FT-IR imaging of native and tissue-engineered bone and cartilage

Biomaterials

Volumn 28, Issue 15, 2007, Pages 2465-2478

  Boskey, Adele ^a   Pleshko Camacho, Nancy ^a  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

Bone; Bone tissue engineering; Cartilage tissue engineering; Cartilage vibrational spectroscopy; Review

Indexed keywords

BONE TISSUE ENGINEERING; CARTILAGE TISSUE ENGINEERING; CARTILAGE VIBRATIONAL SPECTROSCOPY; OSTEOPOROSIS; REVIEW;

BONE; CARTILAGE; DISEASES; FOURIER TRANSFORM INFRARED SPECTROSCOPY; HEALTH CARE; PATHOLOGY;

TISSUE ENGINEERING;

SYNTHETIC PEPTIDE; TP 508; UNCLASSIFIED DRUG;

AGE DETERMINATION; BONE; BONE EXAMINATION; BONE STRUCTURE; CARTILAGE; CARTILAGE DEGENERATION; HUMAN; IMAGE ANALYSIS; IMAGING SYSTEM; INFRARED SPECTROSCOPY; MICROSCOPY; MONITORING; NONHUMAN; PRIORITY JOURNAL; REVIEW; TISSUE ENGINEERING; TISSUE REPAIR;

ANIMALS; BONE AND BONES; CARTILAGE; COLLAGEN; DIAGNOSTIC IMAGING; HUMANS; PROTEOGLYCANS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TISSUE ENGINEERING;

EID: 33847621211     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2006.11.043     Document Type: Review

References (122)

1. Boskey A., and Mendelsohn R. Infrared analysis of bone in health and disease. J Biomed Opt 10 (2005) 031102-031106
2. Carden A., and Morris M.D. Application of vibrational spectroscopy to the study of mineralized tissues. J Biomed Opt 5 (2000) 259-268
3. Miller L.M., and Dumas P. Chemical imaging of biological tissue with synchrotron infrared light. Biochim Biophys Acta 1758 (2006) 846-857
4. West P.A., Bostrom M.P., Torzilli P.A., and Camacho N.P. Fourier transform infrared spectral analysis of degenerative cartilage: an infrared fiber optic probe and imaging study. Appl Spectrosc 58 (2004) 376-381
5. Barer R., Cole A.R.H., and Thompson H.W. Infrared spectroscopy with the reflecting microscope in physics, chemistry and biology. Nature 163 (1949) 198-201
6. Mendelsohn R., Hassankhani A., DiCarlo E., and Boskey A. FT-IR microscopy of endochondral ossification at 20 μ spatial resolution. Calcif Tissue Int 44 (1989) 20-24
7. Rintoul L., Panayiotou H., Kokot S., George G., Cash G., Frost R., et al. Fourier transform infrared spectrometry: a versatile technique for real world samples. Analyst 123 (1998) 571-577
8. Manoharan R., Baraga J.J., Rava R.P., Dasari R.R., Fitzmaurice M., and Feld M.S. Biochemical analysis and mapping of atherosclerotic human artery using FT-IR microspectroscopy. Atherosclerosis 103 (1993) 181-193
9. Choo L.P., Wetzel D.L., Halliday W.C., Jackson M., LeVine S.M., and Mantsch H.H. In situ characterization of beta-amyloid in Alzheimer's diseased tissue by synchrotron Fourier transform infrared microspectroscopy. Biophys J 71 (1996) 1672-1679
10. Diem M., Chiriboga L., and Yee H. Infrared spectroscopy of human cells and tissue. VIII. Strategies for analysis of infrared tissue mapping data and applications to liver tissue. Biopolymers 57 (2000) 282-290
11. Lasch P., Pacifico A., and Diem M. Spatially resolved IR microspectroscopy of single cells. Biopolymers 67 (2002) 335-338
12. Kalasinsky K.S., and Kalasinsky V.F. Infrared and Raman microspectroscopy of foreign materials in tissue specimens. Spectrochim Acta A Mol Biomol Spectrosc 61 (2005) 1707-1713
13. Pachman L.M., Veis A., Stock S., Abbott K., Vicari F., Patel P., et al. Composition of calcifications in children with juvenile dermatomyositis: association with chronic cutaneous inflammation. Arthritis Rheum 54 (2006) 3345-3350
14. Lewis E.N., Treado P.J., Reeder R.C., Story G.M., Dowrey A.E., Marcott C., et al. Fourier transform spectroscopic imaging using an infrared focal-plane array detector. Anal Chem 67 (1995) 3377-3381
15. Marcott C., Reeder R.C., Paschalis E.P., Tatakis D.N., Boskey A.L., and Mendelsohn R. Infrared microspectroscopic imaging of biomineralized tissues using a mercury-cadmium-telluride focal-plane array detector. Cell Mol Biol (Noisy-le-grand) 44 (1998) 109-115
16. Miller L.M., and Smith R.J. Synchrotrons versus globars, point-detectors versus focal plane arrays: selecting the best source and detector for specific infrared microscopy and imaging applications. Vib Spec 38 (2005) 237-240
17. Levin I.W., and Bhargava R. Fourier transform infrared vibrational spectroscopic imaging: integrating microscopy and molecular recognition. Annu Rev Phys Chem 56 (2005) 429-474
18. Boskey A.L. Bone mineralization. In: Cowin S.C. (Ed). Bone biomechanics. 3rd ed (2001), CRC Press, Boca Raton, FL 5.1-5.34
19. Fowler B.O., Moreno E.C., and Brown W.E. Infra-red spectra of hydroxyapatite, octacalcium phosphate and pyrolysed octacalcium phosphate. Arch Oral Biol 11 (1966) 477-492
20. 4 domain. Calcif Tissue Int 46 (1990) 384-394
21. Walters M.A., Leung Y.C., Blumenthal N.C., LeGeros R.Z., and Konsker K.A. A Raman and infrared spectroscopic investigation of biological hydroxyapatite. J Inorg Biochem 39 (1990) 193-200
22. Lazarev Y.A., Grishkovsky B.A., and Khromova T.B. Amide I band of IR spectrum and structure of collagen and related polypeptides. Biopolymers 24 (1985) 1449-1478
23. Juszczak L.J. Comparative vibrational spectroscopy of intracellular tau and extracellular collagen I reveals parallels of gelation and fibrillar structure. J Biol Chem 279 (2004) 7395-7404
24. Rey C., Collins B., Goehl T., Dickson I.R., and Glimcher M.J. The carbonate environment in bone mineral: a resolution-enhanced Fourier Transform Infrared Spectroscopy Study. Calcif Tissue Int 45 (1989) 157-164
25. Boskey A.L., Moore D.J., Amling M., Canalis E., and Delany A.M. Infrared analysis of the mineral and matrix in bones of osteonectin-null mice and their wildtype controls. J Bone Miner Res 18 (2003) 1005-1011
26. Aparicio S., Doty S.B., Camacho N.P., Paschalis E.P., Spevak L., Mendelsohn R., et al. Optimal methods for processing mineralized tissues for Fourier transform infrared microspectroscopy. Calcif Tissue Int 70 (2002) 422-429
27. Gadaleta S.J., Boskey A.L., Paschalis E., Carlson C., Menschik F., Baldini T., et al. A physical, chemical, and mechanical study of lumbar vertebrae from normal, ovariectomized, and nandrolone decanoate-treated cynomolgus monkeys (Macaca fascicularis). Bone 27 (2000) 541-550
28. Ouyang H., Sherman P.J., Paschalis E.P., Boskey A.L., and Mendelsohn R. Fourier transform infrared microscopic imaging: effects of estrogen and estrogen deficiency on fracture healing in rat femurs. Appl Spectrosc 58 (2004) 1-9
29. Verberckmoes S.C., Behets G.J., Oste L., Bervoets A.R., Lamberts L.V., Drakopoulos M., et al. Effects of strontium on the physicochemical characteristics of hydroxyapatite. Calcif Tissue Int 75 (2004) 405-415
30. Masse P.G., Rimnac C.M., Yamauchi M., Coburn S.P., Rucker R.B., Howell D.S., et al. Pyridoxine deficiency affects biomechanical properties of chick tibial bone. Bone 18 (1996) 567-574
31. Kim H.M., Rey C., and Glimcher M.J. Isolation of calcium-phosphate crystals of bone by non-aqueous methods at low temperature. J Bone Miner Res 10 (1995) 1589-1601
32. Pienkowski D., Doers T.M., Monier-Faugere M.C., Geng Z., Camacho N.P., Boskey A.L., et al. Calcitonin alters bone quality in beagle dogs. J Bone Miner Res 12 (1997) 1936-1943
33. Burr D.B., Miller L., Grynpas M., Li J., Boyde A., Mashiba T., et al. Tissue mineralization is increased following 1-year treatment with high doses of bisphosphonates in dogs. Bone 33 (2003) 960-969
34. Paschalis E.P., Burr D.B., Mendelsohn R., Hock J.M., and Boskey A.L. Bone mineral and collagen quality in humeri of ovariectomized cynomolgus monkeys given rhPTH (1-34) for 18 months. J Bone Miner Res 18 (2003) 769-775
35. Paschalis E.P., Jacenko O., Olsen B., Mendelsohn R., and Boskey A.L. Fourier transform infrared microspectroscopic analysis identifies alterations in mineral properties in bones from mice transgenic for type X collagen. Bone 19 (1996) 151-156
36. Boskey A.L., Gadaleta S., Gundberg C., Doty S.B., Ducy P., and Karsenty G. Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin. Bone 23 (1998) 187-196
37. Camacho N.P., Rimnac C.M., Meyer Jr. R.A., Doty S., and Boskey A.L. Effect of abnormal mineralization on the mechanical behavior of X-linked hypophosphatemic mice femora. Bone 17 (1995) 271-278
38. Camacho N.P., Carroll P., and Raggio C.L. Fourier transform infrared imaging spectroscopy (FT-IRIS) of mineralization in bisphosphonate-treated oim/oim mice. Calcif Tissue Int 72 (2003) 604-609
39. Camacho N.P., Landis W.J., and Boskey A.L. Mineral changes in a mouse model of osteogenesis imperfecta detected by Fourier transform infrared microscopy. Connect Tissue Res 35 (1996) 259-265
40. Boskey A.L., Spevak L., Paschalis E., Doty S.B., and McKee M.D. Osteopontin deficiency increases mineral content and mineral crystallinity in mouse bone. Calcif Tissue Int 71 (2002) 145-154
41. Atti E., Gomez S., Wahl S.M., Mendelsohn R., Paschalis E., and Boskey A.L. Effects of transforming growth factor-beta deficiency on bone development: a Fourier transform-infrared imaging analysis. Bone 31 (2002) 675-684
42. Misof B.M., Roschger P., Tesch W., Baldock P.A., Valenta A., Messmer P., et al. Targeted overexpression of vitamin D receptor in osteoblasts increases calcium concentration without affecting structural properties of bone mineral crystals. Calcif Tissue Int 73 (2003) 251-257
43. Anderson H.C., Sipe J.B., Hessle L., Dhanyamraju R., Atti E., Camacho N.P., et al. Impaired calcification around matrix vesicles of growth plate and bone in alkaline phosphatase-deficient mice. Am J Pathol 164 (2004) 841-847
44. Atti E., Boskey A.L., and Canalis E. Overexpression of IGF-binding protein 5 alters mineral and matrix properties in mouse femora: an infrared imaging study. Calcif Tissue Int 76 (2005) 187-193
45. Ling Y., Rios H.F., Myers E.R., Lu Y., Feng J.Q., and Boskey A.L. DMP1 depletion decreases bone mineralization in vivo: an FTIR imaging analysis. J Bone Miner Res 20 (2005) 2169-2177
46. Xu T., Bianco P., Fisher L.W., Longenecker G., Smith E., Goldstein S., et al. Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice. Nat Genet 20 (1998) 78-82
47. Boskey A.L., Goldberg M., Kulkarni A., and Gomez S. Infrared imaging microscopy of bone: illustrations from a mouse model of Fabry disease. Biochim Biophys Acta 1758 (2006) 942-947
48. Boskey A.L. Bone mineral crystal size. Osteoporos Int 14 S5 (2003) 16-21
49. Paschalis E.P., Betts F., DiCarlo E., Mendelsohn R., and Boskey A.L. FTIR micro-spectroscopic analysis of human iliac crest biopsies from untreated osteoporotic bone. Calcif Tissue Int 61 (1997) 487-492
50. Boskey A.L., DiCarlo E., Paschalis E., West P., and Mendelsohn R. Comparison of mineral quality and quantity in iliac crest biopsies from high- and low-turnover osteoporosis: an FT-IR microspectroscopic investigation. Osteoporos Int 16 (2005) 2031-2038
51. Huang R.Y., Miller L.M., Carlson C.S., and Chance M.R. In situ chemistry of osteoporosis revealed by synchrotron infrared microspectroscopy. Bone 33 (2003) 514-521
52. Faibish D., Ott S.M., and Boskey A.L. Mineral changes in osteoporosis: a review. Clin Orthop Relat Res 443 (2006) 28-38
53. Faibish D., Gomes A., Boivin G., Binderman I., and Boskey A. Infrared imaging of calcified tissue in bone biopsies from adults with osteomalacia. Bone 36 (2005) 6-12
54. Boskey A. Mineral changes in osteopetrosis. Crit Rev Eukaryot Gene Exp 13 (2003) 109-116
55. Boskey A, Mendelsohn R, referenced above Boskey AL. Assessment of bone mineral and matrix using backscatter electron imaging and FTIR imaging. Curr Osteoporos Rep 2006;4:71-75.
56. Ruppel M.E., Burr D.B., and Miller L.M. Chemical makeup of microdamaged bone differs from undamaged bone. Bone 39 (2006) 318-324
57. Zhang Y., and Zhang M. Three-dimensional macroporous calcium phosphate bioceramics with nested chitosan sponges for load-bearing bone implants. J Biomed Mater Res 61 (2002) 1-8
58. Dekker R.J., de Bruijn J.D., Stigter M., Barrere F., Layrolle P., and van Blitterswijk C.A. Bone tissue engineering on amorphous carbonated apatite and crystalline octacalcium phosphate-coated titanium discs. Biomaterials 26 (2005) 5231-5239
59. Li J., Yun H., Gong Y., Zhao N., and Zhang X. Investigation of MC3T3-E1 cell behavior on the surface of GRGDS-coupled chitosan. Biomacromolecules 7 (2006) 1112-1123
60. Verma D., Katti K., and Katti D. Bioactivity in in situ hydroxyapatite-polycaprolactone composites. J Biomed Mater Res A 78 (2006) 772-780
61. Boyan B.D., Bonewald L.F., Paschalis E.P., Lohmann C.H., Rosser J., Cochran D.L., et al. Osteoblast-mediated mineral deposition in culture is dependent on surface microtopography. Calcif Tissue Int 71 (2002) 519-529
62. Halvorsen Y.D., Franklin D., Bond A.L., Hitt D.C., Auchter C., Boskey A.L., et al. Extracellular matrix mineralization and osteoblast gene expression by human adipose tissue-derived stromal cells. Tissue Eng 7 (2001) 729-741
63. Toworfe G.K., Composto R.J., Shapiro I.M., and Ducheyne P. Nucleation and growth of calcium phosphate on amine-, carboxyl- and hydroxyl-silane self-assembled monolayers. Biomaterials 27 (2006) 631-642
64. Weiss P., Bohic S., Lapkowski M., and Daculsi G. Application of FT-IR microspectroscopy to the study of an injectable composite for bone and dental surgery. J Biomed Mater Res 41 (1998) 167-170
65. Skrtic D., Antonucci J.M., Eanes E.D., and Eidelman N. Dental composites based on hybrid and surface-modified amorphous calcium phosphates. Biomaterials 25 (2004) 1141-1150
66. Schmitt M., Weiss P., Bourges X., Amador del Valle G., and Daculsi G. Crystallization at the polymer/calcium-phosphate interface in a sterilized injectable bone substitute IBS. Biomaterials 23 (2002) 2789-2794
67. Kazarian S.G., Chan K.L., Maquet V., and Boccaccini A.R. Characterisation of bioactive and resorbable polylactide/Bioglass composites by FTIR spectroscopic imaging. Biomaterials 25 (2004) 3931-3938
68. Huber M., Trattnig S., and Lintner F. Anatomy, biochemistry, and physiology of articular cartilage. Invest Radiol 35 (2000) 573-580
69. Goldring M.B. The musculoskeletal system: articular cartilage. In: Klippel J.H., Weyand C.M., and Wortmann R.L. (Eds). Primer on the rheumatic diseases (1997), The Arthritis Foundation, Atlanta 14-18
70. Aydelotte M.B., Greenhill R.R., and Kuettner K.E. Differences between sub-populations of cultured bovine articular chondrocytes. II. Proteoglycan metabolism. Connect Tissue Res 18 (1988) 223-234
71. Aydelotte M.B., and Kuettner K.E. Differences between sub-populations of cultured bovine articular chondrocytes. I. Morphology and cartilage matrix production. Connect Tissue Res 18 (1988) 205-222
72. Iannone F., and Lapadula G. The pathophysiology of osteoarthritis. Aging Clin Exp Res 15 (2003) 364-372
73. Malemud C.J., Islam N., and Haqqi T.M. Pathophysiological mechanisms in osteoarthritis lead to novel therapeutic strategies. Cells Tissues Organs 174 (2003) 34-48
74. Mort J.S., and Billington C.J. Articular cartilage and changes in arthritis: matrix degradation. Arthritis Res 3 (2001) 337-341
75. Jackson D.W., Simon T.M., and Aberman H.M. Symptomatic articular cartilage degeneration: the impact in the new millennium. Clin Orthop Relat Res (2001) S14-S25
76. Mithoefer K., Williams III R.J., Warren R.F., Potter H.G., Spock C.R., Jones E.C., et al. The microfracture technique for the treatment of articular cartilage lesions in the knee. A prospective cohort study. J Bone Joint Surg Am 87 (2005) 1911-1920
77. Gudas R., Stankevicius E., Monastyreckiene E., Pranys D., and Kalesinskas R.J. Osteochondral autologous transplantation versus microfracture for the treatment of articular cartilage defects in the knee joint in athletes. Knee Surg Sports Traumatol Arthrosc 14 (2006) 834-842
78. Bae D.K., Yoon K.H., and Song S.J. Cartilage healing after microfracture in osteoarthritic knees. Arthroscopy 22 (2006) 367-374
79. Mithoefer K., Williams III R.J., Warren R.F., Wickiewicz T.L., and Marx R.G. High-impact athletics after knee articular cartilage repair: a prospective evaluation of the microfracture technique. Am J Sports Med 34 (2006) 1413-1418
80. Kuo A.C., Rodrigo J.J., Reddi A.H., Curtiss S., Grotkopp E., and Chiu M. Microfracture and bone morphogenetic protein 7 (BMP-7) synergistically stimulate articular cartilage repair. Osteoarthritis Cartilage 14 (2006) 1126-1135
81. Pennock A.T., Robertson C.M., Wagner F., Harwood F.L., Bugbee W.D., and Amiel D. Does subchondral bone affect the fate of osteochondral allografts during storage?. Am J Sports Med 34 (2006) 586-591
82. Glenn Jr. R.E., McCarty E.C., Potter H.G., Juliao S.F., Gordon J.D., and Spindler K.P. Comparison of fresh osteochondral autografts and allografts: a canine model. Am J Sports Med 34 (2006) 1084-1093
83. Alford J.W., and Cole B.J. Cartilage restoration, part 2: techniques, outcomes, and future directions. Am J Sports Med 33 (2005) 443-460
84. Ginat D.T., Kenan S., and Steiner G.C. Osteoarticular allograft of the proximal humerus-histopathological study 18 years after implantation. Acta Orthop 76 (2005) 934-938
85. Malinin T., Temple H.T., and Buck B.E. Transplantation of osteochondral allografts after cold storage. J Bone Joint Surg Am 88 (2006) 762-770
86. Amin A.A., Bartlett W., Gooding CR Sood M., Skinner J.A., Carrington R.W., Briggs T.W., et al. The use of autologous chondrocyte implantation following and combined with anterior cruciate ligament reconstruction. Int Orthop 30 (2006) 48-53
87. Krishnan S.P., Skinner J.A., Carrington R.W., Flanagan A.M., Briggs T.W., and Bentley G. Collagen-covered autologous chondrocyte implantation for osteochondritis dissecans of the knee: two- to seven-year results. J Bone Joint Surg Br 88 (2006) 203-205
88. Gooding C.R., Bartlett W., Bentley G., Skinner J.A., Carrington R., and Flanagan A. A prospective, randomised study comparing two techniques of autologous chondrocyte implantation for osteochondral defects in the knee: periosteum covered versus type I/III collagen covered. Knee 13 (2006) 203-210
89. Wasiak J., Clar C., and Villanueva E. Autologous cartilage implantation for full thickness articular cartilage defects of the knee. Cochrane Database Syst Rev 3 (2006) CD003323
90. Roberts S., Hollander A.P., Caterson B., Menage J., and Richardson J.B. Matrix turnover in human cartilage repair tissue in autologous chondrocyte implantation. Arthritis Rheum 44 (2001) 2586-2598
91. Gemmiti C.V., and Guldberg R.E. Fluid flow increases type II collagen deposition and tensile mechanical properties in bioreactor-grown tissue-engineered cartilage. Tissue Eng 12 (2006) 469-479
92. Mahmoudifar N., and Doran P.M. Effect of seeding and bioreactor culture conditions on the development of human tissue-engineered cartilage. Tissue Eng 12 (2006) 1675-1685
93. Potter K., Butler J.J., Adams C Fishbein K.W., McFarland E.W., Horton W.E., and Spencer R.G. Cartilage formation in a hollow fiber bioreactor studied by proton magnetic resonance microscopy. Matrix Biol 17 (1998) 513-523
94. Potter K., Fishbein K.W., Horton W.E., and Spencer R.G. Morphometric analysis of cartilage grown in a hollow fiber bioreactor using NMR microscopy. In: Blümler P., Blümlich B., Botto R., and Fukushima E. (Eds). Spatially resolved magnetic resonance (1998), Wiley-VCH Press, Weinheim 363-371
95. Huin-Amargier C., Marchal P., Payan E., Netter P., and Dellacherie E. New physically and chemically crosslinked hyaluronate (HA)-based hydrogels for cartilage repair. J Biomed Mater Res A 76 (2006) 416-424
96. Yamaoka H., Asato H., Ogasawara T., Nishizawa S., Takahashi T., Nakatsuka T., et al. Cartilage tissue engineering using human auricular chondrocytes embedded in different hydrogel materials. J Biomed Mater Res A 78 (2006) 1-11
97. Montembault A., Tahiri K., Korwin-Zmijowska C., Chevalier X., Corvol M.T., and Domard A. A material decoy of biological media based on chitosan physical hydrogels: application to cartilage tissue engineering. Biochimie 88 (2006) 551-564
98. Vinatier C., Guicheux J., Daculsi G., Layrolle P., and Weiss P. Cartilage and bone tissue engineering using hydrogels. Biomed Mater Eng 16 (2006) S107-S113
99. 2O demonstrates that collagen monomers undergo a conformational transition prior to thermal self-assembly in vitro. Biochemistry 30 (1991) 2372-2377
100. Lazarev Y.A., Grishkovsky B.A., and Khromova T.B. Amide I band of IR spectrum and structure of collagen and related polypeptides. Biopolymers 24 (1985) 1449-1478
101. Lazarev Y.A., Grishkovsky B.A., Khromova T.B., Lazareva A.V., and Grechishko V.S. Bound water in collagen-like triple helical structure. Biopolymers 32 (1992) 189-195
102. Bychkov S.M., Bogatov V.N., and Kuz'mina S.A. Study of different proteoglycan salts. Biull Eksp Biol Med 92 (1981) 302-305
103. Bychkov S.M., and Kuz'mina S.A. Study of eye proteoglycans by means of infrared spectroscopy. Biull Eksp Biol Med 111 (1991) 475-477
104. Bychkov S.M., and Kuz'mina S.A. Study of tissue proteoglycans by means of infrared spectroscopy. Biull Eksp Biol Med 114 (1992) 246-249
105. Camacho N.P., West P., Torzilli P.A., and Mendelsohn R. FTIR microscopic imaging of collagen and proteoglycan in bovine cartilage. Biopolymers 62 (2001) 1-8
106. Potter K., Kidder L.H., Levin I.W., Lewis E.N., and Spencer R.G. Imaging of collagen and proteoglycan in cartilage sections using Fourier transform infrared spectral imaging. Arthritis Rheum 44 (2001) 846-855
107. Kim M., Bi X., Horton W.E., Spencer R.G., and Camacho N.P. Fourier transform infrared imaging spectroscopic analysis of tissue engineered cartilage: histologic and biochemical correlations. J Biomed Opt 10 (2005) 031105
108. Bi X., Li G., Doty S.B., and Camacho N.P. A novel method for determination of collagen orientation in cartilage by Fourier transform infrared imaging spectroscopy (FT-IRIS). Osteoarthritis Cartilage 13 (2005) 1050-1058
109. Jackson M., Choo L.P., Watson P.H., Halliday W.C., and Mantsch H.H. Beware of connective tissue proteins: assignment and implications of collagen absorptions in infrared spectra of human tissues. Biochim Biophys Acta 1270 (1995) 1-6
110. West P.A., Torzilli P.A., Chen C., Lin P., and Camacho N.P. Fourier transform infrared imaging spectroscopy analysis of collagenase-induced cartilage degradation. J Biomed Opt 10 (2005) 14015
111. Kiviranta P., Rieppo J., Korhonen R.K., Julkunen P., Toyras J., and Jurvelin J.S. Collagen network primarily controls Poisson's ratio of bovine articular cartilage in compression. J Orthop Res 24 (2006) 690-699
112. Korhonen R.K., Julkunen P., Rieppo J., Lappalainen R., Konttinen Y.T., and Jurvelin J.S. Collagen network of articular cartilage modulates fluid flow and mechanical stresses in chondrocyte. Biomech Model Mechanobiol 5 (2006) 150-159
113. David-Vaudey E., Burghardt A., Keshari K., Brouchet A., Ries M., and Majumdar S. Fourier transform infrared imaging of focal lesions in human osteoarthritic cartilage. Eur Cell Mater 10 (2005) 51-60
114. Bi X., Yang X., Bostrom M.P., and Camacho N.P. Fourier transform infrared imaging spectroscopy investigations in the pathogenesis and repair of cartilage. Biochim Biophys Acta 1758 (2006) 934-941
115. Kim M, Hidaka C, Cheng C, Ramaswamy S, Spencer RG, Camacho NP. Development and analysis of tissue-engineered mammalian cartilage in a hollow-fiber bioreactor: FTIR spectroscopic and gene expression studies. In: Sixth symposium of the International Cartilage Repair Society, 2006. p. 3-5 (abstr.).
116. Dorotka R., Windberger U., Macfelda K., Bindreiter U., Toma C., and Nehrer S. Repair of articular cartilage defects treated by microfracture and a three-dimensional collagen matrix. Biomaterials 26 (2005) 3617-3629
117. Gill T.J., McCulloch P.C., Glasson S.S., Blanchet T., and Morris E.A. Chondral defect repair after the microfracture procedure: a nonhuman primate model. Am J Sports Med 33 (2005) 680-685
118. Litzke L.E., Wagner E., Baumgaertner W., Hetzel U., Josimovic-Alasevic O., and Libera J. Repair of extensive articular cartilage defects in horses by autologous chondrocyte transplantation. Ann Biomed Eng 32 (2004) 57-69
119. Potter HG, Foo LF, Tamaroff E, Lyman S, Camacho NP, Kim M, et al. MRI, Quantitative T2 mapping and FT-IRIS of cartilage repair using a synthetic thrombin receptor-based peptide (TP-508). In: A rabbit model: sixth symposium of the International Cartilage Repair Society, 2006. p. 3-37 (abstr.).
120. Kim M, Charlton D, Doty SB, Camacho NP, Maher SA. Distribution of PLGA and PVA in hydrogels as determined by Fourier transform infrared imaging spectroscopy (FT-IRIS). In: Sixth symposium of the International Cartilage Repair Society, 2006. p. 3-54 (abstr.).
121. Mendelsohn R., Flach C.R., and Moore D.J. Determination of molecular conformation and permeation in skin via IR spectroscopy, microscopy, and imaging. Biochim Biophys Acta 1758 (2006) 923-933
122. Li G., Thomson M., Dicarlo E., Yang X., Nestor B., Bostrom M.P., et al. A chemometric analysis for evaluation of early-stage cartilage degradation by infrared fiber-optic probe spectroscopy. Appl Spectrosc 59 (2005) 1527-1533