A mutation of keratin 18 within the coil 1A consensus motif causes widespread keratin aggregation but cell type-restricted lethality in mice

Experimental Cell Research

Volumn 313, Issue 14, 2007, Pages 3127-3140

  Hesse, Michael ^a,b   Grund, Christine ^c   Herrmann, Harald ^c   Bröhl, Dominique ^a,d   Franz, Thomas ^a   Omary, M Bishr ^e   Magin, Thomas M ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF CALGARY   (Canada)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^e STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aggregates; Embryonic lethality; Intermediate filament; Keratin; Mutation

Indexed keywords

ARGININE; CYSTEINE; CYTOKERATIN 18; CYTOKERATIN 19; KERATIN;

ALLELE; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONSENSUS SEQUENCE; CONTROLLED STUDY; EMBRYO DEATH; GENE MUTATION; GIANT CELL; HEMATOMA; LETHALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN MOTIF; SEQUENCE ANALYSIS; TROPHOBLAST;

MUS;

EID: 34547222677     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2007.05.019     Document Type: Article

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