Cyclooxygenase-2 induction and prostaglandin E2 accumulation in squamous cell carcinoma as a consequence of epidermal growth factor receptor rctivation by imatinib mesylate

Journal of Experimental Therapeutics and Oncology

Volumn 4, Issue 4, 2004, Pages 317-325

  Johnson, Faye M ^a   Yang, Peiying ^a   Newman, Robert A ^a   Donato, Nicholas J ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

COX 2; Head and neck squamous cell carcinoma; Imatinib; Kinase inhibition; MAPK

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; BCR ABL PROTEIN; CRYSTAL VIOLET; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR; IMATINIB; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROSTAGLANDIN E2; STEM CELL FACTOR; STEROID;

ACUTE GENERALIZED EXANTHEMATOUS PUSTULOSIS; ARTHRALGIA; ARTICLE; AUTOCRINE EFFECT; CELL TRANSFORMATION; CONTROLLED STUDY; DOSE RESPONSE; EDEMA; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME INHIBITION; GASTROINTESTINAL STROMAL TUMOR; GENE EXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MYALGIA; MYELOID LEUKEMIA; PRIORITY JOURNAL; PUSTULOSIS; RASH; SIGNAL TRANSDUCTION; SKIN MANIFESTATION; SQUAMOUS CELL CARCINOMA; STEROID THERAPY; STEVENS JOHNSON SYNDROME; WESTERN BLOTTING;

ANTI-INFECTIVE AGENTS, LOCAL; ANTINEOPLASTIC AGENTS; ARACHIDONIC ACID; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CYCLOOXYGENASE 2; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; EICOSANOIDS; ENZYME ACTIVATION; GENTIAN VIOLET; HEAD AND NECK NEOPLASMS; HUMANS; MAP KINASE KINASE 1; MEMBRANE PROTEINS; PIPERAZINES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRIMIDINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; TIME FACTORS;

EID: 13244264870     PISSN: 13594117     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Yu, C., Krystal, G., Varticovksi, L., McKinstry, R., Rahmani, M., Dent, P., and Grant, S. Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells. Cancer Res, 62: 188-199, 2002.
2. Johnson, F. M., Talpaz, M., and Donato, N. J. Gleevec induces cell cycle arrest, apoptosis, and activation of MAPK in head and neck squamous carcinoma cells. In: Proceedings of the American Assocaition for Cancer Research, 2002, 4192.
3. Frasca, F., Vigneri, P., Vella, V., Vigneri, R., and Wang, J. Y. Tyrosine kinase inhibitor STI571 enhances thyroid cancer cell motile response to hepatocyte growth factor. Oncogene, 20: 3845-3856, 2001.
4. Krystal, G. W., Honsawek, S., Litz, J., and Buchdunger, E. The selective tyrosine kinase inhibitor STI571 inhibits small cell lung cancer growth. Clin Cancer Res, 6: 3319-3326, 2000.
5. Sheng, H., Williams, C. S., Shao, J., Liang, P., DuBois, R. N., and Beauchamp, R. D. Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway. J Biol Chem, 273: 22120-22127, 1998.
6. Matsuura, H., Sakaue, M., Subbaramaiah, K., Kamitani, H., Eling, T. E., Dannenberg, A. J., Tanabe, T., Inoue, H., Arata, J., and Jetten, A. M. Regulation of cyclooxygenase-2 by interferon gamma and transforming growth factor alpha in normal human epidermal keratinocytes and squamous carcinoma cells. Role of mitogen-activated protein kinases. J Biol Chem, 274: 29138-29148, 1999.
7. Pai, R., Soreghan, B., Szabo, I. L., Pavelka, M., Baatar, D., and Tarnawski, A. S. Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy. Nat Med, 8: 289-293, 2002.
8. Kempen, E. C., Yang, P., Felix, E., Madden, T., and Newman, R. A. Simultaneous quantification of arachidonic acid metabolites in cultured tumor cells using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. Anal Biochem, 297: 183-190, 2001.
9. Saha, D., Datta, P. K., Sheng, H., Morrow, J. D., Wada, M., Moses, H. L., and Beauchamp, R. D. Synergistic induction of cyclooxygenase-2 by transforming growth factor- beta1 and epidermal growth factor inhibits apoptosis in epithelial cells. Neoplasia, 1: 508-517, 1999.
10. Yan, Z., Subbaramaiah, K., Camilli, T., Zhang, F., Tanabe, T., McCaffrey, T. A., Dannenberg, A. J., and Weksler, B. B. Benzo[a]pyrene induces the transcription of cyclooxygenase-2 in vascular smooth muscle cells. Evidence for the involvement of extracellular signal-regulated kinase and NF-kappaB. J Biol Chem, 275: 4949-4955, 2000.
11. Zhang, Z., Sheng, H., Shao, J., Beauchamp, R. D., and DuBois, R. N. Posttranscriptional regulation of cyclooxygenase-2 in rat intestinal epithelial cells. Neoplasia, 2: 523-530, 2000.
12. Fan, X. M., Wong, B. C., Lin, M. C., Cho, C. H., Wang, W. P., Kung, H. F., and Lam, S. K. Interleukin-1 beta induces cyclooxygenase-2 expression in gastric cancer cells by the p38 and p44/42 mitogen-activated protein kinase signaling pathways. J Gastroenterol Hepatol, 16: 1098-1104, 2001.
13. Chen, W. and Bowden, G. T. Role of p38 mitogen-activated protein kinases in ultraviolet-B irradiation-induced activator protein 1 activation in human keratinocytes. Mol Carcinog, 28: 196-202, 2000.
14. Lee, D. W., Sung, M. W., Park, S. W., Seong, W. J., Roh, J. L., Park, B., Heo, D. S., and Kim, K. H. Increased cyclooxygenase-2 expression in human squamous cell carcinomas of the head and neck and inhibition of proliferation by nonsteroidal anti-inflammatory drugs. Anticancer Res, 22: 2089-2096, 2002.
15. Zweifel, B. S., Davis, T. W., Ornberg, R. L., and Masferrer, J. L. Direct evidence for a role of cyclooxygenase 2-derived prostaglandin E2 in human head and neck xenograft tumors. Cancer Res, 62: 6706-6711, 2002.
16. Ranelletti, F. O., Almadori, G., Rocca, B., Ferrandina, G., Ciabattoni, G., Habib, A., Galli, J., Maggiano, N., Gessi, M., and Lauriola, L. Prognostic significance of cyclooxygenase-2 in laryngeal squamous cell carcinoma. Int J Cancer, 95: 343-349, 2001.
17. Peng, B., Hayes, M., Resta, D., Racine-Poon, A., Druker, B. J., Talpaz, M., Sawyers, C. L., Rosamilia, M., Ford, J., Lloyd, P., and Capdeville, R. Pharmacokinetics and pharmacodynamics of imatinib in a phase I trial with chronic myeloid leukemia patients. J Clin Oncol, 22: 935-942, 2004.
18. Shureiqi, I., Chen, D., Lotan, R., Yang, P., Newman, R. A., Fischer, S. M., and Lippman, S. M. 15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. Cancer Res, 60: 6846-6850, 2000.
19. Tang, S., Bhatia, B., Maldonado, C. J., Yang, P., Newman, R. A., Liu, J., Chandra, D., Traag, J., Klein, R. D., Fischer, S. M., Chopra, D., Shen, J., Zhau, H. E., Chung, L. W., and Tang, D. G. Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells. J Biol Chem, 277: 16189-16201, 2002.
20. Druker, B. J., Talpaz, M., Resta, D. J., Peng, B., Buchdunger, E., Ford, J. M., Lydon, N. B., Kantarjian, H., Capdeville, R., Ohno-Jones, S., and Sawyers, C. L. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med, 344: 1031-1037, 2001.
21. Schwarz, M., Kreuzer, K. A., Baskaynak, G., Dorken, B., and le Coutre, P. Imatinib-induced acute generalized exanthematous pustulosis (AGEP) in two patients with chronic myeloid leukemia. Eur J Haematol, 69: 254-256, 2002.
22. Hsiao, L. T., Chung, H. M., Lin, J. T., Chiou, T. J., Liu, J. H., Fan, F. S., Wang, W. S., Yen, C. C., and Chen, P. M. Stevens-Johnson syndrome after treatment with STI571: a case report. Br J Haematol, 117: 620-622, 2002.
23. Konstantopoulos, K., Papadogianni, A., Dimopoulou, M., Kourelis, C., and Meletis, J. Pityriasis rosea associated with imatinib (STI571, Gleevec). Dermatology, 205: 172-173, 2002.
24. Ebnoether, M., Stentoft, J., Ford, J., Buhl, L., and Gratwohl, A. Cerebral oedema as a possible complication of treatment with imatinib. Lancet, 359: 1751-1752, 2002.
25. Badie, B., Schartner, J. M., Hagar, A. R., Prabakaran, S., Peebles, T. R., Bartley, B., Lapsiwala, S., Resnick, D. K., and Vorpahl, J. Microglia cyclooxygenase-2 activity in experimental gliomas: possible role in cerebral edema formation. Clin Cancer Res, 9: 872-877, 2003.