Critical amino acids in human DNA polymerases η and κ involved in erroneous incorporation of oxidized nucleotides

Nucleic Acids Research

Volumn 38, Issue 3, 2009, Pages 859-867

  Katafuchi, Atsushi ^a   Sassa, Akira ^a,b   Niimi, Naoko ^a   Grúz, Petr ^a   Fujimoto, Hirofumi ^c   Masutani, Chikahide ^d   Hanaoka, Fumio ^e   Ohta, Toshihiro ^b   Nohmi, Takehiko ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^d OSAKA UNIVERSITY   (Japan)

^e GAKUSHUIN UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; ALANINE; ARGININE; ASPARAGINE; CYTOSINE; DEOXYGUANOSINE TRIPHOSPHATE; DNA DIRECTED DNA POLYMERASE; DNA DIRECTED DNA POLYMERASE ETA; DNA DIRECTED DNA POLYMERASE KAPPA; GLUTAMINE; GUANINE; HISTIDINE; LYSINE; METHIONINE; PHENYLALANINE; SERINE; TYROSINE; UNCLASSIFIED DRUG; 8 OXODEOXYGUANOSINE TRIPHOSPHATE; 8-OXODEOXYGUANOSINE TRIPHOSPHATE; DEOXYADENOSINE DERIVATIVE; DEOXYGUANOSINE PHOSPHATE; DNA; POLK PROTEIN, HUMAN;

AMINO ACID ANALYSIS; AMINO ACID SUBSTITUTION; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DNA CONFORMATION; ENZYME ACTIVE SITE; MOLECULAR MECHANICS; MUTAGENESIS; NUCLEIC ACID BASE SUBSTITUTION; OXIDATION; PRIORITY JOURNAL; BASE PAIRING; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; KINETICS; METABOLISM; OXIDATION REDUCTION REACTION;

AMINO ACID SUBSTITUTION; ARGININE; BASE PAIRING; CATALYTIC DOMAIN; DEOXYADENOSINES; DEOXYGUANINE NUCLEOTIDES; DNA; DNA-DIRECTED DNA POLYMERASE; HUMANS; KINETICS; MODELS, MOLECULAR; OXIDATION-REDUCTION;

EID: 77950357011     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkp1095     Document Type: Article

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