Distinct alterations in chromatin organization of the two IGF-I promoters precede growth hormone-induced activation of IGF-I gene transcription

Molecular Endocrinology

Volumn 24, Issue 4, 2010, Pages 779-789

  Chia, Dennis J ^a   Young, Jennifer J ^a   Mertens, April R ^a   Rotwein, Peter ^b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; HISTONE H3; HISTONE H4; LYSINE; MESSENGER RNA; PROTEIN P300; RECOMBINANT GROWTH HORMONE; RNA POLYMERASE II; SOMATOMEDIN C; SPACER DNA;

ACETYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CLINICAL ASSESSMENT; CONTROLLED STUDY; GENE EXPRESSION; GENE LOCUS; GROWTH HORMONE DEFICIENCY; HORMONAL REGULATION; HYPOPHYSECTOMY; INJECTION; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INDUCTION; PROTEIN METHYLATION; RAT; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE; TRANSCRIPTION INITIATION;

ACETYLATION; ANIMALS; BINDING SITES; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; GROWTH HORMONE; HISTONES; INSULIN-LIKE GROWTH FACTOR I; MALE; METHYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA POLYMERASE II; STAT5 TRANSCRIPTION FACTOR; TRANSCRIPTIONAL ACTIVATION;

RATTUS;

EID: 77950407463     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2009-0430     Document Type: Article

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