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Volumn 30, Issue 2, 2010, Pages 645-651

Prognostic and predictive value of thymidylate synthase expression in primary colorectal cancer

Author keywords

Adjuvant 5 FU; Colorectal cancer; TS

Indexed keywords

FLUOROURACIL; THYMIDYLATE SYNTHASE;

EID: 77950535944     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (30)

References (31)
  • 1
    • 33749817947 scopus 로고    scopus 로고
    • The Colorectal Cancer Coalition: Reflections on the future
    • Johnston PG: The Colorectal Cancer Coalition: reflections on the future. Oncologist 11: 970-972, 2006.
    • (2006) Oncologist , vol.11 , pp. 970-972
    • Johnston, P.G.1
  • 2
    • 33749839931 scopus 로고    scopus 로고
    • New approaches to the adjuvant therapy of colon cancer
    • Benson AB, 3rd: New approaches to the adjuvant therapy of colon cancer. Oncologist 11: 973-980, 2006.
    • (2006) Oncologist , vol.11 , pp. 973-980
    • Benson III, A.B.1
  • 3
    • 0028956045 scopus 로고
    • Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: A final report
    • Moertel CG, Fleming TR, Macdonald JS et al: Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: a final report. Ann Intern Med 122: 321-326, 1995.
    • (1995) Ann Intern Med , vol.122 , pp. 321-326
    • Moertel, C.G.1    Fleming, T.R.2    Macdonald, J.S.3
  • 4
    • 1442290323 scopus 로고    scopus 로고
    • Thymidylate synthase expression and prognosis in colorectal cancer: A systematic review and meta-analysis
    • Popat S, Matakidou A and Houlston RS: Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis. J Clin Oncol 22: 529-536, 2004.
    • (2004) J Clin Oncol , vol.22 , pp. 529-536
    • Popat, S.1    Matakidou, A.2    Houlston, R.S.3
  • 5
    • 0028151449 scopus 로고
    • The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer
    • Johnston PG, Fisher ER, Rockette HE et al: The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer. J Clin Oncol 12: 2640-2647, 1994.
    • (1994) J Clin Oncol , vol.12 , pp. 2640-2647
    • Johnston, P.G.1    Fisher, E.R.2    Rockette, H.E.3
  • 6
    • 0141455146 scopus 로고    scopus 로고
    • Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression levels: Predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracil
    • Kornmann M, Schwabe W, Sander S et al: Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression levels: predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracil. Clin Cancer Res 9: 4116-4124, 2003.
    • (2003) Clin Cancer Res , vol.9 , pp. 4116-4124
    • Kornmann, M.1    Schwabe, W.2    Sander, S.3
  • 7
    • 26444472368 scopus 로고    scopus 로고
    • Prognostic and predictive value of the thymidylate synthase expression in patients with non-metastatic colorectal cancer
    • Aguiar S Jr, Lopes A, Soares FA et al: Prognostic and predictive value of the thymidylate synthase expression in patients with non-metastatic colorectal cancer. Eur J Surg Oncol 31: 863-868, 2005.
    • (2005) Eur J Surg Oncol , vol.31 , pp. 863-868
    • Aguiar Jr., S.1    Lopes, A.2    Soares, F.A.3
  • 8
    • 0031941249 scopus 로고    scopus 로고
    • A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance
    • Yamachika T, Nakanishi H, Inada K et al: A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance. Cancer 82: 70-77, 1998.
    • (1998) Cancer , vol.82 , pp. 70-77
    • Yamachika, T.1    Nakanishi, H.2    Inada, K.3
  • 9
    • 0036812810 scopus 로고    scopus 로고
    • Retrospective study on thymidylate synthase as a predictor of outcome and sensitivity to adjuvant chemotherapy in patients with curatively resected colorectal cancer
    • Sugiyama Y, Kato T, Nakazato H et al: Retrospective study on thymidylate synthase as a predictor of outcome and sensitivity to adjuvant chemotherapy in patients with curatively resected colorectal cancer. Anticancer Drugs 13: 931-938, 2002.
    • (2002) Anticancer Drugs , vol.13 , pp. 931-938
    • Sugiyama, Y.1    Kato, T.2    Nakazato, H.3
  • 10
    • 33845691987 scopus 로고    scopus 로고
    • The prognostic significance of thymidylate synthase and dihydropyrimidine dehydrogenase in colorectal cancer of 303 patients adjuvantly treated with 5-fluorouracil
    • Jensen SA, Vainer B and Sorensen JB: The prognostic significance of thymidylate synthase and dihydropyrimidine dehydrogenase in colorectal cancer of 303 patients adjuvantly treated with 5-fluorouracil. Int J Cancer 120: 694-701, 2007.
    • (2007) Int J Cancer , vol.120 , pp. 694-701
    • Jensen, S.A.1    Vainer, B.2    Sorensen, J.B.3
  • 11
    • 0033995850 scopus 로고    scopus 로고
    • Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method
    • Takenoue T, Nagawa H, Matsuda K et al: Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method. Ann Surg Oncol 7: 193-198, 2000.
    • (2000) Ann Surg Oncol , vol.7 , pp. 193-198
    • Takenoue, T.1    Nagawa, H.2    Matsuda, K.3
  • 12
    • 0032997572 scopus 로고    scopus 로고
    • Immunohistochemical quantitation of thymidylate synthase expression in colorectal cancer metastases predicts for clinical outcome to fluorouracil-based chemotherapy
    • Aschele C, Debernardis D, Casazza S et al: Immunohistochemical quantitation of thymidylate synthase expression in colorectal cancer metastases predicts for clinical outcome to fluorouracil-based chemotherapy. J Clin Oncol 17: 1760-1770, 1999.
    • (1999) J Clin Oncol , vol.17 , pp. 1760-1770
    • Aschele, C.1    Debernardis, D.2    Casazza, S.3
  • 13
    • 0030883708 scopus 로고    scopus 로고
    • Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin
    • Leichman CG, Lenz HJ, Leichman L et al: Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin. J Clin Oncol 15: 3223-3229, 1997.
    • (1997) J Clin Oncol , vol.15 , pp. 3223-3229
    • Leichman, C.G.1    Lenz, H.J.2    Leichman, L.3
  • 15
    • 0036534108 scopus 로고    scopus 로고
    • Thymidylate synthase expression in colorectal cancer: A prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapy
    • Edler D, Glimelius B, Hallstrom M et al: Thymidylate synthase expression in colorectal cancer: a prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapy. J Clin Oncol 20: 1721-1728, 2002.
    • (2002) J Clin Oncol , vol.20 , pp. 1721-1728
    • Edler, D.1    Glimelius, B.2    Hallstrom, M.3
  • 16
    • 28844482277 scopus 로고    scopus 로고
    • Adjuvant chemotherapy in colorectal cancer: A joint analysis of randomised trials by the Nordic Gastrointestinal Tumour Adjuvant Therapy Group
    • Glimelius B, Dahl O, Cedermark B et al: Adjuvant chemotherapy in colorectal cancer: a joint analysis of randomised trials by the Nordic Gastrointestinal Tumour Adjuvant Therapy Group. Acta Oncol 44: 904-912, 2005.
    • (2005) Acta Oncol , vol.44 , pp. 904-912
    • Glimelius, B.1    Dahl, O.2    Cedermark, B.3
  • 17
    • 0026335113 scopus 로고
    • Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissue
    • Johnston PG, Liang CM, Henry S et al: Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissue. Cancer Res 51: 6668-6676, 1991.
    • (1991) Cancer Res , vol.51 , pp. 6668-6676
    • Johnston, P.G.1    Liang, C.M.2    Henry, S.3
  • 18
    • 0036534002 scopus 로고    scopus 로고
    • Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer
    • Allegra CJ, Parr AL, Wold LE et al: Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer. J Clin Oncol 20: 1735-1743, 2002.
    • (2002) J Clin Oncol , vol.20 , pp. 1735-1743
    • Allegra, C.J.1    Parr, A.L.2    Wold, L.E.3
  • 19
    • 0037440051 scopus 로고    scopus 로고
    • Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: A National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study
    • Allegra CJ, Paik S, Colangelo LH et al: Prognostic value of thymidylate synthase, Ki-67, and p53 in patients with Dukes' B and C colon cancer: a National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project collaborative study. J Clin Oncol 21: 241-250, 2003.
    • (2003) J Clin Oncol , vol.21 , pp. 241-250
    • Allegra, C.J.1    Paik, S.2    Colangelo, L.H.3
  • 20
    • 0026560328 scopus 로고
    • Quantitation of thymidylate synthase, dihydrofolate reductase, and DT-diaphorase gene expression in human tumors using the polymerase chain reaction
    • Horikoshi T, Danenberg KD, Stadibauer TH et al: Quantitation of thymidylate synthase, dihydrofolate reductase, and DT-diaphorase gene expression in human tumors using the polymerase chain reaction. Cancer Res 52: 108-116, 1992.
    • (1992) Cancer Res , vol.52 , pp. 108-116
    • Horikoshi, T.1    Danenberg, K.D.2    Stadibauer, T.H.3
  • 21
    • 33644674355 scopus 로고    scopus 로고
    • Immunoprofiles of 11 biomarkers using tissue microarrays identify prognostic subgroups in colorectal cancer
    • Knösel T, Emde A, Schlüns K et al: Immunoprofiles of 11 biomarkers using tissue microarrays identify prognostic subgroups in colorectal cancer.Neoplasia 77(8): 741-747, 2005.
    • (2005) Neoplasia , vol.77 , Issue.8 , pp. 741-747
    • Knösel, T.1    Emde, A.2    Schlüns, K.3
  • 22
    • 0031426423 scopus 로고    scopus 로고
    • Immunohistochemical determination of thymidylate synthase in colorectal cancer - Methodological studies
    • Edler D, Blomgren H, Allegra CJ et al: Immunohistochemical determination of thymidylate synthase in colorectal cancer - methodological studies. Eur J Cancer 33: 2278-2281, 1997.
    • (1997) Eur J Cancer , vol.33 , pp. 2278-2281
    • Edler, D.1    Blomgren, H.2    Allegra, C.J.3
  • 23
    • 33845355719 scopus 로고    scopus 로고
    • A prospective, blinded analysis of thymidylate synthase and p53 expression as prognostic markers in the adjuvant treatment of colorectal cancer
    • Popat S, Chen Z, Zhao D et al: A prospective, blinded analysis of thymidylate synthase and p53 expression as prognostic markers in the adjuvant treatment of colorectal cancer. Ann Oncol 7: 1810-1817, 2006.
    • (2006) Ann Oncol , vol.7 , pp. 1810-1817
    • Popat, S.1    Chen, Z.2    Zhao, D.3
  • 24
    • 27144456276 scopus 로고    scopus 로고
    • Predictive value of thymidylate synthase and dihydropyrimidine dehydrogenase protein expression on survival in adjuvantly treated stage III colon cancer patients
    • Westra JL, Hollema H, Schaapveld M et al: Predictive value of thymidylate synthase and dihydropyrimidine dehydrogenase protein expression on survival in adjuvantly treated stage III colon cancer patients. Ann Oncol 16: 1646-1653, 2005.
    • (2005) Ann Oncol , vol.16 , pp. 1646-1653
    • Westra, J.L.1    Hollema, H.2    Schaapveld, M.3
  • 25
    • 43049134491 scopus 로고    scopus 로고
    • Prognostic significance of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase protein expression in colorectal cancer patients treated with or without 5-fluorouracil-based chemotherapy
    • Soong R, Shah N, Salto-Tellez M et al: Prognostic significance of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase protein expression in colorectal cancer patients treated with or without 5-fluorouracil-based chemotherapy. Ann Oncol 9: 915-919, 2008.
    • (2008) Ann Oncol , vol.9 , pp. 915-919
    • Soong, R.1    Shah, N.2    Salto-Tellez, M.3
  • 26
    • 0034000054 scopus 로고    scopus 로고
    • Characterization of dihydropyrimidine dehydrogenase on immunohistochemistry in colon carcinoma, and correlation between immunohistochemical score and protein level or messenger RNA expression
    • Takenoue T, Kitayama J, Takei Y et al: Characterization of dihydropyrimidine dehydrogenase on immunohistochemistry in colon carcinoma, and correlation between immunohistochemical score and protein level or messenger RNA expression. Ann Oncol 11: 273-279, 2000.
    • (2000) Ann Oncol , vol.11 , pp. 273-279
    • Takenoue, T.1    Kitayama, J.2    Takei, Y.3
  • 27
    • 0037130282 scopus 로고    scopus 로고
    • Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
    • Peters GJ, Backus HH, Freemantle S et al: Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism. Biochim Biophys Acta 1587: 194-205, 2002.
    • (2002) Biochim Biophys Acta , vol.1587 , pp. 194-205
    • Peters, G.J.1    Backus, H.H.2    Freemantle, S.3
  • 28
    • 0036796848 scopus 로고    scopus 로고
    • Thymidylate synthase protein expression and activity are related to the cell proliferation rate in human cancer cell lines
    • Derenzini M, Montanaro L, Trere D et al: Thymidylate synthase protein expression and activity are related to the cell proliferation rate in human cancer cell lines. Mol Pathol 55: 310-314, 2002.
    • (2002) Mol Pathol , vol.55 , pp. 310-314
    • Derenzini, M.1    Montanaro, L.2    Trere, D.3
  • 29
    • 42449115370 scopus 로고    scopus 로고
    • The role of molecular markers in predicting response to therapy in patients with colorectal cancer
    • Shankaran V, Wisinski KB, Mulcahy MF et al: The role of molecular markers in predicting response to therapy in patients with colorectal cancer. Mol Diagn Ther 12: 87-98, 2008.
    • (2008) Mol Diagn Ther , vol.12 , pp. 87-98
    • Shankaran, V.1    Wisinski, K.B.2    Mulcahy, M.F.3
  • 30
    • 34249881055 scopus 로고    scopus 로고
    • Tumour markers in colorectal cancer: European Group on Tumour Markers (EGTM) guidelines for clinical use
    • Duffy MJ, van Dalen A, Haglund C et al: Tumour markers in colorectal cancer: European Group on Tumour Markers (EGTM) guidelines for clinical use. Eur J Cancer 43: 1348-1360, 2007.
    • (2007) Eur J Cancer , vol.43 , pp. 1348-1360
    • Duffy, M.J.1    Van Dalen, A.2    Haglund, C.3
  • 31
    • 33846595479 scopus 로고    scopus 로고
    • ASCO 2006 update of recommendations for the use of tumor markers in gastrointestinal cancer
    • Locker GY, Hamilton S, Harris J et al: ASCO 2006 update of recommendations for the use of tumor markers in gastrointestinal cancer. J Clin Oncol 24: 5313-5327, 2006.
    • (2006) J Clin Oncol , vol.24 , pp. 5313-5327
    • Locker, G.Y.1    Hamilton, S.2    Harris, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.