Association of the OCA2 polymorphism His615Arg with melanin content in East Asian populations: Further evidence of convergent evolution of skin pigmentation

PLoS Genetics

Volumn 6, Issue 3, 2010, Pages

  Edwards, Melissa ^a   Bigham, Abigail ^b   Tan, Jinze ^c   Li, Shilin ^c   Gozdzik, Agnes ^a   Ross, Kendra ^a   Jin, Li ^c   Parra, Esteban J ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; GENE PRODUCT; HISTIDINE; MELANIN; PROTEIN ADAM17; PROTEIN ADAMTS20; PROTEIN DCT; PROTEIN OCA2; PROTEIN TYRP1; UNCLASSIFIED DRUG; CARRIER PROTEIN; OCA2 PROTEIN, HUMAN;

ALLELE; ARTICLE; CANADA; CHINESE; CONTROLLED STUDY; CONVERGENT EVOLUTION; GENE FREQUENCY; GENE LOCATION; GENE REPLICATION; GENETIC ASSOCIATION; HUMAN; QUANTITATIVE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN PIGMENTATION; AMINO ACID SUBSTITUTION; ASIAN; ETHNIC GROUP; EVOLUTION; GENETIC SELECTION; GENETICS; GENOTYPE; HAPLOTYPE; METABOLISM; STATISTICAL MODEL;

AMINO ACID SUBSTITUTION; ARGININE; ASIAN CONTINENTAL ANCESTRY GROUP; CANADA; ETHNIC GROUPS; EVOLUTION; GENE FREQUENCY; GENOTYPE; HAPLOTYPES; HISTIDINE; HUMANS; LINEAR MODELS; MELANINS; MEMBRANE TRANSPORT PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; SELECTION, GENETIC; SKIN PIGMENTATION;

EID: 77950385681     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000867     Document Type: Article

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