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Volumn 165, Issue 3-4, 1999, Pages 144-152

Oct-4: Lessons of totipotency from embryonic stem cells

Author keywords

Embryonic stem cell; Germ cell; Oct 4; Transcription factor

Indexed keywords

OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 0032731129     PISSN: 14226405     EISSN: None     Source Type: Journal    
DOI: 10.1159/000016694     Document Type: Article
Times cited : (92)

References (40)
  • 1
    • 0030820931 scopus 로고
    • Synergistic activation of the fibroblast growth factor 4 enhancer by Sox-2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding site
    • Ambrosetti, D.-C., C. Basilico, L. Dailey (1977) Synergistic activation of the fibroblast growth factor 4 enhancer by Sox-2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding site. Mol Cell Biol 17: 6321-6329.
    • (1977) Mol Cell Biol , vol.17 , pp. 6321-6329
    • Ambrosetti, D.-C.1    Basilico, C.2    Dailey, L.3
  • 2
    • 0031306926 scopus 로고    scopus 로고
    • Oocyte influences on early development: The regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation stage embryo
    • Antczak, M., J. Van Blerkom (1997) Oocyte influences on early development: The regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation stage embryo. Mol Hum Reprod 3, 1067-1086.
    • (1997) Mol Hum Reprod , vol.3 , pp. 1067-1086
    • Antczak, M.1    Van Blerkom, J.2
  • 3
    • 0027518346 scopus 로고
    • Extinction of Oct-3/4 gene expression in embryonal carcinoma × fibroblast somatic cell hybrids is accompanied by changes in the methylation status, chromatin structure and transcriptional activity of the Oct-3/4 upstream region
    • Ben-Shushan, E., E. Pikarsky, A. Klar, Y. Bergman (1993) Extinction of Oct-3/4 gene expression in embryonal carcinoma × fibroblast somatic cell hybrids is accompanied by changes in the methylation status, chromatin structure and transcriptional activity of the Oct-3/4 upstream region. Mol Cell Biol 13: 891-901.
    • (1993) Mol Cell Biol , vol.13 , pp. 891-901
    • Ben-Shushan, E.1    Pikarsky, E.2    Klar, A.3    Bergman, Y.4
  • 4
    • 0031949215 scopus 로고    scopus 로고
    • Rex-1, a gene encoding a transcription factor expressed in the early embryo, is regulated via Oct-3/4 and Oct-6 binding to an octamcr site and a novel protein, Rox-1, binding to an adjacent site
    • Ben-Sushan, E., J.R. Thompson, L.J. Gudas, Y. Berman (1998) Rex-1, a gene encoding a transcription factor expressed in the early embryo, is regulated via Oct-3/4 and Oct-6 binding to an octamcr site and a novel protein, Rox-1, binding to an adjacent site. Mol Cell Biol 18. 1866-1878.
    • (1998) Mol Cell Biol , vol.18 , pp. 1866-1878
    • Ben-Sushan, E.1    Thompson, J.R.2    Gudas, L.J.3    Berman, Y.4
  • 5
    • 0032128171 scopus 로고    scopus 로고
    • New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2
    • Botquin, V., H. Hess, G. Fuhrmann, K. Anastassiadis, M.K. Gross, G. Vriend, H.R. Schöler (1998) New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2. Genes Dev 12: 2073-2090.
    • (1998) Genes Dev , vol.12 , pp. 2073-2090
    • Botquin, V.1    Hess, H.2    Fuhrmann, G.3    Anastassiadis, K.4    Gross, M.K.5    Vriend, G.6    Schöler, H.R.7
  • 6
    • 0031014396 scopus 로고    scopus 로고
    • The carboxy-terminal transactivation domain of Oct-4 acquires cell specificity through the POU domain
    • Brehm, A., K. Ohbo, H.R. Schöler (1997) The carboxy-terminal transactivation domain of Oct-4 acquires cell specificity through the POU domain. Mol Cell Biol 17: 154-162.
    • (1997) Mol Cell Biol , vol.17 , pp. 154-162
    • Brehm, A.1    Ohbo, K.2    Schöler, H.R.3
  • 7
    • 0032940189 scopus 로고    scopus 로고
    • Syrergism with germ line transcription factor Oct-4: Viral oncoproteins share the ability to mimic a stem cell-specific activity
    • Brehm, A., K. Ohbo, W. Zwerschke, V. Botquin, P. Jansen-Dürr, H.R. Schöler (1999) Syrergism with germ line transcription factor Oct-4: Viral oncoproteins share the ability to mimic a stem cell-specific activity. Mol Cell Biol 19: 2635-2643.
    • (1999) Mol Cell Biol , vol.19 , pp. 2635-2643
    • Brehm, A.1    Ohbo, K.2    Zwerschke, W.3    Botquin, V.4    Jansen-Dürr, P.5    Schöler, H.R.6
  • 8
    • 0025368680 scopus 로고
    • Expression of the K-fgf proto-oncogene is controlled by 3′ regulatory elements which are specific for embryonal carcinoma cells
    • Curatola, A.M., C. Basilico (1990) Expression of the K-fgf proto-oncogene is controlled by 3′ regulatory elements which are specific for embryonal carcinoma cells. Mol Cell Biol 10: 2475-2484.
    • (1990) Mol Cell Biol , vol.10 , pp. 2475-2484
    • Curatola, A.M.1    Basilico, C.2
  • 9
    • 0028718860 scopus 로고
    • Evolutionary aspects of primordial germ cells formation
    • Marsh, J., J. Goode (eds): Chichester, Wiley
    • Dixon, K.E. (1994) Evolutionary aspects of primordial germ cells formation; in Marsh, J., J. Goode (eds): Germline Development. Chichester, Wiley, pp 92-120.
    • (1994) Germline Development , pp. 92-120
    • Dixon, K.E.1
  • 11
    • 0025147087 scopus 로고
    • Primordial germ cells in the mouse embryo during gastrulation
    • Ginsburg, M., M.H.L. Snow, A. McLaren (1990) Primordial germ cells in the mouse embryo during gastrulation. Development 110: 521-528.
    • (1990) Development , vol.110 , pp. 521-528
    • Ginsburg, M.1    Snow, M.H.L.2    McLaren, A.3
  • 12
    • 0017903760 scopus 로고
    • Temporal and spatial patterns of the synthesis of tissue-specific polypeptides in the preimplantation mouse embryo
    • Handyside, A.H., M.H. Johnson (1978) Temporal and spatial patterns of the synthesis of tissue-specific polypeptides in the preimplantation mouse embryo. J Embryol Exp Morphol 44: 191-199.
    • (1978) J Embryol Exp Morphol , vol.44 , pp. 191-199
    • Handyside, A.H.1    Johnson, M.H.2
  • 13
    • 0029124988 scopus 로고
    • The POU domain: Versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain
    • Herr, W., M.A. Cleary (1995) The POU domain: Versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain. Genes Dev 9: 1679-1693.
    • (1995) Genes Dev , vol.9 , pp. 1679-1693
    • Herr, W.1    Cleary, M.A.2
  • 14
    • 0027273372 scopus 로고
    • An octamer motif contributes to the expression of the retinoic acid-regulated zinc finger gene Rex-1 (Zfp-42) in F9 teratocarcinoma cells
    • Hosler, B., M.B. Rogers, C.A. Kozak, L.J. Gudas (1993) An octamer motif contributes to the expression of the retinoic acid-regulated zinc finger gene Rex-1 (Zfp-42) in F9 teratocarcinoma cells. Mol Cell Biol 13: 2919-2928.
    • (1993) Mol Cell Biol , vol.13 , pp. 2919-2928
    • Hosler, B.1    Rogers, M.B.2    Kozak, C.A.3    Gudas, L.J.4
  • 15
    • 0030743612 scopus 로고    scopus 로고
    • DNA methylation and imprinting: Why bother?
    • Jaenisch, R. (1997) DNA methylation and imprinting: Why bother? Trends Genet 13: 323-329.
    • (1997) Trends Genet , vol.13 , pp. 323-329
    • Jaenisch, R.1
  • 16
    • 0028724198 scopus 로고
    • Clonal analysis of the origin of primordial germ cells in the mouse
    • Marsh, J., J. Goode (eds): Chichester, Wiley
    • Lawson, K.A., W.J. Hage (1994) Clonal analysis of the origin of primordial germ cells in the mouse; in Marsh, J., J. Goode (eds): Germline Development. Chichester, Wiley, pp 68-91.
    • (1994) Germline Development , pp. 68-91
    • Lawson, K.A.1    Hage, W.J.2
  • 17
    • 0024543529 scopus 로고
    • Repression of the IgH enhancer in teratocarcinoma cells associated with a novel octamer factor
    • Lenardo, M.J., L. Staudt, P. Robbins, A. Kuang, R.C. Mulligan, D. Baltimore (1989) Repression of the IgH enhancer in teratocarcinoma cells associated with a novel octamer factor. Science 243: 544-546.
    • (1989) Science , vol.243 , pp. 544-546
    • Lenardo, M.J.1    Staudt, L.2    Robbins, P.3    Kuang, A.4    Mulligan, R.C.5    Baltimore, D.6
  • 18
    • 0030752573 scopus 로고    scopus 로고
    • Silencing of the gene for the α-subunit of human chorionic gonadotropin by the embryonic transcription factor Oct-3/4
    • Liu, L., D. Laeman, M. Villalta, R.M. Roberts (1997) Silencing of the gene for the α-subunit of human chorionic gonadotropin by the embryonic transcription factor Oct-3/4. Mol Endocrinol 11: 1651-1658.
    • (1997) Mol Endocrinol , vol.11 , pp. 1651-1658
    • Liu, L.1    Laeman, D.2    Villalta, M.3    Roberts, R.M.4
  • 19
    • 0030006923 scopus 로고    scopus 로고
    • Silencing of the gene for the β subunit of human chorionic gonadotropin by the embryonic transcription factor Oct-4
    • Liu, L., R.M. Roberts (1996) Silencing of the gene for the β subunit of human chorionic gonadotropin by the embryonic transcription factor Oct-4. J Biol Chem 271: 16683-16689.
    • (1996) J Biol Chem , vol.271 , pp. 16683-16689
    • Liu, L.1    Roberts, R.M.2
  • 20
    • 0030059509 scopus 로고    scopus 로고
    • Retinoic acid-mediated down-regulation of Oct 3/4 coincides with the loss of promoter occupancy in vivo
    • Minucci, S., V. Botquin, Y.I. Yeom, A. Dey, I. Sylvester, D. Zand, K. Ozato, H.R. Schöler (1996) Retinoic acid-mediated down-regulation of Oct 3/4 coincides with the loss of promoter occupancy in vivo. EMBO J 15: 888-899.
    • (1996) EMBO J , vol.15 , pp. 888-899
    • Minucci, S.1    Botquin, V.2    Yeom, Y.I.3    Dey, A.4    Sylvester, I.5    Zand, D.6    Ozato, K.7    Schöler, H.R.8
  • 21
    • 0023119242 scopus 로고
    • Temporal and spatial changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development
    • Monk, M., M. Boubelik, S. Lehnert (1987) Temporal and spatial changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development. Development 99: 371-382.
    • (1987) Development , vol.99 , pp. 371-382
    • Monk, M.1    Boubelik, M.2    Lehnert, S.3
  • 23
    • 0025812646 scopus 로고
    • The oct3 gene, a gene for a embryonic transcription factor, is controlled by a retinoic acid repressible enhancer
    • Okazawa, H., K. Okamoto, F. Ishino, T. Ishino-Kaneko, Y. Toyoda, M. Muramatsu, M.H. Hamada (1991) The oct3 gene, a gene for a embryonic transcription factor, is controlled by a retinoic acid repressible enhancer. EMBO J 10: 2997-3005.
    • (1991) EMBO J , vol.10 , pp. 2997-3005
    • Okazawa, H.1    Okamoto, K.2    Ishino, F.3    Ishino-Kaneko, T.4    Toyoda, Y.5    Muramatsu, M.6    Hamada, M.H.7
  • 24
    • 0027959928 scopus 로고
    • Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation
    • Palmieri, S., W. Peter, H. Hess, H.R. Schöler (1994) Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation. Dev Biol 166: 259-267.
    • (1994) Dev Biol , vol.166 , pp. 259-267
    • Palmieri, S.1    Peter, W.2    Hess, H.3    Schöler, H.R.4
  • 25
    • 0032170283 scopus 로고    scopus 로고
    • In line with our ancestors: Oct-4 and the mammalian germ
    • Pesce, M., M.K. Gross, H.R. Schöler (1998a) In line with our ancestors: Oct-4 and the mammalian germ. Bioessays 20: 722-732.
    • (1998) Bioessays , vol.20 , pp. 722-732
    • Pesce, M.1    Gross, M.K.2    Schöler, H.R.3
  • 26
    • 0032008045 scopus 로고    scopus 로고
    • Differential expression of the Oct-4 transcription factor during mouse germ cell differentiation
    • Pesce, M., X. Wang, D. Wolgemuth, H.R. Schöler (1998b) Differential expression of the Oct-4 transcription factor during mouse germ cell differentiation. Mech Dev 71: 89-98.
    • (1998) Mech Dev , vol.71 , pp. 89-98
    • Pesce, M.1    Wang, X.2    Wolgemuth, D.3    Schöler, H.R.4
  • 27
    • 0030918673 scopus 로고    scopus 로고
    • POU domain family values: Flexibility, partnerships, and developmental codes
    • Ryan, A.K., M.G. Rosenfel (1997) POU domain family values: Flexibility, partnerships, and developmental codes. Genes Dev 11: 1207-1225.
    • (1997) Genes Dev , vol.11 , pp. 1207-1225
    • Ryan, A.K.1    Rosenfel, M.G.2
  • 28
    • 0027527299 scopus 로고
    • Hybrid cell extinction and reexpression of Oct-3 function correlates with differentiation potential
    • Shimazaki, T., H. Okazawa, H. Fuji, M. Ikeda, K. Tamai, R.D.G. McKay, M. Muramatsu, H. Hamada (1993) Hybrid cell extinction and reexpression of Oct-3 function correlates with differentiation potential. EMBO J 12: 4489-4498.
    • (1993) EMBO J , vol.12 , pp. 4489-4498
    • Shimazaki, T.1    Okazawa, H.2    Fuji, H.3    Ikeda, M.4    Tamai, K.5    McKay, R.D.G.6    Muramatsu, M.7    Hamada, H.8
  • 29
    • 0024462072 scopus 로고
    • Octamer binding proteins confer transcriptional activity in early mouse embryogenesis
    • Schöler, H.R., R. Balling, A.K. Hatzopoulos, N. Suzuki, P. Gruss (1989) Octamer binding proteins confer transcriptional activity in early mouse embryogenesis. EMBO J 8: 2551-2557.
    • (1989) EMBO J , vol.8 , pp. 2551-2557
    • Schöler, H.R.1    Balling, R.2    Hatzopoulos, A.K.3    Suzuki, N.4    Gruss, P.5
  • 30
    • 0025744521 scopus 로고
    • A nexus between Oct-4 and E1A: Implication for gene regulation in embryonic stem cells
    • Schöler, H.R., T. Ciesiolka, P. Gruss (1991) A nexus between Oct-4 and E1A: Implication for gene regulation in embryonic stem cells. Cell 66: 291-304.
    • (1991) Cell , vol.66 , pp. 291-304
    • Schöler, H.R.1    Ciesiolka, T.2    Gruss, P.3
  • 31
    • 0025291459 scopus 로고
    • Oct-4: A germline-specific transcription factor mapping to the mouse t-complex
    • Schöler, H.R., G.R. Dressler, R. Balling, H. Rohdewold, P. Gruss (1990b) Oct-4: A germline-specific transcription factor mapping to the mouse t-complex. EMBO J 7: 2185-2195.
    • (1990) EMBO J , vol.7 , pp. 2185-2195
    • Schöler, H.R.1    Dressler, G.R.2    Balling, R.3    Rohdewold, H.4    Gruss, P.5
  • 32
    • 0025319004 scopus 로고
    • New type of POU domain in germ line-specific protein Oct-4
    • Schöler, H.R., S. Ruppert, N. Suzuki, K. Chowdhury, P. Gruss (1990a) New type of POU domain in germ line-specific protein Oct-4. Nature 344: 435-439.
    • (1990) Nature , vol.344 , pp. 435-439
    • Schöler, H.R.1    Ruppert, S.2    Suzuki, N.3    Chowdhury, K.4    Gruss, P.5
  • 33
    • 0032076565 scopus 로고    scopus 로고
    • Imprinting and the initiation of gene silencing in the germ line
    • Surani, M.A. (1998) Imprinting and the initiation of gene silencing in the germ line. Cell 93: 309-312.
    • (1998) Cell , vol.93 , pp. 309-312
    • Surani, M.A.1
  • 34
    • 23444450223 scopus 로고
    • Regulation of the Oct-4 gene by nuclear receptors
    • Sylvester, I., H.R. Schöler (1994) Regulation of the Oct-4 gene by nuclear receptors. Nucleic Acids Res 22: 901-911.
    • (1994) Nucleic Acids Res , vol.22 , pp. 901-911
    • Sylvester, I.1    Schöler, H.R.2
  • 35
    • 0026640910 scopus 로고
    • Human Oct-3 gene family: CDNA sequences, alternative splicing, gene organization, chromosomal localization, and expression at low levels in adult tissues
    • Takeda, J., S. Seino, G.I. Bell (1992) Human Oct-3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal localization, and expression at low levels in adult tissues. Nucleic Acids Res 20: 4613-4620.
    • (1992) Nucleic Acids Res , vol.20 , pp. 4613-4620
    • Takeda, J.1    Seino, S.2    Bell, G.I.3
  • 36
    • 0030601343 scopus 로고    scopus 로고
    • The allocation of epiblast cells to ectodermal and germ-line lineages is influenced by the position of the cells in the gastrulating mouse embryo
    • Tam, P.P.L., S.X. Zhou (1996) The allocation of epiblast cells to ectodermal and germ-line lineages is influenced by the position of the cells in the gastrulating mouse embryo. Dev Biol 178: 124-132.
    • (1996) Dev Biol , vol.178 , pp. 124-132
    • Tam, P.P.L.1    Zhou, S.X.2
  • 37
    • 0031573953 scopus 로고    scopus 로고
    • Inactivation of the FGF-4 gene in embryonic stem cells alters the growth and/or the survival of their early differentiated progeny
    • Wilder, P.J., D. Kelly, K. Brigman, C.L. Peterson, T. Nowling, Q.-S. Gao, R.D. McComb, M.R. Capecchi, A. Rizzino (1997) Inactivation of the FGF-4 gene in embryonic stem cells alters the growth and/or the survival of their early differentiated progeny. Dev Biol 192: 614-629.
    • (1997) Dev Biol , vol.192 , pp. 614-629
    • Wilder, P.J.1    Kelly, D.2    Brigman, K.3    Peterson, C.L.4    Nowling, T.5    Gao, Q.-S.6    McComb, R.D.7    Capecchi, M.R.8    Rizzino, A.9
  • 38
    • 0028808183 scopus 로고
    • Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox-2 and Oct-3
    • Yuan, H.N., N. Corbi, C. Basilico, L. Dailey (1995) Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox-2 and Oct-3. Genes Dev 9: 2635-2645.
    • (1995) Genes Dev , vol.9 , pp. 2635-2645
    • Yuan, H.N.1    Corbi, N.2    Basilico, C.3    Dailey, L.4
  • 40
    • 0025988092 scopus 로고
    • Structure, expression and chromosomal localization of the Oct-4 gene
    • Yeom, Y.I., H.-S. Ha, R. Balling, H.R. Schöler, K. Artzt (1991) Structure, expression and chromosomal localization of the Oct-4 gene. Mech Dev 35: 171-179.
    • (1991) Mech Dev , vol.35 , pp. 171-179
    • Yeom, Y.I.1    Ha, H.-S.2    Balling, R.3    Schöler, H.R.4    Artzt, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.