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Volumn 30, Issue 2, 2010, Pages 121-132

TACI induces cIAP1-mediated ubiquitination of NIK by TRAF2 and TANK to limit non-canonical NF-κB signaling

Author keywords

BAFF R; NF B2 p100; NIK; TACI; TANK

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; PROTEIN P100; SMALL INTERFERING RNA; TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2;

EID: 77949907794     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.3109/10799891003634509     Document Type: Article
Times cited : (11)

References (52)
  • 2
    • 0035860466 scopus 로고    scopus 로고
    • BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF
    • Thompson JS, Bixler SA, Qian F, et al. BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science 2001;293:2108-2111
    • (2001) Science , vol.293 , pp. 2108-2111
    • Thompson, J.S.1    Bixler, S.A.2    Qian, F.3
  • 3
    • 0034919939 scopus 로고    scopus 로고
    • Activation and accumulation of B cells in TACI-deficient mice
    • Yan M, Wang H, Chan B, et al. Activation and accumulation of B cells in TACI-deficient mice. Nat Immunol 2001;2:638-643
    • (2001) Nat Immunol , vol.2 , pp. 638-643
    • Yan, M.1    Wang, H.2    Chan, B.3
  • 4
    • 0035004320 scopus 로고    scopus 로고
    • Regulation of the T-independent humoral response by TACI
    • Von Bulow GU, Van Deursen JM, Bram RJ. Regulation of the T-independent humoral response by TACI. Immunity 2001;14:573-582
    • (2001) Immunity , vol.14 , pp. 573-582
    • Von Bulow, G.U.1    Van Deursen, J.M.2    Bram, R.J.3
  • 5
    • 0037332043 scopus 로고    scopus 로고
    • Loss of TACI causes fatal lymphoproliferation and autoImmunity, establishing TACI as an inhibitory BLyS receptor
    • Seshasayee D, Valdez P, Yan M, Dixit VM, Tumas D, Grewal IS. Loss of TACI causes fatal lymphoproliferation and autoImmunity, establishing TACI as an inhibitory BLyS receptor. Immunity 2003;18:279-288
    • (2003) Immunity , vol.18 , pp. 279-288
    • Seshasayee, D.1    Valdez, P.2    Yan, M.3    Dixit, V.M.4    Tumas, D.5    Grewal, I.S.6
  • 6
    • 33745193755 scopus 로고    scopus 로고
    • BAFF and APRIL as osteoclastderived survival factors for myeloma cells: A rationale for TACI-Fc treatment in patients with multiple myeloma
    • Abe M, Kido S, Hiasa M, et al. BAFF and APRIL as osteoclastderived survival factors for myeloma cells: a rationale for TACI-Fc treatment in patients with multiple myeloma. Leukemia 2006;20:1313-1315
    • (2006) Leukemia , vol.20 , pp. 1313-1315
    • Abe, M.1    Kido, S.2    Hiasa, M.3
  • 8
    • 33947592601 scopus 로고    scopus 로고
    • TACI regulates IgA production by APRIL in collaboration with HSPG
    • Sakurai D, Hase H, Kanno Y, Kojima H, Okumura K, Kobata T. TACI regulates IgA production by APRIL in collaboration with HSPG. Blood 2007;109:2961-2967
    • (2007) Blood , vol.109 , pp. 2961-2967
    • Sakurai, D.1    Hase, H.2    Kanno, Y.3    Kojima, H.4    Okumura, K.5    Kobata, T.6
  • 9
    • 33846351257 scopus 로고    scopus 로고
    • To switch or not to switch- the opposing roles of TACI in terminal B cell differentiation
    • Salzer U, Jennings S, Grimbacher B. To switch or not to switch- the opposing roles of TACI in terminal B cell differentiation. Eur J Immunol 2007;37:17-20.
    • (2007) Eur J Immunol , vol.37 , pp. 17-20
    • Salzer, U.1    Jennings, S.2    Grimbacher, B.3
  • 10
    • 0036794398 scopus 로고    scopus 로고
    • BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells
    • Claudio E, Brown K, Park S, Wang H, Siebenlist U. BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells. Nat Immunol 2002;3:958-965
    • (2002) Nat Immunol , vol.3 , pp. 958-965
    • Claudio, E.1    Brown, K.2    Park, S.3    Wang, H.4    Siebenlist, U.5
  • 11
    • 18644369740 scopus 로고    scopus 로고
    • BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2
    • Kayagaki N, Yan M, Seshasayee D, et al. BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2. Immunity 2002;17:515-524
    • (2002) Immunity , vol.17 , pp. 515-524
    • Kayagaki, N.1    Yan, M.2    Seshasayee, D.3
  • 12
    • 33845422163 scopus 로고    scopus 로고
    • Control of B lymphocyte apoptosis by the transcription factor NF-kappaB
    • Sen R. Control of B lymphocyte apoptosis by the transcription factor NF-kappaB. Immunity 2006;25:871-883
    • (2006) Immunity , vol.25 , pp. 871-883
    • Sen, R.1
  • 13
    • 0034982801 scopus 로고    scopus 로고
    • The TNF-receptor-associated factor family: Scaffold molecules for cytokine receptors, kinases and their regulators
    • Wajant H, Henkler F, Scheurich P. The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators. Cell Signal 2001;13:389-400.
    • (2001) Cell Signal , vol.13 , pp. 389-400
    • Wajant, H.1    Henkler, F.2    Scheurich, P.3
  • 15
    • 0033561039 scopus 로고    scopus 로고
    • TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling
    • Lomaga MA, Yeh WC, Sarosi I, et al. TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes Dev 1999;13:1015-1024
    • (1999) Genes Dev , vol.13 , pp. 1015-1024
    • Lomaga, M.A.1    Yeh, W.C.2    Sarosi, I.3
  • 16
    • 0028978626 scopus 로고
    • TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40
    • Rothe M, Sarma V, Dixit VM, Goeddel DV. TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40. Science 1995;269:1424-1427
    • (1995) Science , vol.269 , pp. 1424-1427
    • Rothe, M.1    Sarma, V.2    Dixit, V.M.3    Goeddel, D.V.4
  • 17
    • 2942731516 scopus 로고    scopus 로고
    • Regulation of the NF-kappaBinducing kinase by tumor necrosis factor receptor- associated factor 3-induced degradation
    • Liao G, Zhang M, Harhaj EW, Sun SC. Regulation of the NF-kappaBinducing kinase by tumor necrosis factor receptor- associated factor 3-induced degradation. J Biol Chem 2004;279:26243-26250
    • (2004) J Biol Chem , vol.279 , pp. 26243-26250
    • Liao, G.1    Zhang, M.2    Harhaj, E.W.3    Sun, S.C.4
  • 18
    • 8444220390 scopus 로고    scopus 로고
    • TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells
    • Grech AP, Amesbury M, Chan T, Gardam S, Basten A, Brink R. TRAF2 differentially regulates the canonical and noncanonical pathways of NF-kappaB activation in mature B cells. Immunity 2004;21:629-642
    • (2004) Immunity , vol.21 , pp. 629-642
    • Grech, A.P.1    Amesbury, M.2    Chan, T.3    Gardam, S.4    Basten, A.5    Brink, R.6
  • 19
    • 0029953942 scopus 로고    scopus 로고
    • Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor- associated factors
    • Uren AG, Pakusch M, Hawkins CJ, Puls KL, Vaux DL. Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor- associated factors. Proc Natl Acad Sci USA 1996;93:4974-4978
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4974-4978
    • Uren, A.G.1    Pakusch, M.2    Hawkins, C.J.3    Puls, K.L.4    Vaux, D.L.5
  • 21
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 1998;281:1680-1683
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin Jr., A.S.5
  • 22
    • 0030447483 scopus 로고    scopus 로고
    • The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex
    • Shu HB, Takeuchi M, Goeddel DV. The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex. Proc Natl Acad Sci USA 1996;93:13973-13978
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13973-13978
    • Shu, H.B.1    Takeuchi, M.2    Goeddel, D.V.3
  • 23
    • 36048999753 scopus 로고    scopus 로고
    • IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis
    • Varfolomeev E, Blankenship JW, Wayson SM, et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell 2007;131:669-681
    • (2007) Cell , vol.131 , pp. 669-681
    • Varfolomeev, E.1    Blankenship, J.W.2    Wayson, S.M.3
  • 24
    • 0029917841 scopus 로고    scopus 로고
    • TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation
    • Cheng G, Baltimore D. TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation. Genes Dev 1996;10:963-973
    • (1996) Genes Dev , vol.10 , pp. 963-973
    • Cheng, G.1    Baltimore, D.2
  • 26
    • 0037020147 scopus 로고    scopus 로고
    • Association of the adaptor TANK with the i kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases
    • Chariot A, Leonardi A, Muller J, Bonif M, Brown K, Siebenlist U. Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases. J Biol Chem 2002;277:37029-37036
    • (2002) J Biol Chem , vol.277 , pp. 37029-37036
    • Chariot, A.1    Leonardi, A.2    Muller, J.3    Bonif, M.4    Brown, K.5    Siebenlist, U.6
  • 27
    • 33644956702 scopus 로고    scopus 로고
    • TNFalpha- and IKKbetamediated TANK/I-TRAF phosphorylation: Implications for interaction with NEMO/IKKgamma and NF-kappaB activation
    • Bonif M, Meuwis MA, Close P, et al. TNFalpha- and IKKbetamediated TANK/I-TRAF phosphorylation: implications for interaction with NEMO/IKKgamma and NF-kappaB activation. Biochem J 2006;394:593-603.
    • (2006) Biochem J , vol.394 , pp. 593-603
    • Bonif, M.1    Meuwis, M.A.2    Close, P.3
  • 28
    • 0033485542 scopus 로고    scopus 로고
    • NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase
    • Pomerantz JL, Baltimore D. NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase. EMBO J 1999;18:6694-6704
    • (1999) EMBO J , vol.18 , pp. 6694-6704
    • Pomerantz, J.L.1    Baltimore, D.2
  • 29
    • 34250196771 scopus 로고    scopus 로고
    • Negative regulation of TCR signaling by NF-kappaB2/p100
    • Legarda-Addison D, Ting AT. Negative regulation of TCR signaling by NF-kappaB2/p100. J Immunol 2007;178:7767-7778
    • (2007) J Immunol , vol.178 , pp. 7767-7778
    • Legarda-Addison, D.1    Ting, A.T.2
  • 30
    • 12144286821 scopus 로고    scopus 로고
    • BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex
    • Hase H, Kanno Y, Kojima M, et al. BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex. Blood 2004;103:2257-2265
    • (2004) Blood , vol.103 , pp. 2257-2265
    • Hase, H.1    Kanno, Y.2    Kojima, M.3
  • 31
    • 0029665080 scopus 로고    scopus 로고
    • Role of IkappaBalpha ubiquitination in signal-induced activation of NFkappaB in vivo
    • Roff M, Thompson J, Rodriguez MS, et al. Role of IkappaBalpha ubiquitination in signal-induced activation of NFkappaB in vivo. J Biol Chem 1996;271:7844-7850
    • (1996) J Biol Chem , vol.271 , pp. 7844-7850
    • Roff, M.1    Thompson, J.2    Rodriguez, M.S.3
  • 32
    • 0032577443 scopus 로고    scopus 로고
    • HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation
    • Yin MJ, Christerson LB, Yamamoto Y, et al. HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation. Cell 1998;93:875-884
    • (1998) Cell , vol.93 , pp. 875-884
    • Yin, M.J.1    Christerson, L.B.2    Yamamoto, Y.3
  • 33
    • 0034745420 scopus 로고    scopus 로고
    • NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100
    • Xiao G, Harhaj EW, Sun SC. NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100. Mol Cell 2001;7:401-409
    • (2001) Mol Cell , vol.7 , pp. 401-409
    • Xiao, G.1    Harhaj, E.W.2    Sun, S.C.3
  • 34
    • 0034607655 scopus 로고    scopus 로고
    • Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
    • Yang Y, Fang S, Jensen JP, Weissman AM, Ashwell JD. Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. Science 2000;288:874-877
    • (2000) Science , vol.288 , pp. 874-877
    • Yang, Y.1    Fang, S.2    Jensen, J.P.3    Weissman, A.M.4    Ashwell, J.D.5
  • 35
    • 0842303313 scopus 로고    scopus 로고
    • Back to the future with ubiquitin
    • Pickart CM. Back to the future with ubiquitin. Cell 2004;116:181-190.
    • (2004) Cell , vol.116 , pp. 181-190
    • Pickart, C.M.1
  • 36
    • 0037149542 scopus 로고    scopus 로고
    • TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2
    • Li X, Yang Y, Ashwell JD. TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2. Nature 2002;416:345-347
    • (2002) Nature , vol.416 , pp. 345-347
    • Li, X.1    Yang, Y.2    Ashwell, J.D.3
  • 37
    • 0029595282 scopus 로고
    • The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins
    • Rothe M, Pan MG, Henzel WJ, Ayres TM, Goeddel DV. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell 1995;83:1243-1252
    • (1995) Cell , vol.83 , pp. 1243-1252
    • Rothe, M.1    Pan, M.G.2    Henzel, W.J.3    Ayres, T.M.4    Goeddel, D.V.5
  • 38
    • 0034733682 scopus 로고    scopus 로고
    • A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling
    • Chan FK, Chun HJ, Zheng L, Siegel RM, Bui KL, Lenardo MJ. A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. Science 2000;288: 2351-2354
    • (2000) Science , vol.288 , pp. 2351-2354
    • Chan, F.K.1    Chun, H.J.2    Zheng, L.3    Siegel, R.M.4    Bui, K.L.5    Lenardo, M.J.6
  • 39
    • 20044366916 scopus 로고    scopus 로고
    • Structures of APRILreceptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding
    • Hymowitz SG, Patel DR, Wallweber HJ, et al. Structures of APRILreceptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding. J Biol Chem 2005;280:7218-7227
    • (2005) J Biol Chem , vol.280 , pp. 7218-7227
    • Hymowitz, S.G.1    Patel, D.R.2    Wallweber, H.J.3
  • 40
    • 40249115896 scopus 로고    scopus 로고
    • TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor
    • Gardam S, Sierro F, Basten A, Mackay F, Brink R. TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor. Immunity 2008;28:391-401.
    • (2008) Immunity , vol.28 , pp. 391-401
    • Gardam, S.1    Sierro, F.2    Basten, A.3    MacKay, F.4    Brink, R.5
  • 41
    • 12944249540 scopus 로고    scopus 로고
    • Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
    • Khare SD, Sarosi I, Xia XZ, et al. Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice. Proc Natl Acad Sci USA 2000;97:3370-3375
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3370-3375
    • Khare, S.D.1    Sarosi, I.2    Xia, X.Z.3
  • 42
    • 0033428703 scopus 로고    scopus 로고
    • Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
    • Mackay F, Woodcock SA, Lawton P, et al. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med 1999;190:1697-1710
    • (1999) J Exp Med , vol.190 , pp. 1697-1710
    • MacKay, F.1    Woodcock, S.A.2    Lawton, P.3
  • 43
    • 0033198702 scopus 로고    scopus 로고
    • TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses
    • Nguyen LT, Duncan GS, Mirtsos C, et al. TRAF2 deficiency results in hyperactivity of certain TNFR1 signals and impairment of CD40-mediated responses. Immunity 1999;11:379-389
    • (1999) Immunity , vol.11 , pp. 379-389
    • Nguyen, L.T.1    Duncan, G.S.2    Mirtsos, C.3
  • 44
    • 0031463025 scopus 로고    scopus 로고
    • Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
    • Yeh WC, Shahinian A, Speiser D, et al. Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. Immunity 1997;7:715-725
    • (1997) Immunity , vol.7 , pp. 715-725
    • Yeh, W.C.1    Shahinian, A.2    Speiser, D.3
  • 45
    • 16244377737 scopus 로고    scopus 로고
    • Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo
    • Conze DB, Albert L, Ferrick DA, et al. Posttranscriptional downregulation of c-IAP2 by the ubiquitin protein ligase c-IAP1 in vivo. Mol Cell Biol 2005;25:3348-3356
    • (2005) Mol Cell Biol , vol.25 , pp. 3348-3356
    • Conze, D.B.1    Albert, L.2    Ferrick, D.A.3
  • 46
    • 17944375043 scopus 로고    scopus 로고
    • TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS
    • Gross JA, Dillon SR, Mudri S, et al. TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS. Immunity 2001;15:289-302.
    • (2001) Immunity , vol.15 , pp. 289-302
    • Gross, J.A.1    Dillon, S.R.2    Mudri, S.3
  • 47
    • 0345791504 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor-associated factor (TRAF) 1 regulates CD40- induced TRAF2-mediated NF-kappaB activation
    • Fotin-Mleczek M, Henkler F, Hausser A, et al. Tumor necrosis factor receptor-associated factor (TRAF) 1 regulates CD40- induced TRAF2-mediated NF-kappaB activation. J Biol Chem 2004;279:677-685
    • (2004) J Biol Chem , vol.279 , pp. 677-685
    • Fotin-Mleczek, M.1    Henkler, F.2    Hausser, A.3
  • 48
    • 0038529692 scopus 로고    scopus 로고
    • Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosis
    • Kuai J, Nickbarg E, Wooters J, Qiu Y, Wang J, Lin LL. Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosis. J Biol Chem 2003;278:14363-14369
    • (2003) J Biol Chem , vol.278 , pp. 14363-14369
    • Kuai, J.1    Nickbarg, E.2    Wooters, J.3    Qiu, Y.4    Wang, J.5    Lin, L.L.6
  • 49
    • 34547660308 scopus 로고    scopus 로고
    • Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma
    • Keats JJ, Fonseca R, Chesi M, et al. Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. Cancer Cell 2007;12:131-144
    • (2007) Cancer Cell , vol.12 , pp. 131-144
    • Keats, J.J.1    Fonseca, R.2    Chesi, M.3
  • 50
    • 0029785204 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor associated factor 2 is a mediator of NF-kappa B activation by latent infection membrane protein 1, the Epstein- Barr virus transforming protein
    • Kaye KM, Devergne O, Harada JN, et al. Tumor necrosis factor receptor associated factor 2 is a mediator of NF-kappa B activation by latent infection membrane protein 1, the Epstein- Barr virus transforming protein. Proc Natl Acad Sci USA 1996;93:11085-11090
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11085-11090
    • Kaye, K.M.1    Devergne, O.2    Harada, J.N.3
  • 51
    • 34547562418 scopus 로고    scopus 로고
    • Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma
    • Annunziata CM, Davis RE, Demchenko Y, et al. Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell 2007;12:115-130
    • (2007) Cancer Cell , vol.12 , pp. 115-130
    • Annunziata, C.M.1    Davis, R.E.2    Demchenko, Y.3
  • 52
    • 33748441252 scopus 로고    scopus 로고
    • Alternative and classical NF-kappa B signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease
    • Enzler T, Bonizzi G, Silverman GJ, et al. Alternative and classical NF-kappa B signaling retain autoreactive B cells in the splenic marginal zone and result in lupus-like disease. Immunity 2006;25:403-415
    • (2006) Immunity , vol.25 , pp. 403-415
    • Enzler, T.1    Bonizzi, G.2    Silverman, G.J.3


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