Selection of β-lactamases and penicillin binding mutants from a library of phage displayed TEM-1 β-lactamase randomly mutated in the active site Ω-loop

Journal of Molecular Biology

Volumn 295, Issue 3, 2000, Pages 527-540

  Vanwetswinkel, Sophie ^a   Avalle, Bérangère ^a   Fastrez, Jacques ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Enzyme evolution; Penicillin binding proteins; Phage display; lactamase

Indexed keywords

BETA LACTAMASE; MUTANT PROTEIN; PENICILLIN BINDING PROTEIN;

ARTICLE; BACTERIOPHAGE; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME BINDING; GENE LIBRARY; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

EID: 0034695405     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3376     Document Type: Article

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