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Volumn 20, Issue 48, 2001, Pages 7120-7127
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Methylation in hMLH1 promoter interferes with its binding to transcription factor CBF and inhibits gene expression
a,b a,b a,b a,b |
Author keywords
Colorectal cancer; hMLH1 gene; Methylation; Transcription factor CBF
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Indexed keywords
CCAAT ENHANCER BINDING PROTEIN;
LUCIFERASE;
TRANSCRIPTION FACTOR;
TRANSCRIPTION FACTOR CBF;
UNCLASSIFIED DRUG;
ARTICLE;
COLORECTAL CANCER;
CPG ISLAND;
ENZYME ACTIVITY;
GENE EXPRESSION;
GENE SILENCING;
GENETIC TRANSCRIPTION;
GENETIC TRANSFECTION;
HUMAN;
HUMAN CELL;
METHYLATION;
MICROSATELLITE INSTABILITY;
PRIORITY JOURNAL;
PROMOTER REGION;
REPORTER GENE;
TRANSCRIPTION INITIATION;
ADENOCARCINOMA;
AZACITIDINE;
BINDING SITES;
CARRIER PROTEINS;
CCAAT-BINDING FACTOR;
COLORECTAL NEOPLASMS;
CPG ISLANDS;
DNA METHYLATION;
DNA, NEOPLASM;
ELECTROPHORESIS, POLYACRYLAMIDE GEL;
GENE EXPRESSION REGULATION;
GENE EXPRESSION REGULATION, NEOPLASTIC;
GENE SILENCING;
GENES, REPORTER;
HUMANS;
LUCIFERASES;
NEOPLASM PROTEINS;
NUCLEAR PROTEINS;
PROMOTER REGIONS (GENETICS);
PROTEIN BINDING;
RECOMBINANT FUSION PROTEINS;
TRANSCRIPTION, GENETIC;
TRANSFECTION;
TUMOR CELLS, CULTURED;
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EID: 0035950541
PISSN: 09509232
EISSN: None
Source Type: Journal
DOI: 10.1038/sj.onc.1204891 Document Type: Article |
Times cited : (71)
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References (32)
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