Treatment of visceral leishmaniasis with injectable paromomycin (aminosidine). An open-label randomized phase-II clinical study

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 94, Issue 4, 2000, Pages 432-433

  Thakur, C P ^a   Kanyok, T P ^b   Pandey, A K ^a   Sinha, G P ^a   Messick, C ^b   Olliaro, P ^b  

^a Kala azar Research Centre   (India)

^b WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

Chemotherapy; Clinical trial; India; Paromomycin; Sodium stibogluconate; Visceral leishmaniasis

Indexed keywords

ANTIMONY; PAROMOMYCIN; STIBOGLUCONATE SODIUM;

ADOLESCENT; ADULT; AMASTIGOTE; ARTICLE; AUDIOGRAPHY; BONE MARROW BIOPSY; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; FOLLOW UP; HUMAN; INJECTION; LEISHMANIA; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; NEPHROTOXICITY; OTOTOXICITY; PHASE 2 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; RELAPSE; SPLEEN; TREATMENT OUTCOME; VISCERAL LEISHMANIASIS;

LEISHMANIA MAJOR;

EID: 0033843320     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0035-9203(00)90131-7     Document Type: Article

References (7)

1. Treatment of visceral leishmaniasis in Kenya by aminosidine alone or combined with sodium stibogluconate
2. New breakthrough in treatment of visceral leishmaniasis in children
3. Randomised controlled trial of aminosidine (paromomycin) v sodium stibogluconate for treating visceral leishmaniasis in North Bihar, India
4. Epidemic visceral leishmaniasis in Sudan: A randomised trial of aminosidine plus sodium stibogluconate versus sodium stibogluconate alone
5. Aminosidine (paromomycin) in the treatment of leishmaniasis imported into the United Kingdom
6. Treatment of visceral leishmaniasis (kala-azar) with aminosidine (=paromomycin)-antimonial compounds, a pilot study in Bihar, India
7. Aminosidine plus sodium stibogluconate for the treatment of Indian kala-azar: A randomized dose-finding clinical trial