A flexible bipartite coiled coil structure is required for the interaction of hexim1 with the P-TEFb subunit cyclin T1

Biochemistry

Volumn 49, Issue 14, 2010, Pages 3083-3091

  Schönichen, André ^a   Bigalke, Janna M ^a   Urbanke, Claus ^b   Grzesiek, Stephan ^c   Dames, Sonja A ^c   Geyer, Matthias ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL ULTRACENTRIFUGATION; BINDING DOMAIN; C-TERMINAL SEGMENTS; CELLULAR PROTEINS; COILED COIL; COILED-COIL DOMAINS; COILED-COIL STRUCTURE; CYCLIN T1; DIMER INTERFACE; ELONGATION FACTOR; HEAT DENATURATION; ISOTHERMAL TITRATION CALORIMETRY; N-TERMINALS; POINT MUTATIONS; POSITIVE TRANSCRIPTION; RNA POLYMERASE II;

CENTRIFUGATION; CIRCULAR DICHROISM SPECTROSCOPY; DICHROISM; PHOSPHORYLATION; RNA; STOICHIOMETRY; TRANSCRIPTION;

COMPLEXATION;

CYCLIN T1; HEXIM1; RNA POLYMERASE II; TRANSCRIPTION ELONGATION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL INTERACTION; CHEMICAL REACTION; CIRCULAR DICHROISM; DENATURATION; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; STOICHIOMETRY;

BINDING SITES; CIRCULAR DICHROISM; CROSS-LINKING REAGENTS; CYCLIN T; HUMANS; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RNA-BINDING PROTEINS; THERMODYNAMICS; TRANSITION TEMPERATURE; ULTRACENTRIFUGATION;

EID: 77950683267     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi902072f     Document Type: Article

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