Bisdemethylcurcumin and structurally related hispolon analogues of curcumin exhibit enhanced prooxidant, anti-proliferative and anti-inflammatory activities in vitro

Biochemical Pharmacology

Volumn 79, Issue 11, 2010, Pages 1658-1666

  Ravindran, Jayaraj ^a,c   Subbaraju, Gottumukkala V ^b   Ramani, Modukuri V ^b   Sung, Bokyung ^a   Aggarwal, Bharat B ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b Aptuit Laurus Private Limited   (India)

^c Div of Pharmacology and Toxicology   (India)

Author keywords

Anti proliferation; Curcumin; Hispolon; NF B; TNF

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; BISDEMETHYLCURCUMIN; CURCUMIN; DEHYDROXY HISPOLON; HISPOLON; HISPOLON METHYL ETHER; HYDROXY HISPOLON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METHOXY HISPOLON; METHOXY HISPOLON METHYL ETHER; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME REPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; CATECHOLS; CELL LINE, TUMOR; CELL PROLIFERATION; CURCUMIN; HUMANS; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77950083774     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.01.033     Document Type: Article

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