A small molecule receptor that selectively recognizes trimethyl lysine in a histone peptide with native protein-like affinity

Chemical Communications

Volumn 46, Issue 11, 2010, Pages 1839-1841

  Ingerman, Lindsey A ^a   Cuellar, Matthew E ^b   Waters, Marcey L ^a  

^a The University of North Carolina at Chapel Hill   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; RECEPTOR;

ANISOTROPY; ARTICLE; BINDING AFFINITY; COMBINATORIAL CHEMISTRY; COMBINATORIAL LIBRARY; DISSOCIATION CONSTANT; METHYLATION; MOLECULAR RECOGNITION; PROTEIN BINDING; PROTEIN PROCESSING; PROTEIN STRUCTURE; RECEPTOR BINDING; SENSOR;

EID: 77949416398     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/c000255k     Document Type: Article

References (26)

1. (a) S. R. Bhaumik, E. Smith and A. Shilatifard, Nat. Struct. Mol. Biol., 2007, 14, 1008-1016;
2. (b) G. G. Wang, C. D. Allis and P. Chi, Trends Mol. Med., 2007, 13, 363-372.
3. (a) T. Jenuwein and C. D. Allis, Science, 2001, 293, 1074-1080;
4. (b) T. Kouzarides, Cell, 2007, 128, 693-705.
5. C. Martin and Y. Zhang, Nat. Rev. Mol. Cell Biol., 2005, 6, 838-849.
6. (a) S. A. Jacobs and S. Khorasanizadeh, Science, 2002, 295, 2080-2083;
7. (b) P. R. Nielsen, D. Nietlispach, H. R. Mott, J. Callaghan, A. Bannister, T. Kouzarides, A. G. Murzin, N. V. Murzina and E. D. Laue, Nature, 2002, 416, 103-107;
8. (c) R. M. Hughes, K. R. Wiggins, S. Khorasanizadeh and M. L. Waters, Proc. Natl. Acad. Sci. U. S. A., 2007, 104, 11184-11188;
9. (d) For a review of cation-π interactions, see: J. C. Ma and D. A. Dougherty, Chem. Rev., 1997, 97, 1303-1327.
10. (a) N. Blow, Nature, 2007, 447, 741-744;
11. (b) C. C. Kazanecki, A. J. Kowalski, T. Ding, S. R. Rittling and D. T. Denhardt, J. Cell. Biochem., 2007, 102, 925-935.
12. B. A. R. Williams, L. Lin, S. M. Lindsay and J. C. Chaput, J. Am. Chem. Soc., 2009, 106, 6330-6331.
13. C. S. Beshara, C. E. Jones, K. D. Daze, B. J. Lilgert and F. Hof, ChemBioChem, 2009, 11, 63-66.
14. For reviews, see: (a) P. T. Corbett, J. Leclaire, L. Vial, K. R. West, J.-L. Wietor, J. K. M. Sanders and S. Otto, Chem. Rev., 2006, 106, 3652-3711;
15. (b) J.-M. Lehn, Chem.-Eur. J., 1999, 5, 2455-2463;
16. (c) S. Ladame, Org. Biomol. Chem., 2008, 6, 219-226;
17. (d) R. F. Ludlow and S. Otto, Chem. Soc. Rev., 2008, 37, 101-108;
18. (e) S. Otto, Curr. Opin. Drug Discovery Dev., 2003, 6, 509-520.
19. (a) S. Otto, R. L. E. Furlan and J. K. M. Sanders, J. Am. Chem. Soc., 2000, 122, 12063-12064;
20. (b) O. Ramström and J.-M. Lehn, ChemBioChem, 2000, 1, 41-48.
21. (a) S. Otto, R. L. E. Furlan and J. K. M. Sanders, Science, 2002, 297, 590-593;
22. (b) P. T. Corbett, J. K. M. Sanders and S. Otto, Chem.-Eur. J., 2008, 14, 2153-2166.
23. (a) R.M. Hughes,M. L. Benshoff and M. L. Waters, Chem.-Eur. J., 2007, 13, 5753-5764;
24. (b) L. M. Salonen, C. Bucher, D. W. Banner, W. Haap, J.-L. Mary, J. Benz, O. Kuster, P. l. Seiler, W. B. Schweizer and F. Diederich, Angew. Chem., Int. Ed., 2009, 48, 811-814;
25. (c) A. L. Whiting, N. M. Neufeld and F. Hof, Tetrahedron Lett., 2009, 50, 7035-7037.
26. J. Huang and S. L. Berger, Curr. Opin. Genet. Dev., 2008, 18, 152-158.