Binding investigation of integrin αvß 3with its inhibitors by spr technology and molecular docking simulation

Journal of Biomolecular Screening

Volumn 15, Issue 2, 2010, Pages 131-137

  Yaqin, Liu ^a,b   Yuanjiang, Pan ^a   Xu, Yuhong ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Integrin inhibitors; Molecular docking simulation; Rgd motif; SPR

Indexed keywords

ARGINYLGLYCYLASPARTIC ACID; CELL SURFACE RECEPTOR; CYCLOPEPTIDE; INTEGRIN INHIBITOR; LEUCINE; LIGAND; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ANGIOGENESIS; ARTICLE; BINDING SITE; BIOSENSOR; BIOTECHNOLOGY; CANCER THERAPY; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; DRUG TARGETING; MOLECULAR DOCKING; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN MOTIF; SURFACE PLASMON RESONANCE; THREE DIMENSIONAL IMAGING;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; COMPUTER SIMULATION; HUMANS; INTEGRIN ALPHAVBETA3; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES, CYCLIC; PROTEIN BINDING; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PLASMON RESONANCE;

EID: 77949385211     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057109356207     Document Type: Article

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