-
1
-
-
33646188173
-
Major advances associated with hormone and growth factor regulation of mammary growth and lactation in dairy cows
-
Akers R.M. Major advances associated with hormone and growth factor regulation of mammary growth and lactation in dairy cows. J Dairy Sci. 89 (2006) 1222-1234
-
(2006)
J Dairy Sci.
, vol.89
, pp. 1222-1234
-
-
Akers, R.M.1
-
2
-
-
0033214948
-
Bovine somatotropin and lactation: from basic science to commercial application
-
Bauman D.E. Bovine somatotropin and lactation: from basic science to commercial application. Domest Anim Endocrinol. 17 (1999) 101-116
-
(1999)
Domest Anim Endocrinol.
, vol.17
, pp. 101-116
-
-
Bauman, D.E.1
-
3
-
-
0026728771
-
Receptor binding and growth-promoting activity of insulin-like growth factor-I in a bovine mammary epithelial cell line (MAC-T3)
-
Zhao X., McBride B.W., Politis I., Huynh H.T., Akers R.M., Burton J.H., and Turner J.D. Receptor binding and growth-promoting activity of insulin-like growth factor-I in a bovine mammary epithelial cell line (MAC-T3). J Endocrinol. 134 (1992) 307-312
-
(1992)
J Endocrinol.
, vol.134
, pp. 307-312
-
-
Zhao, X.1
McBride, B.W.2
Politis, I.3
Huynh, H.T.4
Akers, R.M.5
Burton, J.H.6
Turner, J.D.7
-
4
-
-
33751551462
-
Insulin growth factor-I and epidermal growth factor receptors recruit distinct upstream signaling molecules to enhance AKT activation in mammary epithelial cells
-
Fleming J.M., Desury G., Polanco T.A., and Cohick W.S. Insulin growth factor-I and epidermal growth factor receptors recruit distinct upstream signaling molecules to enhance AKT activation in mammary epithelial cells. Endocrinology. 147 (2006) 6027-6035
-
(2006)
Endocrinology.
, vol.147
, pp. 6027-6035
-
-
Fleming, J.M.1
Desury, G.2
Polanco, T.A.3
Cohick, W.S.4
-
5
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger S., Loewith R., and Hall M.N. TOR signaling in growth and metabolism. Cell. 124 (2006) 471-484
-
(2006)
Cell.
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
6
-
-
45949102297
-
The mammalian target of rapamycin-signaling pathway in regulating metabolism and growth
-
Yang X., Yang C., Farberman A., Rideout T.C., de Lange C.F., France J., and Fan M.Z. The mammalian target of rapamycin-signaling pathway in regulating metabolism and growth. J Anim Sci. 86 (2008) E36-50
-
(2008)
J Anim Sci.
, vol.86
-
-
Yang, X.1
Yang, C.2
Farberman, A.3
Rideout, T.C.4
de Lange, C.F.5
France, J.6
Fan, M.Z.7
-
7
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
Inoki K., Li Y., Zhu T., Wu J., and Guan K.L. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol. 4 (2002) 648-657
-
(2002)
Nat Cell Biol.
, vol.4
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.L.5
-
8
-
-
0036342294
-
Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway
-
Manning B.D., Tee A.R., Logsdon M.N., Blenis J., and Cantley L.C. Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway. Mol Cell. 10 (2002) 151-162
-
(2002)
Mol Cell.
, vol.10
, pp. 151-162
-
-
Manning, B.D.1
Tee, A.R.2
Logsdon, M.N.3
Blenis, J.4
Cantley, L.C.5
-
9
-
-
0037108750
-
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling
-
Tee A.R., Fingar D.C., Manning B.D., Kwiatkowski D.J., Cantley L.C., and Blenis J. Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling. Proc Natl Acad Sci U S A. 99 (2002) 13571-13576
-
(2002)
Proc Natl Acad Sci U S A.
, vol.99
, pp. 13571-13576
-
-
Tee, A.R.1
Fingar, D.C.2
Manning, B.D.3
Kwiatkowski, D.J.4
Cantley, L.C.5
Blenis, J.6
-
10
-
-
0043127125
-
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
-
Inoki K., Li Y., Xu T., and Guan K.L. Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling. Genes Dev. 17 (2003) 1829-1834
-
(2003)
Genes Dev.
, vol.17
, pp. 1829-1834
-
-
Inoki, K.1
Li, Y.2
Xu, T.3
Guan, K.L.4
-
11
-
-
0042701991
-
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
-
Tee A.R., Manning B.D., Roux P.P., Cantley L.C., and Blenis J. Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb. Curr Biol. 13 (2003) 1259-1268
-
(2003)
Curr Biol.
, vol.13
, pp. 1259-1268
-
-
Tee, A.R.1
Manning, B.D.2
Roux, P.P.3
Cantley, L.C.4
Blenis, J.5
-
12
-
-
33947264077
-
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase
-
Sancak Y., Thoreen C.C., Peterson T.R., Lindquist R.A., Kang S.A., Spooner E., Carr S.A., and Sabatini D.M. PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase. Mol Cell. 25 (2007) 903-915
-
(2007)
Mol Cell.
, vol.25
, pp. 903-915
-
-
Sancak, Y.1
Thoreen, C.C.2
Peterson, T.R.3
Lindquist, R.A.4
Kang, S.A.5
Spooner, E.6
Carr, S.A.7
Sabatini, D.M.8
-
13
-
-
33847397874
-
Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40
-
Vander Haar E., Lee S.I., Bandhakavi S., Griffin T.J., and Kim D.H. Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40. Nat Cell Biol. 9 (2007) 316-323
-
(2007)
Nat Cell Biol.
, vol.9
, pp. 316-323
-
-
Vander Haar, E.1
Lee, S.I.2
Bandhakavi, S.3
Griffin, T.J.4
Kim, D.H.5
-
14
-
-
67349217986
-
Molecular mechanisms of mTOR-mediated translational control
-
Ma X.M., and Blenis J. Molecular mechanisms of mTOR-mediated translational control. Nat Rev Mol Cell Biol. 10 (2009) 307-318
-
(2009)
Nat Rev Mol Cell Biol.
, vol.10
, pp. 307-318
-
-
Ma, X.M.1
Blenis, J.2
-
15
-
-
0032834055
-
eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation
-
Gingras A.C., Raught B., and Sonenberg N. eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annu Rev Biochem. 68 (1999) 913-963
-
(1999)
Annu Rev Biochem.
, vol.68
, pp. 913-963
-
-
Gingras, A.C.1
Raught, B.2
Sonenberg, N.3
-
16
-
-
0026318158
-
Establishment of bovine mammary epithelial cells (MAC-T): an in vitro model for bovine lactation
-
Huynh H.T., Robitaille G., and Turner J.D. Establishment of bovine mammary epithelial cells (MAC-T): an in vitro model for bovine lactation. Exp Cell Res. 197 (1991) 191-199
-
(1991)
Exp Cell Res.
, vol.197
, pp. 191-199
-
-
Huynh, H.T.1
Robitaille, G.2
Turner, J.D.3
-
17
-
-
0037178786
-
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
Kim D.H., Sarbassov D.D., Ali S.M., King J.E., Latek R.R., Erdjument-Bromage H., Tempst P., and Sabatini D.M. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell. 110 (2002) 163-175
-
(2002)
Cell.
, vol.110
, pp. 163-175
-
-
Kim, D.H.1
Sarbassov, D.D.2
Ali, S.M.3
King, J.E.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
18
-
-
0030716488
-
Regulation of eIF-4E BP1 Phosphorylation by mTOR
-
Hara K., Yonezawa K., Kozlowski M.T., Sugimoto T., Andrabi K., Weng Q.P., Kasuga M., Nishimoto I., and Avruch J. Regulation of eIF-4E BP1 Phosphorylation by mTOR. J Biol Chem. 272 (1997) 26457-26463
-
(1997)
J Biol Chem.
, vol.272
, pp. 26457-26463
-
-
Hara, K.1
Yonezawa, K.2
Kozlowski, M.T.3
Sugimoto, T.4
Andrabi, K.5
Weng, Q.P.6
Kasuga, M.7
Nishimoto, I.8
Avruch, J.9
-
19
-
-
0032539664
-
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1
-
Burnett P.E., Barrow R.K., Cohen N.A., Snyder S.H., and Sabatini D.M. RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. Proc Natl Acad Sci U S A. 95 (1998) 1432-1437
-
(1998)
Proc Natl Acad Sci U S A.
, vol.95
, pp. 1432-1437
-
-
Burnett, P.E.1
Barrow, R.K.2
Cohen, N.A.3
Snyder, S.H.4
Sabatini, D.M.5
-
20
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi D.R., Andjelkovic M., Caudwell B., Cron P., Morrice N., Cohen P., and Hemmings B.A. Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 15 (1996) 6541-6551
-
(1996)
EMBO J.
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
Hemmings, B.A.7
-
21
-
-
67651163607
-
Initiation and elongation steps of mRNA translation are involved in the increase in milk protein yield caused by growth hormone administration during lactation
-
Hayashi A.A., Nones K., Roy N.C., McNabb W.C., Mackenzie D.S., Pacheco D., and McCoard S. Initiation and elongation steps of mRNA translation are involved in the increase in milk protein yield caused by growth hormone administration during lactation. J Dairy Sci. 92 (2009) 1889-1899
-
(2009)
J Dairy Sci.
, vol.92
, pp. 1889-1899
-
-
Hayashi, A.A.1
Nones, K.2
Roy, N.C.3
McNabb, W.C.4
Mackenzie, D.S.5
Pacheco, D.6
McCoard, S.7
-
22
-
-
0025116696
-
Insulin-like growth factor-I concentration in Holstein female cattle: variations with age, stage of lactation and growth hormone-releasing factor administration
-
Abribat T., Lapierre H., Dubreuil P., Pelletier G., Gaudreau P., Brazeau P., and Petitclerc D. Insulin-like growth factor-I concentration in Holstein female cattle: variations with age, stage of lactation and growth hormone-releasing factor administration. Domest Anim Endocrinol. 7 (1990) 93-102
-
(1990)
Domest Anim Endocrinol.
, vol.7
, pp. 93-102
-
-
Abribat, T.1
Lapierre, H.2
Dubreuil, P.3
Pelletier, G.4
Gaudreau, P.5
Brazeau, P.6
Petitclerc, D.7
-
23
-
-
0029166687
-
The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins
-
Mader S., Lee H., Pause A., and Sonenberg N. The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins. Mol Cell Biol. 15 (1995) 4990-4997
-
(1995)
Mol Cell Biol.
, vol.15
, pp. 4990-4997
-
-
Mader, S.1
Lee, H.2
Pause, A.3
Sonenberg, N.4
-
24
-
-
57649112017
-
EGF, and sex steroids regulate autophagy in bovine mammary epithelial cells via the mTOR pathway
-
Sobolewska A., Gajewska M., Zarzyńska J., Gajkowska B., Motyl T., and IGF-1. EGF, and sex steroids regulate autophagy in bovine mammary epithelial cells via the mTOR pathway. Eur J Cell Biol. 88 (2009) 117-130
-
(2009)
Eur J Cell Biol.
, vol.88
, pp. 117-130
-
-
Sobolewska, A.1
Gajewska, M.2
Zarzyńska, J.3
Gajkowska, B.4
Motyl, T.5
IGF-16
-
25
-
-
17844369428
-
The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination
-
Benvenuto G., Li S., Brown S.J., Braverman R., Vass W.C., Cheadle J.P., Halley D.J., Sampson J.R., Wienecke R., and DeClue J.E. The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination. Oncogene. 19 (2000) 6306-6316
-
(2000)
Oncogene.
, vol.19
, pp. 6306-6316
-
-
Benvenuto, G.1
Li, S.2
Brown, S.J.3
Braverman, R.4
Vass, W.C.5
Cheadle, J.P.6
Halley, D.J.7
Sampson, J.R.8
Wienecke, R.9
DeClue, J.E.10
-
26
-
-
18544375193
-
Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin
-
Dan H.C., Sun M., Yang L., Feldman R.I., Sui X.M., Ou C.C., Nellist M., Yeung R.S., Halley D.J., Nicosia S.V., Pledger W.J., and Cheng J.Q. Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin. J Biol Chem. 277 (2002) 35364-35370
-
(2002)
J Biol Chem.
, vol.277
, pp. 35364-35370
-
-
Dan, H.C.1
Sun, M.2
Yang, L.3
Feldman, R.I.4
Sui, X.M.5
Ou, C.C.6
Nellist, M.7
Yeung, R.S.8
Halley, D.J.9
Nicosia, S.V.10
Pledger, W.J.11
Cheng, J.Q.12
-
27
-
-
34547133519
-
The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1
-
Oshiro N., Takahashi R., Yoshino K., Tanimura K., Nakashima A., Eguchi S., Miyamoto T., Hara K., Takehana K., Avruch J., Kikkawa U., and Yonezawa K. The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1. J Biol Chem. 282 (2007) 20329-20339
-
(2007)
J Biol Chem.
, vol.282
, pp. 20329-20339
-
-
Oshiro, N.1
Takahashi, R.2
Yoshino, K.3
Tanimura, K.4
Nakashima, A.5
Eguchi, S.6
Miyamoto, T.7
Hara, K.8
Takehana, K.9
Avruch, J.10
Kikkawa, U.11
Yonezawa, K.12
-
28
-
-
34547099855
-
PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding
-
Wang L., Harris T.E., Roth R.A., and Lawrence Jr. J.C. PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding. J Biol Chem. 282 (2007) 20036-20044
-
(2007)
J Biol Chem.
, vol.282
, pp. 20036-20044
-
-
Wang, L.1
Harris, T.E.2
Roth, R.A.3
Lawrence Jr., J.C.4
-
29
-
-
0037178781
-
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
-
Hara K., Maruki Y., Long X., Yoshino K., Oshiro N., Hidayat S., Tokunaga C., Avruch J., and Yonezawa K. Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action. Cell 110 (2002) 177-189
-
(2002)
Cell
, vol.110
, pp. 177-189
-
-
Hara, K.1
Maruki, Y.2
Long, X.3
Yoshino, K.4
Oshiro, N.5
Hidayat, S.6
Tokunaga, C.7
Avruch, J.8
Yonezawa, K.9
-
30
-
-
0038482156
-
Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor
-
Choi K.M., McMahon L.P., and Lawrence Jr. J.C. Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor. J Biol Chem. 278 (2003) 19667-19673
-
(2003)
J Biol Chem.
, vol.278
, pp. 19667-19673
-
-
Choi, K.M.1
McMahon, L.P.2
Lawrence Jr., J.C.3
-
31
-
-
0037507252
-
The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif
-
Nojima H., Tokunaga C., Eguchi S., Oshiro N., Hidayat S., Yoshino K., Hara K., Tanaka N., Avruch J., and Yonezawa K. The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif. J Biol Chem. 278 (2003) 15461-15464
-
(2003)
J Biol Chem.
, vol.278
, pp. 15461-15464
-
-
Nojima, H.1
Tokunaga, C.2
Eguchi, S.3
Oshiro, N.4
Hidayat, S.5
Yoshino, K.6
Hara, K.7
Tanaka, N.8
Avruch, J.9
Yonezawa, K.10
-
32
-
-
0037718389
-
TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function
-
Schalm S.S., Fingar D.C., Sabatini D.M., and Blenis J. TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function. Curr Biol. 13 (2003) 797-806
-
(2003)
Curr Biol.
, vol.13
, pp. 797-806
-
-
Schalm, S.S.1
Fingar, D.C.2
Sabatini, D.M.3
Blenis, J.4
-
33
-
-
47049127002
-
Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation
-
Wang L., Harris T.E., and Lawrence Jr. J.C. Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation. J Biol Chem. 283 (2008) 15619-15627
-
(2008)
J Biol Chem.
, vol.283
, pp. 15619-15627
-
-
Wang, L.1
Harris, T.E.2
Lawrence Jr., J.C.3
|