메뉴 건너뛰기




Volumn 107, Issue 13, 2010, Pages 5875-5880

Huwe1 ubiquitin ligase is essential to synchronize neuronal and glial differentiation in the developing cerebellum

Author keywords

Cell migration; Development; HECT domain; Nervous system; Tumor suppressor

Indexed keywords

HUWE1 PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

EID: 77950531110     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0912874107     Document Type: Article
Times cited : (65)

References (41)
  • 1
    • 0034663583 scopus 로고    scopus 로고
    • Radial glia phenotype: Origin, regulation, and transdifferentiation
    • DOI 10.1002/1097-4547(20000815)61:4<357::AID-JNR1>3.0.CO;2-7
    • Chanas-Sacre G, Rogister B, Moonen G, Leprince P (2000) Radial glia phenotype: Origin, regulation, and transdifferentiation. J Neurosci Res 61:357-363. (Pubitemid 30620220)
    • (2000) Journal of Neuroscience Research , vol.61 , Issue.4 , pp. 357-363
    • Chanas-Sacre, G.1    Rogister, B.2    Moonen, G.3    Leprince, P.4
  • 2
    • 0036616280 scopus 로고    scopus 로고
    • Cytodifferentiation of Bergmann glia and its relationship with Purkinje cells
    • Yamada K, Watanabe M (2002) Cytodifferentiation of Bergmann glia and its relationship with Purkinje cells. Anat Sci Int 77:94-108.
    • (2002) Anat Sci Int , vol.77 , pp. 94-108
    • Yamada, K.1    Watanabe, M.2
  • 3
    • 68349116164 scopus 로고    scopus 로고
    • The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain
    • Zhao X, et al. (2009) The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain. Dev Cell 17:210-221.
    • (2009) Dev Cell , vol.17 , pp. 210-221
    • Zhao, X.1
  • 4
    • 0035170704 scopus 로고    scopus 로고
    • HGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo
    • DOI 10.1002/gene.10008
    • Zhuo L, et al. (2001) hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo. Genesis 31:85-94. (Pubitemid 33064319)
    • (2001) Genesis , vol.31 , Issue.2 , pp. 85-94
    • Zhuo, L.1    Theis, M.2    Alvarez-Maya, I.3    Brenner, M.4    Willecke, K.5    Messing, A.6
  • 5
    • 0034723714 scopus 로고    scopus 로고
    • Dynamic transformation of Bergmann glial fibers proceeds in correlation with dendritic outgrowth and synapse formation of cerebellar Purkinje cells
    • DOI 10.1002/(SICI)1096-9861(20000228)418:1<106::AID-CNE8>3.0.CO;2-N
    • Yamada K, et al. (2000) Dynamic transformation of Bergmann glial fibers proceeds in correlation with dendritic outgrowth and synapse formation of cerebellar Purkinje cells. J Comp Neurol 418:106-120. (Pubitemid 30090943)
    • (2000) Journal of Comparative Neurology , vol.418 , Issue.1 , pp. 106-120
    • Yamada, K.1    Fukaya, M.2    Shibata, T.3    Kurihara, H.4    Tanaka, K.5    Inoue, Y.6    Watanabe, M.7
  • 6
    • 0028956797 scopus 로고
    • Mechanisms of neural patterning and specification in the developing cerebellum
    • Hatten ME, Heintz N (1995) Mechanisms of neural patterning and specification in the developing cerebellum. Annu Rev Neurosci 18:385-408.
    • (1995) Annu Rev Neurosci , vol.18 , pp. 385-408
    • Hatten, M.E.1    Heintz, N.2
  • 7
    • 44649201561 scopus 로고    scopus 로고
    • The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein
    • Zhao X, et al. (2008) The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein. Nat Cell Biol 10:643-653.
    • (2008) Nat Cell Biol , vol.10 , pp. 643-653
    • Zhao, X.1
  • 8
    • 0037232580 scopus 로고    scopus 로고
    • Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors
    • Kenney AM, Cole MD, Rowitch DH (2003) Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors. Development 130:15-28.
    • (2003) Development , vol.130 , pp. 15-28
    • Kenney, A.M.1    Cole, M.D.2    Rowitch, D.H.3
  • 9
    • 0037108268 scopus 로고    scopus 로고
    • N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
    • Knoepfler PS, Cheng PF, Eisenman RN (2002) N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev 16:2699-2712.
    • (2002) Genes Dev , vol.16 , pp. 2699-2712
    • Knoepfler, P.S.1    Cheng, P.F.2    Eisenman, R.N.3
  • 10
    • 24144441250 scopus 로고    scopus 로고
    • The Cdk1 complex plays a prime role in regulating N-myc phosphorylation and turnover in neural precursors
    • DOI 10.1016/j.devcel.2005.07.014, PII S1534580705002947
    • Sjostrom SK, Finn G, Hahn WC, Rowitch DH, Kenney AM (2005) The Cdk1 complex plays a prime role in regulating N-myc phosphorylation and turnover in neural precursors. Dev Cell 9:327-338. (Pubitemid 41235803)
    • (2005) Developmental Cell , vol.9 , Issue.3 , pp. 327-338
    • Sjostrom, S.K.1    Finn, G.2    Hahn, W.C.3    Rowitch, D.H.4    Kenney, A.M.5
  • 11
    • 33645211987 scopus 로고    scopus 로고
    • Neural precursor cycling at sonic speed: N-Myc pedals, GSK-3 brakes
    • Knoepfler PS, Kenney AM (2006) Neural precursor cycling at sonic speed: N-Myc pedals, GSK-3 brakes. Cell Cycle 5:47-52.
    • (2006) Cell Cycle , vol.5 , pp. 47-52
    • Knoepfler, P.S.1    Kenney, A.M.2
  • 13
    • 45849153870 scopus 로고    scopus 로고
    • The HECT family of E3 ubiquitin ligases: Multiple players in cancer development
    • Bernassola F, Karin M, Ciechanover A, Melino G (2008) The HECT family of E3 ubiquitin ligases: Multiple players in cancer development. Cancer Cell 14:10-21.
    • (2008) Cancer Cell , vol.14 , pp. 10-21
    • Bernassola, F.1    Karin, M.2    Ciechanover, A.3    Melino, G.4
  • 14
    • 21244451434 scopus 로고    scopus 로고
    • ARF-BP1/mule is a critical mediator of the ARF tumor suppressor
    • DOI 10.1016/j.cell.2005.03.037, PII S0092867405003569
    • Chen D, et al. (2005) ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor. Cell 121:1071-1083. (Pubitemid 40884397)
    • (2005) Cell , vol.121 , Issue.7 , pp. 1071-1083
    • Chen, D.1    Kon, N.2    Li, M.3    Zhang, W.4    Qin, J.5    Gu, W.6
  • 15
    • 21244472965 scopus 로고    scopus 로고
    • Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis
    • DOI 10.1016/j.cell.2005.06.009, PII S0092867405005568
    • Zhong Q, Gao W, Du F, Wang X (2005) Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis. Cell 121:1085-1095. (Pubitemid 40884398)
    • (2005) Cell , vol.121 , Issue.7 , pp. 1085-1095
    • Zhong, Q.1    Gao, W.2    Du, F.3    Wang, X.4
  • 16
    • 54949149565 scopus 로고    scopus 로고
    • Apoptotic signaling by c-MYC
    • Hoffman B, Liebermann DA (2008) Apoptotic signaling by c-MYC. Oncogene 27: 6462-6472.
    • (2008) Oncogene , vol.27 , pp. 6462-6472
    • Hoffman, B.1    Liebermann, D.A.2
  • 18
    • 0033152450 scopus 로고    scopus 로고
    • Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons
    • Gleeson JG, Lin PT, Flanagan LA, Walsh CA (1999) Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons. Neuron 23:257-271.
    • (1999) Neuron , vol.23 , pp. 257-271
    • Gleeson, J.G.1    Lin, P.T.2    Flanagan, L.A.3    Walsh, C.A.4
  • 19
    • 0028299579 scopus 로고
    • Brain lipid-binding protein (BLBP): A novel signaling system in the developing mammalian CNS
    • DOI 10.1016/0896-6273(94)90341-7
    • Feng L, Hatten ME, Heintz N (1994) Brain lipid-binding protein (BLBP): A novel signaling system in the developing mammalian CNS. Neuron 12:895-908. (Pubitemid 24126249)
    • (1994) Neuron , vol.12 , Issue.4 , pp. 895-908
    • Feng, L.1    Hatten, M.E.2    Heintz, N.3
  • 20
    • 23844482662 scopus 로고    scopus 로고
    • Purkinje cell dendrites grow in alignment with Bergmann glia
    • DOI 10.1002/glia.20200
    • Lordkipanidze T, Dunaevsky A (2005) Purkinje cell dendrites grow in alignment with Bergmann glia. Glia 51:229-234. (Pubitemid 41297429)
    • (2005) GLIA , vol.51 , Issue.3 , pp. 229-234
    • Lordkipanidze, T.1    Dunaevsky, A.2
  • 21
    • 0015025916 scopus 로고
    • Neuron-glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electronmicroscopic study in Macacus Rhesus
    • Rakic P (1971) Neuron-glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electronmicroscopic study in Macacus Rhesus. J Comp Neurol 141:283-312.
    • (1971) J Comp Neurol , vol.141 , pp. 283-312
    • Rakic, P.1
  • 23
    • 0030750450 scopus 로고    scopus 로고
    • Neuregulin and erbB receptors play a critical role in neuronal migration
    • DOI 10.1016/S0896-6273(00)80346-3
    • Rio C, Rieff HI, Qi P, Khurana TS, Corfas G (1997) Neuregulin and erbB receptors play a critical role in neuronal migration. Neuron 19:39-50. (Pubitemid 27332992)
    • (1997) Neuron , vol.19 , Issue.1 , pp. 39-50
    • Rio, C.1    Rieff, H.I.2    Qi, P.3    Corfas, G.4
  • 24
    • 24944472303 scopus 로고    scopus 로고
    • DNER acts as a neuron-specific Notch ligand during Bergmann glial development
    • Eiraku M, et al. (2005) DNER acts as a neuron-specific Notch ligand during Bergmann glial development. Nat Neurosci 8:873-880.
    • (2005) Nat Neurosci , vol.8 , pp. 873-880
    • Eiraku, M.1
  • 25
    • 0036023380 scopus 로고    scopus 로고
    • Notch1 is required for neuronal and glial differentiation in the cerebellum
    • Lutolf S, Radtke F, Aguet M, Suter U, Taylor V (2002) Notch1 is required for neuronal and glial differentiation in the cerebellum. Development 129:373-385.
    • (2002) Development , vol.129 , pp. 373-385
    • Lutolf, S.1    Radtke, F.2    Aguet, M.3    Suter, U.4    Taylor, V.5
  • 26
    • 0037388308 scopus 로고    scopus 로고
    • Neuregulin 1-erbB2 signaling is required for the establishment of radial glia and their transformation into astrocytes in cerebral cortex
    • Schmid RS, et al. (2003) Neuregulin 1-erbB2 signaling is required for the establishment of radial glia and their transformation into astrocytes in cerebral cortex. Proc Natl Acad Sci USA 100:4251-4256.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4251-4256
    • Schmid, R.S.1
  • 27
    • 33644610874 scopus 로고    scopus 로고
    • Jagged1 ablation results in cerebellar granule cell migration defects and depletion of bergmann glia
    • DOI 10.1159/000090754
    • Weller M, Krautler N, Mantei N, Suter U, Taylor V (2006) Jagged1 ablation results in cerebellar granule cell migration defects and depletion of Bergmann glia. Dev Neurosci 28:70-80. (Pubitemid 43320052)
    • (2006) Developmental Neuroscience , vol.28 , Issue.1-2 , pp. 70-80
    • Weller, M.1    Krautler, N.2    Mantei, N.3    Suter, U.4    Taylor, V.5
  • 28
    • 0033697009 scopus 로고    scopus 로고
    • Radial glial identity is promoted by Notch1 signaling in the murine forebrain
    • Gaiano N, Nye JS, Fishell G (2000) Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron 26:395-404.
    • (2000) Neuron , vol.26 , pp. 395-404
    • Gaiano, N.1    Nye, J.S.2    Fishell, G.3
  • 29
    • 64049101537 scopus 로고    scopus 로고
    • Neuron-derived FGF9 is essential for scaffold formation of Bergmann radial fibers and migration of granule neurons in the cerebellum
    • Lin Y, et al. (2009) Neuron-derived FGF9 is essential for scaffold formation of Bergmann radial fibers and migration of granule neurons in the cerebellum. Dev Biol 329:44-54.
    • (2009) Dev Biol , vol.329 , pp. 44-54
    • Lin, Y.1
  • 30
    • 23844432216 scopus 로고    scopus 로고
    • PTEN deletion in Bergmann glia leads to premature differentiation and affects laminar organization
    • DOI 10.1242/dev.01891
    • Yue Q, et al. (2005) PTEN deletion in Bergmann glia leads to premature differentiation and affects laminar organization. Development 132:3281-3291. (Pubitemid 41167155)
    • (2005) Development , vol.132 , Issue.14 , pp. 3281-3291
    • Yue, Q.1    Groszer, M.2    Gil, J.S.3    Berk, A.J.4    Messing, A.5    Wu, H.6    Liu, X.7
  • 31
    • 0037115603 scopus 로고    scopus 로고
    • Development of mice expressing a single D-type cyclin
    • Ciemerych MA, et al. (2002) Development of mice expressing a single D-type cyclin. Genes Dev 16:3277-3289.
    • (2002) Genes Dev , vol.16 , pp. 3277-3289
    • Ciemerych, M.A.1
  • 32
    • 0038026135 scopus 로고    scopus 로고
    • Retinoic acid decreases targeting of p27 for degradation via an N-myc-dependent decrease in p27 phosphorylation and an N-myc-independent decrease in Skp2
    • DOI 10.1038/sj.cdd.4401125
    • Nakamura M, Matsuo T, Stauffer J, Neckers L, Thiele CJ (2003) Retinoic acid decreases targeting of p27 for degradation via an N-myc-dependent decrease in p27 phosphorylation and an N-myc-independent decrease in Skp2. Cell Death Differ 10:230-239. (Pubitemid 36553465)
    • (2003) Cell Death and Differentiation , vol.10 , Issue.2 , pp. 230-239
    • Nakamura, M.1    Matsuo, T.2    Stauffer, J.3    Neckers, L.4    Thiele, C.J.5
  • 34
    • 1642474000 scopus 로고    scopus 로고
    • Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors
    • Kenney AM, Widlund HR, Rowitch DH (2004) Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors. Development 131:217-228.
    • (2004) Development , vol.131 , pp. 217-228
    • Kenney, A.M.1    Widlund, H.R.2    Rowitch, D.H.3
  • 35
    • 2942738996 scopus 로고    scopus 로고
    • The hedgehog response network: Sensors, switches, and routers
    • DOI 10.1126/science.1098020
    • Lum L, Beachy PA (2004) The Hedgehog response network: Sensors, switches, and routers. Science 304:1755-1759. (Pubitemid 38787882)
    • (2004) Science , vol.304 , Issue.5678 , pp. 1755-1759
    • Lum, L.1    Beachy, P.A.2
  • 36
    • 34548306769 scopus 로고    scopus 로고
    • Patching the gaps in Hedgehog signalling
    • Rohatgi R, Scott MP (2007) Patching the gaps in Hedgehog signalling. Nat Cell Biol 9: 1005-1009.
    • (2007) Nat Cell Biol , vol.9 , pp. 1005-1009
    • Rohatgi, R.1    Scott, M.P.2
  • 37
    • 33645094926 scopus 로고    scopus 로고
    • N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medulloblastoma
    • Browd SR, et al. (2006) N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medulloblastoma. Cancer Res 66:2666-2672.
    • (2006) Cancer Res , vol.66 , pp. 2666-2672
    • Browd, S.R.1
  • 39
    • 58849084275 scopus 로고    scopus 로고
    • N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma
    • Kessler JD, et al. (2009) N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma. Genes Dev 23:157-170.
    • (2009) Genes Dev , vol.23 , pp. 157-170
    • Kessler, J.D.1
  • 40
    • 58649120079 scopus 로고    scopus 로고
    • Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma
    • Ayrault O, Zindy F, Rehg J, Sherr CJ, Roussel MF (2009) Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma. Mol Cancer Res 7:33-40.
    • (2009) Mol Cancer Res , vol.7 , pp. 33-40
    • Ayrault, O.1    Zindy, F.2    Rehg, J.3    Sherr, C.J.4    Roussel, M.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.