F11-mediated inhibition of RhoA signalling enhances the spread of vaccinia virus in vitro and in vivo in an intranasal mouse model of infection

PLoS ONE

Volumn 4, Issue 12, 2009, Pages

  Cordeiro, João V ^a   Guerra, Susana ^b,c   Arakawa, Yoshiki ^a,d   Dodding, Mark P ^a   Esteban, Mariano ^b   Way, Michael ^a  

^a London Research Institute   (United Kingdom)

^b CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^c UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^d KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; VIRUS PROTEIN; ACTIN; F11L PROTEIN, VACCINIA VIRUS; GUANOSINE TRIPHOSPHATE;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMAGING; IN VITRO STUDY; IN VIVO STUDY; LUNG INFECTION; MONOLAYER CULTURE; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SPLEEN DISEASE; VACCINIA; VACCINIA VIRUS; VIRUS TRANSMISSION; ANIMAL; CELL MOTION; DISEASE MODEL; HELA CELL; INTRANASAL DRUG ADMINISTRATION; METABOLISM; PHYSIOLOGY; STRESS FIBER; VIROLOGY;

VACCINIA VIRUS;

ACTINS; ADMINISTRATION, INTRANASAL; ANIMALS; CELL MOVEMENT; DISEASE MODELS, ANIMAL; GUANOSINE TRIPHOSPHATE; HELA CELLS; HUMANS; MICE; PROTEIN BINDING; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; STRESS FIBERS; VACCINIA; VACCINIA VIRUS; VIRAL PROTEINS;

EID: 77949519797     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008506     Document Type: Article

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