-
1
-
-
13844250741
-
High-throughput screens and selections of enzyme-encoding genes
-
Aharoni A., Griffiths A.D., and Tawfik D.S. High-throughput screens and selections of enzyme-encoding genes. Curr. Opin. Chem. Biol. 9 (2005) 210-216
-
(2005)
Curr. Opin. Chem. Biol.
, vol.9
, pp. 210-216
-
-
Aharoni, A.1
Griffiths, A.D.2
Tawfik, D.S.3
-
2
-
-
30744474931
-
Dielectrophoretic manipulation of drops for high-speed microfluidic sorting devices
-
Ahn K., Kerbage C., Hunt T.P., Westervelt R.M., Link D.R., and Weitz D.A. Dielectrophoretic manipulation of drops for high-speed microfluidic sorting devices. Appl. Phys. Lett. 88 (2006) 24104
-
(2006)
Appl. Phys. Lett.
, vol.88
, pp. 24104
-
-
Ahn, K.1
Kerbage, C.2
Hunt, T.P.3
Westervelt, R.M.4
Link, D.R.5
Weitz, D.A.6
-
3
-
-
0033851119
-
Efficient cell infection by Moloney murine leukemia virus-derived particles requires minimal amounts of envelope glycoprotein
-
Bachrach E., Marin M., Pelegrin M., Karavanas G., and Piechaczyk M. Efficient cell infection by Moloney murine leukemia virus-derived particles requires minimal amounts of envelope glycoprotein. J. Virol. 74 (2000) 8480-8486
-
(2000)
J. Virol.
, vol.74
, pp. 8480-8486
-
-
Bachrach, E.1
Marin, M.2
Pelegrin, M.3
Karavanas, G.4
Piechaczyk, M.5
-
4
-
-
67649973848
-
Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity
-
Baret J.C., Miller O.J., Taly V., Ryckelynck M., El-Harrak A., Frenz L., Rick C., Samuels M.L., Hutchison J.B., Agresti J.J., et al. Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity. Lab Chip 9 (2009) 1850-1858
-
(2009)
Lab Chip
, vol.9
, pp. 1850-1858
-
-
Baret, J.C.1
Miller, O.J.2
Taly, V.3
Ryckelynck, M.4
El-Harrak, A.5
Frenz, L.6
Rick, C.7
Samuels, M.L.8
Hutchison, J.B.9
Agresti, J.J.10
-
5
-
-
0034284978
-
Identification of efficiently cleaved substrates for HIV-1 protease using a phage display library and use in inhibitor development
-
Beck Z.Q., Hervio L., Dawson P.E., Elder J.H., and Madison E.L. Identification of efficiently cleaved substrates for HIV-1 protease using a phage display library and use in inhibitor development. Virology 274 (2000) 391-401
-
(2000)
Virology
, vol.274
, pp. 391-401
-
-
Beck, Z.Q.1
Hervio, L.2
Dawson, P.E.3
Elder, J.H.4
Madison, E.L.5
-
6
-
-
0042780350
-
Designing repeat proteins: well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins
-
Binz H.K., Stumpp M.T., Forrer P., Amstutz P., and Pluckthun A. Designing repeat proteins: well-expressed, soluble and stable proteins from combinatorial libraries of consensus ankyrin repeat proteins. J. Mol. Biol. 332 (2003) 489-503
-
(2003)
J. Mol. Biol.
, vol.332
, pp. 489-503
-
-
Binz, H.K.1
Stumpp, M.T.2
Forrer, P.3
Amstutz, P.4
Pluckthun, A.5
-
7
-
-
0030994634
-
Yeast surface display for screening combinatorial polypeptide libraries
-
Boder E.T., and Wittrup K.D. Yeast surface display for screening combinatorial polypeptide libraries. Nat. Biotechnol. 15 (1997) 553-557
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 553-557
-
-
Boder, E.T.1
Wittrup, K.D.2
-
8
-
-
0031787970
-
In vivo selection of protease cleavage sites from retrovirus display libraries
-
Buchholz C.J., Peng K.W., Morling F.J., Zhang J., Cosset F.L., and Russell S.J. In vivo selection of protease cleavage sites from retrovirus display libraries. Nat. Biotechnol. 16 (1998) 951-954
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 951-954
-
-
Buchholz, C.J.1
Peng, K.W.2
Morling, F.J.3
Zhang, J.4
Cosset, F.L.5
Russell, S.J.6
-
10
-
-
0036091692
-
Envelope glycoprotein incorporation, not shedding of surface envelope glycoprotein (gp120/SU), is the primary determinant of SU content of purified human immunodeficiency virus type 1 and simian immunodeficiency virus
-
Chertova E., Bess Jr. J.W., Crise B.J., Sowder I.R., Schaden T.M., Hilburn J.M., Hoxie J.A., Benveniste R.E., Lifson J.D., Henderson L.E., et al. Envelope glycoprotein incorporation, not shedding of surface envelope glycoprotein (gp120/SU), is the primary determinant of SU content of purified human immunodeficiency virus type 1 and simian immunodeficiency virus. J. Virol. 76 (2002) 5315-5325
-
(2002)
J. Virol.
, vol.76
, pp. 5315-5325
-
-
Chertova, E.1
Bess Jr., J.W.2
Crise, B.J.3
Sowder, I.R.4
Schaden, T.M.5
Hilburn, J.M.6
Hoxie, J.A.7
Benveniste, R.E.8
Lifson, J.D.9
Henderson, L.E.10
-
11
-
-
43149111583
-
Droplet-based microfluidic platforms for the encapsulation and screening of mammalian cells and multicellular organisms
-
Clausell-Tormos J., Lieber D., Baret J.C., El-Harrak A., Miller O.J., Frenz L., Blouwolff J., Humphry K.J., Koster S., Duan H., et al. Droplet-based microfluidic platforms for the encapsulation and screening of mammalian cells and multicellular organisms. Chem. Biol. 15 (2008) 427-437
-
(2008)
Chem. Biol.
, vol.15
, pp. 427-437
-
-
Clausell-Tormos, J.1
Lieber, D.2
Baret, J.C.3
El-Harrak, A.4
Miller, O.J.5
Frenz, L.6
Blouwolff, J.7
Humphry, K.J.8
Koster, S.9
Duan, H.10
-
12
-
-
0033582608
-
A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage
-
Demartis S., Huber A., Viti F., Lozzi L., Giovannoni L., Neri P., Winter G., and Neri D. A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage. J. Mol. Biol. 286 (1999) 617-633
-
(1999)
J. Mol. Biol.
, vol.286
, pp. 617-633
-
-
Demartis, S.1
Huber, A.2
Viti, F.3
Lozzi, L.4
Giovannoni, L.5
Neri, P.6
Winter, G.7
Neri, D.8
-
13
-
-
0032832775
-
Drug screening-beyond the bottleneck
-
Dove A. Drug screening-beyond the bottleneck. Nat. Biotechnol. 17 (1999) 859-863
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 859-863
-
-
Dove, A.1
-
14
-
-
0042926892
-
Phage display as a tool for the directed evolution of enzymes
-
Fernandez-Gacio A., Uguen M., and Fastrez J. Phage display as a tool for the directed evolution of enzymes. Trends Biotechnol. 21 (2003) 408-414
-
(2003)
Trends Biotechnol.
, vol.21
, pp. 408-414
-
-
Fernandez-Gacio, A.1
Uguen, M.2
Fastrez, J.3
-
15
-
-
0027425230
-
Production and fluorescence-activated cell sorting of Escherichia coli expressing a functional antibody fragment on the external surface
-
Francisco J.A., Campbell R., Iverson B.L., and Georgiou G. Production and fluorescence-activated cell sorting of Escherichia coli expressing a functional antibody fragment on the external surface. Proc. Natl. Acad. Sci. USA 90 (1993) 10444-10448
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10444-10448
-
-
Francisco, J.A.1
Campbell, R.2
Iverson, B.L.3
Georgiou, G.4
-
16
-
-
33747130345
-
Miniaturising the laboratory in emulsion droplets
-
Griffiths A.D., and Tawfik D.S. Miniaturising the laboratory in emulsion droplets. Trends Biotechnol. 24 (2006) 395-402
-
(2006)
Trends Biotechnol.
, vol.24
, pp. 395-402
-
-
Griffiths, A.D.1
Tawfik, D.S.2
-
17
-
-
0030974119
-
In vitro selection and evolution of functional proteins by using ribosome display
-
Hanes J., and Pluckthun A. In vitro selection and evolution of functional proteins by using ribosome display. Proc. Natl. Acad. Sci. USA 94 (1997) 4937-4942
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4937-4942
-
-
Hanes, J.1
Pluckthun, A.2
-
18
-
-
0030955262
-
Mechanism-based phage display selection of active-site mutants of human glutathione transferase A1-1 catalyzing SNAr reactions
-
Hansson L.O., Widersten M., and Mannervik B. Mechanism-based phage display selection of active-site mutants of human glutathione transferase A1-1 catalyzing SNAr reactions. Biochemistry 36 (1997) 11252-11260
-
(1997)
Biochemistry
, vol.36
, pp. 11252-11260
-
-
Hansson, L.O.1
Widersten, M.2
Mannervik, B.3
-
19
-
-
33645523763
-
Optimizing the affinity and specificity of proteins with molecular display
-
Levin A.M., and Weiss G.A. Optimizing the affinity and specificity of proteins with molecular display. Mol. Biosyst. 2 (2006) 49-57
-
(2006)
Mol. Biosyst.
, vol.2
, pp. 49-57
-
-
Levin, A.M.1
Weiss, G.A.2
-
20
-
-
33644502902
-
Exploring the interaction between the protein kinase A catalytic subunit and caveolin-1 scaffolding domain with shotgun scanning, oligomer complementation, NMR, and docking
-
Levin A.M., Coroneus J.G., Cocco M.J., and Weiss G.A. Exploring the interaction between the protein kinase A catalytic subunit and caveolin-1 scaffolding domain with shotgun scanning, oligomer complementation, NMR, and docking. Protein Sci. 15 (2006) 478-486
-
(2006)
Protein Sci.
, vol.15
, pp. 478-486
-
-
Levin, A.M.1
Coroneus, J.G.2
Cocco, M.J.3
Weiss, G.A.4
-
21
-
-
35349015204
-
Selection of horseradish peroxidase variants with enhanced enantioselectivity by yeast surface display
-
Lipovsek D., Antipov E., Armstrong K.A., Olsen M.J., Klibanov A.M., Tidor B., and Wittrup K.D. Selection of horseradish peroxidase variants with enhanced enantioselectivity by yeast surface display. Chem. Biol. 14 (2007) 1176-1185
-
(2007)
Chem. Biol.
, vol.14
, pp. 1176-1185
-
-
Lipovsek, D.1
Antipov, E.2
Armstrong, K.A.3
Olsen, M.J.4
Klibanov, A.M.5
Tidor, B.6
Wittrup, K.D.7
-
22
-
-
28844487473
-
High-throughput screening of enzyme libraries: in vitro evolution of a beta-galactosidase by fluorescence-activated sorting of double emulsions
-
Mastrobattista E., Taly V., Chanudet E., Treacy P., Kelly B.T., and Griffiths A.D. High-throughput screening of enzyme libraries: in vitro evolution of a beta-galactosidase by fluorescence-activated sorting of double emulsions. Chem. Biol. 12 (2005) 1291-1300
-
(2005)
Chem. Biol.
, vol.12
, pp. 1291-1300
-
-
Mastrobattista, E.1
Taly, V.2
Chanudet, E.3
Treacy, P.4
Kelly, B.T.5
Griffiths, A.D.6
-
23
-
-
11144229400
-
Directed evolution of retrovirus envelope protein cytoplasmic tails guided by functional incorporation into lentivirus particles
-
Merten C.A., Stitz J., Braun G., Poeschla E.M., Cichutek K., and Buchholz C.J. Directed evolution of retrovirus envelope protein cytoplasmic tails guided by functional incorporation into lentivirus particles. J. Virol. 79 (2005) 834-840
-
(2005)
J. Virol.
, vol.79
, pp. 834-840
-
-
Merten, C.A.1
Stitz, J.2
Braun, G.3
Poeschla, E.M.4
Cichutek, K.5
Buchholz, C.J.6
-
24
-
-
33645528964
-
Fusoselect: cell-cell fusion activity engineered by directed evolution of a retroviral glycoprotein
-
Merten C.A., Stitz J., Braun G., Medvedovska J., Cichutek K., and Buchholz C.J. Fusoselect: cell-cell fusion activity engineered by directed evolution of a retroviral glycoprotein. Nucleic Acids Res. 34 (2006) e41
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Merten, C.A.1
Stitz, J.2
Braun, G.3
Medvedovska, J.4
Cichutek, K.5
Buchholz, C.J.6
-
25
-
-
20144371828
-
Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP
-
Nikles D., Bach P., Boller K., Merten C.A., Montrasio F., Heppner F.L., Aguzzi A., Cichutek K., Kalinke U., and Buchholz C.J. Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP. J. Virol. 79 (2005) 4033-4042
-
(2005)
J. Virol.
, vol.79
, pp. 4033-4042
-
-
Nikles, D.1
Bach, P.2
Boller, K.3
Merten, C.A.4
Montrasio, F.5
Heppner, F.L.6
Aguzzi, A.7
Cichutek, K.8
Kalinke, U.9
Buchholz, C.J.10
-
26
-
-
0033772183
-
Function-based isolation of novel enzymes from a large library
-
Olsen M.J., Stephens D., Griffiths D., Daugherty P., Georgiou G., and Iverson B.L. Function-based isolation of novel enzymes from a large library. Nat. Biotechnol. 18 (2000) 1071-1074
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 1071-1074
-
-
Olsen, M.J.1
Stephens, D.2
Griffiths, D.3
Daugherty, P.4
Georgiou, G.5
Iverson, B.L.6
-
27
-
-
0031736826
-
Expression of active human tissue-type plasminogen activator in Escherichia coli
-
Qiu J., Swartz J.R., and Georgiou G. Expression of active human tissue-type plasminogen activator in Escherichia coli. Appl. Environ. Microbiol. 64 (1998) 4891-4896
-
(1998)
Appl. Environ. Microbiol.
, vol.64
, pp. 4891-4896
-
-
Qiu, J.1
Swartz, J.R.2
Georgiou, G.3
-
28
-
-
0030817279
-
RNA-peptide fusions for the in vitro selection of peptides and proteins
-
Roberts R.W., and Szostak J.W. RNA-peptide fusions for the in vitro selection of peptides and proteins. Proc. Natl. Acad. Sci. USA 94 (1997) 12297-12302
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12297-12302
-
-
Roberts, R.W.1
Szostak, J.W.2
-
29
-
-
0033536626
-
Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency
-
Shusta E.V., Kieke M.C., Parke E., Kranz D.M., and Wittrup K.D. Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency. J. Mol. Biol. 292 (1999) 949-956
-
(1999)
J. Mol. Biol.
, vol.292
, pp. 949-956
-
-
Shusta, E.V.1
Kieke, M.C.2
Parke, E.3
Kranz, D.M.4
Wittrup, K.D.5
-
30
-
-
0028175483
-
Selection of beta-lactamase on filamentous bacteriophage by catalytic activity
-
Soumillion P., Jespers L., Bouchet M., Marchand-Brynaert J., Winter G., and Fastrez J. Selection of beta-lactamase on filamentous bacteriophage by catalytic activity. J. Mol. Biol. 237 (1994) 415-422
-
(1994)
J. Mol. Biol.
, vol.237
, pp. 415-422
-
-
Soumillion, P.1
Jespers, L.2
Bouchet, M.3
Marchand-Brynaert, J.4
Winter, G.5
Fastrez, J.6
-
31
-
-
0031854986
-
Man-made cell-like compartments for molecular evolution
-
Tawfik D.S., and Griffiths A.D. Man-made cell-like compartments for molecular evolution. Nat. Biotechnol. 16 (1998) 652-656
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 652-656
-
-
Tawfik, D.S.1
Griffiths, A.D.2
-
32
-
-
0035941477
-
Functional screening of a retroviral peptide library for MHC class I presentation
-
Tolstrup A.B., Duch M., Dalum I., Pedersen F.S., and Mouritsen S. Functional screening of a retroviral peptide library for MHC class I presentation. Gene 263 (2001) 77-84
-
(2001)
Gene
, vol.263
, pp. 77-84
-
-
Tolstrup, A.B.1
Duch, M.2
Dalum, I.3
Pedersen, F.S.4
Mouritsen, S.5
-
33
-
-
0034695405
-
Selection of beta-lactamases and penicillin binding mutants from a library of phage displayed TEM-1 beta-lactamase randomly mutated in the active site omega-loop
-
Vanwetswinkel S., Avalle B., and Fastrez J. Selection of beta-lactamases and penicillin binding mutants from a library of phage displayed TEM-1 beta-lactamase randomly mutated in the active site omega-loop. J. Mol. Biol. 295 (2000) 527-540
-
(2000)
J. Mol. Biol.
, vol.295
, pp. 527-540
-
-
Vanwetswinkel, S.1
Avalle, B.2
Fastrez, J.3
-
34
-
-
33749860977
-
Post-translational modifications in the context of therapeutic proteins
-
Walsh G., and Jefferis R. Post-translational modifications in the context of therapeutic proteins. Nat. Biotechnol. 24 (2006) 1241-1252
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 1241-1252
-
-
Walsh, G.1
Jefferis, R.2
-
35
-
-
0026655099
-
Studies on compartmentation and turnover of murine retrovirus envelope proteins
-
Yu Y., and Wong P.K. Studies on compartmentation and turnover of murine retrovirus envelope proteins. Virology 188 (1992) 477-485
-
(1992)
Virology
, vol.188
, pp. 477-485
-
-
Yu, Y.1
Wong, P.K.2
|