Isolation and characterization of stem cells derived from human third molar tooth germs of young adults: Implications in neo-vascularization, osteo-, adipo-and neurogenesis

Pharmacogenomics Journal

Volumn 10, Issue 2, 2010, Pages 105-113

  Yalvac, M E ^a   Ramazanoglu, M ^b   Rizvanov, A A ^a,c,d   Sahin, F ^a   Bayrak, O F ^a   Salli, U ^e   Palotas A ^f   Kose, G T ^a  

^a YEDITEPE UNIVERSITY   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

^c KAZAN FEDERAL UNIVERSITY   (Russian Federation)

^d KAZAN STATE MEDICAL UNIVERSITY   (Russian Federation)

^e PENN STATE COLLEGE OF MEDICINE   (United States)

^f Asklepios Med Bt   (Hungary)

Author keywords

Germ; Molar; Stem cell; Tooth; Transcription factor

Indexed keywords

5' NUCLEOTIDASE; ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; CD133 ANTIGEN; CD34 ANTIGEN; CD45 ANTIGEN; ENDOGLIN; KRUPPEL LIKE FACTOR 4; MATRIGEL; MESSENGER RNA; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; THY 1 ANTIGEN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2;

ADIPOGENESIS; ADOLESCENT; ANGIOGENESIS; ARTICLE; ASSAY; AUTOTRANSPLANTATION; BLOOD VESSEL; BONE DEVELOPMENT; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CHILD; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; MOLAR TOOTH; MULTIPOTENT STEM CELL; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NORMAL HUMAN; NUCLEAR REPROGRAMMING; NUCLEOTIDE SEQUENCE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SCHOOL CHILD; SOMATIC CELL; STEM CELL; TISSUE TYPES; TOOTH GERM STEM CELL;

ADIPOGENESIS; ADOLESCENT; CELL DIFFERENTIATION; CELL LINE; CELL SEPARATION; HOMEODOMAIN PROTEINS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MOLAR, THIRD; MULTIPOTENT STEM CELLS; NEUROGENESIS; OCTAMER TRANSCRIPTION FACTOR-3; OSTEOGENESIS; PROTO-ONCOGENE PROTEINS C-MYC; SOXB1 TRANSCRIPTION FACTORS; TOOTH GERM;

EID: 77950020375     PISSN: 1470269X     EISSN: 14731150     Source Type: Journal    
DOI: 10.1038/tpj.2009.40     Document Type: Article

References (44)

1. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999; 284: 143-147.
2. Jones EA, Kinsey SE, English A, Jones RA, Straszynski L, Meredith DM et al. Isolation and characterization of bone marrow multipotential mesenchymal progenitor cells. Arthritis Rheum 2002; 46: 3349-3360.
3. Ferrari G, Cusella-De Angelis G, Coletta M, Paolucci E, Stornaiuolo A, Cossu G et al. Muscle regeneration by bone marrow-derived myogenic progenitors. Science 1998; 279: 1528-1530.
4. Ianus A, Holz GG, Theise ND, Hussain MA. In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion. J Clin Invest 2003; 111: 843-850.
5. Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418: 41-49.
6. Mezey E, Key S, Vogelsang G, Szalayova I, Lange GD, Crain B. Transplanted bone marrow generates new neurons in human brains. Proc Natl Acad Sci USA 2003; 100: 1364-1369.
7. Petersen BE, Bowen WC, Patrene KD, Mars WM, Sullivan AK, Murase N et al. Bone marrow as a potential source of hepatic oval cells. Science 1999; 284: 1168-1170.
8. Campagnoli C, Roberts IA, Kumar S, Bennett PR, Bellantuono I, Fisk NM. Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow. Blood 2001; 98: 2396-2402.
9. De Bari C, Dell'Accio F, Tylzanowski P, Luyten FP. Multipotent mesenchymal stem cells from adult human synovial membrane. Arthritis Rheum 2001; 44: 1928-1942.
10. Salingcarnboriboon R, Yoshitake H, Tsuji K, Obinata M, Amagasa T, Nifuji A et al. Establishment of tendon-derived cell lines exhibiting pluripotent mesenchymal stem cell-like property. Exp Cell Res 2003; 287: 289-300.
11. Toma JG, McKenzie IA, Bagli D, Miller FD. Isolation and characterization of multipotent skin-derived precursors from human skin. Stem Cells 2005; 23: 727-737.
12. Zuk PA, Zhu M, Ashjian P, De Ugarte DA, Huang JI, Mizuno H et al. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 2002; 13: 4279-4295.
13. Graziano A, d'Aquino R, Laino G, Papaccio G. Dental pulp stem cells: a promising tool for bone regeneration. Stem Cell Rev 2008; 4: 21-26.
14. Bosshardt DD. Are cementoblasts a subpopulation of osteoblasts or a unique phenotype? J Dent Res 2005; 84: 390-406.
15. Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Natl Acad Sci USA 2000; 97: 13625-13630.
16. Miura M, Gronthos S, Zhao M, Lu B, Fisher LW, Robey PG et al. SHED: stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci USA 2003; 100: 5807-5812.
17. Seo BM, Miura M, Gronthos S, Bartold PM, Batouli S, Brahim J et al. Investigation of multipotent postnatal stem cells from human period-ontal ligament. Lancet 2004; 364: 149-155.
18. Ikeda E, Hirose M, Kotobuki N, Shimaoka H, Tadokoro M, Maeda M et al. Osteogenic differentiation of human dental papilla mesenchymal cells. Biochem Biophys Res Commun 2006; 342: 1257-1262.
19. Yao S, Norton J, Wise GE. Stability of cultured dental follicle cells. Cell Prolif 2004; 37: 247-254.
20. Morsczeck C, Gotz W, Schierholz J, Zeilhofer F, Kuhn U, Mohl C et al. Isolation of precursor cells (PCs) from human dental follicle of wisdom teeth. Matrix Biol 2005; 24: 155-165.
21. Ten Cate AR, Mills C. The development of the periodontium: the origin of alveolar bone. Anat Rec 1972; 173: 69-77.
22. Park BW, Hah YS, Kim DR, Kim JR, Byun JH. Osteogenic phenotypes and mineralization of cultured human periosteal-derived cells. Arch Oral Biol 2007; 52: 983-989.
23. Lindroos B, Maenpaa K, Ylikomi T, Oja H, Suuronen R, Miettinen S. Characterisation of human dental stem cells and buccal mucosa fibroblasts. Biochem Biophys Res Commun 2008; 368: 329-335.
24. Yalvac ME, Ramazanoglu M, Gumru OZ, Sahin F, Palotas A, Rizvanov AA. Comparison and optimisation of transfection of human dental follicle cells, a novel source of stem cells, with different chemical methods and electro-poration. Neurochem Res 2009; 34: 1272-1277.
25. Iohara K, Zheng L, Ito M, Tomokiyo A, Matsushita K, Nakashima M. Side population cells isolated from porcine dental pulp tissue with self-renewal and multipotency for dentinogenesis, chondrogen-esis, adipogenesis, and neurogenesis. Stem Cells 2006; 24: 2493-2503.
26. Jo YY, Lee HJ, Kook SY, Choung HW, Park JY, Chung JH et al. Isolation and characterization of postnatal stem cells from human dental tissues. Tissue Eng 2007; 13: 767-773.
27. Ikeda E, Yagi K, Kojima M, Yagyuu T, Ohshima A, Sobajima S et al. Multipotent cells from the human third molar: feasibility of cell-based therapy for liver disease. Differentiation 2008; 76: 495-505.
28. Takeda T, Tezuka Y, Horiuchi M, Hosono K, Iida K, Hatakeyama D et al. Characterization of dental pulp stem cells of human tooth germs. J Dent Res 2008; 87: 676-681.
29. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-676.
30. Park IH, Zhao R, West JA, Yabuuchi A, Huo H, Ince TA et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 2008; 451: 141-146.
31. Kim JB, Zaehres H, Wu G, Gentile L, Ko K, Sebastiano V et al. Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature 2008; 454: 646-650.
32. Lagarkova MA, Volchkov PY, Lyakisheva AV, Philonenko ES, Kiselev SL. Diverse epigenetic profile of novel human embryonic stem cell lines. Cell Cycle 2006; 5: 416-420.
33. Gage FH. Mammalian neural stem cells. Science 2000; 287: 1433-1438.
34. Kafienah W, Mistry S, Williams C, Hollander AP. Nucleostemin is a marker of proliferating stromal stem cells in adult human bone marrow. Stem Cells 2006; 24: 1113-1120.
35. Pesce M, Anastassiadis K, Scholer HR. Oct-4: lessons of totipotency from embryonic stem cells. Cells Tissues Organs 1999; 165: 144-152.
36. Reyes M, Dudek A, Jahagirdar B, Koodie L, Marker PH, Verfaillie CM. Origin of endothelial progenitors in human postnatal bone marrow. J Clin Invest 2002; 109: 337-346.
37. Annabi B, Lee YT, Turcotte S, Naud E, Desrosiers RR, Champagne M et al. Hypoxia promotes murine bone-marrow-derived stromal cell migration and tube formation. Stem Cells 2003; 21: 337-347.
38. McLaughlin D, Tsirimonaki E, Vallianatos G, Sakellaridis N, Chatzistamatiou T, Stavropoulos-Gioka C et al. Stable expression of a neuronal dopaminergic progenitor phenotype in cell lines derived from human amniotic fluid cells. J Neurosci Res 2006; 83: 1190-1200.
39. Xiao ZS, Quarles LD, Chen QQ, Yu YH, Qu XP, Jiang CH et al. Effect of asymmetric dimethylarginine on osteoblastic differentiation. Kidney Int 2001; 60: 1699-1704.
40. Yoon SY, Park KS, Choi BS, Khang G, Kim MS, Rhee JM et al. Effect of DBP/PLGA hybrid scaffold on angiogenesis during the repair of calvarial bone defect. Key Eng Mater 2007; 342-343: 161-164.
41. Somogyi R, Wen X, Ma W, Barker JL. Developmental kinetics of GAD family mRNAs parallel neurogenesis in the rat spinal cord. J Neurosci 1995; 15: 2575-2591.
42. Saji M, Xydas S, Westra WH, Liang CK, Clark DP, Udelsman R et al. Human telomerase reverse transcriptase (hTERT) gene expression in thyroid neoplasms. Clin Cancer Res 1999; 5: 1483-1489.
43. Tare RS, Howard D, Pound JC, Roach HI, Oreffo RC. Tissue engineering strategies for cartilage generation micromass and three dimensional cultures using human chondrocytes and a continuous cell line. Biochem Biophys Res Commun 2005; 333: 609-621.
44. Kameda Y, Arai Y, Nishimaki T. Ultrastructural localization of vimentin immunoreactivity and gene expression in tanycytes and their alterations in hamsters kept under different photoperiods. Cell Tissue Res 2003; 314: 251-262.