Activation of endothelial nitric oxide synthase by the pro-apoptotic drug embelin: Striking discrepancy between nitric oxide-mediated cyclic GMP accumulation and l-citrulline formation

Nitric Oxide - Biology and Chemistry

Volumn 22, Issue 4, 2010, Pages 281-289

  Schmidt, Kurt ^a   Martens Lobenhoffer, Jens ^b   Meinitzer, Andreas ^c   Graier, Wolfgang F ^c   Torres, Christina M ^d   Venema, Richard C ^d   Mayer, Bernd ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c MEDICAL UNIVERSITY OF GRAZ   (Austria)

^d MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

cGMP; Embelin; Endothelial nitric oxide synthase; l Citrulline; Nitric oxide; Soluble guanylate cyclase

Indexed keywords

ADENOSINE TRIPHOSPHATE; ARGININE; CALCIMYCIN; CALCIUM ION; CITRULLINE; CYCLIC GMP; EMBELIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GUANYLATE CYCLASE; NITRIC OXIDE; THAPSIGARGIN;

AMINO ACID METABOLISM; AMINO ACID TRANSPORT; ANIMAL CELL; APOPTOSIS; ARTICLE; BIOAVAILABILITY; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL CULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; FLUORESCENCE; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BENZOQUINONES; CITRULLINE; CYCLIC GMP; ENDOTHELIAL CELLS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; SIGNAL TRANSDUCTION;

EID: 77949915404     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.niox.2010.02.001     Document Type: Article

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