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Volumn 51, Issue 3, 2010, Pages 1765-1772

Glyceraldehyde-3-phosphate dehydrogenase in retinal microvasculature: Implications for the development and progression of diabetic retinopathy

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEXOSAMINE; PROTEIN KINASE C; NITRATE; RIBOSE;

EID: 77949879018     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4171     Document Type: Article
Times cited : (39)

References (43)
  • 1
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiology of diabetic complications: A unifying mechanism
    • Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes. 2005;54:1615-1625.
    • (2005) Diabetes , vol.54 , pp. 1615-1625
    • Brownlee, M.1
  • 2
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature. 2001;414:813-820.
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 3
    • 85047691537 scopus 로고    scopus 로고
    • Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells
    • Du X, Matsumura T, Edelstein D, et al. Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells. J Clin Invest. 2003; 112:1049-1057.
    • (2003) J Clin Invest , vol.112 , pp. 1049-1057
    • Du, X.1    Matsumura, T.2    Edelstein, D.3
  • 4
    • 63249102297 scopus 로고    scopus 로고
    • Role of glyceraldehyde 3-phosphate dehydrogenase in the development and progression of diabetic retinopathy
    • Kanwar M, Kowluru R. Role of glyceraldehyde 3-phosphate dehydrogenase in the development and progression of diabetic retinopathy. Diabetes. 2009;58:227-234.
    • (2009) Diabetes , vol.58 , pp. 227-234
    • Kanwar, M.1    Kowluru, R.2
  • 5
    • 2442693140 scopus 로고    scopus 로고
    • Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: A role in high glucose-induced apoptosis in retinal Muller cells
    • Kusner LL, Sarthy VP, Mohr S. Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: a role in high glucose-induced apoptosis in retinal Muller cells. Invest Ophthalmol Vis Sci. 2004; 45:1553-1561.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 1553-1561
    • Kusner, L.L.1    Sarthy, V.P.2    Mohr, S.3
  • 6
    • 0033753702 scopus 로고    scopus 로고
    • Response of capillary cell death to aminoguanidine predicts the development of retinopathy: Comparison of diabetes and galactosemia
    • Kern TS, Tang J, Mizutani M, Kowluru R, Nagraj R, Lorenzi M. Response of capillary cell death to aminoguanidine predicts the development of retinopathy: comparison of diabetes and galactosemia. Invest Ophthalmol Vis Sci. 2000;41:3972-3978.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 3972-3978
    • Kern, T.S.1    Tang, J.2    Mizutani, M.3    Kowluru, R.4    Nagraj, R.5    Lorenzi, M.6
  • 7
    • 0024528919 scopus 로고
    • Diabetic retinopathy
    • Kohner EM. Diabetic retinopathy. Br Med Bull. 1989;45:148-173.
    • (1989) Br Med Bull , vol.45 , pp. 148-173
    • Kohner, E.M.1
  • 8
    • 0028944962 scopus 로고
    • Hyperglycemia and microvascular and macrovascular disease in diabetes
    • Klein R. Hyperglycemia and microvascular and macrovascular disease in diabetes. Diabetes Care. 1995;18:258-268.
    • (1995) Diabetes Care , vol.18 , pp. 258-268
    • Klein, R.1
  • 9
    • 0036023314 scopus 로고    scopus 로고
    • Diabetes-induced activation of caspase-3 in retina: Effect of antioxidant therapy
    • Kowluru RA, Koppolu P. Diabetes-induced activation of caspase-3 in retina: effect of antioxidant therapy. Free Radic Res. 2002;36: 993-999.
    • (2002) Free Radic Res , vol.36 , pp. 993-999
    • Kowluru, R.A.1    Koppolu, P.2
  • 10
    • 0142221070 scopus 로고    scopus 로고
    • Diabetes-induced mitochondrial dysfunction in the retina
    • Kowluru RA, Abbas SN. Diabetes-induced mitochondrial dysfunction in the retina. Invest Ophthalmol Vis Sci. 2003;44:5327-5334.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 5327-5334
    • Kowluru, R.A.1    Abbas, S.N.2
  • 11
    • 33645964980 scopus 로고    scopus 로고
    • Role of mitochondrial superoxide dismutase in the development of diabetic retinopathy
    • Kowluru RA, Atasi L, Ho YS. Role of mitochondrial superoxide dismutase in the development of diabetic retinopathy. Invest Ophthalmol Vis Sci. 2006;47:1594-1599.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 1594-1599
    • Kowluru, R.A.1    Atasi, L.2    Ho, Y.S.3
  • 12
    • 68249116568 scopus 로고    scopus 로고
    • Translocation of H-Ras and its implications in the development of diabetic retinopathy
    • Kowluru RA, Kanwar M. Translocation of H-Ras and its implications in the development of diabetic retinopathy. Biochem Biophys Res Commun. 2009;387:461-466.
    • (2009) Biochem Biophys Res Commun , vol.387 , pp. 461-466
    • Kowluru, R.A.1    Kanwar, M.2
  • 13
    • 18844395611 scopus 로고    scopus 로고
    • The pathogenesis of diabetic complications: The role of DNA injury and poly(ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity
    • Kiss L, Szabo C. The pathogenesis of diabetic complications: the role of DNA injury and poly(ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity. Mem Inst Oswaldo Cruz. 2005;100:29-37.
    • (2005) Mem Inst Oswaldo Cruz , vol.100 , pp. 29-37
    • Kiss, L.1    Szabo, C.2
  • 14
    • 0036789145 scopus 로고    scopus 로고
    • Pericytes and the pathogenesis of diabetic retinopathy
    • Hammes HP, Lin J, Renner O, et al. Pericytes and the pathogenesis of diabetic retinopathy. Diabetes. 2002;51:3107-3112.
    • (2002) Diabetes , vol.51 , pp. 3107-3112
    • Hammes, H.P.1    Lin, J.2    Renner, O.3
  • 15
    • 0029973474 scopus 로고    scopus 로고
    • Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy
    • Mizutani M, Kern TS, Lorenzi M. Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy. J Clin Invest. 1996;97:2883-2890.
    • (1996) J Clin Invest , vol.97 , pp. 2883-2890
    • Mizutani, M.1    Kern, T.S.2    Lorenzi, M.3
  • 16
    • 0031026597 scopus 로고    scopus 로고
    • Abnormalities of retinal metabolism in diabetes or experimental galactosemia, IV: Antioxidant defense system
    • Kowluru RA, Kern TS, Engerman RL. Abnormalities of retinal metabolism in diabetes or experimental galactosemia, IV: antioxidant defense system. Free Radic Biol Med. 1997;22:587-592.
    • (1997) Free Radic Biol Med , vol.22 , pp. 587-592
    • Kowluru, R.A.1    Kern, T.S.2    Engerman, R.L.3
  • 17
    • 32044446735 scopus 로고    scopus 로고
    • Diabetic retinopathy, oxidative stress and antioxidants
    • Kowluru RA. Diabetic retinopathy, oxidative stress and antioxidants. Curr Top Nutraceut Res. 2005;3:209-218.
    • (2005) Curr Top Nutraceut Res , vol.3 , pp. 209-218
    • Kowluru, R.A.1
  • 18
    • 0034520652 scopus 로고    scopus 로고
    • Glyceraldehyde-3-phosphate dehydrogenase in neurodegeneration and apoptosis signaling
    • Tatton WG, Chalmers-Redman RM, Elstner M, et al. Glyceraldehyde-3-phosphate dehydrogenase in neurodegeneration and apoptosis signaling. J Neural Transm Suppl. 2000;60:77-100.
    • (2000) J Neural Transm Suppl , vol.60 , pp. 77-100
    • Tatton, W.G.1    Chalmers-Redman, R.M.2    Elstner, M.3
  • 19
    • 0035711473 scopus 로고    scopus 로고
    • Diabetes-induced elevations in retinal oxidative stress, protein kinase C and nitric oxide are inter-related
    • Kowluru RA. Diabetes-induced elevations in retinal oxidative stress, protein kinase C and nitric oxide are inter-related. Acta Diabetol. 2001;38:179-185.
    • (2001) Acta Diabetol , vol.38 , pp. 179-185
    • Kowluru, R.A.1
  • 20
    • 0034710891 scopus 로고    scopus 로고
    • Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation
    • Du XL, Edelstein D, Rossetti L, et al. Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. Proc Natl Acad Sci U S A. 2000; 97:12222-12226.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 12222-12226
    • Du, X.L.1    Edelstein, D.2    Rossetti, L.3
  • 21
    • 0037482960 scopus 로고    scopus 로고
    • The role of advanced glycation in the pathogenesis of diabetic retinopathy
    • Stitt AW. The role of advanced glycation in the pathogenesis of diabetic retinopathy. Exp Mol Pathol. 2003;75:95-108.
    • (2003) Exp Mol Pathol , vol.75 , pp. 95-108
    • Stitt, A.W.1
  • 22
    • 0037375171 scopus 로고    scopus 로고
    • The role of polyol pathway in glucose-induced apoptosis of cultured retinal pericytes
    • Miwa K, Nakamura J, Hamada Y, et al. The role of polyol pathway in glucose-induced apoptosis of cultured retinal pericytes. Diabetes Res Clin Pract. 2003;60:1-9.
    • (2003) Diabetes Res Clin Pract , vol.60 , pp. 1-9
    • Miwa, K.1    Nakamura, J.2    Hamada, Y.3
  • 23
    • 0035669567 scopus 로고    scopus 로고
    • Increased retinal endothelial cell monolayer permeability induced by the diabetic milieu: Role of advanced non-enzymatic glycation and polyol pathway activation
    • Leto G, Pricci F, Amadio L, et al. Increased retinal endothelial cell monolayer permeability induced by the diabetic milieu: role of advanced non-enzymatic glycation and polyol pathway activation. Diabetes Metab Res Rev. 2001;17:448-458.
    • (2001) Diabetes Metab Res Rev , vol.17 , pp. 448-458
    • Leto, G.1    Pricci, F.2    Amadio, L.3
  • 24
    • 23844452781 scopus 로고    scopus 로고
    • New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells
    • Sirover MA. New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells. J Cell Biochem. 2005;95:45-52.
    • (2005) J Cell Biochem , vol.95 , pp. 45-52
    • Sirover, M.A.1
  • 25
    • 0037342855 scopus 로고    scopus 로고
    • Effect of re-institution of good glycemic control on retinal oxidative stress and nitrative stress in diabetic rats
    • Kowluru RA. Effect of re-institution of good glycemic control on retinal oxidative stress and nitrative stress in diabetic rats. Diabetes. 2003;52:818-823.
    • (2003) Diabetes , vol.52 , pp. 818-823
    • Kowluru, R.A.1
  • 26
    • 34247394257 scopus 로고    scopus 로고
    • Oxidative stress and diabetic retinopathy
    • Kowluru RA, Chan PS. Oxidative stress and diabetic retinopathy. Exp Diabetes Res. 2007;2007:43603.
    • (2007) Exp Diabetes Res , pp. 43603
    • Kowluru, R.A.1    Chan, P.S.2
  • 27
    • 0034012849 scopus 로고    scopus 로고
    • Responses to peroxynitrite in yeast: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a sensitive intracellular target for nitration and enhancement of chaperone expression and ubiquitination
    • Buchczyk DP, Briviba K, Hartl FU, Sies H. Responses to peroxynitrite in yeast: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a sensitive intracellular target for nitration and enhancement of chaperone expression and ubiquitination. Biol Chem. 2000;381:121-126.
    • (2000) Biol Chem , vol.381 , pp. 121-126
    • Buchczyk, D.P.1    Briviba, K.2    Hartl, F.U.3    Sies, H.4
  • 28
    • 0033515479 scopus 로고    scopus 로고
    • Nitric oxide-induced S-glutathionylation and inactivation of glyceraldehyde-3-phosphate dehydrogenase
    • Mohr S, Hallak H, de Boitte A, Lapetina EG, Brüne B. Nitric oxide-induced S-glutathionylation and inactivation of glyceraldehyde-3-phosphate dehydrogenase. J Biol Chem. 1999;274:9427-9430.
    • (1999) J Biol Chem , vol.274 , pp. 9427-9430
    • Mohr, S.1    Hallak, H.2    de Boitte, A.3    Lapetina, E.G.4    Brüne, B.5
  • 29
    • 22144477159 scopus 로고    scopus 로고
    • S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding
    • Hara MR, Agrawal N, Kim SF, et al. S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding. Nat Cell Biol. 2005;7:665-674.
    • (2005) Nat Cell Biol , vol.7 , pp. 665-674
    • Hara, M.R.1    Agrawal, N.2    Kim, S.F.3
  • 30
    • 0029111530 scopus 로고
    • Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide
    • 89-88
    • Inoue S, Kawanishi S. Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide. FEBS Lett. 1995; 371:89-88.
    • (1995) FEBS Lett , vol.371
    • Inoue, S.1    Kawanishi, S.2
  • 31
    • 0028175539 scopus 로고
    • Mechanism of covalent modification of glyceraldehyde-3-phosphate dehydrogenase at its active site thiol by nitric oxide, peroxynitrite and related nitrosating agents
    • Mohr S, Stamler JS, Brüne B. Mechanism of covalent modification of glyceraldehyde-3-phosphate dehydrogenase at its active site thiol by nitric oxide, peroxynitrite and related nitrosating agents. FEBS Lett. 1994;348:223-227.
    • (1994) FEBS Lett , vol.348 , pp. 223-227
    • Mohr, S.1    Stamler, J.S.2    Brüne, B.3
  • 32
    • 0035136240 scopus 로고    scopus 로고
    • Diabetic endothelial dysfunction: The role of poly(ADP-ribose) polymerase activation
    • Garcia Soriano F, Virág L, Jagtap P, et al. Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med. 2001;7:108-113.
    • (2001) Nat Med , vol.7 , pp. 108-113
    • Garcia Soriano, F.1    Virág, L.2    Jagtap, P.3
  • 33
    • 0035851210 scopus 로고    scopus 로고
    • Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase
    • Soriano FG, Pacher P, Mabley J, Liaudet L, Szabó C. Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase. Circ Res. 2001;89:684-691.
    • (2001) Circ Res , vol.89 , pp. 684-691
    • Soriano, F.G.1    Pacher, P.2    Mabley, J.3    Liaudet, L.4    Szabó, C.5
  • 34
    • 7044229731 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-κB
    • Zheng L, Szabo C, Kern TS. Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-κB. Diabetes. 2004;53:2960-2967.
    • (2004) Diabetes , vol.53 , pp. 2960-2967
    • Zheng, L.1    Szabo, C.2    Kern, T.S.3
  • 35
    • 6344293916 scopus 로고    scopus 로고
    • Peroxynitrite decomposition catalyst, FP15, and poly(ADP-ribose) polymerase inhibitor, PJ34, inhibit leukocyte entrapment in the retinal microcirculation of diabetic rats
    • Sugawara R, Hikichi T, Kitaya N, et al. Peroxynitrite decomposition catalyst, FP15, and poly(ADP-ribose) polymerase inhibitor, PJ34, inhibit leukocyte entrapment in the retinal microcirculation of diabetic rats. Curr Eye Res. 2004;29:11-16.
    • (2004) Curr Eye Res , vol.29 , pp. 11-16
    • Sugawara, R.1    Hikichi, T.2    Kitaya, N.3
  • 36
    • 12144254266 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase inhibitors counteract diabetes-and hypoxia-induced retinal vascular endothelial growth factor overexpression
    • Obrosova IG, Minchenko AG, Frank RN, et al. Poly(ADP-ribose) polymerase inhibitors counteract diabetes-and hypoxia-induced retinal vascular endothelial growth factor overexpression. Int J Mol Med. 2004;14:55-64.
    • (2004) Int J Mol Med , vol.14 , pp. 55-64
    • Obrosova, I.G.1    Minchenko, A.G.2    Frank, R.N.3
  • 37
    • 0037454697 scopus 로고    scopus 로고
    • Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes
    • Beisswenger PJ, Howell SK, Smith K, Szwergold BS. Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes. Biochim Biophys Acta. 2003;1637:98-106.
    • (2003) Biochim Biophys Acta , vol.1637 , pp. 98-106
    • Beisswenger, P.J.1    Howell, S.K.2    Smith, K.3    Szwergold, B.S.4
  • 39
    • 0017638265 scopus 로고
    • Clinicopathologic correlations in diabetic retinopathy, II: Clinical and histologic appearances of retinal capillary microaneurysms
    • Bresnick GH, Davis MD, Myers FL, de Venecia G. Clinicopathologic correlations in diabetic retinopathy, II: clinical and histologic appearances of retinal capillary microaneurysms. Arch Ophthalmol. 1977;95:1215-1220.
    • (1977) Arch Ophthalmol , vol.95 , pp. 1215-1220
    • Bresnick, G.H.1    Davis, M.D.2    Myers, F.L.3    de Venecia, G.4
  • 40
    • 73149121384 scopus 로고    scopus 로고
    • Metabolic memory in diabetes-from in vitro oddity to in vivo problem: Role of apoptosis
    • In press
    • Kowluru RA, Chan PS. Metabolic memory in diabetes-from in vitro oddity to in vivo problem: role of apoptosis. Brain Res Bull. In press.
    • Brain Res Bull
    • Kowluru, R.A.1    Chan, P.S.2
  • 41
    • 0024420402 scopus 로고
    • Pathogenesis of diabetic retinopathy
    • Engerman RL. Pathogenesis of diabetic retinopathy. Diabetes. 1989;38:1203-1206.
    • (1989) Diabetes , vol.38 , pp. 1203-1206
    • Engerman, R.L.1
  • 42
    • 0031729874 scopus 로고    scopus 로고
    • Early worsening of diabetic retinopathy in the diabetes control and complication trial
    • Diabetes Control and Complications Trial Research Group
    • Diabetes Control and Complications Trial Research Group. Early worsening of diabetic retinopathy in the diabetes control and complication trial. Arch Ophthalmol. 1998;116:874-886.
    • (1998) Arch Ophthalmol , vol.116 , pp. 874-886
  • 43
    • 58149252632 scopus 로고    scopus 로고
    • Prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus: 10 years after the Diabetes Control and Complications Trial
    • White NH, Sun W, Cleary PA, et al. Prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus: 10 years after the Diabetes Control and Complications Trial. Arch Ophthalmol. 2008;126:1707-1715.
    • (2008) Arch Ophthalmol , vol.126 , pp. 1707-1715
    • White, N.H.1    Sun, W.2    Cleary, P.A.3


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