EM012, a microtubule-interfering agent, inhibits the progression of multidrug-resistant human ovarian cancer both in cultured cells and in athymic nude mice

Cancer Chemotherapy and Pharmacology

Volumn 55, Issue 5, 2005, Pages 461-465

  Zhou, Jun ^a   Liu, Min ^a   Luthra, Roopa ^a   Jones, Jeremy ^a,b   Aneja, Ritu ^c,d   Chandra, Ramesh ^d   Tekmal, Rajeshwar R ^a,b   Joshi, Harish C ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

^c UNIVERSITY OF DELHI   (India)

^d UNIVERSITY OF DELHI   (India)

Author keywords

Cell cycle; EM012; Multidrug resistance; Ovarian cancer

Indexed keywords

ANTINEOPLASTIC AGENT; EM 011; EM 012; GLYCOPROTEIN P; NOSCAPINE; PACLITAXEL; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; FEMALE; HUMAN; HUMAN CELL; MICROTUBULE; MITOSIS INHIBITION; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; NUDE MOUSE; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; TOXICITY; TUMOR XENOGRAFT;

ANIMALS; APOPTOSIS; BENZOFURANS; DRUG RESISTANCE, NEOPLASM; FEMALE; FLOW CYTOMETRY; HUMANS; ISOQUINOLINES; MICE; MICE, NUDE; MICROTUBULES; OVARIAN NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 17644390209     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-004-0903-1     Document Type: Article

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