Determination of simvastatin-induced changes in bone composition and structure by Fourier transform infrared spectroscopy in rat animal model

Journal of Pharmaceutical and Biomedical Analysis

Volumn 52, Issue 4, 2010, Pages 580-588

  Garip, Sebnem ^a   Severcan, Feride ^a  

^a MIDDLE EAST TECHNICAL UNIVERSITY   (Turkey)

Author keywords

Bone; Cluster analysis; FTIR; Lipid peroxidation; Relative carbonate content; Simvastatin

Indexed keywords

AMIDE; CARBONIC ACID; LIPID; PHOSPHATE; SIMVASTATIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MINERAL; BONE STRENGTH; BONE STRUCTURE; BONE TISSUE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; INFRARED SPECTROSCOPY; LIPID COMPOSITION; LIPID PEROXIDATION; LOW DRUG DOSE; MALE; NONHUMAN; PHYSICAL PARAMETERS; PRIORITY JOURNAL; RAT; TIBIA; ANIMAL; ANIMAL MODEL; BONE DENSITY; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; PROCEDURES; WISTAR RAT;

ANIMALS; BONE DENSITY; MALE; MODELS, ANIMAL; RATS; RATS, WISTAR; SIMVASTATIN; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TIBIA;

EID: 77950368113     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.01.044     Document Type: Article

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