메뉴 건너뛰기




Volumn 60, Issue 4, 2010, Pages 291-297

Immunostaining of gastric cancer with neuroendocrine differentiation: Reg IV-positive neuroendocrine cells are associated with gastrin, serotonin, pancreatic polypeptide and somatostatin

Author keywords

Gastric cancer; Gastrin; Neuroendocrine differentiation; Reg IV; Serotonin

Indexed keywords

CALCITONIN; CHROMOGRANIN A; GASTRIN; GASTRIN RELEASING PEPTIDE; GLUCAGON; NERVE CELL ADHESION MOLECULE; PANCREAS POLYPEPTIDE; PROTEIN; PROTEIN REG IV; SEROTONIN; SOMATOSTATIN; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

EID: 77949663900     PISSN: 13205463     EISSN: 14401827     Source Type: Journal    
DOI: 10.1111/j.1440-1827.2010.02519.x     Document Type: Article
Times cited : (12)

References (36)
  • 1
    • 0023749637 scopus 로고
    • Endocrine differentiation of gastric adenocarcinoma. the prevalence as evaluated by immunoreactive chromogranin A and its biologic significance
    • Ooi A, Mai M, Ogino T et al. Endocrine differentiation of gastric adenocarcinoma. The prevalence as evaluated by immunoreactive chromogranin A and its biologic significance. Cancer 1988 62 : 1096 1104.
    • (1988) Cancer , vol.62 , pp. 1096-1104
    • Ooi, A.1    Mai, M.2    Ogino, T.3
  • 2
    • 0033711705 scopus 로고    scopus 로고
    • Detection of chromogranin A in human gastric adenocarcinomas using a sensitive immunohistochemical technique
    • Qvigstad G, Sandvik AK, Brenna E, Aase S, Waldum HL. Detection of chromogranin A in human gastric adenocarcinomas using a sensitive immunohistochemical technique. Histochem J 2000 32 : 551 556.
    • (2000) Histochem J , vol.32 , pp. 551-556
    • Qvigstad, G.1    Sandvik, A.K.2    Brenna, E.3    Aase, S.4    Waldum, H.L.5
  • 3
    • 0020040122 scopus 로고
    • Scirrhous argyrophil cell carcinoma of the stomach with multiple production of polypeptide hormones, amine, CEA, lysozyme, and HCG
    • Tahara E, Ito H, Nakagami K, Shimamoto F, Yamamoto M, Sumii K. Scirrhous argyrophil cell carcinoma of the stomach with multiple production of polypeptide hormones, amine, CEA, lysozyme, and HCG. Cancer 1982 49 : 1904 1915.
    • (1982) Cancer , vol.49 , pp. 1904-1915
    • Tahara, E.1    Ito, H.2    Nakagami, K.3    Shimamoto, F.4    Yamamoto, M.5    Sumii, K.6
  • 4
    • 0022878185 scopus 로고
    • Serotonin in tubular adenomas, adenocarcinomas and endocrine tumours of the stomach. An immunohistochemical study
    • Ito H, Hata J, Oda N, Miyamori S, Tahara E. Serotonin in tubular adenomas, adenocarcinomas and endocrine tumours of the stomach. An immunohistochemical study. Virchows Arch A Pathol Anat Histopathol 1986 410 : 239 245.
    • (1986) Virchows Arch A Pathol Anat Histopathol , vol.410 , pp. 239-245
    • Ito, H.1    Hata, J.2    Oda, N.3    Miyamori, S.4    Tahara, E.5
  • 7
    • 18844457312 scopus 로고    scopus 로고
    • Enteroendocrine tumors other than carcinoid: A review of clinically significant advances
    • Warner RR. Enteroendocrine tumors other than carcinoid: A review of clinically significant advances. Gastroenterology 2005 128 : 1668 1684.
    • (2005) Gastroenterology , vol.128 , pp. 1668-1684
    • Warner, R.R.1
  • 9
    • 60649115305 scopus 로고    scopus 로고
    • Transcriptome dissection of gastric cancer: Identification of novel diagnostic and therapeutic targets from pathology specimens
    • Yasui W, Oue N, Sentani K et al. Transcriptome dissection of gastric cancer: Identification of novel diagnostic and therapeutic targets from pathology specimens. Pathol Int 2009 59 : 121 136.
    • (2009) Pathol Int , vol.59 , pp. 121-136
    • Yasui, W.1    Oue, N.2    Sentani, K.3
  • 10
    • 1942474530 scopus 로고    scopus 로고
    • Gene expression profile of gastric carcinoma: Identification of genes and tags potentially involved in invasion, metastasis, and carcinogenesis by serial analysis of gene expression
    • Oue N, Hamai Y, Mitani Y et al. Gene expression profile of gastric carcinoma: Identification of genes and tags potentially involved in invasion, metastasis, and carcinogenesis by serial analysis of gene expression. Cancer Res 2004 64 : 2397 2405.
    • (2004) Cancer Res , vol.64 , pp. 2397-2405
    • Oue, N.1    Hamai, Y.2    Mitani, Y.3
  • 11
    • 33646155334 scopus 로고    scopus 로고
    • Systematic search for gastric cancer-specific genes based on SAGE data: Melanoma inhibitory activity and matrix metalloproteinase-10 are novel prognostic factors in patients with gastric cancer
    • Aung PP, Oue N, Mitani Y et al. Systematic search for gastric cancer-specific genes based on SAGE data: Melanoma inhibitory activity and matrix metalloproteinase-10 are novel prognostic factors in patients with gastric cancer. Oncogene 2006 25 : 2546 2557.
    • (2006) Oncogene , vol.25 , pp. 2546-2557
    • Aung, P.P.1    Oue, N.2    Mitani, Y.3
  • 12
    • 49249128970 scopus 로고    scopus 로고
    • Immunohistochemical staining of Reg IV and claudin-18 is useful in the diagnosis of gastrointestinal signet ring cell carcinoma
    • Sentani K, Oue N, Tashiro T et al. Immunohistochemical staining of Reg IV and claudin-18 is useful in the diagnosis of gastrointestinal signet ring cell carcinoma. Am J Surg Pathol 2008 32 : 1182 1189.
    • (2008) Am J Surg Pathol , vol.32 , pp. 1182-1189
    • Sentani, K.1    Oue, N.2    Tashiro, T.3
  • 13
    • 0035897122 scopus 로고    scopus 로고
    • Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family: Reg IV
    • Hartupee JC, Zhang H, Bonaldo MF, Soares MB, Dieckgraefe BK. Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family: Reg IV. Biochim Biophys Acta 2001 1518 : 287 293.
    • (2001) Biochim Biophys Acta , vol.1518 , pp. 287-293
    • Hartupee, J.C.1    Zhang, H.2    Bonaldo, M.F.3    Soares, M.B.4    Dieckgraefe, B.K.5
  • 14
    • 39049171987 scopus 로고    scopus 로고
    • Serum concentration of Reg IV in patients with colorectal cancer: Overexpression and high serum levels of Reg IV are associated with liver metastasis
    • Oue N, Kuniyasu H, Noguchi T et al. Serum concentration of Reg IV in patients with colorectal cancer: Overexpression and high serum levels of Reg IV are associated with liver metastasis. Oncology 2007 72 : 371 380.
    • (2007) Oncology , vol.72 , pp. 371-380
    • Oue, N.1    Kuniyasu, H.2    Noguchi, T.3
  • 15
    • 33748932541 scopus 로고    scopus 로고
    • Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4
    • Takehara A, Eguchi H, Ohigashi H et al. Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4. Cancer Sci 2006 97 : 1191 1197.
    • (2006) Cancer Sci , vol.97 , pp. 1191-1197
    • Takehara, A.1    Eguchi, H.2    Ohigashi, H.3
  • 16
    • 49749083010 scopus 로고    scopus 로고
    • Reg IV is an independent prognostic factor for relapse in patients with clinically localized prostate cancer
    • Ohara S, Oue N, Matsubara A et al. Reg IV is an independent prognostic factor for relapse in patients with clinically localized prostate cancer. Cancer Sci 2008 99 : 1570 1577.
    • (2008) Cancer Sci , vol.99 , pp. 1570-1577
    • Ohara, S.1    Oue, N.2    Matsubara, A.3
  • 17
    • 57049118967 scopus 로고    scopus 로고
    • Reg IV expression is associated with cell growth and prognosis of adenoid cystic carcinoma in the salivary gland
    • Sasahira T, Oue N, Kirita T et al. Reg IV expression is associated with cell growth and prognosis of adenoid cystic carcinoma in the salivary gland. Histopathology 2008 53 : 667 675.
    • (2008) Histopathology , vol.53 , pp. 667-675
    • Sasahira, T.1    Oue, N.2    Kirita, T.3
  • 18
    • 26044463766 scopus 로고    scopus 로고
    • Expression and localization of Reg IV in human neoplastic and non-neoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinoma
    • Oue N, Mitani Y, Aung PP et al. Expression and localization of Reg IV in human neoplastic and non-neoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinoma. J Pathol 2005 207 : 185 198.
    • (2005) J Pathol , vol.207 , pp. 185-198
    • Oue, N.1    Mitani, Y.2    Aung, P.P.3
  • 19
    • 0003412927 scopus 로고    scopus 로고
    • Sobin, L.H. Wittekind, C.H. eds. edn. New York. John Wiley & Sons
    • Sobin LH, Wittekind CH, eds. TNM Classification of Malignant Tumors, 6th edn. New York : John Wiley & Sons, 2002 65 8.
    • (2002) TNM Classification of Malignant Tumors, 6th , pp. 65-8
  • 20
    • 12644292106 scopus 로고
    • The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma: An attempt at a histo-clinical classification
    • Lauren P. The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma: An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 1965 64 : 31 49.
    • (1965) Acta Pathol Microbiol Scand , vol.64 , pp. 31-49
    • Lauren, P.1
  • 21
    • 58149352926 scopus 로고    scopus 로고
    • Positive immunohistochemical staining of gammaH2AX is associated with tumor progression in gastric cancers from radiation-exposed patients
    • Sentani K, Oue N, Sakamoto N et al. Positive immunohistochemical staining of gammaH2AX is associated with tumor progression in gastric cancers from radiation-exposed patients. Oncol Rep 2008 20 : 1131 1136.
    • (2008) Oncol Rep , vol.20 , pp. 1131-1136
    • Sentani, K.1    Oue, N.2    Sakamoto, N.3
  • 22
    • 33644857438 scopus 로고    scopus 로고
    • Identification of mouse genes with highly specific expression patterns in differentiated intestinal epithelium
    • Schroder N, Sekhar A, Geffers I et al. Identification of mouse genes with highly specific expression patterns in differentiated intestinal epithelium. Gastroenterology 2006 130 : 902 907.
    • (2006) Gastroenterology , vol.130 , pp. 902-907
    • Schroder, N.1    Sekhar, A.2    Geffers, I.3
  • 23
    • 17344392128 scopus 로고    scopus 로고
    • Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis
    • Mallo GV, Rechreche H, Frigerio JM et al. Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis. Int J Cancer 1997 74 : 35 44.
    • (1997) Int J Cancer , vol.74 , pp. 35-44
    • Mallo, G.V.1    Rechreche, H.2    Frigerio, J.M.3
  • 25
    • 0036180974 scopus 로고    scopus 로고
    • Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice
    • Silberg DG, Sullivan J, Kang E et al. Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice. Gastroenterology 2002 122 : 689 696.
    • (2002) Gastroenterology , vol.122 , pp. 689-696
    • Silberg, D.G.1    Sullivan, J.2    Kang, E.3
  • 26
    • 18244362326 scopus 로고    scopus 로고
    • Ectopic expression of homeodomain protein CDX2 in intestinal metaplasia and carcinomas of the stomach
    • Bai YQ, Yamamoto H, Akiyama Y et al. Ectopic expression of homeodomain protein CDX2 in intestinal metaplasia and carcinomas of the stomach. Cancer Lett 2002 176 : 47 55.
    • (2002) Cancer Lett , vol.176 , pp. 47-55
    • Bai, Y.Q.1    Yamamoto, H.2    Akiyama, Y.3
  • 27
    • 0037221727 scopus 로고    scopus 로고
    • Expression of intestine-specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas
    • Almeida R, Silva E, Santos-Silva F et al. Expression of intestine-specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas. J Pathol 2003 199 : 36 40.
    • (2003) J Pathol , vol.199 , pp. 36-40
    • Almeida, R.1    Silva, E.2    Santos-Silva, F.3
  • 28
    • 0037462878 scopus 로고    scopus 로고
    • Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expression
    • Yamamoto H, Bai YQ, Yuasa Y. Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expression. Biochem Biophys Res Commun 2003 300 : 813 818.
    • (2003) Biochem Biophys Res Commun , vol.300 , pp. 813-818
    • Yamamoto, H.1    Bai, Y.Q.2    Yuasa, Y.3
  • 29
    • 0037097981 scopus 로고    scopus 로고
    • Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity
    • Lee CS, Perreault N, Brestelli JE, Kaestner KH. Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity. Genes Dev 2002 16 : 1488 1497.
    • (2002) Genes Dev , vol.16 , pp. 1488-1497
    • Lee, C.S.1    Perreault, N.2    Brestelli, J.E.3    Kaestner, K.H.4
  • 30
    • 30044442435 scopus 로고    scopus 로고
    • Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas
    • Bishnupuri KS, Luo Q, Murmu N, Houchen CW, Anant S, Dieckgraefe BK. Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas. Gastroenterology 2006 130 : 137 149.
    • (2006) Gastroenterology , vol.130 , pp. 137-149
    • Bishnupuri, K.S.1    Luo, Q.2    Murmu, N.3    Houchen, C.W.4    Anant, S.5    Dieckgraefe, B.K.6
  • 31
    • 34347348170 scopus 로고    scopus 로고
    • Reg IV is a serum biomarker for gastric cancer patients and predicts response to 5-fluorouracil-based chemotherapy
    • Mitani Y, Oue N, Matsumura S et al. Reg IV is a serum biomarker for gastric cancer patients and predicts response to 5-fluorouracil-based chemotherapy. Oncogene 2007 26 : 4383 4393.
    • (2007) Oncogene , vol.26 , pp. 4383-4393
    • Mitani, Y.1    Oue, N.2    Matsumura, S.3
  • 32
    • 0032934334 scopus 로고    scopus 로고
    • Gastrin induces heparin-binding epidermal growth factor-like growth factor in rat gastric epithelial cells transfected with gastrin receptor
    • Miyazaki Y, Shinomura Y, Tsutsui S et al. Gastrin induces heparin-binding epidermal growth factor-like growth factor in rat gastric epithelial cells transfected with gastrin receptor. Gastroenterology 1999 116 : 78 89.
    • (1999) Gastroenterology , vol.116 , pp. 78-89
    • Miyazaki, Y.1    Shinomura, Y.2    Tsutsui, S.3
  • 33
    • 0023090966 scopus 로고
    • Stimulation of gastrin release by bombesin and canine gastrin-releasing peptides. Studies with isolated canine G cells in primary culture
    • Sugano K, Park J, Soll AH, Yamada T. Stimulation of gastrin release by bombesin and canine gastrin-releasing peptides. Studies with isolated canine G cells in primary culture. J Clin Invest 1987 79 : 935 942.
    • (1987) J Clin Invest , vol.79 , pp. 935-942
    • Sugano, K.1    Park, J.2    Soll, A.H.3    Yamada, T.4
  • 34
    • 33845255559 scopus 로고    scopus 로고
    • Gastrin - Active participant or bystander in gastric carcinogenesis?
    • Watson SA, Grabowska AM, El-Zaatari M, Takhar A. Gastrin - active participant or bystander in gastric carcinogenesis? Nat Rev Cancer 2006 6 : 936 946.
    • (2006) Nat Rev Cancer , vol.6 , pp. 936-946
    • Watson, S.A.1    Grabowska, A.M.2    El-Zaatari, M.3    Takhar, A.4
  • 35
  • 36
    • 0027532076 scopus 로고
    • Regulation of intestinal epithelial proliferation: A few answers, many questions
    • Podolsky DK. Regulation of intestinal epithelial proliferation: A few answers, many questions. Am J Physiol 1993 264 : 179 186.
    • (1993) Am J Physiol , vol.264 , pp. 179-186
    • Podolsky, D.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.