메뉴 건너뛰기




Volumn , Issue , 2008, Pages 75-110

Cell metabolism and its control in culture

Author keywords

[No Author keywords available]

Indexed keywords


EID: 77950461851     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (2)

References (116)
  • 1
    • 0025954883 scopus 로고
    • Compartmentation of folate-mediated one-carbon metabolism in eukaryotes
    • Appling DR (1991), Compartmentation of folate-mediated one-carbon metabolism in eukaryotes, FASEB J. 5:2645-2651.
    • (1991) FASEB J. , vol.5 , pp. 2645-2651
    • Appling, D.R.1
  • 2
    • 0019744035 scopus 로고
    • Uptake of amino acid and glucose by BHK-21 clone 13 suspension cells during cell growth
    • Arathoon WR, Telling CR (1982), Uptake of amino acid and glucose by BHK-21 clone 13 suspension cells during cell growth, Dev. Biol. Stand. 50:145-154.
    • (1982) Dev. Biol. Stand. , vol.50 , pp. 145-154
    • Arathoon, W.R.1    Telling, C.R.2
  • 3
    • 0015784842 scopus 로고
    • Essential fatty acid requirements of cells in tissue culture: a review
    • Bailey JM, Dunbar LM (1973), Essential fatty acid requirements of cells in tissue culture: a review, Exp. Mol. Pathol. 18:142-161.
    • (1973) Exp. Mol. Pathol. , vol.18 , pp. 142-161
    • Bailey, J.M.1    Dunbar, L.M.2
  • 4
    • 0023224254 scopus 로고
    • Linoleate metabolites enhance the in vitro proliferative response of mouse mammary epithelial cells to epidermal growth factor
    • Bandyopadhyay GK, Imagawa W, Wallace D, Nandi S (1987), Linoleate metabolites enhance the in vitro proliferative response of mouse mammary epithelial cells to epidermal growth factor, J. Biol. Chem. 262:2750-2756.
    • (1987) J. Biol. Chem. , vol.262 , pp. 2750-2756
    • Bandyopadhyay, G.K.1    Imagawa, W.2    Wallace, D.3    Nandi, S.4
  • 5
    • 0024210681 scopus 로고
    • A novel function of glutamine in cell culture: utilization of glutamine for the uptake of cystine in human fibroblasts
    • Bannai S, Ishii T (1988), A novel function of glutamine in cell culture: utilization of glutamine for the uptake of cystine in human fibroblasts, J. Cell. Physiol. 137:360-366.
    • (1988) J. Cell. Physiol. , vol.137 , pp. 360-366
    • Bannai, S.1    Ishii, T.2
  • 6
    • 14744283551 scopus 로고
    • High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selectable marker
    • Bebbington CR, Renner G, Thomson S, King D, Abrams D, Yarranton GT (1992), High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selectable marker, Biotechnology 10:169-175.
    • (1992) Biotechnology , vol.10 , pp. 169-175
    • Bebbington, C.R.1    Renner, G.2    Thomson, S.3    King, D.4    Abrams, D.5    Yarranton, G.T.6
  • 9
    • 85080583363 scopus 로고
    • The serine and glycine requirements of cultured human lymphocyte lines
    • Acton RT, Lynn JD (Eds), Academic Press, New York
    • Birch JR, Hopkins DW (1977), The serine and glycine requirements of cultured human lymphocyte lines. In: Acton RT, Lynn JD (Eds), Cell Culture and its Applications, Academic Press, New York, pp. 503-511.
    • (1977) Cell Culture and its Applications , pp. 503-511
    • Birch, J.R.1    Hopkins, D.W.2
  • 13
    • 0028710051 scopus 로고    scopus 로고
    • Adaptation of mammalian cells to non-ammoniagenic media
    • Butler M, Christie A (2004), Adaptation of mammalian cells to non-ammoniagenic media, Cytotechnology 15:87-94.
    • (2004) Cytotechnology , vol.15 , pp. 87-94
    • Butler, M.1    Christie, A.2
  • 14
    • 0028969986 scopus 로고
    • The effects of fatty acids on hybridoma cell growth and antibody productivity in serum-free cultures
    • Butler M, Huzel N (1995), The effects of fatty acids on hybridoma cell growth and antibody productivity in serum-free cultures, J. Biotechnol. 39:165-173.
    • (1995) J. Biotechnol. , vol.39 , pp. 165-173
    • Butler, M.1    Huzel, N.2
  • 15
    • 0001464709 scopus 로고
    • The effects of glutamine utilization and ammonia production on the growth of BHK cells in microcarrier cultures
    • Butler M, Spier RE (1984), The effects of glutamine utilization and ammonia production on the growth of BHK cells in microcarrier cultures, J. Biotechnol. 1:187-196.
    • (1984) J. Biotechnol. , vol.1 , pp. 187-196
    • Butler, M.1    Spier, R.E.2
  • 16
    • 0020105588 scopus 로고
    • MDCK microcarrier cultures: seeding density effects and amino acid utilization
    • Butler M, Thilly WG (1982), MDCK microcarrier cultures: seeding density effects and amino acid utilization, In Vitro 18:213-219.
    • (1982) In Vitro , vol.18 , pp. 213-219
    • Butler, M.1    Thilly, W.G.2
  • 17
    • 0020645556 scopus 로고
    • High yields from microcarrier cultures by medium perfusion
    • Butler M, Imamura T, Thomas WG, Thilly M (1983), High yields from microcarrier cultures by medium perfusion, J. Cell. Sci. 61:351-363.
    • (1983) J. Cell. Sci. , vol.61 , pp. 351-363
    • Butler, M.1    Imamura, T.2    Thomas, W.G.3    Thilly, M.4
  • 18
    • 0031052949 scopus 로고    scopus 로고
    • Unsaturated fatty acids enhance cell yields and perturb the energy metabolism of an antibody-secreting hybridoma
    • Butler M, Huzel N, Barnabé N (1997), Unsaturated fatty acids enhance cell yields and perturb the energy metabolism of an antibody-secreting hybridoma, Biochem. J. 322:615-623.
    • (1997) Biochem. J. , vol.322 , pp. 615-623
    • Butler, M.1    Huzel, N.2    Barnabé, N.3
  • 19
    • 0032922838 scopus 로고    scopus 로고
    • Linoleic acid improves the robustness of cells in agitated cultures
    • Butler M, Huzel N, Barnabé N, Gray T, Bajno L (1999), Linoleic acid improves the robustness of cells in agitated cultures, Cytotechnology 30:27-36.
    • (1999) Cytotechnology , vol.30 , pp. 27-36
    • Butler, M.1    Huzel, N.2    Barnabé, N.3    Gray, T.4    Bajno, L.5
  • 20
    • 0024764155 scopus 로고
    • Nutritional aspects of growth of animal cells in culture
    • Butler, M. and Jenkins, H. (1989), Nutritional aspects of growth of animal cells in culture. J. Biotechnol. 12, 97-110.
    • (1989) J. Biotechnol. , vol.12 , pp. 97-110
    • Butler, M.1    Jenkins, H.2
  • 21
    • 0025963076 scopus 로고
    • Effect of fatty acids on the proliferation of concanavalin A-stimulated rat lymph node lymphocytes
    • Calder PC, Bond JA, Bevan SJ, Hunt SV, Newsholme EA (1991), Effect of fatty acids on the proliferation of concanavalin A-stimulated rat lymph node lymphocytes, Int. J. Biochem. 23:579-588.
    • (1991) Int. J. Biochem. , vol.23 , pp. 579-588
    • Calder, P.C.1    Bond, J.A.2    Bevan, S.J.3    Hunt, S.V.4    Newsholme, E.A.5
  • 22
    • 0028200972 scopus 로고
    • Incorporation of fatty acids by concanavalin A-stimulated lymphocytes and the effects on fatty acid composition and membrane fluidity
    • Calder PC, Yaqoob P, Harvey DJ, Watts A, Newsholme EA (1994), Incorporation of fatty acids by concanavalin A-stimulated lymphocytes and the effects on fatty acid composition and membrane fluidity, Biochem. J. 300:509-518.
    • (1994) Biochem. J. , vol.300 , pp. 509-518
    • Calder, P.C.1    Yaqoob, P.2    Harvey, D.J.3    Watts, A.4    Newsholme, E.A.5
  • 23
    • 0025036574 scopus 로고
    • Facilitated diffusion of glucose
    • Carruthers A (1990), Facilitated diffusion of glucose, Physiol. Rev. 70:1135-1176.
    • (1990) Physiol. Rev. , vol.70 , pp. 1135-1176
    • Carruthers, A.1
  • 25
    • 17744394562 scopus 로고    scopus 로고
    • Growth and metabolism of marine fish Chinook salmon embryo cells: response to lack of glucose and glutamine
    • Chen J, Sun X, Zhang Y (2005), Growth and metabolism of marine fish Chinook salmon embryo cells: response to lack of glucose and glutamine, Biotechnol. Lett. 27:395-401.
    • (2005) Biotechnol. Lett. , vol.27 , pp. 395-401
    • Chen, J.1    Sun, X.2    Zhang, Y.3
  • 26
    • 18144373127 scopus 로고    scopus 로고
    • Effects of amino acids additions on ammonium stressed CHO cells
    • Chen P, Harcum SW (2005), Effects of amino acids additions on ammonium stressed CHO cells, J. Biotechnol. 117:277-286.
    • (2005) J. Biotechnol. , vol.117 , pp. 277-286
    • Chen, P.1    Harcum, S.W.2
  • 27
    • 0027942360 scopus 로고
    • Glutamine-based dipeptides are utilized in mammalian cell culture by extracellular hydrolysis catalyzed by a specific peptidase
    • Christie A, Butler M (1994), Glutamine-based dipeptides are utilized in mammalian cell culture by extracellular hydrolysis catalyzed by a specific peptidase, J. Biotechnol. 37:277-290.
    • (1994) J. Biotechnol. , vol.37 , pp. 277-290
    • Christie, A.1    Butler, M.2
  • 28
    • 0003696940 scopus 로고
    • Fatty acid paradoxes in the control of cell proliferation:prostaglandins, lipid peroxides and cooxidation reactions
    • Pryor WA (Ed.), Academic Press, New York
    • Cornwell DG, Morisaki N (1984), Fatty acid paradoxes in the control of cell proliferation:prostaglandins, lipid peroxides and cooxidation reactions, In: Pryor WA (Ed.), Free Radicals in Biology VI, Academic Press, New York, pp. 95-147.
    • (1984) Free Radicals in Biology VI , pp. 95-147
    • Cornwell, D.G.1    Morisaki, N.2
  • 29
    • 0002371029 scopus 로고
    • A systematic approach to describing and analyzing metabolic control systems
    • Crabtree B, Newsholme EA (1987), A systematic approach to describing and analyzing metabolic control systems, Trends Biochem. Sci. 12:6-12.
    • (1987) Trends Biochem. Sci. , vol.12 , pp. 6-12
    • Crabtree, B.1    Newsholme, E.A.2
  • 30
    • 0018672517 scopus 로고
    • Kinetics of 3-O-methyl-D-glucose transport in isolated rat hepatocytes
    • Craik JD, Elliot KRF (1979), Kinetics of 3-O-methyl-D-glucose transport in isolated rat hepatocytes, Biochem. J. 182:503-508.
    • (1979) Biochem. J. , vol.182 , pp. 503-508
    • Craik, J.D.1    Elliot, K.R.F.2
  • 32
    • 0017087846 scopus 로고
    • Energy metabolism in respiration deficient and wild type Chinese hamster fibroblasts in culture
    • Donelly M, Scheffler IE (1976), Energy metabolism in respiration deficient and wild type Chinese hamster fibroblasts in culture, J. Cell. Physiol. 18:39-52.
    • (1976) J. Cell. Physiol. , vol.18 , pp. 39-52
    • Donelly, M.1    Scheffler, I.E.2
  • 35
    • 0026219281 scopus 로고
    • Factors controlling cell proliferation and antibody production in mouse hybridoma cells: I. Influence of the amino acid supply
    • Duval D, Demangel C, Munier-Jolain K, Miossec S, Geahel I (1991), Factors controlling cell proliferation and antibody production in mouse hybridoma cells: I. Influence of the amino acid supply, Biotechnol. Bioeng. 38:561-570.
    • (1991) Biotechnol. Bioeng. , vol.38 , pp. 561-570
    • Duval, D.1    Demangel, C.2    Munier-Jolain, K.3    Miossec, S.4    Geahel, I.5
  • 36
    • 0026487376 scopus 로고
    • Role of metabolic waste products in the control of cell proliferation and antibody production by mouse hybridoma cells
    • Duval D, Demangel C, Miossec S, Geahel I (1992), Role of metabolic waste products in the control of cell proliferation and antibody production by mouse hybridoma cells, Hybridoma 11:311-322.
    • (1992) Hybridoma , vol.11 , pp. 311-322
    • Duval, D.1    Demangel, C.2    Miossec, S.3    Geahel, I.4
  • 37
    • 0001572284 scopus 로고
    • Nutrition needs of mammalian cells in tissue cultures
    • Eagle H (1955), Nutrition needs of mammalian cells in tissue cultures, Science 122:501-504.
    • (1955) Science , vol.122 , pp. 501-504
    • Eagle, H.1
  • 38
    • 0001398727 scopus 로고
    • Amino acid metabolism in mammalian cell cultures
    • Eagle H (1959), Amino acid metabolism in mammalian cell cultures, Science 130:432-437.
    • (1959) Science , vol.130 , pp. 432-437
    • Eagle, H.1
  • 39
    • 0345378505 scopus 로고
    • The population dependent requirement by cultured mammalian cells for metabolites which they can synthesize
    • Eagle H, Piez K (1962), The population dependent requirement by cultured mammalian cells for metabolites which they can synthesize, J. Exp. Med. 116:29-43.
    • (1962) J. Exp. Med. , vol.116 , pp. 29-43
    • Eagle, H.1    Piez, K.2
  • 41
    • 0027909873 scopus 로고
    • Utilization of glucose and amino acids in insect cell cultures: quantifying the metabolic flows within the primary pathways and medium development
    • Ferrance JP, Goel A, Ataai MM (1993), Utilization of glucose and amino acids in insect cell cultures: quantifying the metabolic flows within the primary pathways and medium development, Biotechnol. Bioeng. 42:697-707.
    • (1993) Biotechnol. Bioeng. , vol.42 , pp. 697-707
    • Ferrance, J.P.1    Goel, A.2    Ataai, M.M.3
  • 42
    • 0027692808 scopus 로고
    • Glucose and glutamine metabolism of a murine B-lymphocyte grown in batch culture
    • Fitzpatrick L, Jenkins HA, Butler M (1993), Glucose and glutamine metabolism of a murine B-lymphocyte grown in batch culture, Appl. Biochem. Biotechnol. 43:93-116.
    • (1993) Appl. Biochem. Biotechnol. , vol.43 , pp. 93-116
    • Fitzpatrick, L.1    Jenkins, H.A.2    Butler, M.3
  • 43
    • 0032485239 scopus 로고    scopus 로고
    • Ammonium ion and glucosamine dependent increases of oligosaccharide complexity in recombinant glycoproteins secreted from cultivated BHK-21 cells
    • Gawlitzek M, Valley U, Wagner R (1998), Ammonium ion and glucosamine dependent increases of oligosaccharide complexity in recombinant glycoproteins secreted from cultivated BHK-21 cells, Biotechnol. Bioeng. 57:518-528.
    • (1998) Biotechnol. Bioeng. , vol.57 , pp. 518-528
    • Gawlitzek, M.1    Valley, U.2    Wagner, R.3
  • 44
    • 0032587555 scopus 로고    scopus 로고
    • Incorporation of 15N from ammonium into the N-linked oligosaccharides of an immunoadhesin glycoprotein expressed in Chinese Hamster Ovary cells
    • Gawlitzek M, Papac DI, Sliwkowski MB, Ryll T (1999), Incorporation of 15N from ammonium into the N-linked oligosaccharides of an immunoadhesin glycoprotein expressed in Chinese Hamster Ovary cells, Glycobiology 9:125-131.
    • (1999) Glycobiology , vol.9 , pp. 125-131
    • Gawlitzek, M.1    Papac, D.I.2    Sliwkowski, M.B.3    Ryll, T.4
  • 45
    • 0034691229 scopus 로고    scopus 로고
    • Ammonium alters N-glycan structures of recombinant TNFR-IgG: degradative versus biosynthetic mechanisms
    • Gawlitzek M, Valley U, Wagner R (2000), Ammonium alters N-glycan structures of recombinant TNFR-IgG: degradative versus biosynthetic mechanisms. Biotechnol. Bioeng. 68:637-646.
    • (2000) Biotechnol. Bioeng. , vol.68 , pp. 637-646
    • Gawlitzek, M.1    Valley, U.2    Wagner, R.3
  • 46
    • 13544268489 scopus 로고    scopus 로고
    • Substitution of glutamine by pyruvate to reduce ammonia formation and growth inhibition of mammalian cells
    • Genzel Y, Ritter JB, Konig S, Alt R, Reichl U (2005) Substitution of glutamine by pyruvate to reduce ammonia formation and growth inhibition of mammalian cells. Biotechnol. Prog. 21:58-69.
    • (2005) Biotechnol. Prog. , vol.21 , pp. 58-69
    • Genzel, Y.1    Ritter, J.B.2    Konig, S.3    Alt, R.4    Reichl, U.5
  • 47
    • 0023763120 scopus 로고
    • Catabolic control of mammalian cell culture
    • Glacken MW (1988), Catabolic control of mammalian cell culture, Biotechnology 6:1941-1950.
    • (1988) Biotechnology , vol.6 , pp. 1941-1950
    • Glacken, M.W.1
  • 48
    • 85080592038 scopus 로고
    • Mathematical descriptions of hybridoma culture kinetics I. Initial metabolic rates
    • Glacken MW, Adema E, Sinskey AJ (1988), Mathematical descriptions of hybridoma culture kinetics I. Initial metabolic rates, Biotechnol. Bioeng. 28:1376-1389.
    • (1988) Biotechnol. Bioeng. , vol.28 , pp. 1376-1389
    • Glacken, M.W.1    Adema, E.2    Sinskey, A.J.3
  • 49
    • 0025886960 scopus 로고
    • Expression of human glucose transporters in Xenopus oocytes. Kinetic characterization and substrate specificities of the erythrocyte, liver, and brain isoforms
    • Gould GW, Thomas HM, Jess TJ, Bell GI (1991), Expression of human glucose transporters in Xenopus oocytes. Kinetic characterization and substrate specificities of the erythrocyte, liver, and brain isoforms, Biochemistry 30:5139-5145.
    • (1991) Biochemistry , vol.30 , pp. 5139-5145
    • Gould, G.W.1    Thomas, H.M.2    Jess, T.J.3    Bell, G.I.4
  • 51
    • 0032078486 scopus 로고    scopus 로고
    • Intracellular UDPN- acetylhexosamine pool affects N-glycan complexity: a mechanism of ammonium action on protein glycosylation
    • Gramatikos SI, Valley U, Nimtz M, Conrad HS, Wagner R (1998), Intracellular UDPN- acetylhexosamine pool affects N-glycan complexity: a mechanism of ammonium action on protein glycosylation, Biotechnol. Prog. 14:410-419.
    • (1998) Biotechnol. Prog. , vol.14 , pp. 410-419
    • Gramatikos, S.I.1    Valley, U.2    Nimtz, M.3    Conrad, H.S.4    Wagner, R.5
  • 52
    • 0004320666 scopus 로고    scopus 로고
    • Scaling-up of animal cell cultures
    • John RW (Ed.), 3rd Ed., Masters, Oxford University Press
    • Griffiths B (2000), Scaling-up of animal cell cultures, In: John RW (Ed.), Animal Cell Culture, 3rd Ed., Masters, Oxford University Press, pp. 19-63.
    • (2000) Animal Cell Culture , pp. 19-63
    • Griffiths, B.1
  • 53
    • 0014980833 scopus 로고
    • The effect of medium changes on the growth and metabolism of the human diploid cell
    • Griffiths JB (1971), The effect of medium changes on the growth and metabolism of the human diploid cell, WI-38, J. Cell Sci. 8:43-52.
    • (1971) WI-38, J. Cell Sci. , vol.8 , pp. 43-52
    • Griffiths, J.B.1
  • 54
    • 0027515728 scopus 로고
    • The role of short chain fatty acid substrates in aerobic and glycolytic metabolism in primary cultures of renal proximal tubule cells
    • Griner RD, Aleo MD, Schnellmann RG (1993), The role of short chain fatty acid substrates in aerobic and glycolytic metabolism in primary cultures of renal proximal tubule cells, In Vitro Cell Dev. Biol. Anim. 29A:649-655.
    • (1993) Vitro Cell Dev. Biol. Anim. , vol.29 , pp. 649-655
    • Griner, R.D.1    Aleo, M.D.2    Schnellmann, R.G.3
  • 55
    • 0032859002 scopus 로고    scopus 로고
    • Impact of culture conditions, culture media volumes and glucose content on metabolic properties of renal epithelial cell cultures. Are renal cells in tissue culture hypoxic?
    • Gstraunthaler G, Seppi T, Pfaller W (1999), Impact of culture conditions, culture media volumes and glucose content on metabolic properties of renal epithelial cell cultures. Are renal cells in tissue culture hypoxic?, Cell. Physiol. Biochem. 9:150-172.
    • (1999) Cell. Physiol. Biochem. , vol.9 , pp. 150-172
    • Gstraunthaler, G.1    Seppi, T.2    Pfaller, W.3
  • 56
    • 2442612236 scopus 로고    scopus 로고
    • Animal cell metabolism
    • Spier R (Ed.), Wiley & Sons, New York
    • Haggstrom L (2000), Animal cell metabolism In: Spier R (Ed.), Encyclopedia of Cell Technology, Wiley & Sons, New York, pp. 392-411.
    • (2000) Encyclopedia of Cell Technology , pp. 392-411
    • Haggstrom, L.1
  • 57
    • 0025340874 scopus 로고
    • Adaptation to non-ammoniagenic media and selective substrate feeding lead to enhanced yields in animal cell culture
    • Hassell T, Butler M (1990), Adaptation to non-ammoniagenic media and selective substrate feeding lead to enhanced yields in animal cell culture, J. Cell Sci. 96:501-508.
    • (1990) J. Cell Sci. , vol.96 , pp. 501-508
    • Hassell, T.1    Butler, M.2
  • 58
    • 0026196692 scopus 로고
    • Growth inhibition in animal cell culture: the effect of lactate and ammonia
    • Hassell T, Gleave S, Butler M (1991), Growth inhibition in animal cell culture: the effect of lactate and ammonia, Appl. Biochem. Biotechnol. 30:29-41.
    • (1991) Appl. Biochem. Biotechnol. , vol.30 , pp. 29-41
    • Hassell, T.1    Gleave, S.2    Butler, M.3
  • 59
    • 0001181030 scopus 로고
    • Serum-free growth medium for the cultivation of a wide spectrum of mammalian cells in stirred bioreactors
    • Jager V, Lehmann J, Friedl P (1988), Serum-free growth medium for the cultivation of a wide spectrum of mammalian cells in stirred bioreactors, Cytotechnology 1:319-329.
    • (1988) Cytotechnology , vol.1 , pp. 319-329
    • Jager, V.1    Lehmann, J.2    Friedl, P.3
  • 60
    • 1842297541 scopus 로고    scopus 로고
    • The effect of dissolved oxygen on the metabolic profile of a murine hybridoma grown in serum-free medium in continuous culture
    • Jan DCH, Petch DA, Huzel N, Butler M (2000), The effect of dissolved oxygen on the metabolic profile of a murine hybridoma grown in serum-free medium in continuous culture, Biotechnol. Bioeng. 54:153-164.
    • (2000) Biotechnol. Bioeng. , vol.54 , pp. 153-164
    • Jan, D.C.H.1    Petch, D.A.2    Huzel, N.3    Butler, M.4
  • 61
    • 0026624835 scopus 로고
    • Facilitative glucose transporters. Regulatory mechanisms and deregulation in diabetes
    • Kahn BB (1992), Facilitative glucose transporters. Regulatory mechanisms and deregulation in diabetes, J. Clin. Invest. 89:1367-1374.
    • (1992) J. Clin. Invest. , vol.89 , pp. 1367-1374
    • Kahn, B.B.1
  • 62
    • 0027970152 scopus 로고
    • Cytokine production and DNA synthesis in human peripheral lymphocytes in response to palmitic, stearic, oleic and linoleic acids
    • Karsten S, Schafer G, Schauder P (1994), Cytokine production and DNA synthesis in human peripheral lymphocytes in response to palmitic, stearic, oleic and linoleic acids, J. Cell Physiol. 161:15-22.
    • (1994) J. Cell Physiol. , vol.161 , pp. 15-22
    • Karsten, S.1    Schafer, G.2    Schauder, P.3
  • 63
    • 0023812475 scopus 로고
    • Evidence for a family of human glucose transporter-like proteins. Sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues
    • Kayano T, Fukumoto H, Eddy RL, Fan YS, Byers MG, Shows TB, Bell GI (1988), Evidence for a family of human glucose transporter-like proteins. Sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues, J. Biol. Chem. 263:15245-15248.
    • (1988) J. Biol. Chem. , vol.263 , pp. 15245-15248
    • Kayano, T.1    Fukumoto, H.2    Eddy, R.L.3    Fan, Y.S.4    Byers, M.G.5    Shows, T.B.6    Bell, G.I.7
  • 64
    • 0028231367 scopus 로고
    • Effect of acid lactic on the kinetics of growth and antibody production in a murine hybridoma: secretion patterns during the cell cycle
    • Kromenaker SJ, Srienc F (1994), Effect of acid lactic on the kinetics of growth and antibody production in a murine hybridoma: secretion patterns during the cell cycle, J. Biotechnol. 34:13-34.
    • (1994) J. Biotechnol. , vol.34 , pp. 13-34
    • Kromenaker, S.J.1    Srienc, F.2
  • 65
    • 0016659515 scopus 로고
    • The quantitative requirements of human diploid cells (strain MRC-5) for amino acids, vitamins and serum
    • Lambert J, Pirt SJ (1975), The quantitative requirements of human diploid cells (strain MRC-5) for amino acids, vitamins and serum, J. Cell Sci. 17:397-41.
    • (1975) J. Cell Sci. , vol.17 , pp. 341-397
    • Lambert, J.1    Pirt, S.J.2
  • 66
    • 0023880944 scopus 로고
    • End products of glucose and glutamine metabolism by cultured cell lines
    • Lanks KW, Li PW (1988), End products of glucose and glutamine metabolism by cultured cell lines, J. Cell Physiol. 135:151-155.
    • (1988) J. Cell Physiol. , vol.135 , pp. 151-155
    • Lanks, K.W.1    Li, P.W.2
  • 67
    • 0031239859 scopus 로고    scopus 로고
    • Effects of ammonium and lactate on growth and metabolism of a recombinant Chinese Hamster Ovary cell culture
    • Lao M, Toth D (1997), Effects of ammonium and lactate on growth and metabolism of a recombinant Chinese Hamster Ovary cell culture, Biotechnol. Prog. 13:688-691.
    • (1997) Biotechnol. Prog. , vol.13 , pp. 688-691
    • Lao, M.1    Toth, D.2
  • 68
    • 0026484670 scopus 로고
    • Glutamine limited fed-batch culture reduces the overflow metabolism of amino acids in myeloma cells
    • Ljunggren J, Häggström L (1992), Glutamine limited fed-batch culture reduces the overflow metabolism of amino acids in myeloma cells, Cytotechnology 8:45-56.
    • (1992) Cytotechnology , vol.8 , pp. 45-56
    • Ljunggren, J.1    Häggström, L.2
  • 69
    • 0029166683 scopus 로고
    • Specific growth rate as a parameter for tracing growth limiting substances in animal cell cultures
    • Ljunggren J, Häggström L (1995), Specific growth rate as a parameter for tracing growth limiting substances in animal cell cultures, J. Biotechnol. 42:163-175.
    • (1995) J. Biotechnol. , vol.42 , pp. 163-175
    • Ljunggren, J.1    Häggström, L.2
  • 71
    • 0027480269 scopus 로고
    • Uptake of glutamate, not glutamine synthetase, regulates adaptation of mammalian cells to glutamine-free medium
    • McDermott RH, Butler M (1993), Uptake of glutamate, not glutamine synthetase, regulates adaptation of mammalian cells to glutamine-free medium, J. Cell Sci. 104:51-58.
    • (1993) J. Cell Sci. , vol.104 , pp. 51-58
    • McDermott, R.H.1    Butler, M.2
  • 72
    • 0002643676 scopus 로고
    • Glutaminolysis in animal cells
    • Morgan MM (Ed.), Plenum, New York
    • McKeehan WL (1986), Glutaminolysis in animal cells, In: Morgan MM (Ed.), Carbohydrate Metabolism in Cultured Cells, Plenum, New York, pp. 111-150.
    • (1986) Carbohydrate Metabolism in Cultured Cells , pp. 111-150
    • McKeehan, W.L.1
  • 73
    • 0025410052 scopus 로고
    • Effect of ammonium ion and extracellular pH on hybridoma cell metabolism and antibody production
    • McQueen A, Bailey E (1990), Effect of ammonium ion and extracellular pH on hybridoma cell metabolism and antibody production, Biotechnol. Bioeng. 35:897-907.
    • (1990) Biotechnol. Bioeng. , vol.35 , pp. 897-907
    • McQueen, A.1    Bailey, E.2
  • 74
    • 33646549629 scopus 로고    scopus 로고
    • Metabolism of PER.C61 cells cultivated under fedbatch conditions at low glucose and glutamine levels
    • Maranga L, Goochee CF (2006), Metabolism of PER.C61 cells cultivated under fedbatch conditions at low glucose and glutamine levels, Biotechnol. Bioeng. 94:139-150.
    • (2006) Biotechnol. Bioeng. , vol.94 , pp. 139-150
    • Maranga, L.1    Goochee, C.F.2
  • 75
    • 0345556734 scopus 로고
    • Amino acid metabolism I: General Pathways
    • Devlin TM (Ed.), 2nd Ed. Wiley, New York
    • Mehler AH (1982), Amino acid metabolism I: General Pathways, In: Devlin TM (Ed.), Textbook of Biochemistry with Clinical Correlations, 2nd Ed. Wiley, New York, pp. 437-452.
    • (1982) Textbook of Biochemistry with Clinical Correlations , pp. 437-452
    • Mehler, A.H.1
  • 76
    • 0028961819 scopus 로고
    • Effects of glucose supply on myeloma growth and metabolism in chemostat culture
    • Meijer JJ, van Dijken JP (1995), Effects of glucose supply on myeloma growth and metabolism in chemostat culture, J. Cell. Physiol. 162:191-198.
    • (1995) J. Cell. Physiol. , vol.162 , pp. 191-198
    • Meijer, J.J.1    van Dijken, J.P.2
  • 77
    • 0345486508 scopus 로고
    • Transamination
    • Nord FF (Ed.), Interscience, New York
    • Meister A (1955), Transamination, In: Nord FF (Ed.), Advances in Enzymology, Interscience, New York, pp. 185-246.
    • (1955) Advances in Enzymology , pp. 185-246
    • Meister, A.1
  • 78
    • 34250092706 scopus 로고
    • Transient response of hybridoma cells to lactate and ammonia pulse and step changes in continuous culture
    • Miller WM, Wilke CR, Blanch HW (1988), Transient response of hybridoma cells to lactate and ammonia pulse and step changes in continuous culture, Bioprocess Eng. 3:113-122.
    • (1988) Bioprocess Eng. , vol.3 , pp. 113-122
    • Miller, W.M.1    Wilke, C.R.2    Blanch, H.W.3
  • 79
    • 84996094699 scopus 로고
    • Transient response of hybridoma cells to nutrient additions in continuous culture: I. Glucose pulse and step changes
    • Miller WM, Wilke CR, Blanch HW (1989), Transient response of hybridoma cells to nutrient additions in continuous culture: I. Glucose pulse and step changes, Biotechnol. Bioeng. 33:487-499.
    • (1989) Biotechnol. Bioeng. , vol.33 , pp. 487-499
    • Miller, W.M.1    Wilke, C.R.2    Blanch, H.W.3
  • 82
    • 0030049769 scopus 로고    scopus 로고
    • Comparative analysis of glucose and glutamine metabolism in transformed mammalian cell lines, insect and primary liver cells
    • Neerman J, Wagner R (1996), Comparative analysis of glucose and glutamine metabolism in transformed mammalian cell lines, insect and primary liver cells, J. Cell. Physiol. 166:152-169.
    • (1996) J. Cell. Physiol. , vol.166 , pp. 152-169
    • Neerman, J.1    Wagner, R.2
  • 85
    • 0025425146 scopus 로고
    • Hybridoma growth limitations: the roles of energy metabolism and ammonium production
    • Newland M, Greenfield PF, Reid S (1990), Hybridoma growth limitations: the roles of energy metabolism and ammonium production, Cytotechnology 3:215-229.
    • (1990) Cytotechnology , vol.3 , pp. 215-229
    • Newland, M.1    Greenfield, P.F.2    Reid, S.3
  • 87
    • 0025514467 scopus 로고
    • Effects of dissolved oxygen on hybridoma cell growth, metabolism and antibody production kinetics on continuous culture
    • Ozturk SS, Palssom BO (1990), Effects of dissolved oxygen on hybridoma cell growth, metabolism and antibody production kinetics on continuous culture, Biotechnol. Prog. 6:437-446.
    • (1990) Biotechnol. Prog. , vol.6 , pp. 437-446
    • Ozturk, S.S.1    Palssom, B.O.2
  • 88
    • 0032937141 scopus 로고    scopus 로고
    • Modification of glucose and glutamine metabolism in hybridoma cells through metabolic engineering
    • Paredes C, Prats E, Cairó JJ, Azorín F, Cornudella L, Gódia F (1999), Modification of glucose and glutamine metabolism in hybridoma cells through metabolic engineering, Cytotechnology 30:85-93.
    • (1999) Cytotechnology , vol.30 , pp. 85-93
    • Paredes, C.1    Prats, E.2    Cairó, J.J.3    Azorín, F.4    Cornudella, L.5    Gódia, F.6
  • 89
    • 0014028046 scopus 로고
    • Crystallization and properties of rabbit skeletal muscle phosphofructokinase
    • Parmeggiani A, Luft JH, Love DS, Krebs EG (1966), Crystallization and properties of rabbit skeletal muscle phosphofructokinase, J. Biol. Chem. 241:4625-4637.
    • (1966) J. Biol. Chem. , vol.241 , pp. 4625-4637
    • Parmeggiani, A.1    Luft, J.H.2    Love, D.S.3    Krebs, E.G.4
  • 90
    • 0026607990 scopus 로고
    • Mammalian facilitative glucose transporter family. Structure and molecular regulation
    • Pessin JE, Bell GI (1992), Mammalian facilitative glucose transporter family. Structure and molecular regulation, Annu. Rev. Physiol. 54:911-930.
    • (1992) Annu. Rev. Physiol. , vol.54 , pp. 911-930
    • Pessin, J.E.1    Bell, G.I.2
  • 91
    • 0028077867 scopus 로고
    • Profile of energy metabolism in a murine hybridoma:glucose and glutamine utilization
    • Petch D, Butler M (1994), Profile of energy metabolism in a murine hybridoma:glucose and glutamine utilization, J. Cell. Physiol. 161:71-76.
    • (1994) J. Cell. Physiol. , vol.161 , pp. 71-76
    • Petch, D.1    Butler, M.2
  • 92
    • 0022657328 scopus 로고
    • Comparison of cell propagation methods for their effect on monoclonal antibody yield on fermentors
    • Reuveny S, Velez D, Macmillan JD, Millar L (1986), Comparison of cell propagation methods for their effect on monoclonal antibody yield on fermentors, J. Immunol. Methods 86:61-69.
    • (1986) J. Immunol. Methods , vol.86 , pp. 61-69
    • Reuveny, S.1    Velez, D.2    Macmillan, J.D.3    Millar, L.4
  • 93
    • 0018171346 scopus 로고
    • Membrane modification of Chinese hamster ovary cells
    • Rintoul DA, Sklar LA, Simoni RD (1978), Membrane modification of Chinese hamster ovary cells, J. Biol. Chem. 253:7447-7452.
    • (1978) J. Biol. Chem. , vol.253 , pp. 7447-7452
    • Rintoul, D.A.1    Sklar, L.A.2    Simoni, R.D.3
  • 95
    • 0019277748 scopus 로고
    • The growth requirements of SV40 virus transformed Balb/c-3T3 cells in serum-free monolayer culture
    • Rockwell GA, Sato GH, McClure DB (1980), The growth requirements of SV40 virus transformed Balb/c-3T3 cells in serum-free monolayer culture, J. Cell. Physiol. 103:323-331.
    • (1980) J. Cell. Physiol. , vol.103 , pp. 323-331
    • Rockwell, G.A.1    Sato, G.H.2    McClure, D.B.3
  • 96
    • 13544255561 scopus 로고    scopus 로고
    • Enhanced production of monomeric interferon-_ by CHO cells through the control of culture conditions
    • Rodriguez J, Spearman M, Huzel N, Butler M (2005), Enhanced production of monomeric interferon-_ by CHO cells through the control of culture conditions. Biotechnol. Prog. 21:22-30.
    • (2005) Biotechnol. Prog. , vol.21 , pp. 22-30
    • Rodriguez, J.1    Spearman, M.2    Huzel, N.3    Butler, M.4
  • 97
    • 0025201334 scopus 로고
    • Effects of fatty acids and inhibitors of eicosanoid synthesis on the growth of a human breast cancer cell line in culture
    • Rose DP, Connolly JM (1990), Effects of fatty acids and inhibitors of eicosanoid synthesis on the growth of a human breast cancer cell line in culture, Cancer Res. 50:7139-7144.
    • (1990) Cancer Res. , vol.50 , pp. 7139-7144
    • Rose, D.P.1    Connolly, J.M.2
  • 98
    • 0023083465 scopus 로고
    • Fatty acid metabolism of isolated mammalian cells
    • Rosenthal MD (1987), Fatty acid metabolism of isolated mammalian cells, Prog. Lipid Res. 26:87-124.
    • (1987) Prog. Lipid Res. , vol.26 , pp. 87-124
    • Rosenthal, M.D.1
  • 99
    • 0022481177 scopus 로고
    • Influence of hypoxia and an acidic environment on the metabolism and viability of cultured cells: potential implications for cell death in tumors
    • Rotin D, Robinson B, Tannock IF (1986), Influence of hypoxia and an acidic environment on the metabolism and viability of cultured cells: potential implications for cell death in tumors, Cancer Res. 46:2821-2126.
    • (1986) Cancer Res. , vol.46 , pp. 2126-2821
    • Rotin, D.1    Robinson, B.2    Tannock, I.F.3
  • 100
    • 0028452886 scopus 로고
    • Biochemistry of growth inhibition by ammonium ions in mammalian cells
    • Ryll T, Valley U, Wagner R (1994), Biochemistry of growth inhibition by ammonium ions in mammalian cells, Biotechnol. Bioeng. 44:184-193.
    • (1994) Biotechnol. Bioeng. , vol.44 , pp. 184-193
    • Ryll, T.1    Valley, U.2    Wagner, R.3
  • 101
    • 0026020607 scopus 로고
    • Effect of free fatty acid and phospholipids on growth of and product formation by recombinant Baby Hamster Kidney (rBHK) and Chinese Hamster Ovary (rCHO) cells in culture
    • Schmid G, Zilg H, Eberhard U, Johannsen R (1991), Effect of free fatty acid and phospholipids on growth of and product formation by recombinant Baby Hamster Kidney (rBHK) and Chinese Hamster Ovary (rCHO) cells in culture, J. Biotechnol. 17:155-167.
    • (1991) J. Biotechnol. , vol.17 , pp. 155-167
    • Schmid, G.1    Zilg, H.2    Eberhard, U.3    Johannsen, R.4
  • 103
    • 0027190598 scopus 로고
    • A 1H/15N n.m.r. study of nitrogen metabolism in cultured mammalian cells
    • Street C, Delort AM, Braddock PSH, Brindle KM (1993), A 1H/15N n.m.r. study of nitrogen metabolism in cultured mammalian cells, Biochem. J. 291:485-492.
    • (1993) Biochem. J. , vol.291 , pp. 485-492
    • Street, C.1    Delort, A.M.2    Braddock, P.S.H.3    Brindle, K.M.4
  • 104
    • 0035525338 scopus 로고    scopus 로고
    • Effects of glucose on growth, metabolism and EPO expression in recombinant CHO cell cultures
    • Sun XM, Zhang YW (2001a), Effects of glucose on growth, metabolism and EPO expression in recombinant CHO cell cultures, Chin. J. Biotechnol. 17:698-702.
    • (2001) Chin. J. Biotechnol. , vol.17 , pp. 698-702
    • Sun, X.M.1    Zhang, Y.W.2
  • 105
    • 0035346850 scopus 로고    scopus 로고
    • Effects of ammonia on cell metabolism in the culture of recombinant CHO cells
    • Sun XM, Zhang YX (2001b), Effects of ammonia on cell metabolism in the culture of recombinant CHO cells, Chin. J. Biotechnol. 17:304-309.
    • (2001) Chin. J. Biotechnol. , vol.17 , pp. 304-309
    • Sun, X.M.1    Zhang, Y.X.2
  • 106
    • 0026668129 scopus 로고
    • The NADP-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase is not expressed in Spodoptera frugiperda cells
    • Tremblay GB, Mejia NR, MacKenzie RE (1992), The NADP-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase is not expressed in Spodoptera frugiperda cells, J. Biol. Chem. 267:8281-8285.
    • (1992) J. Biol. Chem. , vol.267 , pp. 8281-8285
    • Tremblay, G.B.1    Mejia, N.R.2    MacKenzie, R.E.3
  • 107
    • 0013827487 scopus 로고
    • Regulatory mechanisms of carbohydrate metabolim. VII. Hexokinase and phosphofructokinase
    • Uyeda K, Racker E (1965), Regulatory mechanisms of carbohydrate metabolim. VII. Hexokinase and phosphofructokinase, J. Biol. Chem. 240:4682-4688.
    • (1965) J. Biol. Chem. , vol.240 , pp. 4682-4688
    • Uyeda, K.1    Racker, E.2
  • 108
    • 0033588177 scopus 로고    scopus 로고
    • Incorporation of ammonium into intracellular UDP-activated N-acetylhexosamines and into carbohydrate structures in glycoproteins
    • Valley U, Nimtz M, Conradt HS, Wagner R (1999), Incorporation of ammonium into intracellular UDP-activated N-acetylhexosamines and into carbohydrate structures in glycoproteins, Biotechnol. Bioeng. 64:401-417.
    • (1999) Biotechnol. Bioeng. , vol.64 , pp. 401-417
    • Valley, U.1    Nimtz, M.2    Conradt, H.S.3    Wagner, R.4
  • 109
    • 0031554255 scopus 로고    scopus 로고
    • Effects of glutamine supply on growth and metabolism of mammalian cells in chemostat culture
    • Vriezen N, Romein B, Luyben KCAM, Van Dijken JP (1997), Effects of glutamine supply on growth and metabolism of mammalian cells in chemostat culture, Biotechnol Bioeng. 54:272-286.
    • (1997) Biotechnol Bioeng. , vol.54 , pp. 272-286
    • Vriezen, N.1    Romein, B.2    Luyben, K.C.A.M.3    Van Dijken, J.P.4
  • 110
    • 0026782099 scopus 로고
    • Cloning and expression of a hepatic microsomal glucose transport protein
    • Waddell ID, Zomerschoe AG, Voice MW, Burchell A (1992), Cloning and expression of a hepatic microsomal glucose transport protein, Biochem. J. 286:173-177.
    • (1992) Biochem. J. , vol.286 , pp. 173-177
    • Waddell, I.D.1    Zomerschoe, A.G.2    Voice, M.W.3    Burchell, A.4
  • 111
    • 85064693121 scopus 로고    scopus 로고
    • Metabolic control of animal cell culture processes
    • Hauser H, Wagner R (Eds), Walter de Gruyter, Berlin
    • Wagner R (1997), Metabolic control of animal cell culture processes. In: Hauser H, Wagner R (Eds), Mammalian Cell Biotechnology in Protein Production, Walter de Gruyter, Berlin, pp. 193-232.
    • (1997) Mammalian Cell Biotechnology in Protein Production , pp. 193-232
    • Wagner, R.1
  • 112
    • 0343329548 scopus 로고
    • Variation of amino acids concentrations in the medium of HU _-IFN and HU IL-2 producing cell lines
    • Wagner R, Ryll T, Krafft H, Lehmannm J (1988), Variation of amino acids concentrations in the medium of HU _-IFN and HU IL-2 producing cell lines, Cytotechnology 1:145-150.
    • (1988) Cytotechnology , vol.1 , pp. 145-150
    • Wagner, R.1    Ryll, T.2    Krafft, H.3    Lehmannm, J.4
  • 113
    • 0028708951 scopus 로고
    • Low temperature cultivation: a step towards process optimization
    • Weidemann R, Ludwig A, Kretzmer G (1994), Low temperature cultivation: a step towards process optimization, Cytotechnology 15:111-116.
    • (1994) Cytotechnology , vol.15 , pp. 111-116
    • Weidemann, R.1    Ludwig, A.2    Kretzmer, G.3
  • 115
    • 0036008002 scopus 로고    scopus 로고
    • Effects of ammonia and glucosamine on the heterogeneity of erythropoietin glycoforms
    • Yang M, Butler M (2002), Effects of ammonia and glucosamine on the heterogeneity of erythropoietin glycoforms, Biotechnol. Prog. 18:129-138.
    • (2002) Biotechnol. Prog. , vol.18 , pp. 129-138
    • Yang, M.1    Butler, M.2
  • 116
    • 0033589369 scopus 로고    scopus 로고
    • Bicarbonate concentration and osmolality are key determinants in the inhibition of CHO cell polysialylation under elevated pCO2 or pH
    • Zanghi JA, Schmeltzer AE, Mendoza TP, Knop RH, Miller WM (1999), Bicarbonate concentration and osmolality are key determinants in the inhibition of CHO cell polysialylation under elevated pCO2 or pH, Biotechnol Bioeng. 65:182-191.
    • (1999) Biotechnol Bioeng. , vol.65 , pp. 182-191
    • Zanghi, J.A.1    Schmeltzer, A.E.2    Mendoza, T.P.3    Knop, R.H.4    Miller, W.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.