Induction of caspase-independent apoptotic-like cell death of mouse mammary tumor TA3Ha cells in vitro and reduction of their lethality in vivo by the novel chemotherapeutic agent GIT-27NO

Free Radical Biology and Medicine

Volumn 48, Issue 8, 2010, Pages 1090-1099

  Mijatovic, Sanja ^a   Maksimovic Ivanic, Danijela ^a   Timotijevic, Gordana ^b   Miljkovic, Djordje ^a   Donia, Marco ^c   Libra, Massimo ^c   Coco, Marinella ^c   McCubrey, James ^d   Al Abed, Yousef ^e   Korac, Aleksandra ^a   Stosic Grujicic, Stanislava ^a   Nicoletti, Ferdinando ^c  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b Belgrade University   (Serbia)

^c UNIVERSITY OF CATANIA   (Italy)

^d EAST CAROLINA UNIVERSITY   (United States)

^e University of Belgrade ^*  (United States)

Author keywords

Apoptosis; Bcl 2; Breast cancer; Caspases; Free radicals; GIT 27NO; Nitric oxide; P53; TA3Ha

Indexed keywords

3 PHENYL 4,5 DIHYDRO 5 ISOXAZOLEACETIC ACID; 3 PHENYL 4,5 DIHYDRO 5 ISOXAZOLEACETIC ACID NITRIC OXIDE; CASPASE; CASPASE 3; CASPASE 8; CASPASE 9; CISPLATIN; DNA; GIT 27NO; ISOXAZOLINE DERIVATIVE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PHOSPHATIDYLSERINE; PROTEIN BCL 2; PROTEIN P53; SERINE; UNCLASSIFIED DRUG; VGX 1027;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASCITES TUMOR; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL NUCLEUS; CELL VIABILITY; CHROMATIN CONDENSATION; CONTROLLED STUDY; DNA FRAGMENTATION; DOWN REGULATION; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GENETIC TRANSCRIPTION; IN VITRO STUDY; IN VIVO STUDY; LETHALITY; MOUSE; NONHUMAN; PERITONEUM CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ACETIC ACIDS; ANIMALS; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; DOWN-REGULATION; FEMALE; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; NITRIC OXIDE; OXADIAZOLES; OXAZOLES; PERITONEAL NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR SUPPRESSOR PROTEIN P53;

MUS;

EID: 77950517076     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.01.026     Document Type: Article

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