Complement regulator CD59 protects against angiotensin II-induced abdominal aortic aneurysms in mice

Circulation

Volumn 121, Issue 11, 2010, Pages 1338-1346

  Wu, Gongxiong ^a,b,c   Chen, Ting ^a,b   Shahsafaei, Aliakbar ^a   Hu, Weiguo ^a,b   Bronson, Roderick T ^b   Shi, Guo Ping ^a   Halperin, Jose A ^a,b   Aktas, Huseyin ^a,b   Qin, Xuebin ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

Aortic aneurysm, abdominal; CD59 antigen; Complement; Matrix metalloproteinase 2

Indexed keywords

ANGIOTENSIN II; APOENZYME; CD59 ANTIGEN; COMPLEMENT MEMBRANE ATTACK COMPLEX; GELATINASE A; GELATINASE B; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN C FOS; PROTEIN C JUN; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR AP 1;

ABDOMINAL AORTA ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; FEMALE; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANGIOTENSIN II; ANIMALS; ANTIGENS, CD59; AORTIC ANEURYSM, ABDOMINAL; APOLIPOPROTEINS E; COMPLEMENT MEMBRANE ATTACK COMPLEX; COMPLEMENT SYSTEM PROTEINS; FEMALE; HUMANS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MODELS, ANIMAL; NF-KAPPA B; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 77949868002     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.108.844589     Document Type: Article

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