p38 and EGF receptor kinase-mediated activation of the phosphatidylinositol 3-kinase/Akt pathway is required for Zn2+-induced cyclooxygenase-2 expression

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 289, Issue 5 33-5, 2005, Pages

  Wu, Weidong ^a   Silbajoris, Robert A ^b   Whang, Young E ^a   Graves, Lee M ^a   Bromberg, Philip A ^a   Samet, James M ^b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Airway epithelial cell; Signal transduction; Zinc

Indexed keywords

CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; STRESS ACTIVATED PROTEIN KINASE; ZINC;

ADENOVIRUS; ARTICLE; BRONCHUS MUCOSA; CELL TYPE; CHROMOSOME 10; CHROMOSOME DELETION; CONTROLLED STUDY; HUMAN; HUMAN CELL; INFLAMMATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR INTRINSIC ACTIVITY; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BASE SEQUENCE; CELL LINE; CYCLOOXYGENASE 2; DNA, COMPLEMENTARY; ENZYME ACTIVATION; GENE EXPRESSION; HUMANS; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, MESSENGER; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; ZINC;

EID: 27144448384     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00197.2005     Document Type: Article

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