Identification of novel diagnostic serum biomarkers for chagas' disease in asymptomatic subjects by mass spectrometric profiling

Journal of Clinical Microbiology

Volumn 48, Issue 4, 2010, Pages 1139-1149

  Ndao, Momar ^a,b,l   Spithill, Terry W ^b,c   Caffrey, Rebecca ^d   Li, Hongshan ^e   Podust, Vladimir N ^f   Perichon, Regis ^g   Santamaria, Cynthia ^b   Ache, Alberto ^h   Duncan, Mark ⁱ   Powell, Malcolm R ^j,k   Ward, Brian J ^a,b  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c CHARLES STURT UNIVERSITY   (Australia)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e PALL CORPORATION   (United States)

^f CIPHERGEN BIOSYSTEMS INC   (United States)

^g Diagnostic Biomarker Evaluation Group   (United States)

^h Ministerio de Salud Y Desarrollo Social   (Venezuela)

ⁱ UNIVERSITY OF COLORADO   (United States)

^j WESTERN CAROLINA UNIVERSITY   (United States)

^k UNIVERSIDAD DEL VALLE   (Guatemala)

^l MONTREAL GENERAL HOSPITAL   (Canada)

more..

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; BIOLOGICAL MARKER; COMPLEMENT COMPONENT C3A; FIBRONECTIN; HIGH DENSITY LIPOPROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; PEPTIDE ANTIBODY;

ADOLESCENT; ADULT; AGED; ALGORITHM; ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; BLOOD EXAMINATION; BLOOD SAMPLING; CHAGAS DISEASE; CHILD; CLINICAL ASSESSMENT; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; ELECTROCARDIOGRAM; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; MAJOR CLINICAL STUDY; MASS SPECTROMETRY; PARASITOSIS; PRIORITY JOURNAL; PROTEIN MICROARRAY; SCHOOL CHILD; SENSITIVITY AND SPECIFICITY; TRYPANOSOMA CRUZI; WESTERN BLOTTING;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AMERICAS; ANIMALS; BIOLOGICAL MARKERS; CHAGAS DISEASE; CHILD; CLINICAL LABORATORY TECHNIQUES; FEMALE; HUMANS; MALE; MASS SPECTROMETRY; MIDDLE AGED; PROTEINS; SENSITIVITY AND SPECIFICITY; SERUM; TRYPANOSOMA CRUZI; YOUNG ADULT;

TRYPANOSOMA CRUZI;

EID: 77950483826     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.02207-09     Document Type: Article

References (54)

1. Antunes, C. M. F. 1999. Chagas disease (American trypanosomiasis): the epidemiology of Chagas disease, p. 351-369. In H. M. Gilles (ed.), Protozoal diseases. Arnold, London, United Kingdom.
2. Atwood, J. A., III, D. B. Weatherly, T. A. Minning, B. Bundy, C. Cavola, F. R. Opperdnes, R. Orlando, and R. L. Tarleton. 2005. The Trypanosoma cruzi proteome. Science 309: 473-476.
3. Baral, T. N., S. Magez, B. Stijlemans, K. Conrath, B. Vanhollebeke, E. Pays, S. Muyldermans, and P. De Baetselier. 2006. Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor. Nat. Med. 12: 580-584.
4. Beard, C. B., G. Pye, F. J. Steurer, R. Rodriguez, R. Campman, A. T. Peterson, J. Ramsey, R. A. Wirtz, and L. E. Robinson. 2003. Chagas disease in a domestic transmission cycle, Southern Texas, U.S.A. Emerg. Infect. Dis. 9: 103-105.
5. Berasain, P., C. Carmona, B. Frangione, J. J. Cazzulo, and F. Goni. 2003. Specific cleavage sites on human IgG subclasses by cruzipain, the major cysteine proteinase from Trypanosoma cruzi. Mol. Biochem. Parasitol. 130: 23-29.
6. Berrizbeitia, M., M. Ndao, J. Bubis, M. Gottschalk, A. Ache, S. Lacouture, M. Medina, and B. J. Ward. 2007. Field evaluation of four novel enzyme immunoassays for Chagas' disease in Venezuela blood banks: comparison of assays using fixed-epimastigotes, fixed-trypomastigotes or trypomastigote excreted-secreted antigens from two Trypanosoma cruzi strains. Transfus. Med. 16: 419-431.
7. Bradley, K. K., D. K. Bergman, J. P. Woods, J. M. Crutcher, and L. V. Kirchhoff. 2000. Prevalence of American trypanosomiasis (Chagas disease) among dogs in. Oklahoma. J. Am. Vet. Med. Assoc. 217: 1853-1857.
8. Breault, J. L., C. R. Goodall, and P. J. Fos. 2002. Data mining a diabetic data warehouse. Artif. Intell. Med. 26: 37-54.
9. Calvet, C. M., M. Meuser, D. Almeida, M. N. Meirelles, and M. C. Pereira. 2004. Trypanosoma crazi-cardiomyocyte interaction: role of fibronectin in the recognition process and extracellular matrix expression in vitro and in vivo. Exp. Parasitol. 107: 20-30.
10. Cano, R. C., E. R. Rubiolo, and N. O. Santamarina. 1985. Levels of apolipoproteins and cholesterol of low and high density lipoproteins in asymptomatic Chagas disease. Medicina 45: 269-272.
11. CDC. 2006. Chagas disease after organ transplantation - Los Angeles, California, 2006. Morb. Mortal. Wkly. Rep. 55: 798-800.
12. CDC. 2007. Blood donor screening for Chagas disease - United States, 2006-2007. Morb. Mortal. Wkly. Rep. 56: 141-143.
13. Combs, T. P., Nagajyothi, S. Mukherjee, C. J. G. de Almeida, L. A. Jelicks, W. Schubert, Y. Lin, D. S. Jayabalan, D. Zhao, V. L. Braunstein, S. Landskroner-Eiger, A. Cordero, S. M. Factor, L. M. Weiss, M. P. Lisanti, H. B. Tanowitz, and P. E. Seherer. 2005. The adipocyte as an important target cell for Trypanosoma cruzi infection. J. Biol. Chem. 280: 24085-24094.
14. Darde, V. M., M. G. Barderas, and F. Vivanco. 2007. Depletion of highabundance proteins in plasma by immunoafflnity subtraction for two-dimensional difference gel electrophoresis analysis. Methods Mol. Biol. 357: 351-364.
15. Davidson, W. S., and R. A. Silva. 2005. Apolipoprotein structural organization in high density lipoproteins: belts, bundles, hinges and hairpins. Curr. Opin. Lipidol. 16: 295-300.
16. Deckers, N., P. Dorny, K. Kanobana, J. Vercruysse, A. E. Gonzalez, B. Ward, and M. Ndao. 2008. Use of ProteinChip technology for identifying biomarkers of parasitic diseases: the example of porcine cysticercosis (Taenia solium). Exp. Parasitol. 120: 320-329.
17. de Oliveira, R. A., S. de Moraes, R. R. de Andrede, and M. R. Montenegra. 2000. Clinical and pathological assessment of 82 patients with cardiovascular diseases undergoing autopsy at the Hospital das Clinicas of the Faculdade de Medicina de Botucatu from 1988 to 1993. Arq. Bras. Cardiol. 75: 303-312.
18. Eberini, L, L. Calabresi, R. Wait, G. Tedeschi, A. Pirillo, L. Puglisi, C. R. Sirtori, and E. Gianazza. 2002. Macrophage metalloproteinases degrade high-density-lipoprotein-associated apolipoprotein A-I at both the N- and C-termini. Biochem. J. 362: 627-634.
19. Fenollar, F., A. Goncalves, B. Esterai, S. Azza, G. Habib, J. P. Borg, and D. Raoult. 2006. A. serum protein signature with high diagnostic value in bacterial endocarditis: results from a study based on surface-enhanced laser desorption/ionization time-of-flight mass spectrometry. J. Infect. Dis. 194: 1356-1366.
20. Garzotto, M., T. M. Beer, R. G. Hudson, L. Peters, Y. C. Hsieh, E. Barrera, T. Klein, and M. Mori. 2005. Improved detection of prostate cancer using classification and regression tree analysis. J. Clin. Oncol. 23: 4322-4329.
21. Gorlin, J., S. S. F. Rossmann, N. Hirschler, K. A. Nguyen, R. Gilcher, H. Fernandes, S. Alvey, P. Ajongwen, P. Contestable, and H. Warren. 2008. Evaluation of a new Trypanosoma cruzi antibody assay for blood donor screening. Transfusion 48: 531-540.
22. Grant, I. H., J. Gold, M. Wittner, H. B. Tanowitz, C. Nathan, K. Mayer, L. Reich, N. Wollner, L. Steinherz, and F. Ghavimi. 1989. Transfusion-associated acute Chagas disease acquired in the United States. Ann. Intern. Med. 111: 849-851.
23. Hess, K. R., M. C. Abbruzzese, R. Lenzi, M. N. Raber, and J. L. Abbruzzese. 1999. Classification and regression tree analysis of 1000 consecutive patients with, unknown primary carcinoma. Clin. Cancer Res. 5: 3403-3410.
24. Kirchhoff, L. V. 1993. American trypanosomiasis (Chagas' disease) - a tropical disease now in the United States. N. Engl. J. Med. 329: 639-644.
25. Lelby, D. A., M. H. Fucci, and R. J. Stumpf. 1999. Trypanosoma cruzi in a low- to moderate-risk blood donor population: seroprevalence and possible congenital transmission. Transfusion 39: 310-31.5.
26. Leiby, D. A., B. A. Lenes, M. A. Tibbals, and M. T. Tames-Olmedo. 1999. Prospective evaluation of a patient with Trypanosoma cruzi infection transmitted by transfusion. N. Engl. J. Med. 341: 1237-1239.
27. Linkov, F., A. Lisovich, Z. Yurkovetsky, A. Marrangoni, L. Velikokhatnaya, B. Nolen, M. Winans, W. Bigbee, J. Siegfried, A. Lokshln, and R. L. Ferris. 2007. Early detection of head and neck cancer: development of a novel screening tool using multiplexed immunobead-based biomarker profiling. Cancer Epidemiol. Biomarkers Prev. 16: 102-107.
28. Maguire, J. H. 2006. Chagas' disease - can we stop the deaths? N. Engl. J. Med. 355: 760-761.
29. Marino, A. P., A. A. Silva, R. T. Pinho, and J. Lannes-Vieira. 2003. Trypanosoma cruzi infection: a continuous invader-host cell cross talk with participation of extracellular matrix and adhesion and chemoattractant molecules. Braz. J. Med. Biol. Res. 36: 1121-1133.
30. Maurer, M., and E. von Stebut. 2004. Macrophage inflammatory protein-1. Int. J. Biochem. Cell Biol. 36: 1882-1886.
31. Meyers, C. D., and M. L. Kashyap. 2005. Pharmacologic augmentation of high-density lipoproteins: mechanisms of currently available and emerging therapies. Curr. Opin. Cardiol. 20: 307-312.
32. Mungai, M., G. Tegtmeier, M. Chamberland, and M. Parise. 2001. Transfusion-transmitted malaria in the United States from 1963 through 1999. N. Engl. J. Med. 344: 1973-1978.
33. Negrette, O. S., M. C. Mora, and M. A. Basombrio. 2005. High prevalence of congenital Trypanosoma cruzi infection and family clustering in Salta, Argentina. Pediatrics 115: e668-e672.
34. Newgard, C. D., R. J. Lewis, and B. T. Jolly. 2002. Use of out-of-hospital variables to predict severity of injury in pediatric patients involved in motor vehicle crashes. Ann. Emerg. Med. 39: 481-491.
35. Nickerson, P., P. Orr, M. L. Schroeder, L. Sekla, and J. B. Johnston. 1989. Transfusion-associated Trypanosoma cruzi infection in a non-endemic area. Ann. Intern. Med. 111: 851-853.
36. Ouaissi, M. A., J. Cornette, and A. Capron. 1986. Identification and isolation of Trypanosoma cruzi trypomastigote cell surface protein with properties expected of a fibronectin receptor. Mol. Biochem. Parasitol. 19: 201-211.
37. 37. Papadopoulos, M. C, P. M. Abel, D. Agranoff, A. Stich, E. Tarelli, B. A. Bell, T. Planche, A. Loosemore, S. Saadoun, P. Wilkins, and S. Krishna. 2004. A novel and accurate diagnostic test for human African trypanosomiasis. Lancet 363: 1358-1363. (Pubitemid 38529875)
38. Rioux, M. C, C. Carmona, D. Acosta, B. Ward, M. Ndao, B. F. Gibbs, H. P. Bennett, and T. W. Spithill. 2008. Discovery and validation of serum biomarkers expressed over the first twelve weeks of Fasciola hepatica infection in sheep. Int. J. Parasitol. 38: 123-136.
39. Sahu, A., and J. D. Lambris. 2001. Structure and biology of complement protein C3, a connecting link between innate and acquired immunity. Immunol. Rev. 180: 35-48.
40. Salomone, O. A., A. L. Basquiera, A. Sembaj, A. M. Aguerri, M. E. Reyes, M. Omelianuk, R. A. Fernandez, J. Enders, A. Palma, J. M. Barrai, and R. J. Madoery. 2003. Trypanosoma cruzi in persons without serologic evidence of disease, Argentina. Emerg. Infect. Dis. 9: 1558-1562.
41. Scheetz, L. J., J. Zhang, and J. Kolassa. 2009. Classification tree modeling to identify severe and moderate vehicular injuries in young and middle-aged adults. Artif. Intell. Med. 45: 1-10.
42. Schmunis, G. A., and J. R. Cruz. 2005. Safety of the blood supply in Latin America. Clin. Microbiol. Rev. 18: 12-29.
43. 43. Schwegler, E. E., L. Cazares, L. S. Steele, B. L. Adam, D. A. Johnson, O. J. Semmes, T. M. Block, J. A. Marrero, and R. R. Drake. 2005. SELDI-TOF MS profiling of serum for detection of the progression of chronic hepatitis C to hepatocellular carcinoma. Hepatology 41: 634-642. (Pubitemid 40289513)
44. Statistics Canada. 2005. Census of Canada. Statistics Canada, Ottawa, Ontario, Canada. http://www12.statcan.ca/english/census01/home/index.cfm.
45. Steele, L. S., D. W. MacPherson, J. Kim, J. S. Keystone, and B. D. Gushulak. 2007. The sero-prevalence of antibodies to Trypanosoma cruzi in Latin American refugees and immigrants to Canada. J. Immigr. Minor. Health 9: 43-47.
46. Steinberg, D., and P. Colla. 1995 CART: tree-structured non-parametric data analysis. Salford Systems, San Diego, CA.
47. Umekita, L. F., S. M. Carneiro, A. Sesso, and I. Mota. 1999. One fate of bloodstream trypomastigote forms of Trypanosoma cruzi after immune clearance: an ultrastructural study. J. Parasitol. 85: 867-872.
48. U.S. Census Bureau. 2005. QuickFacts. U.S. Census Bureau, Washington, DC. http://quickfacte.census.gov/qfd/states/00000.html.
49. Wendel, S., and A. L. Gonzaga. 1993. Chagas' disease and blood transfusion: a New World problem? Vox Sang. 64: 1-12.
50. Whelan, L. C, K. A. Power, D. T. McDowell, J. Kennedy, and W. M. Gallagher. 2008. Applications of SELDI-MS technology in oncology. J. Cell. Mol. Med. 12: 1535-1547.
51. WHO. 2000. Certification of interruption of transmission. Wkly. Epidemiol. Rec. 75: 10-12.
52. Wincker, P., M. F. Bosseno, C. Britto, N. Yaksic, M. A. Cardoso, C. M. Morel, and S. F. Breniere. 1994. High correlation between Chagas' disease serology and PCR-based detection of Trypanosoma cruzi kmetoplast DNA in Bolivian, children living in an endemic area. FEMS Microbiol. Lett. 124: 419-423.
53. Xiao, Z., D. Prieto, T. P. Conrads, T. D. Veenstra, and H. J. Issaq. 2005. Proteomic patterns: their potential for disease diagnosis. Mol. Cell. Endocrinol. 230: 95-106.
54. Yip, T. T. C., J. W. M. Chan, W. C. S. Cho, T. T. Yip, Z. Wang, T. L. Kwan, S. C. K. Law, D. N. C. Tsang, J. K. C. Chan, K. C. Lee, W. W. Cheng, V. W. S. Ma, C. Yip, C. K. P. Lim, R. K. C. Ngan, J. S. K. Au, A. Chan, W. W. L. Lim, and Queen Elizabeth Hospital/Hong Kong Government Virus Unit/Ciphergen SARS Proteomics Study Group. 2005. Protein chip array profiling analysis in patients with severe acute respiratory syndrome identified serum amyloid A protein as a biomarker potentially useful in monitoring the extent of pneumonia. Clin. Chem. 51: 47-55.