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Volumn 62, Issue 1, 2010, Pages 25-34

Ketorolac trometamol topical formulations: Release behaviour, physical characterization, skin permeation, efficacy and gastric safety

Author keywords

Analgesic; Anti inflammatory activity; Ketorolac trometamol; Transdermal delivery

Indexed keywords

KETOROLAC TROMETAMOL;

EID: 77949494608     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp/62.01.0002     Document Type: Article
Times cited : (19)

References (40)
  • 1
    • 0025021284 scopus 로고
    • Ketorolac: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential
    • Buckley MM, Brogden RN. Ketorolac: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential. Drugs 1990; 39: 86-109.
    • (1990) Drugs , vol.39 , pp. 86-109
    • Buckley, M.M.1    Brogden, R.N.2
  • 2
    • 67649224901 scopus 로고    scopus 로고
    • Angeles González-Fernández M. Appropriateness of ketorolac use in a trauma hospital. Rev Calid Asist 2009; 24: 115-123.
    • Angeles González-Fernández M. Appropriateness of ketorolac use in a trauma hospital. Rev Calid Asist 2009; 24: 115-123.
  • 3
    • 0036294327 scopus 로고    scopus 로고
    • A randomised controlled study on the use of anti-inflammatory drugs in patients with cancer pain on morphine therapy: Effects on dose-escalation and a pharmacoeconomic analysis
    • Mercadante S et al. A randomised controlled study on the use of anti-inflammatory drugs in patients with cancer pain on morphine therapy: effects on dose-escalation and a pharmacoeconomic analysis. Eur J Cancer 2002; 38: 1358-1363.
    • (2002) Eur J Cancer , vol.38 , pp. 1358-1363
    • Mercadante, S.1
  • 4
    • 0031787839 scopus 로고    scopus 로고
    • The opioid-sparing effects of intravenous ketorolac as an adjuvant analgesic in cancer pain: Application in bone metastases and the opioid bowel syndrome
    • Joishy SK, Walsh D. The opioid-sparing effects of intravenous ketorolac as an adjuvant analgesic in cancer pain: application in bone metastases and the opioid bowel syndrome. J Pain Symptom Manage 1998; 16: 334-339.
    • (1998) J Pain Symptom Manage , vol.16 , pp. 334-339
    • Joishy, S.K.1    Walsh, D.2
  • 5
    • 0030614836 scopus 로고    scopus 로고
    • Ketorolac: A reappraisal of its pharmacodynamic and pharmacokinetic properties and therapeutic use in pain management
    • Gillis JC, Brogden RN. Ketorolac: a reappraisal of its pharmacodynamic and pharmacokinetic properties and therapeutic use in pain management. Drugs 1997; 53: 139-188.
    • (1997) Drugs , vol.53 , pp. 139-188
    • Gillis, J.C.1    Brogden, R.N.2
  • 6
    • 0042338753 scopus 로고    scopus 로고
    • Percutaneous lidocaine administration via a new iontophoresis system in children: Tolerability and absence of systemic bioavailability
    • Kearns GL et al. Percutaneous lidocaine administration via a new iontophoresis system in children: tolerability and absence of systemic bioavailability. Pediatrics 2003; 112: 578-582.
    • (2003) Pediatrics , vol.112 , pp. 578-582
    • Kearns, G.L.1
  • 7
    • 3142727714 scopus 로고    scopus 로고
    • Transdermal delivery of ketorolac tromethamine: Effects of vehicles and penetration enhancers
    • Cho YA, Gwak HS. Transdermal delivery of ketorolac tromethamine: effects of vehicles and penetration enhancers. Drug Dev Ind Pharm 2004; 30: 557-564.
    • (2004) Drug Dev Ind Pharm , vol.30 , pp. 557-564
    • Cho, Y.A.1    Gwak, H.S.2
  • 8
    • 14844328700 scopus 로고    scopus 로고
    • Proniosomes as a drug carrier for transdermal delivery of ketorolac
    • Alsarra IA et al. Proniosomes as a drug carrier for transdermal delivery of ketorolac. Eur J Pharm Biopharm 2005; 59: 485-490.
    • (2005) Eur J Pharm Biopharm , vol.59 , pp. 485-490
    • Alsarra, I.A.1
  • 9
    • 63649131873 scopus 로고    scopus 로고
    • Potential of cyclodextrin complexation and liposomes in topical delivery of ketorolac: In vitro and in vivo evaluation
    • Nagarsenker MS et al. Potential of cyclodextrin complexation and liposomes in topical delivery of ketorolac: in vitro and in vivo evaluation. AAPS PharmSciTech 2008; 9: 1165-1170.
    • (2008) AAPS PharmSciTech , vol.9 , pp. 1165-1170
    • Nagarsenker, M.S.1
  • 10
    • 15044355680 scopus 로고    scopus 로고
    • Ketorolac amide prodrugs for transdermal delivery: Stability and in vitro rat skin permeation studies
    • Kim BY et al. Ketorolac amide prodrugs for transdermal delivery: stability and in vitro rat skin permeation studies. Int J Pharm 2005; 293: 193-202.
    • (2005) Int J Pharm , vol.293 , pp. 193-202
    • Kim, B.Y.1
  • 11
    • 0038006697 scopus 로고    scopus 로고
    • Investigation into the potential of iontophoresis facilitated delivery of ketorolac
    • Tiwari SB, Udupa N. Investigation into the potential of iontophoresis facilitated delivery of ketorolac. Int J Pharm 2003; 260: 93-103.
    • (2003) Int J Pharm , vol.260 , pp. 93-103
    • Tiwari, S.B.1    Udupa, N.2
  • 12
    • 43049101077 scopus 로고    scopus 로고
    • Anti-hyperalgesic and anti-inflammatory effects of ketorolac tromethamine gel using pulsed ultrasound in inflamed rats
    • Yang J et al. Anti-hyperalgesic and anti-inflammatory effects of ketorolac tromethamine gel using pulsed ultrasound in inflamed rats. Arch Pharm Res 2008; 31: 511-517.
    • (2008) Arch Pharm Res , vol.31 , pp. 511-517
    • Yang, J.1
  • 13
    • 0024821282 scopus 로고
    • Studies on microemulsions using brij as surfactant and glycerin, ethylene glycol and propylene glycol as cosurfactants
    • Kale NJ, Allen LV. Studies on microemulsions using brij as surfactant and glycerin, ethylene glycol and propylene glycol as cosurfactants. Int J Pharm 1989; 57: 87-93.
    • (1989) Int J Pharm , vol.57 , pp. 87-93
    • Kale, N.J.1    Allen, L.V.2
  • 14
    • 0035806281 scopus 로고    scopus 로고
    • Topical transport of hydrophilic compounds using water in oil nanoemulsions
    • Wu H et al. Topical transport of hydrophilic compounds using water in oil nanoemulsions. Int J Pharm 2001; 220: 63-75.
    • (2001) Int J Pharm , vol.220 , pp. 63-75
    • Wu, H.1
  • 15
    • 0032947897 scopus 로고    scopus 로고
    • Pharmacokinetic profile of a new matrix-type transdermal delivery system: Diclofenac diethyl ammonium patch
    • Devi K, Paranjothy KL. Pharmacokinetic profile of a new matrix-type transdermal delivery system: diclofenac diethyl ammonium patch. Drug Dev Ind Pharm 1999; 25: 695-700.
    • (1999) Drug Dev Ind Pharm , vol.25 , pp. 695-700
    • Devi, K.1    Paranjothy, K.L.2
  • 16
    • 73049134701 scopus 로고
    • Rate of release of medicaments from ointment bases containing drugs in suspension
    • Higuchi T. Rate of release of medicaments from ointment bases containing drugs in suspension. J Pharm Sci 1961; 50: 874-875.
    • (1961) J Pharm Sci , vol.50 , pp. 874-875
    • Higuchi, T.1
  • 17
    • 0034660379 scopus 로고    scopus 로고
    • Delivery of nalbuphine and its prodrugs across skin by passive diffusion and iontophoresis
    • Sung KC. Delivery of nalbuphine and its prodrugs across skin by passive diffusion and iontophoresis. J Control Release 2000; 67: 1-8.
    • (2000) J Control Release , vol.67 , pp. 1-8
    • Sung, K.C.1
  • 18
    • 85041691678 scopus 로고    scopus 로고
    • Factorial design approach for optimization of a gel formulation for in-vitro iontophoretic transdermal delivery of granisetron
    • Habib BA et al. Factorial design approach for optimization of a gel formulation for in-vitro iontophoretic transdermal delivery of granisetron. Bull Fac Pharm 2008; 46: 305-313.
    • (2008) Bull Fac Pharm , vol.46 , pp. 305-313
    • Habib, B.A.1
  • 19
    • 0029134660 scopus 로고
    • Transdermal delivery of ketorolac tromethamine: Permeation enhancement, device design, and pharmacokinetics in healthy humans
    • Roy SD, Manoukian E. Transdermal delivery of ketorolac tromethamine: permeation enhancement, device design, and pharmacokinetics in healthy humans. J Pharm Sci 1995; 84: 1190-1196.
    • (1995) J Pharm Sci , vol.84 , pp. 1190-1196
    • Roy, S.D.1    Manoukian, E.2
  • 20
    • 0142060262 scopus 로고    scopus 로고
    • Enhanced iontophoretic delivery of buspirone hydrochloride across human skin using chemical enhancers
    • Meidan VM et al. Enhanced iontophoretic delivery of buspirone hydrochloride across human skin using chemical enhancers. Int J Pharm 2003; 264: 73-83.
    • (2003) Int J Pharm , vol.264 , pp. 73-83
    • Meidan, V.M.1
  • 21
    • 34247539073 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of the transdermal iontophoretic delivery of sumatriptan succinate
    • Patel SR et al. In vitro and in vivo evaluation of the transdermal iontophoretic delivery of sumatriptan succinate. Eur J Pharm Biopharm 2007; 66: 296-301.
    • (2007) Eur J Pharm Biopharm , vol.66 , pp. 296-301
    • Patel, S.R.1
  • 23
    • 0025976974 scopus 로고
    • Studies of hyperalgesia induced by Trypanosoma brucei brucei infection in rats
    • Wiesenfeld-Hallin Z et al. Studies of hyperalgesia induced by Trypanosoma brucei brucei infection in rats. Acta Trop 1991; 48: 215-222.
    • (1991) Acta Trop , vol.48 , pp. 215-222
    • Wiesenfeld-Hallin, Z.1
  • 24
    • 84960959252 scopus 로고
    • A method for measurement of analgesic activity on inflamed tissue
    • Randall LO, Selitto JJ. A method for measurement of analgesic activity on inflamed tissue. Arch Int Pharmacodyn Ther 1957; 111: 409-419.
    • (1957) Arch Int Pharmacodyn Ther , vol.111 , pp. 409-419
    • Randall, L.O.1    Selitto, J.J.2
  • 25
    • 84904331163 scopus 로고
    • Effect of alteration in side chain upon anti-inflammatory and liver glycogen activities in hydrocortisone ester
    • Winter CA, Porter CC. Effect of alteration in side chain upon anti-inflammatory and liver glycogen activities in hydrocortisone ester. J Am Pharmacol Soc 1957; 46: 515-519.
    • (1957) J Am Pharmacol Soc , vol.46 , pp. 515-519
    • Winter, C.A.1    Porter, C.C.2
  • 26
    • 76549202698 scopus 로고
    • Further studies concerning the participation of adrenal cortex in the pathogenesis of arthritis
    • Seyle H. Further studies concerning the participation of adrenal cortex in the pathogenesis of arthritis. Br Med J 1949; 2: 1129-1135.
    • (1949) Br Med J , vol.2 , pp. 1129-1135
    • Seyle, H.1
  • 27
    • 0028199216 scopus 로고
    • Pentoxifylline prevents indomethacin induced acute gastric mucosal damage in rats: Role of tumour necrosis factor alpha
    • Santucci L et al. Pentoxifylline prevents indomethacin induced acute gastric mucosal damage in rats: role of tumour necrosis factor alpha. Gut 1994; 35: 909-915.
    • (1994) Gut , vol.35 , pp. 909-915
    • Santucci, L.1
  • 28
    • 0026692072 scopus 로고
    • Reduction of aspirin induced gastric damage in rats by interleukin-1B; possible involvement of endogenous corticosteroids
    • Perretti et al. Reduction of aspirin induced gastric damage in rats by interleukin-1B; possible involvement of endogenous corticosteroids. J Pharmacol Exp Ther 1992; 261: 1238-1247.
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 1238-1247
    • Perretti1
  • 29
    • 33847152136 scopus 로고    scopus 로고
    • Rheological behavior of gels and meloxicam release
    • Ruiz Martinez MA et al. Rheological behavior of gels and meloxicam release. Int J Pharm 2007; 333: 17-23.
    • (2007) Int J Pharm , vol.333 , pp. 17-23
    • Ruiz Martinez, M.A.1
  • 30
    • 73049177744 scopus 로고
    • Analysis of data on the medicament release from ointments
    • Higuchi WI. Analysis of data on the medicament release from ointments. J Pharm Sci 1962; 51: 802-804.
    • (1962) J Pharm Sci , vol.51 , pp. 802-804
    • Higuchi, W.I.1
  • 31
    • 42649104349 scopus 로고    scopus 로고
    • Rheological and functional characterization of new anti-inflammatory delivery system designed for buccal administration
    • Perioli L. Rheological and functional characterization of new anti-inflammatory delivery system designed for buccal administration. Int J Pharm 2008; 356: 19-28.
    • (2008) Int J Pharm , vol.356 , pp. 19-28
    • Perioli, L.1
  • 32
    • 0033047010 scopus 로고    scopus 로고
    • Role of dissolution studies in controlled release drug delivery system
    • Sood A, Panchagnula R. Role of dissolution studies in controlled release drug delivery system. STP Pharmaceutical Science 1999; 9: 157-168.
    • (1999) STP Pharmaceutical Science , vol.9 , pp. 157-168
    • Sood, A.1    Panchagnula, R.2
  • 33
    • 0027939922 scopus 로고
    • The influence of co solvents on the in-vitro percutaneous penetration of diclofenac sodium from a gel system
    • Ho HO et al. The influence of co solvents on the in-vitro percutaneous penetration of diclofenac sodium from a gel system. J Pharm Pharmacol 1994; 46: 636-642.
    • (1994) J Pharm Pharmacol , vol.46 , pp. 636-642
    • Ho, H.O.1
  • 34
    • 0029874141 scopus 로고    scopus 로고
    • The relative effect of azone and transcutol on permeant diffusivity and solubility in human stratum corneum
    • Harrison JE et al. The relative effect of azone and transcutol on permeant diffusivity and solubility in human stratum corneum. Pharm Res 1996; 13: 542-546.
    • (1996) Pharm Res , vol.13 , pp. 542-546
    • Harrison, J.E.1
  • 35
    • 0035834177 scopus 로고    scopus 로고
    • Transdermal delivery of ketoprofen using microemulsions
    • Rhee YS et al. Transdermal delivery of ketoprofen using microemulsions. Int J Pharm 2001; 228: 161-170.
    • (2001) Int J Pharm , vol.228 , pp. 161-170
    • Rhee, Y.S.1
  • 36
    • 77949523042 scopus 로고    scopus 로고
    • Abd El-Bary A et al. Bioavailability of sulbutamol from different suppository formulations. Egypt Journal of Pharmaceutical Science 1992; 33: 1031-1043.
    • Abd El-Bary A et al. Bioavailability of sulbutamol from different suppository formulations. Egypt Journal of Pharmaceutical Science 1992; 33: 1031-1043.
  • 37
    • 0028911315 scopus 로고
    • Submicron emulsion vehicle for enhanced transdermal delivery of steroidal and nonsteroidal anti-inflammatory drugs
    • Friedman DI et al. Submicron emulsion vehicle for enhanced transdermal delivery of steroidal and nonsteroidal anti-inflammatory drugs. J Pharm Sci 1995; 84: 324-329.
    • (1995) J Pharm Sci , vol.84 , pp. 324-329
    • Friedman, D.I.1
  • 38
    • 0032550357 scopus 로고    scopus 로고
    • Effect of oleic acid/ethanol and oleic acid/propylene glycol on the percutaneous absorption of 5-fluorouracil and tamoxifen and the macroscopic barrier property of porcine epidermis
    • Gao S, Singh J. Effect of oleic acid/ethanol and oleic acid/propylene glycol on the percutaneous absorption of 5-fluorouracil and tamoxifen and the macroscopic barrier property of porcine epidermis. Int J Pharm 1998; 165: 45-55.
    • (1998) Int J Pharm , vol.165 , pp. 45-55
    • Gao, S.1    Singh, J.2
  • 39
    • 0029688250 scopus 로고    scopus 로고
    • Comparison of analgesic effect of locally and systemically administered ketorolac in mastectomy patients
    • Bosek V, Cox CE. Comparison of analgesic effect of locally and systemically administered ketorolac in mastectomy patients. Ann Surg Oncol 1996; 3: 62-66.
    • (1996) Ann Surg Oncol , vol.3 , pp. 62-66
    • Bosek, V.1    Cox, C.E.2
  • 40
    • 0035108465 scopus 로고    scopus 로고
    • In vitro based index of topical anti-inflammatory activity to compare a series of NSAIDs
    • Cordero JA. In vitro based index of topical anti-inflammatory activity to compare a series of NSAIDs. Eur J Pharm Biopharm 2001; 51: 135-142.
    • (2001) Eur J Pharm Biopharm , vol.51 , pp. 135-142
    • Cordero, J.A.1


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