Early detection of head and neck cancer: Development of a novel screening tool using multiplexed immunobead-based biomarker profiling

Cancer Epidemiology Biomarkers and Prevention

Volumn 16, Issue 1, 2007, Pages 102-107

  Linkov, Faina ^a   Lisovich, Alex ^b   Yurkovetsky, Zoya ^a   Marrangoni, Adele ^a   Velikokhatnaya, Lyudmila ^a   Nolen, Brian ^a   Winans, Matthew ^a   Bigbee, William ^a   Siegfried, Jill ^a,c   Lokshin, Anna ^a   Ferris, Robert L ^a,b,c  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN; ALPHA INTERFERON; BIOLOGICAL MARKER; CA 125 ANTIGEN; CHEMOKINE; CYTOKERATIN 19; CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GELATINASE A; GRANULOCYTE COLONY STIMULATING FACTOR; GROWTH FACTOR; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 17; INTERLEUKIN 1ALPHA RECEPTOR; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 7; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESOTHELIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; RANTES; SOMATOMEDIN BINDING PROTEIN; STROMELYSIN; TUMOR ANTIGEN; TUMOR MARKER; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER SCREENING; CONTROLLED STUDY; ENZYME IMMUNOASSAY; FEMALE; HEAD AND NECK CANCER; HUMAN; IMMUNOASSAY; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; T LYMPHOCYTE;

ADULT; AGED; AGED, 80 AND OVER; CA-125 ANTIGEN; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; CHEMOKINES; CYTOKINES; EARLY DIAGNOSIS; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; IMMUNOASSAY; MALE; MASS SCREENING; MICROSPHERES; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; SMOKING; TUMOR MARKERS, BIOLOGICAL;

EID: 33846636976     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-06-0602     Document Type: Article

References (25)

1. American Cancer Society. Cancer facts and figures-1997. Washington (DC): American Cancer Society; 1997.
2. Ferris RL, Martinez I, Sirianni N, et al. Human papillomavirus-16 associated squamous cell carcinoma of the head and neck (SCCHN): a natural disease model provides insights into viral carcinogenesis. Eur J Cancer 2005;41: 807-15.
3. Gillison ML, Koch WM, Capone RB, et al. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst 2000;92:709-20.
4. Thekdi AA, Ferris RL. Diagnostic assessment of laryngeal cancer. Otolaryngol Clin North Am 2002;35:953-69, v.
5. Vikram B, Strong EW, Shah JP, Spiro R. Second malignant neoplasms in patients successfully treated with multimodality treatment for advanced head and neck cancer. Head Neck Surg 1984;6:734-7.
6. Druzgal CHCZ, Yeh NT, Thomas GR, et al. A pilot study of longitudinal serum cytokine and angiogenesis factor levels as markers of therapeutic response and survival in patients with head and neck squamous cell carcinoma. Head Neck 2005.
7. Gokhale AS, Haddad RI, Cavacini LA, et al. Serum concentrations of interleukin-8, vascular endothelial growth factor, and epidermal growth factor receptor in patients with squamous cell cancer of the head and neck. Oral Oncol 2005;41:70-6.
8. Hathaway B, Landsittel DP, Gooding W, et al. Multiplexed analysis of serum cytokines as biomarkers in squamous cell carcinoma of the head and neck patients. Laryngoscope 2005;115:522-7.
9. Lathers DM, Achille NJ, Young MR. Incomplete Th2 skewing of cytokines in plasma of patients with squamous cell carcinoma of the head and neck. Hum Immunol 2003;64:1160-6.
10. Lathers DM, Young MR. Increased aberrance of cytokine expression in plasma of patients with more advanced squamous cell carcinoma of the head and neck. Cytokine 2004;25:220-8.
11. Pries R, Wollenberg B. Cytokines in head and neck cancer. Cytokine Growth Factor Rev 2006;17:141-6.
12. Vignali DA. Multiplexed particle-based flow cytometric assays. J Immunol Methods 2000;243:243-55.
13. Wang J, Xi L, Hunt JL, et al. Expression pattern of chemokine receptor 6 (CCR6) and CCR7 in squamous cell carcinoma of the head and neck identifies a novel metastatic phenotype. Cancer Res 2004;64:1861-6.
14. Wang J, Zhang X, Thomas SM, et al. Chemokine receptor 7 activates phosphoinositide-3 kinase-mediated invasive and prosurvival pathways in head and neck cancer cells independent of EGFR. Oncogene 2005.
15. Zinzindohoue FBH, Hans S, Loriot MA, et al. Single nucleotide polymorphisms in MMP1 and MMP3 gene promoters as risk factor in head and neck squamous cell carcinoma. Anticancer Resh 2004;24:2021-6.
16. Weber RS, Pathak S, Frankenthaler R, Gallick GE, Sacks PG. Effect of epidermal growth factor (EGF) on a newly established head and neck squamous carcinoma cell line. Otolaryngol Head Neck Surg 1988;99:567-73.
17. Grandis JR, Tweardy DJ. Elevated levels of transforming growth factor α and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer. Cancer Res 1993;53:3579-84.
18. Ruokolainen H, Paakko P, Turpeenniemi-Hujanen T. Tissue and circulating immunoreactive protein for MMP-2 and TIMP-2 in head and neck squamous cell carcinoma-tissue immunoreactivity predicts aggressive clinical course. Mod Pathol 2006;19:208-17.
19. Wolf JSZ, Chen G, Dong JB, et al. IL-1α promotes nuclear factor-κB and AP-1 induced IL-8 expression, cell survival and proliferation in head and neck squamous cell carcinoma. Clin Cancer Res 2001;7:1812-20.
20. Bancroft CC, Chen Z, Dong G, et al. Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-κB signal pathways. Clin Cancer Res 2001;7:435-42.
21. Chen Z, Colon I, Ortiz N, et al. Effects of interleukin-1α, interleukin-1 receptor antagonist, and neutralizing antibody on proinflammatory cytokine expression by human squamous cell carcinoma lines. Cancer Res 1998;58: 3668-76.
22. Dong G, Chen Z, Li ZY, Yeh NT, Bancroft CC, Van Waes C. Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3K signal pathways contributes to expression of proangiogenic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma. Cancer Res 2001;61:5911-8.
23. Dong G, Loukinova E, Smith CW, Chen Z, Van Waes C. Genes differentially expressed with malignant transformation and metastatic tumor progression of murine squamous cell carcinoma. J Cell Biochem 1997;28-29 Suppl:90-100.
24. Ondrey FG, Dong G, Sunwoo J, et al. Constitutive activation of transcription factors NF-κB, AP-1, and NF-IL6 in human head and neck squamous cell carcinoma cell lines that express pro-inflammatory and pro-angiogenic cytokines. Mol Carcinog 1999;26:119-29.
25. Walston J, Xue Q, Semba RD, et al. Serum antioxidants, inflammation, and total mortality in older women. Am J Epidemiol 2006;163:18-26.