Stereoselective synthesis and biological evaluation of syn-1-amino-3-[18F]fluorocyclobutyl-1-carboxylic acid as a potential positron emission tomography brain tumor imaging agent

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 5, 2009, Pages 1982-1990

  Yu, Weiping ^a   Williams, Larry ^a   Camp, Vernon M ^a   Malveaux, Eugene ^a   Olson, Jeffrey J ^a   Goodman, Mark M ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amino acid transporter; Fluorine 18; PET; syn FACBC

Indexed keywords

1 AMINO 3 FLUOROCYCLOBUTYL 1 CARBOXYLIC ACID F 18; CYCLOBUTANE DERIVATIVE; FLUORINE 18; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN TUMOR; CHEMICAL REACTION; CONTROLLED STUDY; DIAGNOSTIC VALUE; DRUG SYNTHESIS; GLIOSARCOMA; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RAT; STEREOCHEMISTRY; TUMOR DIAGNOSIS;

AMINO ACIDS; ANIMALS; BRAIN NEOPLASMS; CARBOXYLIC ACIDS; CELL LINE, TUMOR; ISOTOPE LABELING; OCTANES; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RATS; STEREOISOMERISM;

RATTUS;

EID: 61349145115     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.01.032     Document Type: Article

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