-
1
-
-
20044376702
-
The pathobiology of diabetic complications: A unifying mechanism
-
Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes. 2005;54:1615-1625.
-
(2005)
Diabetes
, vol.54
, pp. 1615-1625
-
-
Brownlee, M.1
-
2
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature. 2001;414:813-820.
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
3
-
-
85047691537
-
Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells
-
Du X, Matsumura T, Edelstein D, et al. Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells. J Clin Invest. 2003; 112:1049-1057.
-
(2003)
J Clin Invest
, vol.112
, pp. 1049-1057
-
-
Du, X.1
Matsumura, T.2
Edelstein, D.3
-
4
-
-
63249102297
-
Role of glyceraldehyde 3-phosphate dehydrogenase in the development and progression of diabetic retinopathy
-
Kanwar M, Kowluru R. Role of glyceraldehyde 3-phosphate dehydrogenase in the development and progression of diabetic retinopathy. Diabetes. 2009;58:227-234.
-
(2009)
Diabetes
, vol.58
, pp. 227-234
-
-
Kanwar, M.1
Kowluru, R.2
-
5
-
-
2442693140
-
Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: A role in high glucose-induced apoptosis in retinal Muller cells
-
Kusner LL, Sarthy VP, Mohr S. Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: a role in high glucose-induced apoptosis in retinal Muller cells. Invest Ophthalmol Vis Sci. 2004; 45:1553-1561.
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, pp. 1553-1561
-
-
Kusner, L.L.1
Sarthy, V.P.2
Mohr, S.3
-
6
-
-
0033753702
-
Response of capillary cell death to aminoguanidine predicts the development of retinopathy: Comparison of diabetes and galactosemia
-
Kern TS, Tang J, Mizutani M, Kowluru R, Nagraj R, Lorenzi M. Response of capillary cell death to aminoguanidine predicts the development of retinopathy: comparison of diabetes and galactosemia. Invest Ophthalmol Vis Sci. 2000;41:3972-3978.
-
(2000)
Invest Ophthalmol Vis Sci
, vol.41
, pp. 3972-3978
-
-
Kern, T.S.1
Tang, J.2
Mizutani, M.3
Kowluru, R.4
Nagraj, R.5
Lorenzi, M.6
-
7
-
-
0024528919
-
Diabetic retinopathy
-
Kohner EM. Diabetic retinopathy. Br Med Bull. 1989;45:148-173.
-
(1989)
Br Med Bull
, vol.45
, pp. 148-173
-
-
Kohner, E.M.1
-
8
-
-
0028944962
-
Hyperglycemia and microvascular and macrovascular disease in diabetes
-
Klein R. Hyperglycemia and microvascular and macrovascular disease in diabetes. Diabetes Care. 1995;18:258-268.
-
(1995)
Diabetes Care
, vol.18
, pp. 258-268
-
-
Klein, R.1
-
9
-
-
0036023314
-
Diabetes-induced activation of caspase-3 in retina: Effect of antioxidant therapy
-
Kowluru RA, Koppolu P. Diabetes-induced activation of caspase-3 in retina: effect of antioxidant therapy. Free Radic Res. 2002;36: 993-999.
-
(2002)
Free Radic Res
, vol.36
, pp. 993-999
-
-
Kowluru, R.A.1
Koppolu, P.2
-
10
-
-
0142221070
-
Diabetes-induced mitochondrial dysfunction in the retina
-
Kowluru RA, Abbas SN. Diabetes-induced mitochondrial dysfunction in the retina. Invest Ophthalmol Vis Sci. 2003;44:5327-5334.
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 5327-5334
-
-
Kowluru, R.A.1
Abbas, S.N.2
-
11
-
-
33645964980
-
Role of mitochondrial superoxide dismutase in the development of diabetic retinopathy
-
Kowluru RA, Atasi L, Ho YS. Role of mitochondrial superoxide dismutase in the development of diabetic retinopathy. Invest Ophthalmol Vis Sci. 2006;47:1594-1599.
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 1594-1599
-
-
Kowluru, R.A.1
Atasi, L.2
Ho, Y.S.3
-
12
-
-
68249116568
-
Translocation of H-Ras and its implications in the development of diabetic retinopathy
-
Kowluru RA, Kanwar M. Translocation of H-Ras and its implications in the development of diabetic retinopathy. Biochem Biophys Res Commun. 2009;387:461-466.
-
(2009)
Biochem Biophys Res Commun
, vol.387
, pp. 461-466
-
-
Kowluru, R.A.1
Kanwar, M.2
-
13
-
-
18844395611
-
The pathogenesis of diabetic complications: The role of DNA injury and poly(ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity
-
Kiss L, Szabo C. The pathogenesis of diabetic complications: the role of DNA injury and poly(ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity. Mem Inst Oswaldo Cruz. 2005;100:29-37.
-
(2005)
Mem Inst Oswaldo Cruz
, vol.100
, pp. 29-37
-
-
Kiss, L.1
Szabo, C.2
-
14
-
-
0036789145
-
Pericytes and the pathogenesis of diabetic retinopathy
-
Hammes HP, Lin J, Renner O, et al. Pericytes and the pathogenesis of diabetic retinopathy. Diabetes. 2002;51:3107-3112.
-
(2002)
Diabetes
, vol.51
, pp. 3107-3112
-
-
Hammes, H.P.1
Lin, J.2
Renner, O.3
-
15
-
-
0029973474
-
Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy
-
Mizutani M, Kern TS, Lorenzi M. Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy. J Clin Invest. 1996;97:2883-2890.
-
(1996)
J Clin Invest
, vol.97
, pp. 2883-2890
-
-
Mizutani, M.1
Kern, T.S.2
Lorenzi, M.3
-
16
-
-
0031026597
-
Abnormalities of retinal metabolism in diabetes or experimental galactosemia, IV: Antioxidant defense system
-
Kowluru RA, Kern TS, Engerman RL. Abnormalities of retinal metabolism in diabetes or experimental galactosemia, IV: antioxidant defense system. Free Radic Biol Med. 1997;22:587-592.
-
(1997)
Free Radic Biol Med
, vol.22
, pp. 587-592
-
-
Kowluru, R.A.1
Kern, T.S.2
Engerman, R.L.3
-
17
-
-
32044446735
-
Diabetic retinopathy, oxidative stress and antioxidants
-
Kowluru RA. Diabetic retinopathy, oxidative stress and antioxidants. Curr Top Nutraceut Res. 2005;3:209-218.
-
(2005)
Curr Top Nutraceut Res
, vol.3
, pp. 209-218
-
-
Kowluru, R.A.1
-
18
-
-
0034520652
-
Glyceraldehyde-3-phosphate dehydrogenase in neurodegeneration and apoptosis signaling
-
Tatton WG, Chalmers-Redman RM, Elstner M, et al. Glyceraldehyde-3-phosphate dehydrogenase in neurodegeneration and apoptosis signaling. J Neural Transm Suppl. 2000;60:77-100.
-
(2000)
J Neural Transm Suppl
, vol.60
, pp. 77-100
-
-
Tatton, W.G.1
Chalmers-Redman, R.M.2
Elstner, M.3
-
19
-
-
0035711473
-
Diabetes-induced elevations in retinal oxidative stress, protein kinase C and nitric oxide are inter-related
-
Kowluru RA. Diabetes-induced elevations in retinal oxidative stress, protein kinase C and nitric oxide are inter-related. Acta Diabetol. 2001;38:179-185.
-
(2001)
Acta Diabetol
, vol.38
, pp. 179-185
-
-
Kowluru, R.A.1
-
20
-
-
0034710891
-
Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation
-
Du XL, Edelstein D, Rossetti L, et al. Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. Proc Natl Acad Sci U S A. 2000; 97:12222-12226.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12222-12226
-
-
Du, X.L.1
Edelstein, D.2
Rossetti, L.3
-
21
-
-
0037482960
-
The role of advanced glycation in the pathogenesis of diabetic retinopathy
-
Stitt AW. The role of advanced glycation in the pathogenesis of diabetic retinopathy. Exp Mol Pathol. 2003;75:95-108.
-
(2003)
Exp Mol Pathol
, vol.75
, pp. 95-108
-
-
Stitt, A.W.1
-
22
-
-
0037375171
-
The role of polyol pathway in glucose-induced apoptosis of cultured retinal pericytes
-
Miwa K, Nakamura J, Hamada Y, et al. The role of polyol pathway in glucose-induced apoptosis of cultured retinal pericytes. Diabetes Res Clin Pract. 2003;60:1-9.
-
(2003)
Diabetes Res Clin Pract
, vol.60
, pp. 1-9
-
-
Miwa, K.1
Nakamura, J.2
Hamada, Y.3
-
23
-
-
0035669567
-
Increased retinal endothelial cell monolayer permeability induced by the diabetic milieu: Role of advanced non-enzymatic glycation and polyol pathway activation
-
Leto G, Pricci F, Amadio L, et al. Increased retinal endothelial cell monolayer permeability induced by the diabetic milieu: role of advanced non-enzymatic glycation and polyol pathway activation. Diabetes Metab Res Rev. 2001;17:448-458.
-
(2001)
Diabetes Metab Res Rev
, vol.17
, pp. 448-458
-
-
Leto, G.1
Pricci, F.2
Amadio, L.3
-
24
-
-
23844452781
-
New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells
-
Sirover MA. New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells. J Cell Biochem. 2005;95:45-52.
-
(2005)
J Cell Biochem
, vol.95
, pp. 45-52
-
-
Sirover, M.A.1
-
25
-
-
0037342855
-
Effect of re-institution of good glycemic control on retinal oxidative stress and nitrative stress in diabetic rats
-
Kowluru RA. Effect of re-institution of good glycemic control on retinal oxidative stress and nitrative stress in diabetic rats. Diabetes. 2003;52:818-823.
-
(2003)
Diabetes
, vol.52
, pp. 818-823
-
-
Kowluru, R.A.1
-
26
-
-
34247394257
-
Oxidative stress and diabetic retinopathy
-
Kowluru RA, Chan PS. Oxidative stress and diabetic retinopathy. Exp Diabetes Res. 2007;2007:43603.
-
(2007)
Exp Diabetes Res
, pp. 43603
-
-
Kowluru, R.A.1
Chan, P.S.2
-
27
-
-
0034012849
-
Responses to peroxynitrite in yeast: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a sensitive intracellular target for nitration and enhancement of chaperone expression and ubiquitination
-
Buchczyk DP, Briviba K, Hartl FU, Sies H. Responses to peroxynitrite in yeast: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a sensitive intracellular target for nitration and enhancement of chaperone expression and ubiquitination. Biol Chem. 2000;381:121-126.
-
(2000)
Biol Chem
, vol.381
, pp. 121-126
-
-
Buchczyk, D.P.1
Briviba, K.2
Hartl, F.U.3
Sies, H.4
-
28
-
-
0033515479
-
Nitric oxide-induced S-glutathionylation and inactivation of glyceraldehyde-3-phosphate dehydrogenase
-
Mohr S, Hallak H, de Boitte A, Lapetina EG, Brüne B. Nitric oxide-induced S-glutathionylation and inactivation of glyceraldehyde-3-phosphate dehydrogenase. J Biol Chem. 1999;274:9427-9430.
-
(1999)
J Biol Chem
, vol.274
, pp. 9427-9430
-
-
Mohr, S.1
Hallak, H.2
de Boitte, A.3
Lapetina, E.G.4
Brüne, B.5
-
29
-
-
22144477159
-
S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding
-
Hara MR, Agrawal N, Kim SF, et al. S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding. Nat Cell Biol. 2005;7:665-674.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 665-674
-
-
Hara, M.R.1
Agrawal, N.2
Kim, S.F.3
-
30
-
-
0029111530
-
Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide
-
89-88
-
Inoue S, Kawanishi S. Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide. FEBS Lett. 1995; 371:89-88.
-
(1995)
FEBS Lett
, vol.371
-
-
Inoue, S.1
Kawanishi, S.2
-
31
-
-
0028175539
-
Mechanism of covalent modification of glyceraldehyde-3-phosphate dehydrogenase at its active site thiol by nitric oxide, peroxynitrite and related nitrosating agents
-
Mohr S, Stamler JS, Brüne B. Mechanism of covalent modification of glyceraldehyde-3-phosphate dehydrogenase at its active site thiol by nitric oxide, peroxynitrite and related nitrosating agents. FEBS Lett. 1994;348:223-227.
-
(1994)
FEBS Lett
, vol.348
, pp. 223-227
-
-
Mohr, S.1
Stamler, J.S.2
Brüne, B.3
-
32
-
-
0035136240
-
Diabetic endothelial dysfunction: The role of poly(ADP-ribose) polymerase activation
-
Garcia Soriano F, Virág L, Jagtap P, et al. Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med. 2001;7:108-113.
-
(2001)
Nat Med
, vol.7
, pp. 108-113
-
-
Garcia Soriano, F.1
Virág, L.2
Jagtap, P.3
-
33
-
-
0035851210
-
Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase
-
Soriano FG, Pacher P, Mabley J, Liaudet L, Szabó C. Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase. Circ Res. 2001;89:684-691.
-
(2001)
Circ Res
, vol.89
, pp. 684-691
-
-
Soriano, F.G.1
Pacher, P.2
Mabley, J.3
Liaudet, L.4
Szabó, C.5
-
34
-
-
7044229731
-
Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-κB
-
Zheng L, Szabo C, Kern TS. Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-κB. Diabetes. 2004;53:2960-2967.
-
(2004)
Diabetes
, vol.53
, pp. 2960-2967
-
-
Zheng, L.1
Szabo, C.2
Kern, T.S.3
-
35
-
-
6344293916
-
Peroxynitrite decomposition catalyst, FP15, and poly(ADP-ribose) polymerase inhibitor, PJ34, inhibit leukocyte entrapment in the retinal microcirculation of diabetic rats
-
Sugawara R, Hikichi T, Kitaya N, et al. Peroxynitrite decomposition catalyst, FP15, and poly(ADP-ribose) polymerase inhibitor, PJ34, inhibit leukocyte entrapment in the retinal microcirculation of diabetic rats. Curr Eye Res. 2004;29:11-16.
-
(2004)
Curr Eye Res
, vol.29
, pp. 11-16
-
-
Sugawara, R.1
Hikichi, T.2
Kitaya, N.3
-
36
-
-
12144254266
-
Poly(ADP-ribose) polymerase inhibitors counteract diabetes-and hypoxia-induced retinal vascular endothelial growth factor overexpression
-
Obrosova IG, Minchenko AG, Frank RN, et al. Poly(ADP-ribose) polymerase inhibitors counteract diabetes-and hypoxia-induced retinal vascular endothelial growth factor overexpression. Int J Mol Med. 2004;14:55-64.
-
(2004)
Int J Mol Med
, vol.14
, pp. 55-64
-
-
Obrosova, I.G.1
Minchenko, A.G.2
Frank, R.N.3
-
37
-
-
0037454697
-
Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes
-
Beisswenger PJ, Howell SK, Smith K, Szwergold BS. Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes. Biochim Biophys Acta. 2003;1637:98-106.
-
(2003)
Biochim Biophys Acta
, vol.1637
, pp. 98-106
-
-
Beisswenger, P.J.1
Howell, S.K.2
Smith, K.3
Szwergold, B.S.4
-
39
-
-
0017638265
-
Clinicopathologic correlations in diabetic retinopathy, II: Clinical and histologic appearances of retinal capillary microaneurysms
-
Bresnick GH, Davis MD, Myers FL, de Venecia G. Clinicopathologic correlations in diabetic retinopathy, II: clinical and histologic appearances of retinal capillary microaneurysms. Arch Ophthalmol. 1977;95:1215-1220.
-
(1977)
Arch Ophthalmol
, vol.95
, pp. 1215-1220
-
-
Bresnick, G.H.1
Davis, M.D.2
Myers, F.L.3
de Venecia, G.4
-
40
-
-
73149121384
-
Metabolic memory in diabetes-from in vitro oddity to in vivo problem: Role of apoptosis
-
In press
-
Kowluru RA, Chan PS. Metabolic memory in diabetes-from in vitro oddity to in vivo problem: role of apoptosis. Brain Res Bull. In press.
-
Brain Res Bull
-
-
Kowluru, R.A.1
Chan, P.S.2
-
41
-
-
0024420402
-
Pathogenesis of diabetic retinopathy
-
Engerman RL. Pathogenesis of diabetic retinopathy. Diabetes. 1989;38:1203-1206.
-
(1989)
Diabetes
, vol.38
, pp. 1203-1206
-
-
Engerman, R.L.1
-
42
-
-
0031729874
-
Early worsening of diabetic retinopathy in the diabetes control and complication trial
-
Diabetes Control and Complications Trial Research Group
-
Diabetes Control and Complications Trial Research Group. Early worsening of diabetic retinopathy in the diabetes control and complication trial. Arch Ophthalmol. 1998;116:874-886.
-
(1998)
Arch Ophthalmol
, vol.116
, pp. 874-886
-
-
-
43
-
-
58149252632
-
Prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus: 10 years after the Diabetes Control and Complications Trial
-
White NH, Sun W, Cleary PA, et al. Prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus: 10 years after the Diabetes Control and Complications Trial. Arch Ophthalmol. 2008;126:1707-1715.
-
(2008)
Arch Ophthalmol
, vol.126
, pp. 1707-1715
-
-
White, N.H.1
Sun, W.2
Cleary, P.A.3
|