Development of an activity assay for discovery of inhibitors of lipopolysaccharide transport

Journal of the American Chemical Society

Volumn 132, Issue 8, 2010, Pages 2518-2519

  Gronenberg, Luisa S ^a,b   Kahne, Daniel ^a,b  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ACTIVITY ASSAYS; BIOCHEMICAL STUDIES; GRAM-NEGATIVE BACTERIA; HIGH-THROUGHPUT ASSAYS; KINASE INHIBITORS; LIPOPOLYSACCHARIDES; OUTER MEMBRANE; SMALL-MOLECULE INHIBITORS;

BACTERIA;

BACTERIOLOGY;

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; ANTIBIOTIC AGENT; BACTERIAL ENZYME; ENZYME INHIBITOR; GLUTAMIC ACID; GLUTAMINE; LIPOPOLYSACCHARIDE; MUTANT PROTEIN; ANTIINFECTIVE AGENT; ESCHERICHIA COLI PROTEIN; LPTB PROTEIN, E COLI;

ARTICLE; BACTERIAL GENE; BACTERIAL MEMBRANE; BIOGENESIS; CARBOHYDRATE SYNTHESIS; CHEMICAL REACTION; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE OVEREXPRESSION; HYDROLYSIS; LIPID MEMBRANE; LIPOGENESIS; MEMBRANE TRANSPORT; NONHUMAN; OUTER MEMBRANE; PROTEIN FUNCTION; PROTEIN STRUCTURE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL; UPREGULATION;

ANTI-BACTERIAL AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; LIPOPOLYSACCHARIDES; UP-REGULATION;

EID: 77950406664     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja910361r     Document Type: Article

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