Water-soluble polymer-drug conjugates for combination chemotherapy against visceral leishmaniasis

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 7, 2010, Pages 2559-2565

  Nicoletti, Salvatore ^a   Seifert, Karin ^b   Gilbert, Ian H ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Alendronate; Amphotericin B; Combination therapy; Leishmaniasis; Polymer drug conjugates

Indexed keywords

ALENDRONIC ACID; AMPHOTERICIN B; AMPHOTERICIN B DEOXYCHOLATE; AMPHOTERICIN B LIPID COMPLEX; N (2 HYDROXYPROPYL)METHACRYLAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG CONJUGATION; DRUG EFFICACY; DRUG SYNTHESIS; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; VISCERAL LEISHMANIASIS;

ANIMALS; ANTIPROTOZOAL AGENTS; BIOLOGICAL AVAILABILITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; FEMALE; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; LIVER; MACROPHAGES, PERITONEAL; MESOCRICETUS; METHACRYLATES; MICE; MICE, INBRED BALB C; POLYMERS; SOLUBILITY; SPECTROPHOTOMETRY, ULTRAVIOLET; WATER;

EID: 77950057958     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.02.043     Document Type: Article

References (33)

1. Chappuis F., Sundar S., Hailu A., Ghalib H., Rijal S., Peeling R.W., Alvar J., and Boelaert M. Nat. Rev. Microbiol. 5 (2007) 873
2. Alvar J., Croft S., and Olliaro P. Adv. Parasitol. 61 (2006) 223
3. Croft S.L., Sundar S., and Fairlamb A.H. Clin. Microbiol. Rev. 19 (2006) 111
4. Sundar S., Rai M., Chakravarty J., Agarwal D., Agrawal N., Vaillant M., Olliaro P., and Murray H.W. Clin. Infect. Dis. 47 (2008) 1000
5. Seifert K., and Croft S.L. Antimicrob. Agents Chemother. 50 (2006) 73
6. Duncan R. Nat. Rev. Drug Disc. 2 (2003) 347
7. Burchmore R.J.S., and Barrett M.P. Int. J. Parasitol. 31 (2001) 1311
8. Duncan R. Nat. Rev. Cancer 6 (2006) 688
9. Nan A., Croft S.L., Yardley V., and Ghandehari H. J. Controlled Release 94 (2004) 115
10. Nan A., Dhammika N.P., Walker L.A., Yardley V., Croft S.L., and Ghandehari H. J. Controlled Release 77 (2001) 233
11. Nicoletti S., Seifert K., and Gilbert I.H. Int. J. Antimicrob. Agents 33 (2009) 441
12. Vicent M.J., Greco F., Nicholson R.I., Paul A., Griffiths P.C., and Duncan R. Angew. Chem., Int. Ed. 44 (2005) 4061
13. Martin M.B., Grimley J.S., Lewis J.C., Heath III H.T., Bailey B.N., Kendrick H., Yardley V., Caldera A., Lira R., Urbina J.A., Moreno S.N., Docampo R., Croft S.L., and Oldfield E. J. Med. Chem. 44 (2001) 909
14. Ward L.M., Denker A.E., Porras A., Shugarts S., Kline W., Travers R., Mao C., Rauch F., Maes A., Larson P., Deutsch P., and Glorieux F.H. J. Clin. Endocrinol. Metab. 90 (2005) 4051
15. Kieczykowski G.R., Jobson R.B., Melillo D.G., Reinhold D.F., Grenda V.J., and Shinkai I. J. Org. Chem. 60 (1995) 8310
16. Chunge C.N., Owate J., Pamba H.O., and Donno L. Trans. R. Soc. Trop. Med. Hyg. 84 (1990) 221
17. Seaman J., Pryce D., Sondorp H.E., Moody A., Bryceson A.D., and Davidson R.N. J. Infect. Dis. 168 (1993) 715
18. Thakur C.P., Kanyok T.P., Pandey A.K., Sinha G.P., Messick C., and Olliaro P. Trans. R. Soc. Trop. Med. Hyg. 94 (2000) 432
19. Melaku Y., Collin S.M., Keus K., Gatluak F., Ritmeijer K., and Davidson R.N. Am. J. Trop. Med. Hyg. 77 (2007) 89
20. Sundar S., Mondal D., Rijal S., Bhattacharya S., Ghalib H., Kroeger A., Boelaert M., Desjeux P., Richter-Airijoki H., and Harms G. Trop. Med. Int. Health 13 (2008) 2
21. Kremsner P.G., and Krishna S. Lancet 364 (2004) 285
22. de Pilla Varotti F., Botelho A.C., Andrade A.A., de Paula R.C., Fagundes E.M., Valverde A., Mayer L.M., Mendonca J.S., de Souza M.V., Boechat N., and Krettli A.U. Antimicrob. Agents Chemother. (2008)
23. Sundar S., More D.K., Singh M.K., Singh V.P., Sharma S., Makharia A., Kumar P.C., and Murray H.W. Clin. Infect. Dis. 31 (2000) 1104
24. Brajtburg J., and Bolard J. Clin. Microbiol. Rev. 9 (1996) 512
25. van Beek E., Pieterman E., Cohen L., Lowik C., and Papapoulos S. Biochem. Biophys. Res. Commun. 264 (1999) 108
26. Rodriguez N., Bailey B.N., Martin M.B., Oldfield E., Urbina J.A., and Docampo R. J. Infect. Dis. 186 (2002) 138
27. Yardley V., Khan A.A., Martin M.B., Slifer T.R., Araujo F.G., Moreno S.N., Docampo R., Croft S.L., and Oldfield E. Antimicrob. Agents Chemother. 46 (2002) 929
28. Cremers S., van Hogezand R., Banffer D., Hartigh J., Vermeij P., Papapoulos S.E., and Hamdy N.A.T. Osteoporos. Int. 16 (2005) 1727
29. Papapoulos S.E. Best Pract. Res. Clin. Endocrinol. Metab. 22 (2008) 831
30. Wang D., Miller S., Sima M., Kopeckova P., and Kopecek J. Bioconjugate Chem. 14 (2003) 853
31. Miller K., Erez R., Segal E., Shabat D., and Satchi-Fainaro R. Angew. Chem., Int. Ed. 48 (2009) 2949
32. Vicent M.J., Greco F., Nicholson R.I., Paul A., Griffiths P.C., and Duncan R. Angew. Chem., Int. Ed. 44 (2005) 4061
33. Bradley D.J., and Kirkley J. Clin. Exp. Immunol. 30 (1977) 119