and risk of suicide. Am J Psychiatry 157:648-650.
62. Terao T, Iwata N, Kanazawa K, Takano T, Takahashi N, Hayashi T, et al. 2000. Low serum cholesterol levels and depressive state in human dock visitors. Acta Psychiatr Scand 101: 231-234.
63. Tsai SJ. 2007. Statins may enhance the proteolytic cleavage of proBDNF: Implications for the treatment of depression. Med Hypotheses 68:1296-1299.
64. Vogelzangs N, Suthers K, Ferrucci L, Simonsick EM, Ble A, Schrager M, et al. 2007. Hypercortisolemic depression is associated with the metabolic syndrome in late-life. Psychoneuroendocrinology 32(2):151-159.
65. Weidner G, Conner SL, Hollis JF, Conner WE. 1992. Improvements in hostility and depression in relation to dietary change and cholesterol lowering. Ann Intern Med 117:820-823.
66. WHO expert consultation. 2004. Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet 363:157-163.
67. Wulsin LR. 2004. Is depression a major risk factor for coronary disease? A systematic review of the epidemiologic evidence. Harv Rev Psychiatry 12:79-93.